7L3R
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7QP2
| 1-deazaguanosine modified-RNA Sarcin Ricin Loop | Descriptor: | GLYCEROL, RNA (27-MER) | Authors: | Ennifar, E, Micura, R, Bereiter, R, Renard, E, Kreutz, C. | Deposit date: | 2021-12-30 | Release date: | 2022-07-20 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (0.9 Å) | Cite: | 1-Deazaguanosine-Modified RNA: The Missing Piece for Functional RNA Atomic Mutagenesis. J.Am.Chem.Soc., 144, 2022
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7QSH
| 23S ribosomal RNA Sarcin Ricin Loop 27-nt fragment containing a Xanthosine residue at position 2648 | Descriptor: | 23S ribosomal RNA Sarcin Ricin Loop 27-nucleotide fragment, 9-[(2~{R},3~{R},4~{S},5~{R})-3,4-bis(oxidanyl)-5-[[tris(oxidanyl)-$l^{5}-phosphanyl]oxymethyl]oxolan-2-yl]-2-oxidanyl-1~{H}-purin-6-one, GLYCEROL, ... | Authors: | Ennifar, E, Micura, R. | Deposit date: | 2022-01-13 | Release date: | 2023-01-25 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (0.86 Å) | Cite: | Towards a comprehensive understanding of RNA deamination: synthesis and properties of xanthosine-modified RNA. Nucleic Acids Res., 50, 2022
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7QTN
| Duplex RNA containing Xanthosine-Cytosine base pairs | Descriptor: | RNA (5'-R(*GP*GP*UP*AP*(RY)P*UP*GP*CP*GP*(XAN)P*UP*AP*CP*C)-3'), RNA (5'-R(*GP*GP*UP*AP*CP*UP*GP*CP*GP*(XAM)P*UP*AP*CP*C)-3') | Authors: | Ennifar, E, Micura, R. | Deposit date: | 2022-01-14 | Release date: | 2023-01-25 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Towards a comprehensive understanding of RNA deamination: synthesis and properties of xanthosine-modified RNA. Nucleic Acids Res., 50, 2022
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7QUA
| Duplex RNA containing Xanthosine-Cytosine base pairs | Descriptor: | MAGNESIUM ION, RNA (5'-R(*CP*GP*CP*GP*(XAN)P*AP*UP*UP*AP*GP*CP*G)-3'), SODIUM ION | Authors: | Ennifar, E, Micura, R. | Deposit date: | 2022-01-17 | Release date: | 2023-01-25 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1 Å) | Cite: | Towards a comprehensive understanding of RNA deamination: synthesis and properties of xanthosine-modified RNA. Nucleic Acids Res., 50, 2022
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4Y27
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5MRX
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3ISN
| Crystal structure of HIV-1 RT bound to A 6-vinylpyrimidine inhibitor | Descriptor: | 6-ethenyl-N,N-dimethyl-2-(methylsulfonyl)pyrimidin-4-amine, Reverse transcriptase/ribonuclease H, p51 RT | Authors: | Ennifar, E, Freisz, S, Bec, G, Dumas, P, Botta, M, Radi, M. | Deposit date: | 2009-08-26 | Release date: | 2010-03-16 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal Structure of HIV-1 Reverse Transcriptase Bound to a Non-Nucleoside Inhibitor with a Novel Mechanism of Action Angew.Chem.Int.Ed.Engl., 49, 2010
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4NXH
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1F7Y
| THE CRYSTAL STRUCTURE OF TWO UUCG LOOPS HIGHLIGHTS THE ROLE PLAYED BY 2'-HYDROXYL GROUPS IN ITS UNUSUAL STABILITY | Descriptor: | 16S RIBOSOMAL RNA FRAGMENT, 30S RIBOSOMAL PROTEIN S15, MAGNESIUM ION, ... | Authors: | Ennifar, E, Nikouline, A, Serganov, A, Tishchenko, S, Nevskaya, N, Garber, M, Ehresmann, B, Ehresmann, C, Nikonov, S, Dumas, P. | Deposit date: | 2000-06-28 | Release date: | 2000-11-22 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | The crystal structure of UUCG tetraloop. J.Mol.Biol., 304, 2000
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6Y0T
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6Y0Y
| Sarcin Ricin Loop, mutant C2666U | Descriptor: | MAGNESIUM ION, RNA (27-MER), SODIUM ION | Authors: | Ennifar, E, Westhof, E. | Deposit date: | 2020-02-10 | Release date: | 2021-02-17 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (0.95 Å) | Cite: | Sarcin Ricin Loop, mutant C2666U To Be Published
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3S8U
| Crystal structure of a 2-azido-adenine-modified RNA | Descriptor: | Ecoli 23 S rRNA Sarcin Ricin loop | Authors: | Ennifar, E, Micura, R. | Deposit date: | 2011-05-31 | Release date: | 2012-04-11 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | 2'-Azido RNA, a Versatile Tool for Chemical Biology: Synthesis, X-ray Structure, siRNA Applications, Click Labeling. Acs Chem.Biol., 7, 2012
