6BL4
| Crystal Complex of Cyclooxygenase-2 with indomethacin-ethylenediamine-dansyl conjugate | 分子名称: | 2-[1-(4-chlorobenzene-1-carbonyl)-5-methoxy-2-methyl-1H-indol-3-yl]-N-[2-({[5-(dimethylamino)naphthalen-1-yl]sulfonyl}amino)ethyl]acetamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Xu, S, Uddin, M.J, Banerjee, S, Marnett, L.J. | 登録日 | 2017-11-09 | 公開日 | 2018-11-14 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | 主引用文献 | Fluorescent indomethacin-dansyl conjugates utilize the membrane-binding domain of cyclooxygenase-2 to block the opening to the active site. J.Biol.Chem., 294, 2019
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7VYU
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6UI9
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4Z0L
| The murine cyclooxygenase-2 complexed with a nido-dicarbaborate-containing indomethacin derivative | 分子名称: | (R)-7-{[5-methoxy-2-methyl-3-(methoxycarbonylmethyl)-1H-indolyl]carbonyl}-7,8-dicarba-nido-dodeca-hydroundecaborate, (S)-7-{[5-methoxy-2-methyl-3-(methoxycarbonylmethyl)-1H-indolyl]carbonyl}-7,8-dicarba-nido-dodeca-hydroundecaborate, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Xu, S, Neumann, W, Banerjee, S, Hey-Hawkins, E, Marnett, L.J. | 登録日 | 2015-03-26 | 公開日 | 2015-06-10 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | nido-Dicarbaborate Induces Potent and Selective Inhibition of Cyclooxygenase-2. Chemmedchem, 11, 2016
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6UV5
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7VDV
| The overall structure of human chromatin remodeling PBAF-nucleosome complex | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, AT-rich interactive domain-containing protein 2,AT-rich interactive domain-containing protein 2, Actin, ... | 著者 | Chen, Z.C, Chen, K.J, Yuan, J.J. | 登録日 | 2021-09-07 | 公開日 | 2022-05-18 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structure of human chromatin-remodelling PBAF complex bound to a nucleosome. Nature, 605, 2022
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4RFL
| Crystal structure of G1PDH with NADPH from Methanocaldococcus jannaschii | 分子名称: | 1,2-ETHANEDIOL, Glycerol-1-phosphate dehydrogenase [NAD(P)+], NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Carbone, V, Ronimus, R.S, Schofield, L.R, Sutherland-Smith, A.J. | 登録日 | 2014-09-26 | 公開日 | 2015-07-22 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure and Evolution of the Archaeal Lipid Synthesis Enzyme sn-Glycerol-1-phosphate Dehydrogenase. J.Biol.Chem., 290, 2015
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4RGQ
| Crystal structure of the Methanocaldococcus jannaschii G1PDH with NADPH and DHAP | 分子名称: | 1,2-ETHANEDIOL, 1,3-DIHYDROXYACETONEPHOSPHATE, Glycerol-1-phosphate dehydrogenase, ... | 著者 | Carbone, V, Ronimus, R.S, Schofield, L.R, Sutherland-Smith, A.J. | 登録日 | 2014-09-30 | 公開日 | 2015-07-22 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | 主引用文献 | Structure and Evolution of the Archaeal Lipid Synthesis Enzyme sn-Glycerol-1-phosphate Dehydrogenase. J.Biol.Chem., 290, 2015
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4RGV
| Crystal structure of the Methanocaldococcus jannaschii G1PDH | 分子名称: | Glycerol-1-phosphate dehydrogenase, MAGNESIUM ION, ZINC ION | 著者 | Carbone, V, Ronimus, R.S, Schofield, L.R, Sutherland-Smith, A.J. | 登録日 | 2014-09-30 | 公開日 | 2015-07-22 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Structure and Evolution of the Archaeal Lipid Synthesis Enzyme sn-Glycerol-1-phosphate Dehydrogenase. J.Biol.Chem., 290, 2015
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8TIM
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4HC6
| Mycobacterium tuberculosis Rv2523cE77A x-ray structure solved with 1.8 angstrom resolution | 分子名称: | BROMIDE ION, CHLORIDE ION, GLYCEROL, ... | 著者 | Kim, H.-B, Han, G.-W, Hung, L.-W, Terwilliger, C.T, Kim, C.-Y, Integrated Center for Structure and Function Innovation (ISFI) | 登録日 | 2012-09-28 | 公開日 | 2012-11-28 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Mycobacterium tuberculosis Rv2523cE77A x-ray structure solved with 1.8 angstrom resolution To be Published
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4M11
