PDB: 2705 件ウェブページステータス検索Chemie searchBIRD

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2J7L	E. coli P Pilus chaperone PapD in complex with a pilus biogenesis inhibitor, pilicide 2c 分子名称: (3R)-8-CYCLOPROPYL-6-(MORPHOLIN-4-YLMETHYL)-7-(1-NAPHTHYLMETHYL)-5-OXO-2,3-DIHYDRO-5H-[1,3]THIAZOLO[3,2-A]PYRIDINE-3-CARBOXYLIC ACID, CHAPERONE PROTEIN PAPD 著者 Remaut, H, Pinkner, J.S, Hultgren, S.J, Almqvist, F, Waksman, G. 登録日 2006-10-12 公開日 2006-11-01 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Rationally Designed Small Compounds Inhibit Pilus Biogenesis in Uropathogenic Bacteria. Proc.Natl.Acad.Sci.USA, 103, 2006
1KIU	FimH adhesin Q133N mutant-FimC chaperone complex with methyl-alpha-D-mannose 分子名称: CHAPERONE PROTEIN FimC, FimH PROTEIN, methyl alpha-D-mannopyranoside 著者 Hung, C.S, Bouckaert, J. 登録日 2001-12-03 公開日 2002-06-05 最終更新日 2021-10-27 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural basis of tropism of Escherichia coli to the bladder during urinary tract infection. Mol.Microbiol., 44, 2002
3RFZ	Crystal structure of the FimD usher bound to its cognate FimC:FimH substrate 分子名称: Chaperone protein fimC, Outer membrane usher protein, type 1 fimbrial synthesis, ... 著者 Phan, G, Remaut, H, Lebedev, A, Geibel, S, Waksman, G. 登録日 2011-04-07 公開日 2011-06-01 最終更新日 2012-03-28 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structure of the FimD usher bound to its cognate FimC-FimH substrate. Nature, 474, 2011
2J2Z	X-Ray Structure of the Chaperone PapD in complex with the Pilus terminator subunit PapH at 2.3 Angstrom resolution 分子名称: CHAPERONE PROTEIN PAPD, COBALT (II) ION, PAP FIMBRIAL MINOR PILIN PROTEIN, ... 著者 Verger, D, Miller, E, Remaut, H, Waksman, G, Hultgren, S. 登録日 2006-08-17 公開日 2006-11-08 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Molecular Mechanism of P Pilus Termination in Uropathogenic Escherichia Coli. Embo Rep., 7, 2006
6E0E	Crystal structure of Glucokinase in complex with compound 6 分子名称: 2-({2-[(4-methyl-1,3-thiazol-2-yl)amino]pyridin-3-yl}oxy)benzonitrile, Glucokinase, alpha-D-glucopyranose 著者 Hinklin, R.J, Baer, B.R, Boyd, S.A, Chicarelli, M.D, Condroski, K.R, DeWolf, W.E, Fischer, J, Frank, M, Hingorani, G.P, Lee, P.A, Neitzel, N.A, Pratt, S.A, Singh, A, Sullivan, F.X, Turner, T, Voegtli, W.C, Wallace, E.M, Williams, L, Aicher, T.D. 登録日 2018-07-06 公開日 2019-07-10 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Discovery and preclinical development of AR453588 as an anti-diabetic glucokinase activator. Bioorg.Med.Chem., 28, 2020
6E14	Handover mechanism of the growing pilus by the bacterial outer membrane usher FimD 分子名称: Chaperone protein FimC, Fimbrial biogenesis outer membrane usher protein, Protein FimF, ... 著者 Du, M, Yuan, Z, Yu, H, Henderson, N, Sarowar, S, Zhao, G, Werneburg, G.T, Thanassi, D.G, Li, H. 登録日 2018-07-09 公開日 2018-10-17 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Handover mechanism of the growing pilus by the bacterial outer-membrane usher FimD. Nature, 562, 2018
