6WCZ
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![BU of 6wcz by Molmil](/molmil-images/mine/6wcz) | CryoEM structure of full-length ZIKV NS5-hSTAT2 complex | 分子名称: | Non-structural protein 5, Signal transducer and activator of transcription 2, ZINC ION | 著者 | Boxiao, W, Stephanie, T, Kang, Z, Maria, T.S, Jian, F, Jiuwei, L, Linfeng, G, Wendan, R, Yanxiang, C, Ethan, C.V, HeaJin, H, Matthew, J.E, Sean, E.O, Adolfo, G.S, Hong, Z, Rong, H, Jikui, S. | 登録日 | 2020-03-31 | 公開日 | 2020-07-08 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structural basis for STAT2 suppression by flavivirus NS5. Nat.Struct.Mol.Biol., 27, 2020
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6ZYB
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8OYY
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7NSP
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5J3Q
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![BU of 5j3q by Molmil](/molmil-images/mine/5j3q) | Crystal structure of S. pombe Dcp1:Edc1 mRNA decapping complex | 分子名称: | Edc1, mRNA-decapping enzyme subunit 1 | 著者 | Valkov, E, Muthukumar, S, Chang, C.T, Jonas, S, Weichenrieder, O, Izaurralde, E. | 登録日 | 2016-03-31 | 公開日 | 2016-05-18 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | Structure of the Dcp2-Dcp1 mRNA-decapping complex in the activated conformation. Nat.Struct.Mol.Biol., 23, 2016
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4X8A
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![BU of 4x8a by Molmil](/molmil-images/mine/4x8a) | NavMS pore and C-terminal domain grown from protein purified in LiCl | 分子名称: | HEGA-10, Ion transport protein, NONAETHYLENE GLYCOL, ... | 著者 | Naylor, C.E, Bagneris, C, Wallace, B.A. | 登録日 | 2014-12-10 | 公開日 | 2016-03-09 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.02 Å) | 主引用文献 | Molecular basis of ion permeability in a voltage-gated sodium channel. Embo J., 35, 2016
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8BY4
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6VY6
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8Q9T
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![BU of 8q9t by Molmil](/molmil-images/mine/8q9t) | CryoEM structure of a S. Cerevisiae Ski238 complex bound to RNA | 分子名称: | Antiviral helicase SKI2, Antiviral protein SKI8, RNA (5'-R(P*UP*UP*UP*U)-3'), ... | 著者 | Keidel, A, Koegel, A, Reichelt, P, Kowalinski, E, Schaefer, I.B, Conti, E. | 登録日 | 2023-08-21 | 公開日 | 2023-11-29 | 実験手法 | ELECTRON MICROSCOPY (2.84 Å) | 主引用文献 | Concerted structural rearrangements enable RNA channeling into the cytoplasmic Ski238-Ski7-exosome assembly. Mol.Cell, 83, 2023
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6VY5
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6Q4D
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![BU of 6q4d by Molmil](/molmil-images/mine/6q4d) | CDK2 in complex with FragLite31 | 分子名称: | 2-(4-bromanyl-2-methoxy-phenyl)ethanoic acid, Cyclin-dependent kinase 2 | 著者 | Wood, D.J, Martin, M.P, Noble, M.E.M. | 登録日 | 2018-12-05 | 公開日 | 2019-03-20 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.07 Å) | 主引用文献 | FragLites-Minimal, Halogenated Fragments Displaying Pharmacophore Doublets. An Efficient Approach to Druggability Assessment and Hit Generation. J.Med.Chem., 62, 2019
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8P4X
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![BU of 8p4x by Molmil](/molmil-images/mine/8p4x) | FAD_ox bound dark state structure of PdLCry | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, MAGNESIUM ION, Putative light-receptive cryptochrome (Fragment) | 著者 | Behrmann, E, Behrmann, H. | 登録日 | 2023-05-23 | 公開日 | 2023-11-08 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.57 Å) | 主引用文献 | A marine cryptochrome with an inverse photo-oligomerization mechanism. Nat Commun, 14, 2023
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7STA
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8F7P