| Crystal Structure of Murine Cyclooxygenase-2 Complex with Meloxicam | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-hydroxy-2-methyl-N-(5-methyl-1,3-thiazol-2-yl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide, ... | 著者 | Xu, S, Banerjee, S, Hermanson, D.J, Marnett, L.J. | 登録日 | 2013-08-02 | 公開日 | 2014-01-22 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Oxicams Bind in a Novel Mode to the Cyclooxygenase Active Site via a Two-water-mediated H-bonding Network. J.Biol.Chem., 289, 2014
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4M10
| Crystal Structure of Murine Cyclooxygenase-2 Complex with Isoxicam | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-hydroxy-2-methyl-N-(5-methyl-1,2-oxazol-3-yl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide, ... | 著者 | Xu, S, Hermanson, D.J, Banerjee, S, Ghebreelasie, K, Marnett, L.J. | 登録日 | 2013-08-02 | 公開日 | 2014-01-22 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Oxicams Bind in a Novel Mode to the Cyclooxygenase Active Site via a Two-water-mediated H-bonding Network. J.Biol.Chem., 289, 2014
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8PK9
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8PK8
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8PKA
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6B2U
| Crystal structure of Xanthomonas campestris OleA H285N with Cerulenin | 分子名称: | (2S, 3R)-3-HYDROXY-4-OXO-7,10-TRANS,TRANS-DODECADIENAMIDE, 3-oxoacyl-[ACP] synthase III, ... | 著者 | Jensen, M.R, Goblirsch, B.R, Esler, M.A, Christenson, J.K, Mohamed, F.A, Wackett, L.P, Wilmot, C.M. | 登録日 | 2017-09-20 | 公開日 | 2018-02-28 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | The role of OleA His285 in substrate coordination of long-chain acyl-CoA To be published
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6ET1
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6ESZ
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1XX4
| Crystal Structure of Rat Mitochondrial 3,2-Enoyl-CoA | 分子名称: | 3,2-trans-enoyl-CoA isomerase, mitochondrial, BENZAMIDINE, ... | 著者 | Hubbard, P.A, Yu, W, Schulz, H, Kim, J.-J. | 登録日 | 2004-11-03 | 公開日 | 2004-11-23 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Domain swapping in the low-similarity isomerase/hydratase superfamily: the crystal structure of rat mitochondrial Delta3, Delta2-enoyl-CoA isomerase. Protein Sci., 14, 2005
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6ET0
| Crystal structure of PqsBC (C129A) mutant from Pseudomonas aeruginosa (crystal form 1) | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, ... | 著者 | Witzgall, F, Blankenfeldt, W. | 登録日 | 2017-10-25 | 公開日 | 2018-07-04 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | 主引用文献 | The Alkylquinolone Repertoire of Pseudomonas aeruginosa is Linked to Structural Flexibility of the FabH-like 2-Heptyl-3-hydroxy-4(1H)-quinolone (PQS) Biosynthesis Enzyme PqsBC. Chembiochem, 19, 2018
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6ET3
| Crystal structure of PqsBC (C129S) mutant from Pseudomonas aeruginosa (crystal form 4) | 分子名称: | (R,R)-2,3-BUTANEDIOL, PqsB, PqsC, ... | 著者 | Witzgall, F, Blankenfeldt, W. | 登録日 | 2017-10-25 | 公開日 | 2018-07-04 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | The Alkylquinolone Repertoire of Pseudomonas aeruginosa is Linked to Structural Flexibility of the FabH-like 2-Heptyl-3-hydroxy-4(1H)-quinolone (PQS) Biosynthesis Enzyme PqsBC. Chembiochem, 19, 2018
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1T8K
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4A0S
| STRUCTURE OF THE 2-OCTENOYL-COA CARBOXYLASE REDUCTASE CINF IN COMPLEX WITH NADP AND 2-OCTENOYL-COA | 分子名称: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, OCTANOYL-COENZYME A, OCTENOYL-COA REDUCTASE/CARBOXYLASE | 著者 | Quade, N, Huo, L, Rachid, S, Heinz, D.W, Muller, R. | 登録日 | 2011-09-12 | 公開日 | 2011-12-07 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Unusual carbon fixation gives rise to diverse polyketide extender units. Nat. Chem. Biol., 8, 2011
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4A10
| Apo-structure of 2-octenoyl-CoA carboxylase reductase CinF from streptomyces sp. | 分子名称: | OCTENOYL-COA REDUCTASE/CARBOXYLASE | 著者 | Quade, N, Huo, L, Rachid, S, Heinz, D.W, Muller, R. | 登録日 | 2011-09-13 | 公開日 | 2011-12-07 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Unusual Carbon Fixation Giving Rise to Diverse Polyketide Extender Units Nat.Chem.Biol., 8, 2011
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