PDB: 222624 件ウェブページステータス検索Chemie searchBIRD

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4UXQ	FGFR4 in complex with Ponatinib 分子名称: 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzam ide, FIBROBLAST GROWTH FACTOR RECEPTOR 4, SULFATE ION 著者 Tucker, J, Klein, T, Breed, J, Breeze, A, Overman, R, Phillips, C, Norman, R.A. 登録日 2014-08-27 公開日 2014-12-03 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structural Insights Into Fgfr Kinase Isoform Selectivity: Diverse Binding Modes of Azd4547 and Ponatinib in Complex with Fgfr1 and Fgfr4 Structure, 22, 2014
4UU6	CRYSTAL STRUCTURE OF THE PDZ DOMAIN OF PALS1 分子名称: ACETATE ION, CHLORIDE ION, GLYCEROL, ... 著者 Ivanova, M.E, Purkiss, A.G, McDonald, N.Q. 登録日 2014-07-24 公開日 2015-01-14 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structures of the human Pals1 PDZ domain with and without ligand suggest gated access of Crb to the PDZ peptide-binding groove. Acta Crystallogr. D Biol. Crystallogr., 71, 2015
4UVK	Cohesin subunit Scc3 from Z. rouxii, 88-1035 分子名称: ZYRO0D15994P 著者 Roig, M.B, Nasmyth, K, Lowe, J. 登録日 2014-08-06 公開日 2014-08-20 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structure and Function of Cohesins Scc3/Sa Regulatory Subunit FEBS Lett., 588, 2014
7YPL	Crystal structure of fibronectin type III domain variant, a VEGFR2-specific antagonist 分子名称: Fibronectin, SULFATE ION 著者 Chang, Y.T, Chen, C.Y, Chuang, W.J. 登録日 2022-08-03 公開日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 A Novel Disulfide Bond Engineering of Fibronectin Type III Domain Enhances Thermostability and Solubility of VEGFR2-Specific Antagonist To Be Published
7YRV	Solution structures of a disulfide-directed multicyclic peptide with affinity for FGFR1 分子名称: LF1 著者 Fan, S.H, Wu, C.L. 登録日 2022-08-10 公開日 2023-08-16 実験手法 SOLUTION NMR 主引用文献 Disulfide-Directed Multicyclic Peptide Libraries for the Discovery of Pep-tide Ligands and Drugs To Be Published
4UZR	Crystal Structure of Pyrococcus horikoshii Ph1500 分子名称: PUTATIVE UNCHARACTERIZED PROTEIN PH1500 著者 Hartmann, M.D, Ammelburg, M, Djuranovic, S, Lupas, A.N. 登録日 2014-09-08 公開日 2015-10-07 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.652 Å) 主引用文献 Crystal Structure of Pyrococcus Horikoshii Ph1500 To be Published
6ES8	HIV capsid hexamer with IP6 ligand 分子名称: Gag protein, INOSITOL HEXAKISPHOSPHATE 著者 James, L.C. 登録日 2017-10-19 公開日 2018-08-15 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 IP6 is an HIV pocket factor that prevents capsid collapse and promotes DNA synthesis. Elife, 7, 2018
4UR0	Crystal structure of the PCE reductive dehalogenase from S. multivorans in complex with trichloroethene 分子名称: 1,1,2-trichloroethene, BENZAMIDINE, GLYCEROL, ... 著者 Bommer, M, Kunze, C, Fesseler, J, Schubert, T, Diekert, G, Dobbek, H. 登録日 2014-06-25 公開日 2014-10-15 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.798 Å) 主引用文献 Structural Basis for Organohalide Respiration. Science, 346, 2014
4UWJ	Crystal structure of Aspergillus fumigatus N-myristoyl transferase in complex with myristoyl CoA and a capped pyrazole sulphonamide ligand 分子名称: 2,6-dichloro-N-(difluoromethyl)-4-[3-(piperidin-4-yl)propyl]-N-(1,3,5-trimethyl-1H-pyrazol-4-yl)benzenesulfonamide, GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE, TETRADECANOYL-COA 著者 Robinson, D.A, Brand, S, Norcross, N.R, Thompson, S, Harrison, J.R, Smith, V.C, Torrie, L.S, McElroy, S.P, Hallyburton, I, Norval, S, Stojanovski, L, Simeons, F.R.C, Frearson, J.A, Brenk, R, Fairlamb, A.H, Ferguson, M.A.J, Wyatt, P.G, Gilbert, I.H, Read, K.D. 登録日 2014-08-12 公開日 2014-12-03 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Lead optimization of a pyrazole sulfonamide series of Trypanosoma brucei N-myristoyltransferase inhibitors: identification and evaluation of CNS penetrant compounds as potential treatments for stage 2 human African trypanosomiasis. J. Med. Chem., 57, 2014
