PDB: 223790 件ウェブページステータス検索Chemie searchBIRD

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4J53	Crystal structure of PLK1 in complex with TAK-960 分子名称: 4-[(9-cyclopentyl-7,7-difluoro-5-methyl-6-oxo-6,7,8,9-tetrahydro-5H-pyrimido[4,5-b][1,4]diazepin-2-yl)amino]-2-fluoro-5-methoxy-N-(1-methylpiperidin-4-yl)benzamide, ACETATE ION, Serine/threonine-protein kinase PLK1, ... 著者 Hosfield, D.J, Skene, R.J. 登録日 2013-02-07 公開日 2013-05-29 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Discovery of TAK-960: An orally available small molecule inhibitor of polo-like kinase 1 (PLK1). Bioorg.Med.Chem.Lett., 23, 2013
4J5C	Human Cyclophilin D Complexed with an Inhibitor 分子名称: 1-(4-aminobenzyl)-3-[(2S)-4-(methylsulfanyl)-1-{(2R)-2-[2-(methylsulfanyl)phenyl]pyrrolidin-1-yl}-1-oxobutan-2-yl]urea, Peptidyl-prolyl cis-trans isomerase F, mitochondrial 著者 Gelin, M, Colliandre, L, Bessin, Y, Guichou, J.F. 登録日 2013-02-08 公開日 2014-02-19 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.03 Å) 主引用文献 Fragment-based discovery of a new family of non-peptidic small-molecule cyclophilin inhibitors with potent antiviral activities. Nat Commun, 7, 2016
3E9D	Structure of full-length TIGAR from Danio rerio 分子名称: PHOSPHATE ION, POTASSIUM ION, Zgc:56074 著者 Li, H, Jogl, G. 登録日 2008-08-21 公開日 2008-12-16 最終更新日 2017-10-25 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 TIGAR (TP53 induced glycolysis and apoptosis regulator) is a fructose-2,6- and fructose-1,6-bisphosphatase To be Published
4J5O	Room temperature crystal structure of a RNA binding motif protein 39 (Rbm39) from Mus musculus at 1.11 A resolution 分子名称: RNA-binding protein 39 著者 Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL) 登録日 2013-02-08 公開日 2013-04-10 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.11 Å) 主引用文献 Room temperature crystal structure of a RNA binding motif protein 39 (Rbm39) from Mus musculus at 1.11 A resolution To be published
2QF3	Structure of the delta PDZ truncation of the DegS protease 分子名称: PHOSPHATE ION, Protease degS 著者 Sohn, J, Grant, R.A, Sauer, R.T. 登録日 2007-06-26 公開日 2007-12-11 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Allosteric activation of DegS, a stress sensor PDZ protease. Cell(Cambridge,Mass.), 131, 2007
4J6M	Crystal structure of calcium2+-free wild-type CD23 lectin domain (crystal form D) 分子名称: Low affinity immunoglobulin epsilon Fc receptor, SULFATE ION 著者 Dhaliwal, B, Fabiane, S.M, Sutton, B.J. 登録日 2013-02-11 公開日 2013-08-28 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.48 Å) 主引用文献 Conformational plasticity at the IgE-binding site of the B-cell receptor CD23. Mol.Immunol., 56, 2013
2QHD	Crystal structure of ecarpholin S (ser49-PLA2) complexed with fatty acid 分子名称: LAURIC ACID, Phospholipase A2 著者 Zhou, X, Tan, T.C, Valiyaveettil, S, Go, M.L, Kini, R.M, Sivaraman, J. 登録日 2007-07-02 公開日 2007-10-16 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structural Characterization of Myotoxic Ecarpholin S from Echis carinatus Venom Biophys.J., 95, 2008
2QFZ	Crystal structure of human TBC1 domain family member 22A 分子名称: TBC1 domain family member 22A, UNKNOWN ATOM OR ION 著者 Tong, Y, Tempel, W, Dimov, S, Dong, A, Landry, R, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) 登録日 2007-06-28 公開日 2007-07-10 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of human TBC1 domain family member 22A. To be Published
4J75	Crystal Structure of a parasite tRNA synthetase, product-bound 分子名称: GLYCEROL, TRYPTOPHANYL-5'AMP, Tryptophanyl-tRNA synthetase 著者 Koh, C.Y, Kim, J.E, Verlinde, C.L.M.J, Hol, W.G.J. 登録日 2013-02-12 公開日 2013-05-22 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structures of Plasmodium falciparum cytosolic tryptophanyl-tRNA synthetase and its potential as a target for structure-guided drug design. Mol.Biochem.Parasitol., 189, 2013
