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7AV9
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Crystal Structure of the second bromodomain of Pleckstrin homology domain interacting protein (PHIP) in space group C2
分子名称: 1,2-ETHANEDIOL, PH-interacting protein
著者Krojer, T, Talon, R, Fairhead, M, Szykowska, A, Burgess-Brown, N.A, Brennan, P.E, Arrowsmith, C.H, Edwards, A.M, Bountra, C, von Delft, F.
登録日2020-11-04
公開日2021-01-13
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.23 Å)
主引用文献Crystal Structure of the second bromodomain of Pleckstrin homology domain interacting protein (PHIP) in space group C2
To Be Published
7BBP
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Crystal Structure of the second bromodomain of Pleckstrin homology domain interacting protein (PHIP) in complex with H4K5acK8ac
分子名称: 1,2-ETHANEDIOL, ACETATE ION, Histone H4, ...
著者Krojer, T, Talon, R, Fairhead, M, Szykowska, A, Burgess-Brown, N.A, Brennan, P.E, Arrowsmith, C.H, Edwards, A.M, Bountra, C, von Delft, F, Structural Genomics Consortium (SGC)
登録日2020-12-18
公開日2021-03-03
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Crystal Structure of the second bromodomain of Pleckstrin homology domain interacting protein (PHIP) in complex with H4K5acK8ac
To Be Published
2C4C
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Crystal structure of the NADPH-treated monooxygenase domain of MICAL
分子名称: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, NEDD9-INTERACTING PROTEIN WITH CALPONIN HOMOLOGY AND LIM DOMAINS
著者Siebold, C, Berrow, N, Walter, T.S, Harlos, K, Owens, R.J, Terman, J.R, Stuart, D.I, Kolodkin, A.L, Pasterkamp, R.J, Jones, E.Y.
登録日2005-10-18
公開日2005-10-26
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献High-Resolution Structure of the Catalytic Region of Mical (Molecule Interacting with Casl), a Multidomain Flavoenzyme-Signaling Molecule.
Proc.Natl.Acad.Sci.USA, 102, 2005
6JLR
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Crystal structure of wild type MNK2 in complex with inhibitor
分子名称: 4-[5-(1-methylpyrazol-4-yl)pyridin-3-yl]benzamide, MAP kinase-interacting serine/threonine-protein kinase 2
著者Baburajendran, N, Hill, J.
登録日2019-03-06
公開日2020-02-12
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.901 Å)
主引用文献Stepwise Evolution of Fragment Hits against MAPK Interacting Kinases 1 and 2.
J.Med.Chem., 63, 2020
2GZD
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Crystal Structure of Rab11 in Complex with Rab11-FIP2
分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Rab11 family-interacting protein 2, ...
著者Khan, A.R.
登録日2006-05-11
公開日2006-08-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献Crystal structure of rab11 in complex with rab11 family interacting protein 2.
Structure, 14, 2006
2HW7
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Crystal Structure of Mnk2-D228G in complex with Staurosporine
分子名称: MAP kinase-interacting serine/threonine-protein kinase 2, STAUROSPORINE, ZINC ION
著者Jauch, R, Wahl, M.C.
登録日2006-08-01
公開日2006-08-29
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Mitogen-activated protein kinases interacting kinases are autoinhibited by a reprogrammed activation segment.
Embo J., 25, 2006
2HW6
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Crystal structure of Mnk1 catalytic domain
分子名称: MAP kinase-interacting serine/threonine-protein kinase 1, SULFATE ION
著者Jauch, R, Wahl, M.C.
登録日2006-08-01
公開日2006-08-29
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Mitogen-activated protein kinases interacting kinases are autoinhibited by a reprogrammed activation segment.
Embo J., 25, 2006
1E2L
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Kinetics and crystal structure of the wild-type and the engineered Y101F mutant of Herpes simplex virus type 1 thymidine kinase interacting with (North)-methanocarba-thymidine
分子名称: 1-[4-HYDROXY-5-(HYDROXYMETHYL)BICYCLO[3.1.0]HEX-2-YL]-5-METHYLPYRIMIDINE-2,4(1H,3H)-DIONE, SULFATE ION, THYMIDINE KINASE
著者Vogt, J, Scapozza, L, Schulz, G.E.
登録日2000-05-23
公開日2000-08-18
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Kinetics and Crystal Structure of the Wild-Type and the Engineered Y101F Mutant of Herpes Simplex Virus Type 1 Thymidine Kinase Interacting with (North)-Methanocarba-Thymidine
Biochemistry, 39, 2000
1E2K
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Kinetics and crystal structure of the wild-type and the engineered Y101F mutant of Herpes simplex virus type 1 thymidine kinase interacting with (North)-methanocarba-thymidine
分子名称: 1-[4-HYDROXY-5-(HYDROXYMETHYL)BICYCLO[3.1.0]HEX-2-YL]-5-METHYLPYRIMIDINE-2,4(1H,3H)-DIONE, SULFATE ION, THYMIDINE KINASE
著者Vogt, J, Scapozza, L, Schulz, G.E.