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![BU of 8f7p by Molmil](/molmil-images/mine/8f7p) | BRAF kinase in complex with LXH254 (naporafenib) | 分子名称: | N-{3-[2-(2-hydroxyethoxy)-6-(morpholin-4-yl)pyridin-4-yl]-4-methylphenyl}-2-(trifluoromethyl)pyridine-4-carboxamide, Serine/threonine-protein kinase B-raf | 著者 | Tkacik, E, Li, K, Gonzalez Del-Pino, G, Eck, M.J. | 登録日 | 2022-11-20 | 公開日 | 2023-04-12 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.74 Å) | 主引用文献 | Structure and RAF family kinase isoform selectivity of type II RAF inhibitors tovorafenib and naporafenib. J.Biol.Chem., 299, 2023
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6Q8M
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![BU of 6q8m by Molmil](/molmil-images/mine/6q8m) | GH10 endo-xylanase | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-xylanase, ... | 著者 | Davies, G.J, Rowland, R.J, Wu, L, Moroz, O, Blagova, E. | 登録日 | 2018-12-15 | 公開日 | 2019-06-05 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | 主引用文献 | Dynamic and Functional Profiling of Xylan-Degrading Enzymes inAspergillusSecretomes Using Activity-Based Probes. Acs Cent.Sci., 5, 2019
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6OEC
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![BU of 6oec by Molmil](/molmil-images/mine/6oec) | Yeast Spc42 Trimeric Coiled-Coil Amino Acids 181-211 fused to PDB: 3H5I | 分子名称: | CALCIUM ION, Response regulator/sensory box protein/GGDEF domain protein,Spindle pole body component SPC42 | 著者 | Drennan, A.C, Shivaani, K, Seeger, M.A, Andreas, M.P, Gardner, J.M, Sether, E.K.R, Jasperson, S.L, Rayment, I. | 登録日 | 2019-03-27 | 公開日 | 2019-04-24 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.514 Å) | 主引用文献 | Structure and function of Spc42 coiled-coils in yeast centrosome assembly and duplication. Mol.Biol.Cell, 30, 2019
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6X40
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![BU of 6x40 by Molmil](/molmil-images/mine/6x40) | Human GABAA receptor alpha1-beta2-gamma2 subtype in complex with GABA plus picrotoxin | 分子名称: | (1aR,2aR,3S,6R,6aS,8aS,8bR,9R)-2a-hydroxy-8b-methyl-9-(prop-1-en-2-yl)hexahydro-3,6-methano-1,5,7-trioxacyclopenta[ij]c yclopropa[a]azulene-4,8(3H)-dione, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Kim, J.J, Gharpure, A, Teng, J, Zhuang, Y, Howard, R.J, Zhu, S, Noviello, C.M, Walsh, R.M, Lindahl, E, Hibbs, R.E. | 登録日 | 2020-05-21 | 公開日 | 2020-09-09 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (2.86 Å) | 主引用文献 | Shared structural mechanisms of general anaesthetics and benzodiazepines. Nature, 585, 2020
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6OJ0
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![BU of 6oj0 by Molmil](/molmil-images/mine/6oj0) | Cryo-EM reconstruction of Sulfolobus polyhedral virus 1 (SPV1) | 分子名称: | Structural protein VP4, Uncharacterized protein | 著者 | Wang, F, Liu, Y, Conway, J.F, Krupovic, M, Prangishvili, D, Egelman, E.H. | 登録日 | 2019-04-10 | 公開日 | 2019-10-02 | 最終更新日 | 2020-01-08 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | A packing for A-form DNA in an icosahedral virus. Proc.Natl.Acad.Sci.USA, 116, 2019
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8FN2
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![BU of 8fn2 by Molmil](/molmil-images/mine/8fn2) | The structure of a 50S ribosomal subunit in the Lyme disease pathogen Borreliella burgdorferi | 分子名称: | 23S ribosomal RNA, 50S ribosomal protein L10, 50S ribosomal protein L11, ... | 著者 | Sharma, M.R, Manjari, S.R, Agrawal, E.K, Keshavan, P, Koripella, R.K, Majumdar, S, Marcinkiewicz, A.L, Lin, Y.P, Agrawal, R.K, Banavali, N.K. | 登録日 | 2022-12-26 | 公開日 | 2023-11-08 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | The structure of a hibernating ribosome in a Lyme disease pathogen. Nat Commun, 14, 2023
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6T6M
