8PK8

Structure of the human mitochondrial iron-sulfur cluster biosynthesis complex during persulfide transfer (persulfide on ISCU2)

Summary for 8PK8

Entry DOI	10.2210/pdb8pk8/pdb
EMDB information	17732
Descriptor	Cysteine desulfurase, LYR motif-containing protein 4, Acyl carrier protein, ... (9 entities in total)
Functional Keywords	cysteine desulfurase, fes biosynthesis, fes biogenesis, mitochondria, friedreich's ataxia, persulfide, frataxin, transferase
Biological source	Homo sapiens (human) More
Total number of polymer chains	5
Total formula weight	98200.09
Authors	Steinhilper, R.,Murphy, B.J. (deposition date: 2023-06-26, release date: 2024-05-01)
Primary citation	Schulz, V.,Steinhilper, R.,Oltmanns, J.,Freibert, S.A.,Krapoth, N.,Linne, U.,Welsch, S.,Hoock, M.H.,Schunemann, V.,Murphy, B.J.,Lill, R. Mechanism and structural dynamics of sulfur transfer during de novo [2Fe-2S] cluster assembly on ISCU2. Nat Commun, 15:3269-3269, 2024 Cited by PubMed: 38627381 DOI: 10.1038/s41467-024-47310-8 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.49 Å)

Structure validation