登録日2000-05-23
公開日2000-08-19
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Kinetics and Crystal Structure of the Wild-Type and the Engineered Y101F Mutant of Herpes Simplex Virus Type 1 Thymidine Kinase Interacting with (North)-Methanocarba-Thymidine
Biochemistry, 39, 2000
3BXW
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Crystal Structure of Stabilin-1 Interacting Chitinase-Like Protein, SI-CLP
分子名称: Chitinase domain-containing protein 1, SULFATE ION
著者Meng, G, Green, T.J.
登録日2008-01-15
公開日2009-01-20
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of human stabilin-1 interacting chitinase-like protein (SI-CLP) reveals a saccharide-binding cleft with lower sugar-binding selectivity.
J.Biol.Chem., 285, 2010
7NRI
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Structure of the darobactin-bound E. coli BAM complex (BamABCDE)
分子名称: 3-PYRIDIN-4-YL-2,4-DIHYDRO-INDENO[1,2-.C.]PYRAZOLE, Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, ...
著者Jakob, R.P, Kaur, H, Marzinek, J.K, Green, R, Imai, Y, Bolla, J, Robinson, C, Bond, P.J, Lewis, K, Maier, T, Hiller, S.
登録日2021-03-03
公開日2021-04-21
最終更新日2021-05-19
実験手法ELECTRON MICROSCOPY (3.03 Å)
主引用文献The antibiotic darobactin mimics a beta-strand to inhibit outer membrane insertase.
Nature, 593, 2021
8PR2
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Cytoplasmic dynein-1 heavy chain bound to JIP3-LZI
分子名称: C-Jun-amino-terminal kinase-interacting protein 3, Cytoplasmic dynein 1 heavy chain 1, Cytoplasmic dynein 1 intermediate chain 2, ...
著者Singh, K, Lau, C.K, Manigrasso, G, Gassmann, R, Carter, A.P.
登録日2023-07-12
公開日2024-03-27
最終更新日2024-04-10
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Molecular mechanism of dynein-dynactin complex assembly by LIS1.
Science, 383, 2024
8PR3
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Cytoplasmic dynein-1 heavy chain bound to JIP3-RH1
分子名称: C-Jun-amino-terminal kinase-interacting protein 3, Cytoplasmic dynein 1 heavy chain 1, Cytoplasmic dynein 1 intermediate chain 2, ...
著者Singh, K, Lau, C.K, Manigrasso, G, Gassmann, R, Carter, A.P.
登録日2023-07-12
公開日2024-03-27
最終更新日2024-04-10
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Molecular mechanism of dynein-dynactin complex assembly by LIS1.
Science, 383, 2024
2JTT
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Solution structure of calcium loaded S100A6 bound to C-terminal Siah-1 interacting protein
分子名称: Calcyclin-binding protein, Protein S100-A6
著者Lee, Y, Chazin, W.J.
登録日2007-08-06
公開日2008-08-19
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structure of the S100A6 complex with a fragment from the C-terminal domain of Siah-1 interacting protein: a novel mode for S100 protein target recognition.
Biochemistry, 47, 2008
7LRN
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Structure of the Siderophore Interacting Protein from Acinetbacter baumannii
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, NADPH-dependent ferric siderophore reductase
著者Tanner, J.J, Korasick, D.A.
登録日2021-02-16
公開日2021-07-21
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structural and Biochemical Characterization of the Flavin-Dependent Siderophore-Interacting Protein from Acinetobacter baumannii .
Acs Omega, 6, 2021
4FXB
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Crystal structure of CYP105N1 from Streptomyces coelicolor: a cytochrome P450 oxidase in the coelibactin siderophore biosynthetic pathway
分子名称: PROTOPORPHYRIN IX CONTAINING FE, Putative cytochrome P450
著者Hong, M.K, Lim, Y.R, Kim, J.K, Kim, D.H, Kang, L.W.
登録日2012-07-03
公開日2012-11-14
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of cytochrome P450 CYP105N1 from Streptomyces coelicolor, an oxidase in the coelibactin siderophore biosynthetic pathway
Arch.Biochem.Biophys., 528, 2012
2L7C
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Biophysical studies of lipid interacting regions of DGD2 in Arabidopsis thaliana
分子名称: Digalactosyldiacylglycerol synthase 2, chloroplastic
著者Szpryngiel, S, Ge, C, Iakovleva, I, Lind, J, Wieslander, A, Maler, L.
登録日2010-12-07
公開日2011-10-19
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Lipid interacting regions in phosphate stress glycosyltransferase atDGD2 from Arabidopsis thaliana.
Biochemistry, 50, 2011
6UL8
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RIP2 kinase catalytic domain complex with (5S,6S,8R)-2-(benzo[d]thiazol-5-yl)-6-hydroxy-4,5,6,7,8,9-hexahydro-5,8-methanopyrazolo[1,5-a][1,3]diazocine-3-carboxamide
分子名称: (5S,6S,8R)-2-(1,3-benzothiazol-5-yl)-6-hydroxy-4,5,6,7,8,9-hexahydro-5,8-methanopyrazolo[1,5-a][1,3]diazocine-3-carboxamide, CALCIUM ION, Receptor-interacting serine/threonine-protein kinase 2
著者Shewchuk, L.M, Convery, M.A.