4UTI	XenA - oxidized - Y183F variant in complex with coumarin 分子名称: COUMARIN, FLAVIN MONONUCLEOTIDE, NADH:flavin oxidoreductase, ... 著者 Werther, T, Dobbek, H. 登録日 2014-07-21 公開日 2015-08-05 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.099 Å) 主引用文献 Redox-dependent substrate-cofactor interactions in the Michaelis-complex of a flavin-dependent oxidoreductase Nat Commun, 8, 2017
7YSS	Novel salt-resistant antimicrobial peptide, RR14 分子名称: RR14 著者 Lin, T.L, Tseng, T.S, Fan, P.J. 登録日 2022-08-13 公開日 2023-08-16 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Novel salt-resistant antimicrobial peptide, RR14 To Be Published
4UYG	C-Terminal bromodomain of Human BRD2 with I-BET726 (GSK1324726A) 分子名称: 4-[(2S,4R)-1-acetyl-4-[(4-chlorophenyl)amino]-2-methyl-1,2,3,4-tetrahydroquinolin-6-yl]benzoic acid, BROMODOMAIN-CONTAINING PROTEIN 2, SULFATE ION 著者 Chung, C, Bamborough, P, Gosmini, R. 登録日 2014-08-31 公開日 2014-10-08 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The Discovery of I-Bet726 (Gsk1324726A), a Potent Tetrahydroquinoline Apoa1 Up-Regulator and Selective Bet Bromodomain Inhibitor. J.Med.Chem., 57, 2014
4UVJ	Cohesin subunit Scc3 from yeast, 674-1072 分子名称: COHESIN SUBUNIT SCC3 著者 Roig, M.B, Nasmyth, K, Lowe, J. 登録日 2014-08-06 公開日 2014-08-20 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure and Function of Cohesins Scc3/Sa Regulatory Subunit FEBS Lett., 588, 2014
4UZ2	Crystal structure of the N-terminal LysM domains from the putative NlpC/P60 D,L endopeptidase from T. thermophilus 分子名称: CELL WALL-BINDING ENDOPEPTIDASE-RELATED PROTEIN 著者 Wong, J.E.M.M, Blaise, M. 登録日 2014-09-04 公開日 2015-01-14 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 An Intermolecular Binding Mechanism Involving Multiple Lysm Domains Mediates Carbohydrate Recognition by an Endopeptidase. Acta Crystallogr.,Sect.D, 71, 2015
7YRW	Solution structures of a disulfide-directed multicyclic peptide with affinity for HER2 分子名称: LH2 著者 Fan, S.H, Wu, C.L. 登録日 2022-08-10 公開日 2023-08-16 実験手法 SOLUTION NMR 主引用文献 Disulfide-Directed Multicyclic Peptide Libraries for the Discovery of Pep-tide Ligands and Drugs To Be Published
4V01	FGFR1 in complex with ponatinib (co-crystallisation). 分子名称: 1,2-ETHANEDIOL, 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzam ide, FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, ... 著者 Tucker, J, Klein, T, Breed, J, Breeze, A, Overman, R, Phillips, C, Norman, R.A. 登録日 2014-09-10 公開日 2014-12-10 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.33 Å) 主引用文献 Structural Insights Into Fgfr Kinase Isoform Selectivity: Diverse Binding Modes of Azd4547 and Ponatinib in Complex with Fgfr1 and Fgfr4 Structure, 22, 2014
6E8M	Legionella Longbeachae LeSH (Llo2327) bound to the human DnaJ-A1 pTyr381 peptide 分子名称: DnaJ-A1 pTyr381 peptide, LeSH (Llo2327) 著者 Kaneko, T, Li, S.S.C. 登録日 2018-07-30 公開日 2018-11-14 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.61 Å) 主引用文献 Identification and characterization of a large family of superbinding bacterial SH2 domains. Nat Commun, 9, 2018
