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2MHF
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Solution structure of the cyclic-nucleotide binding homology domain of a KCNH channel
分子名称: Uncharacterized protein
著者Li, Q, Ng, H.
登録日2013-11-21
公開日2014-04-02
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution structure of the cyclic-nucleotide binding homology domain of a KCNH channel.
J.Struct.Biol., 186, 2014
2M99
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Solution structure of a chymotrypsin inhibitor from the Taiwan cobra
分子名称: Protease inhibitor NACI
著者Lin, Y.-J, Ikeya, T, Guntert, P, Chang, L.-S.
登録日2013-06-05
公開日2013-10-16
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献NMR solution structure of a Chymotrypsin inhibitor from the Taiwan cobra Naja naja atra.
Molecules, 18, 2013
2MEE
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CONTRIBUTION OF HYDROPHOBIC EFFECT TO THE CONFORMATIONAL STABILITY OF HUMAN LYSOZYME
分子名称: LYSOZYME, SODIUM ION
著者Takano, K, Yamagata, Y, Yutani, K.
登録日1998-05-02
公開日1998-07-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Contribution of amino acid substitutions at two different interior positions to the conformational stability of human lysozyme
Protein Eng., 12, 1999
2LZ2
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BU of 2lz2 by Molmil
THE THREE DIMENSIONAL STRUCTURE OF TURKEY EGG WHITE LYSOZYME AT 2.2 ANGSTROMS RESOLUTION
分子名称: TURKEY EGG WHITE LYSOZYME
著者Parsons, M.R, Phillips, S.E.V.
登録日1988-10-20
公開日1989-10-15
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The Three Dimensional Structure of Turkey Egg White Lysozyme at 2.2 Angstroms Resolution
To be Published
2LYV
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Solution structure of the two RRM domains of hnRNP A1 (UP1) using segmental isotope labeling
分子名称: Heterogeneous nuclear ribonucleoprotein A1
著者Barraud, P, Allain, F.H.-T.
登録日2012-09-19
公開日2012-12-26
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution structure of the two RNA recognition motifs of hnRNP A1 using segmental isotope labeling: how the relative orientation between RRMs influences the nucleic acid binding topology.
J.Biomol.Nmr, 55, 2013
2JDG
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BU of 2jdg by Molmil
Affilin based on HUMAN GAMMA-B CRYSTALLIN
分子名称: GAMMA CRYSTALLIN B
著者Ebersbach, H, Fiedler, E, Scheuermann, T, Fiedler, M, Stubbs, M.T, Reimann, C, Proetzel, G, Rudolph, R, Fiedler, U.
登録日2007-01-08
公開日2007-07-24
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Affilin-Novel Binding Molecules Based on Human Gamma-B-Crystallin, an All Beta-Sheet Protein.
J.Mol.Biol., 372, 2007
2PG7
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BU of 2pg7 by Molmil
Crystal Structure of Human Microsomal P450 2A6 N297Q/I300V
分子名称: Cytochrome P450 2A6, PROTOPORPHYRIN IX CONTAINING FE
著者Sansen, S, Hsu, M.H, Stout, C.D, Johnson, E.F.
登録日2007-04-06
公開日2007-07-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural insight into the altered substrate specificity of human cytochrome P450 2A6 mutants.
Arch.Biochem.Biophys., 464, 2007
2PH8
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Crystal Structure of Human Beta Secretase Complexed with inhibitor
分子名称: Beta-secretase 1, N-[(5R,14R)-5-AMINO-5,14-DIMETHYL-4-OXO-3-OXA-18-AZATRICYCLO[15.3.1.1~7,11~]DOCOSA-1(21),7(22),8,10,17,19-HEXAEN-19-YL]-N-METHYLMETHANESULFONAMIDE, SULFATE ION
著者Munshi, S.
登録日2007-04-10
公開日2008-04-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Strategies toward improving the brain penetration of macrocyclic tertiary carbinamine BACE-1 inhibitors.
Bioorg.Med.Chem.Lett., 17, 2007
2JP9
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Structure of the Wilms Tumor Suppressor Protein Zinc Finger Domain Bound to DNA
分子名称: DNA (5'-D(P*DCP*DGP*DCP*DGP*DGP*DGP*DGP*DGP*DCP*DGP*DTP*DCP*DTP*DGP*DCP*DGP*DC)-3'), DNA (5'-D(P*DGP*DCP*DGP*DCP*DAP*DGP*DAP*DCP*DGP*DCP*DCP*DCP*DCP*DCP*DGP*DCP*DG)-3'), Wilms tumor 1, ...