2QHR	Crystal structure of the 13F6-1-2 Fab fragment bound to its Ebola virus glycoprotein peptide epitope. 分子名称: 13F6-1-2 Fab fragment V lambda x light chain, 13F6-1-2 Fab fragment heavy chain, Envelope glycoprotein peptide 著者 Lee, J.E, Kuehne, A, Abelson, D.M, Fusco, M.L, Hart, M.K, Saphire, E.O. 登録日 2007-07-02 公開日 2008-01-22 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Complex of a protective antibody with its Ebola virus GP peptide epitope: unusual features of a V lambda x light chain. J.Mol.Biol., 375, 2008
2QIA	Structural basis for the acyl chain selectivity and mechanism of UDP-N-acetylglucosamine Acyltransferase 分子名称: UDP-N-acetylglucosamine acyltransferase, uridine-5'-diphosphate-3-O-(R-3-hydroxymyristoyl)-N-acetyl-D-glucosamine 著者 Williams, A.H, Raetz, C.R.H. 登録日 2007-07-03 公開日 2007-10-02 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 Structural basis for the acyl chain selectivity and mechanism of UDP-N-acetylglucosamine acyltransferase Proc.Natl.Acad.Sci.Usa, 104, 2007
3EA8	Crystal structure of SARS-CoV main protease triple mutant STI/A in space group C2 分子名称: 3C-like proteinase 著者 Shi, J.H, Jayaraman, S, Song, J.X. 登録日 2008-08-25 公開日 2009-09-01 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Crystal structure of SARS-CoV Mpro mutant To be Published
4J8M	Aurora A in complex with CD532 分子名称: 1,2-ETHANEDIOL, 1-[4-[[4-[(5-cyclopentyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl]amino]phenyl]-3-[3-(trifluoromethyl)phenyl]urea, Aurora kinase A, ... 著者 Meyerowitz, J.G, Gustafson, W.C, Shokat, K.M, Weiss, W.A. 登録日 2013-02-14 公開日 2014-09-10 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (1.853 Å) 主引用文献 Drugging MYCN through an Allosteric Transition in Aurora Kinase A. Cancer Cell, 26, 2014
2QIR	Crystal structure of aminoglycoside acetyltransferase AAC(6')-Ib in complex whith coenzyme A and kanamycin 分子名称: (1R,2S,3S,4R,6S)-4,6-DIAMINO-3-[(3-AMINO-3-DEOXY-ALPHA-D-GLUCOPYRANOSYL)OXY]-2-HYDROXYCYCLOHEXYL 2,6-DIAMINO-2,6-DIDEOXY-ALPHA-D-GLUCOPYRANOSIDE, Aminoglycoside 6-N-acetyltransferase type Ib11, COENZYME A 著者 Maurice, F, Broutin, I, Podglajen, I, Benas, P, Collatz, E, Dardel, F. 登録日 2007-07-05 公開日 2008-04-08 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Enzyme structural plasticity and the emergence of broad-spectrum antibiotic resistance. Embo Rep., 9, 2008
2QIE	Staphylococcus aureus molybdopterin synthase in complex with precursor Z 分子名称: (2R,4AR,5AR,11AR,12AS)-8-AMINO-2-HYDROXY-4A,5A,9,11,11A,12A-HEXAHYDRO[1,3,2]DIOXAPHOSPHININO[4',5':5,6]PYRANO[3,2-G]PTERIDINE-10,12(4H,6H)-DIONE 2-OXIDE, Molybdopterin synthase small subunit, Molybdopterin-converting factor subunit 2 著者 Daniels, J.N, Schindelin, H. 登録日 2007-07-04 公開日 2008-02-19 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of a molybdopterin synthase-precursor Z complex: insight into its sulfur transfer mechanism and its role in molybdenum cofactor deficiency. Biochemistry, 47, 2008
4J88	Dark-state structure of sfGFP containing the unnatural amino acid p-azido-phenylalanine at residue 66 分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Green fluorescent protein, ... 著者 Reddington, S.C, Jones, D.D, Rizkallah, P.J, Tippmann, E.M. 登録日 2013-02-14 公開日 2013-06-26 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.08 Å) 主引用文献 Different Photochemical Events of a Genetically Encoded Phenyl Azide Define and Modulate GFP Fluorescence. Angew.Chem.Int.Ed.Engl., 52, 2013