4V36	The structure of L-PGS from Bacillus licheniformis 分子名称: 2,6-DIAMINO-HEXANOIC ACID AMIDE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, LYSYL-TRNA-DEPENDENT L-YSYL-PHOSPHATIDYLGYCEROL SYNTHASE 著者 Krausze, J, Hebecker, S, Heinz, D.W, Moser, J. 登録日 2014-10-16 公開日 2015-08-19 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structures of Two Bacterial Resistance Factors Mediating tRNA-Dependent Aminoacylation of Phosphatidylglycerol with Lysine or Alanine. Proc.Natl.Acad.Sci.USA, 112, 2015
4UZY	Crystal structure of the Chlamydomonas IFT70 and IFT52 complex 分子名称: CITRATE ANION, FLAGELLAR ASSOCIATED PROTEIN, INTRAFLAGELLAR TRANSPORT PROTEIN IFT52, ... 著者 Taschner, M, Lorentzen, E. 登録日 2014-09-09 公開日 2014-11-05 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.477 Å) 主引用文献 Crystal Structures of Ift70/52 and Ift52/46 Provide Insight Into Intraflagellar Transport B Core Complex Assembly. J.Cell Biol., 207, 2014
6E5U	Crystal structure of the mRNA export receptor NXF1/NXT1 in complex with influenza virus NS1 protein 分子名称: NTF2-related export protein 1, Non-structural protein 1, Nuclear RNA export factor 1 著者 Xie, Y, Ren, Y. 登録日 2018-07-23 公開日 2019-04-24 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.8 Å) 主引用文献 Structural basis for influenza virus NS1 protein block of mRNA nuclear export. Nat Microbiol, 4, 2019
4V23	RSV Matrix protein 分子名称: MATRIX PROTEIN, POTASSIUM ION 著者 Forster, A, Maertens, G, Bajorek, M. 登録日 2014-10-05 公開日 2015-02-25 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Dimerization of Matrix Protein is Required for Budding of Respiratory Syncytial Virus. J.Virol., 89, 2015
7YRE	Crystal structure of a bright green fluorescent protein (StayGold) with triple mutations (N137A, Q140S, Y187F) in jellyfish Cytaeis uchidae from Biortus 分子名称: 1,2-ETHANEDIOL, staygold(N137A,Q140S,Y187F) 著者 Wu, J, Wang, F, Gui, W, Cheng, W, Yang, Y. 登録日 2022-08-09 公開日 2023-08-16 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of a bright green fluorescent protein (StayGold) with triple mutations (N137A, Q140S, Y187F) in jellyfish Cytaeis uchidae from Biortus To Be Published
4V05	FGFR1 in complex with AZD4547. 分子名称: 1,2-ETHANEDIOL, FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME), ... 著者 Tucker, J, Klein, T, Breed, J, Breeze, A, Overman, R, Phillips, C, Norman, R.A. 登録日 2014-09-10 公開日 2014-12-10 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.57 Å) 主引用文献 Structural Insights Into Fgfr Kinase Isoform Selectivity: Diverse Binding Modes of Azd4547 and Ponatinib in Complex with Fgfr1 and Fgfr4 Structure, 22, 2014
4V3L	RNF38-UB-UbcH5B-Ub complex 分子名称: 1,2-ETHANEDIOL, E3 UBIQUITIN-PROTEIN LIGASE RNF38, POLYUBIQUITIN-C, ... 著者 Buetow, L, Gabrielsen, M, Anthony, N.G, Dou, H, Patel, A, Aitkenhead, H, Sibbet, G.J, Smith, B.O, Huang, D.T. 登録日 2014-10-20 公開日 2015-04-08 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 Activation of a Primed Ring E3-E2-Ubiquitin Complex by Non-Covalent Ubiquitin. Mol.Cell, 58, 2015
6E97	Crystal structure of the aryl acid adenylating enzyme FscC from Fuscachelin NRPS in complex with DHB-adenylate 分子名称: 2,3-dihydroxybenzoate-AMP ligase, 5'-O-[(S)-[(2,3-dihydroxybenzene-1-carbonyl)oxy](hydroxy)phosphoryl]adenosine, GLYCEROL, ... 著者 Bruner, S.D, Zagulyaeva, A.A. 登録日 2018-07-31 公開日 2019-08-21 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Implication of MbtH-like proteins in crystallization of the independent NRPS A domains. Crystal structure of FscC: supporting rationale for revised mechanism of freestanding aryl acid adenylating enzymes To Be Published

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