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3S7C
| Crystal structure of a 2'-azido-uridine-modified RNA | Descriptor: | Ecoli 23 S rRNA Sarcin Ricin loop | Authors: | Ennifar, E, Micura, R. | Deposit date: | 2011-05-26 | Release date: | 2012-04-11 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | 2'-Azido RNA, a Versatile Tool for Chemical Biology: Synthesis, X-ray Structure, siRNA Applications, Click Labeling. Acs Chem.Biol., 7, 2012
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6XUR
| RNA dodecamer with a 6-hydrazino-2-aminopurine modified base | Descriptor: | MAGNESIUM ION, RNA dodecamer with a 6-hydrazino-2-aminopurine modified base | Authors: | Ennifar, E, Micura, R, Gasser, C, Brillet, K. | Deposit date: | 2020-01-21 | Release date: | 2020-02-19 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Thioguanosine Conversion Enables mRNA-Lifetime Evaluation by RNA Sequencing Using Double Metabolic Labeling (TUC-seq DUAL). Angew.Chem.Int.Ed.Engl., 59, 2020
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6XUS
| RNA dodecamer with a 6-hydrazino-2-aminopurine modified base | Descriptor: | MAGNESIUM ION, RNA dodecamer with a 6-hydrazino-2-aminopurine modified base, SODIUM ION | Authors: | Ennifar, E, Micura, R, Gasser, C, Brillet, K. | Deposit date: | 2020-01-21 | Release date: | 2021-02-03 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Thioguanosine Conversion Enables mRNA-Lifetime Evaluation by RNA Sequencing Using Double Metabolic Labeling (TUC-seq DUAL). Angew.Chem.Int.Ed.Engl., 59, 2020
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462D
| CRYSTAL STRUCTURE OF THE HIV-1 GENOMIC RNA DIMERIZATION INITIATION SITE | Descriptor: | MAGNESIUM ION, RNA (5'-R(*CP*UP*UP*GP*CP*UP*GP*AP*GP*GP*UP*GP*CP*AP*CP*AP*CP*AP*GP*CP*AP*AP*G) -3') | Authors: | Ennifar, E, Yusupov, M, Walter, P, Marquet, R, Ehresmann, C, Ehresmann, B, Dumas, P. | Deposit date: | 1999-03-18 | Release date: | 1999-12-02 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The crystal structure of the dimerization initiation site of genomic HIV-1 RNA reveals an extended duplex with two adenine bulges. Structure Fold.Des., 7, 1999
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6ZYB
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6ZXZ
| Sarcin-Ricin Loop RNA from Ecoli with a A2670-2'-OCF3 modification | Descriptor: | POTASSIUM ION, SODIUM ION, Sarcin-Ricin Loop RNA from Ecoli with a A2670-2'-OCF3 modification | Authors: | Ennifar, E. | Deposit date: | 2020-07-30 | Release date: | 2020-12-16 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.44 Å) | Cite: | 2'- O -Trifluoromethylated RNA - a powerful modification for RNA chemistry and NMR spectroscopy. Chem Sci, 11, 2020
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1K9W
| HIV-1(MAL) RNA Dimerization Initiation Site | Descriptor: | HIV-1 DIS(Mal)UU RNA, MAGNESIUM ION | Authors: | Ennifar, E, Walter, P, Ehresmann, B, Ehresmann, C, Dumas, P. | Deposit date: | 2001-10-31 | Release date: | 2001-11-30 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Crystal structures of coaxially stacked kissing complexes of the HIV-1 RNA dimerization initiation site. Nat.Struct.Biol., 8, 2001
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5NQI
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4NMG
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4NLF
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1ZCI
| HIV-1 DIS RNA subtype F- monoclinic form | Descriptor: | 5'-R(*CP*(5BU)P*UP*GP*CP*UP*GP*AP*AP*GP*UP*GP*CP*AP*CP*AP*CP*AP*GP*CP*AP*AP*G)-3', POTASSIUM ION | Authors: | Ennifar, E, Dumas, P. | Deposit date: | 2005-04-12 | Release date: | 2006-01-31 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Polymorphism of Bulged-out Residues in HIV-1 RNA DIS Kissing Complex and Structure Comparison with Solution Studies. J.Mol.Biol., 356, 2006
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1YXP
| HIV-1 DIS RNA subtype F- Zn soaked | Descriptor: | 5'-R(*CP*UP*(5BU)P*GP*CP*UP*GP*AP*AP*GP*UP*GP*CP*AP*CP*AP*CP*AP*GP*CP*AP*AP*G)-3', ZINC ION | Authors: | Ennifar, E, Dumas, P. | Deposit date: | 2005-02-22 | Release date: | 2006-01-31 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Polymorphism of Bulged-out Residues in HIV-1 RNA DIS Kissing Complex and Structure Comparison with Solution Studies. J.Mol.Biol., 356, 2006
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