4J9C	Crystal structure of the Abl-SH3 domain H59Q-N96T mutant complexed with the designed high-affinity peptide ligand P17 分子名称: DI(HYDROXYETHYL)ETHER, P17, TRIETHYLENE GLYCOL, ... 著者 Camara-Artigas, A. 登録日 2013-02-16 公開日 2014-01-29 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.051 Å) 主引用文献 Crystal structure of the Abl-SH3 domain H59Q-N96T mutant complexed with the designed high-affinity peptide ligand P17 To be Published
4I1Y	The structure of Cysteine synthase from Mycobacterium ulcerans Agy99 分子名称: CHLORIDE ION, Cysteine synthase, SULFATE ION 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2012-11-21 公開日 2012-12-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
3EGB	Structure of Pellino2 FHA domain at 3.3 Angstroms resolution. 分子名称: Protein pellino homolog 2 著者 Ferguson, K.M, Lin, C, Schmitz, K.R. 登録日 2008-09-10 公開日 2008-12-23 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3.25 Å) 主引用文献 Pellino proteins contain a cryptic FHA domain that mediates interaction with phosphorylated IRAK1. Structure, 16, 2008
4I3E	Crystal structure of Staphylococcal IMPase - I complexed with products. 分子名称: GLYCEROL, Inositol monophosphatase family protein, MAGNESIUM ION, ... 著者 Bhattacharyya, S, Dutta, A, Dutta, D, Das, A.K. 登録日 2012-11-26 公開日 2013-12-18 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal structure of Staphylococcal IMPase - I complexed with products. To be Published
4I3Y	Crystal structure of Staphylococcal inositol monophosphatase-1: 100 mM LiCl soaked inhibitory complex 分子名称: GLYCEROL, Inositol monophosphatase family protein, MAGNESIUM ION, ... 著者 Dutta, A, Bhattacharyya, S, Dutta, D, Das, A.K. 登録日 2012-11-26 公開日 2013-11-27 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Structural elucidation of the binding site and mode of inhibition of Li(+) and Mg(2+) in inositol monophosphatase. Febs J., 281, 2014
3EHS	Crystal structure of the extracellular domain of human corticotropin releasing factor receptor type 1 (CRFR1) 分子名称: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, fusion protein of CRFR1 extracellular domain and MBP 著者 Pioszak, A.A, Xu, H.E. 登録日 2008-09-14 公開日 2008-09-30 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.76 Å) 主引用文献 Molecular Recognition of Corticotropin-releasing Factor by Its G-protein-coupled Receptor CRFR1. J.Biol.Chem., 283, 2008
3EDH	Crystal structure of bone morphogenetic protein 1 protease domain in complex with partially bound DMSO 分子名称: ACETYL GROUP, Bone morphogenetic protein 1, DIMETHYL SULFOXIDE, ... 著者 Mac Sweeney, A. 登録日 2008-09-03 公開日 2008-09-16 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Structural basis for the substrate specificity of bone morphogenetic protein 1/tolloid-like metalloproteases To be Published
3U2D	S. aureus GyrB ATPase domain in complex with small molecule inhibitor 分子名称: 4-bromo-5-methyl-N-[1-(3-nitropyridin-2-yl)piperidin-4-yl]-1H-pyrrole-2-carboxamide, DNA gyrase subunit B, MAGNESIUM ION 著者 Boriack-Sjodin, P.A, Prince, D.B, Eakin, A.E, Sherer, B.A. 登録日 2011-10-03 公開日 2012-01-11 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Pyrrolamide DNA gyrase inhibitors: fragment-based nuclear magnetic resonance screening to identify antibacterial agents. Antimicrob.Agents Chemother., 56, 2012
3TLX	Crystal Structure of PF10_0086, adenylate kinase from plasmodium falciparum 分子名称: ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... 著者 Wernimont, A.K, Loppnau, P, Crombet, L, Weadge, J, Perieteanu, A, Edwards, A.M, Arrowsmith, C.H, Park, H, Bountra, C, Hui, R, Amani, M, Structural Genomics Consortium (SGC) 登録日 2011-08-30 公開日 2011-10-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Crystal Structure of PF10_0086, adenylate kinase from plasmodium falciparum TO BE PUBLISHED

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