登録日2019-10-07
公開日2019-12-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献Discovery of Pyrazolocarboxamides as Potent and Selective Receptor Interacting Protein 2 (RIP2) Kinase Inhibitors.
Acs Med.Chem.Lett., 10, 2019
4LA7
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X-ray crystal structure of the PYL2-quinabactin-Hab1 ternary complex
分子名称: ACETATE ION, Abscisic acid receptor PYL2, GLYCEROL, ...
著者Peterson, F.C, Volkman, B.F, Cutler, S.R.
登録日2013-06-19
公開日2013-08-07
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Activation of dimeric ABA receptors elicits guard cell closure, ABA-regulated gene expression, and drought tolerance.
Proc.Natl.Acad.Sci.USA, 110, 2013
7RMA
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Structure of the fourth UIM (Ubiquitin Interacting Motif) of ANKRD13D in complex with a high affinity UbV (Ubiquitin Variant)
分子名称: Ankyrin repeat domain-containing protein 13D, SODIUM ION, SULFATE ION, ...
著者Singer, A.U, Manczyk, N, Veggiani, G, Sicheri, F, Sidhu, S.S.
登録日2021-07-27
公開日2022-05-11
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Panel of Engineered Ubiquitin Variants Targeting the Family of Human Ubiquitin Interacting Motifs.
Acs Chem.Biol., 17, 2022
6MFL
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Structure of siderophore binding protein BauB bound to a complex between two molecules of acinetobactin and ferric iron.
分子名称: 1,2-ETHANEDIOL, FE (III) ION, Siderophore Binding Protein BauB, ...
著者Gulick, A.M, Bailey, D.C, Wencewicz, T.A.
登録日2018-09-11
公開日2018-11-21
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structure of the Siderophore Binding Protein BauB Bound to an Unusual 2:1 Complex Between Acinetobactin and Ferric Iron.
Biochemistry, 57, 2018
4ZHD
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Siderocalin-mediated recognition and cellular uptake of actinides
分子名称: GLYCEROL, Neutrophil gelatinase-associated lipocalin, PLUTONIUM ION, ...
著者Allred, B.E, Rupert, P.B, Gauny, S.S, An, D.D, Ralston, C.Y, Sturzbecher-Hoehne, M, Strong, R.K, Abergel, R.J.
登録日2015-04-24
公開日2015-08-05
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Siderocalin-mediated recognition, sensitization, and cellular uptake of actinides.
Proc.Natl.Acad.Sci.USA, 112, 2015
4ZHH
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Siderocalin-mediated recognition and cellular uptake of actinides
分子名称: CHLORIDE ION, GLYCEROL, N,N'-butane-1,4-diylbis[1-hydroxy-N-(3-{[(1-hydroxy-6-oxo-1,6-dihydropyridin-2-yl)carbonyl]amino}propyl)-6-oxo-1,6-dihydropyridine-2-carboxamide], ...
著者Allred, B.E, Rupert, P.B, Gauny, S.S, An, D.D, Ralston, C.Y, Sturzbecher-Hoehne, M, Strong, R.K, Abergel, R.J.
登録日2015-04-24
公開日2015-08-05
最終更新日2015-09-02
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Siderocalin-mediated recognition, sensitization, and cellular uptake of actinides.
Proc.Natl.Acad.Sci.USA, 112, 2015
4ZHG
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Siderocalin-mediated recognition and cellular uptake of actinides
分子名称: AMERICIUM ION, CHLORIDE ION, GLYCEROL, ...
著者Allred, B.E, Rupert, P.B, Gauny, S.S, An, D.D, Ralston, C.Y, Sturzbecher-Hoehne, M, Strong, R.K, Abergel, R.J.
登録日2015-04-24
公開日2015-08-05
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Siderocalin-mediated recognition, sensitization, and cellular uptake of actinides.
Proc.Natl.Acad.Sci.USA, 112, 2015
4ZHC
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Siderocalin-mediated recognition and cellular uptake of actinides
分子名称: ACETATE ION, N-{2-[bis(2-{[(2,3-dihydroxyphenyl)carbonyl]amino}ethyl)amino]ethyl}-1-hydroxy-6-oxo-1,6-dihydropyridine-2-carboxamide, Neutrophil gelatinase-associated lipocalin, ...
著者Allred, B.E, Rupert, P.B, Gauny, S.S, An, D.D, Ralston, C.Y, Sturzbecher-Hoehne, M, Strong, R.K, Abergel, R.J.
登録日2015-04-24
公開日2015-08-05
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Siderocalin-mediated recognition, sensitization, and cellular uptake of actinides.
Proc.Natl.Acad.Sci.USA, 112, 2015

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