著者Stoll, R, Lee, B.M, Debler, E.W, Laity, J.H, Wilson, I.A, Dyson, H.J, Wright, P.E.
登録日2007-04-30
公開日2007-10-30
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Structure of the wilms tumor suppressor protein zinc finger domain bound to DNA
J.Mol.Biol., 372, 2007
2K01
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Structure of a locked SDF1 dimer
分子名称: Stromal cell-derived factor 1
著者Volkman, B.F, Veldkamp, C.T, Peterson, F.C.
登録日2008-01-23
公開日2008-10-28
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structural basis of CXCR4 sulfotyrosine recognition by the chemokine SDF-1/CXCL12
Sci.Signal., 1, 2008
2K2M
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BU of 2k2m by Molmil
Structural Basis of PxxDY Motif Recognition in SH3 Binding
分子名称: Eps8-like protein 1
著者Aitio, O, Hellman, M, Kesti, T, Kleino, I, Samuilova, O, Tossavainen, H, Saksela, K, Permi, P.
登録日2008-04-02
公開日2009-02-17
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Structural basis of PxxDY motif recognition in SH3 binding.
J.Mol.Biol., 382, 2008
2JX2
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Solution conformation of RNA-bound NELF-E RRM
分子名称: Negative elongation factor E
著者Jampani, N, Schweimer, K, Wenzel, S, Woehrl, B.M, Roesch, P.
登録日2007-11-02
公開日2008-04-08
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献NELF-E RRM Undergoes Major Structural Changes in Flexible Protein Regions on Target RNA Binding
Biochemistry, 47, 2008
2K4D
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E2-c-Cbl recognition is necessary but not sufficient for ubiquitination activity
分子名称: E3 ubiquitin-protein ligase CBL, ZINC ION
著者Huang, A, De Jong, R.N, Wienk, H, Winkler, S.G, Timmers, H.T.M, Boelens, R.
登録日2008-06-06
公開日2009-01-20
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献E2-c-Cbl recognition is necessary but not sufficient for ubiquitination activity
J.Mol.Biol., 385, 2009
2JJJ
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Endothiapepsin in complex with a gem-diol inhibitor.
分子名称: ENDOTHIAPEPSIN, N~2~-[(2R)-2-benzyl-3-(tert-butylsulfonyl)propanoyl]-N-{(1R)-1-(cyclohexylmethyl)-3,3-difluoro-2,2-dihydroxy-4-[(2-morpholin-4-ylethyl)amino]-4-oxobutyl}-3-(1H-imidazol-3-ium-4-yl)-L-alaninamide, SULFATE ION
著者Coates, L, Tuan, H.-F, Tomanicek, S.J, Kovalevsky, A, Mustyakimov, M, Erskine, P, Cooper, J.
登録日2008-04-09
公開日2008-05-27
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献The Catalytic Mechanism of an Aspartic Proteinase Explored with Neutron and X-Ray Diffraction
J.Am.Chem.Soc., 130, 2008
2JJI
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BU of 2jji by Molmil
Endothiapepsin in complex with a gem-diol inhibitor.
分子名称: ENDOTHIAPEPSIN, N~2~-[(2R)-2-benzyl-3-(tert-butylsulfonyl)propanoyl]-N-{(1R)-1-(cyclohexylmethyl)-3,3-difluoro-2,2-dihydroxy-4-[(2-morpholin-4-ylethyl)amino]-4-oxobutyl}-3-(1H-imidazol-3-ium-4-yl)-L-alaninamide, SULFATE ION
著者Coates, L, Tuan, H.-F, Tomanicek, S.J, Kovalevsky, A, Mustyakimov, M, Erskine, P, Cooper, J.
登録日2008-04-09
公開日2008-05-27
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献The Catalytic Mechanism of an Aspartic Proteinase Explored with Neutron and X-Ray Diffraction
J.Am.Chem.Soc., 130, 2008
2JBO
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Protein kinase MK2 in complex with an inhibitor (crystal form-1, soaking)
分子名称: 2-(2-QUINOLIN-3-YLPYRIDIN-4-YL)-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE, MAP KINASE-ACTIVATED PROTEIN KINASE 2, PHOSPHATE ION
著者Hillig, R.C, Eberspaecher, U, Monteclaro, F, Huber, M, Nguyen, D, Mengel, A, Muller-Tiemann, B, Egner, U.