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![BU of 6t6m by Molmil](/molmil-images/mine/6t6m) | Y201W mutant of the orange carotenoid protein from Synechocystis at pH 5.5 | 分子名称: | GLYCEROL, HISTIDINE, Orange carotenoid-binding protein, ... | 著者 | Sluchanko, N.N, Gushchin, I, Botnarevskiy, V.S, Slonimskiy, Y.B, Remeeva, A, Kovalev, K, Stepanov, A.V, Gordeliy, V, Maksimov, E.G. | 登録日 | 2019-10-18 | 公開日 | 2020-11-18 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | 主引用文献 | Role of hydrogen bond alternation and charge transfer states in photoactivation of the Orange Carotenoid Protein. Commun Biol, 4, 2021
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7TBU
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![BU of 7tbu by Molmil](/molmil-images/mine/7tbu) | Crystal structure of the 5-enolpyruvate-shikimate-3-phosphate synthase (EPSPS) domain of Aro1 from Candida albicans in complex with shikimate-3-phosphate | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5-enolpyruvylshikimate-3-phosphate synthase, SHIKIMATE-3-PHOSPHATE | 著者 | Stogios, P.J, Evdokimova, E, Michalska, K, Di Leo, R, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2021-12-22 | 公開日 | 2022-03-16 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Molecular analysis and essentiality of Aro1 shikimate biosynthesis multi-enzyme in Candida albicans. Life Sci Alliance, 5, 2022
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7TBV
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![BU of 7tbv by Molmil](/molmil-images/mine/7tbv) | Crystal structure of the shikimate kinase + 3-dehydroquinate dehydratase + 3-dehydroshikimate dehydrogenase domains of Aro1 from Candida albicans | 分子名称: | CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ... | 著者 | Stogios, P.J, Evdokimova, E, Michalska, K, Di Leo, R, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2021-12-22 | 公開日 | 2022-03-16 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Molecular analysis and essentiality of Aro1 shikimate biosynthesis multi-enzyme in Candida albicans. Life Sci Alliance, 5, 2022
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6QGI
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![BU of 6qgi by Molmil](/molmil-images/mine/6qgi) | Crystal structure of VP5 from Haloarchaeal pleomorphic virus 2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, VP5 | 著者 | El Omari, K, Walter, T.S, Harlos, K, Grimes, J.M, Stuart, D.I, Roine, E. | 登録日 | 2019-01-11 | 公開日 | 2019-02-27 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.46 Å) | 主引用文献 | The structure of a prokaryotic viral envelope protein expands the landscape of membrane fusion proteins. Nat Commun, 10, 2019
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6QGL
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![BU of 6qgl by Molmil](/molmil-images/mine/6qgl) | Crystal structure of VP5 from Haloarchaeal pleomorphic virus 6 | 分子名称: | BROMIDE ION, VP5 | 著者 | El Omari, K, Walter, T.S, Harlos, K, Grimes, J.M, Stuart, D.I, Roine, E. | 登録日 | 2019-01-11 | 公開日 | 2019-02-27 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | 主引用文献 | The structure of a prokaryotic viral envelope protein expands the landscape of membrane fusion proteins. Nat Commun, 10, 2019
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5M95
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![BU of 5m95 by Molmil](/molmil-images/mine/5m95) | STAPHYLOCOCCUS CAPITIS DIVALENT METAL ION TRANSPORTER (DMT) IN COMPLEX WITH MANGANESE | 分子名称: | CAMELID ANTIBODY FRAGMENT, NANOBODY, Divalent metal cation transporter MntH, ... | 著者 | Ehrnstorfer, I.A, Geertsma, E.R, Pardon, E, Steyaert, J, Dutzler, R. | 登録日 | 2016-10-31 | 公開日 | 2016-11-30 | 最終更新日 | 2019-09-25 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Crystal Structure Of A Slc11 (Nramp) Transporter Reveals The Basis For Transition-Metal Ion Transport. Nat.Struct.Mol.Biol., 21, 2014
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