登録日2006-12-09
公開日2007-03-20
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural Basis for a High Affinity Inhibitor Bound to Protein Kinase Mk2.
J.Mol.Biol., 369, 2007
2HTV
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BU of 2htv by Molmil
N4 neuraminidase
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Neuraminidase
著者Russell, R.J, Haire, L.F, Stevens, D.J, Collins, P.J, Lin, Y.P, Blackburn, G.M, Hay, A.J, Gamblin, S.J, Skehel, J.J.
登録日2006-07-26
公開日2006-09-05
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
2HSO
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Multipattern rietveld refinement with protein powder data: An approach to higher resolution
分子名称: Lysozyme C
著者Von Dreele, R.B.
登録日2006-07-22
公開日2006-08-29
最終更新日2011-07-13
実験手法POWDER DIFFRACTION
主引用文献Multipattern Rietveld refinement with protein powder data: an approach to higher resolution
J.APPL.CRYSTALLOGR., 40, 2007
2HH2
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Solution structure of the fourth KH domain of KSRP
分子名称: KH-type splicing regulatory protein
著者Garcia-Mayoral, M.F.
登録日2006-06-27
公開日2007-05-08
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献The Structure of the C-Terminal KH Domains of KSRP Reveals a Noncanonical Motif Important for mRNA Degradation.
Structure, 15, 2007
2HMH
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Crystal structure of SOCS3 in complex with gp130(pTyr757) phosphopeptide.
分子名称: Interleukin-6 receptor beta chain, Suppressor of cytokine signaling 3
著者Bergamin, E, Wu, J, Hubbard, S.R.
登録日2006-07-11
公開日2006-08-15
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for phosphotyrosine recognition by suppressor of cytokine signaling-3.
Structure, 14, 2006
2Q2P
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Beta-lactoglobulin (reverse native)
分子名称: Beta-lactoglobulin
著者Vijayalakshmi, L, Krishna, R, Sankaranarayanan, R, Vijayan, M.
登録日2007-05-29
公開日2008-02-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.96 Å)
主引用文献An asymmetric dimer of beta-lactoglobulin in a low humidity crystal form-Structural changes that accompany partial dehydration and protein action.
Proteins, 71, 2007
2PLX
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Trypsin complexed to a synthetic peptide from Veronica hederifolia
分子名称: CALCIUM ION, CITRATE ANION, Cationic trypsin, ...
著者Conners, R, Brady, R.L.
登録日2007-04-20
公開日2007-08-07
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献An Unusual Helix-Turn-Helix Protease Inhibitory Motif in a Novel Trypsin Inhibitor from Seeds of Veronica (Veronica hederifolia L.)
J.Biol.Chem., 282, 2007
2HTQ
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N8 neuraminidase in complex with zanamivir
分子名称: Neuraminidase, ZANAMIVIR
著者Russell, R.J, Haire, L.F, Stevens, D.J, Collins, P.J, Lin, Y.P, Blackburn, G.M, Hay, A.J, Gamblin, S.J, Skehel, J.J.
登録日2006-07-26
公開日2006-09-05
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
2HU1
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Crystal structure Analysis of Hen Egg White Lyszoyme
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Lysozyme C, ...
著者Wine, Y, Cohen-Hadar, N, Freeman, A, Lagziel-Simis, S, Frolow, F.
登録日2006-07-26
公開日2007-05-22
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Elucidation of the mechanism and end products of glutaraldehyde crosslinking reaction by X-ray structure analysis
Biotechnol.Bioeng., 98, 2007
2HH4
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NMR structure of human insulin mutant GLY-B8-D-SER, HIS-B10-ASP PRO-B28-LYS, LYS-B29-PRO, 20 structures
分子名称: insulin A chain, insulin B chain
著者Hua, Q.X, Nakagawa, S, Hu, S.Q, Jia, W, Weiss, M.A.
登録日2006-06-27
公開日2006-07-18
最終更新日2021-10-20
実験手法SOLUTION NMR
主引用文献Toward the Active Conformation of Insulin: Stereospecific modulation of a structural switch in the B chain.
J.Biol.Chem., 281, 2006

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