3QIC	The structure of human glucokinase E339K mutation 分子名称: GLYCEROL, Glucokinase, alpha-D-glucopyranose 著者 Liu, Q, Liu, S, Liu, J. 登録日 2011-01-27 公開日 2011-06-01 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of E339K mutated human glucokinase reveals changes in the ATP binding site. Febs Lett., 585, 2011
1KLF	FIMH ADHESIN-FIMC CHAPERONE COMPLEX WITH D-MANNOSE 分子名称: CHAPERONE PROTEIN FIMC, FIMH PROTEIN, alpha-D-mannopyranose 著者 Hung, C.S, Bouckaert, J. 登録日 2001-12-11 公開日 2002-06-05 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.79 Å) 主引用文献 Structural basis of tropism of Escherichia coli to the bladder during urinary tract infection. Mol.Microbiol., 44, 2002
1HKG	STRUCTURAL DYNAMICS OF YEAST HEXOKINASE DURING CATALYSIS 分子名称: HEXOKINASE A 著者 Bennett Jr, W.S, Steitz, T.A. 登録日 1980-12-22 公開日 1981-02-26 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Structural dynamics of yeast hexokinase during catalysis. Philos.Trans.R.Soc.London,Ser.B, 293, 1981
1HKC	RECOMBINANT HUMAN HEXOKINASE TYPE I COMPLEXED WITH GLUCOSE AND PHOSPHATE 分子名称: D-GLUCOSE 6-PHOSPHOTRANSFERASE, PHOSPHATE ION, POTASSIUM ION, ... 著者 Aleshin, A.E, Honzatko, R.B. 登録日 1998-07-01 公開日 1998-11-11 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Regulation of hexokinase I: crystal structure of recombinant human brain hexokinase complexed with glucose and phosphate. J.Mol.Biol., 282, 1998
2AKI	Normal mode-based flexible fitted coordinates of a translocating SecYEG protein-conducting channel into the cryo-EM map of a SecYEG-nascent chain-70S ribosome complex from E. coli 分子名称: Preprotein translocase secE subunit, Preprotein translocase secY subunit, Protein-export membrane protein secG 著者 Mitra, K, Schaffitzel, C, Shaikh, T, Tama, F, Jenni, S, Brooks III, C.L, Ban, N, Frank, J. 登録日 2005-08-03 公開日 2005-11-15 最終更新日 2024-02-14 実験手法 ELECTRON MICROSCOPY (14.9 Å) 主引用文献 Structure of the E. coli protein-conducting channel bound to a translating ribosome. Nature, 438, 2005
1L4I	Crystal Structure of the Periplasmic Chaperone SfaE 分子名称: SfaE PROTEIN 著者 Knight, S.D, Choudhury, D, Hultgren, S, Pinkner, J, Stojanoff, V, Thompson, A. 登録日 2002-03-05 公開日 2002-06-12 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure of the S pilus periplasmic chaperone SfaE at 2.2 A resolution. Acta Crystallogr.,Sect.D, 58, 2002
3O1B	CRYSTAL STRUCTURE OF DIMERIC KLHXK1 IN CRYSTAL FORM II 分子名称: Hexokinase 著者 Kuettner, E.B, Kettner, K, Keim, A, Kriegel, T.M, Strater, N. 登録日 2010-07-21 公開日 2010-10-13 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal Structure of Hexokinase KlHxk1 of Kluyveromyces lactis: A MOLECULAR BASIS FOR UNDERSTANDING THE CONTROL OF YEAST HEXOKINASE FUNCTIONS VIA COVALENT MODIFICATION AND OLIGOMERIZATION. J.Biol.Chem., 285, 2010
3BWU	Crystal structure of the ternary complex of FimD (N-Terminal Domain, FimDN) with FimC and the N-terminally truncated pilus subunit FimF (FimFt) 分子名称: 1,2-ETHANEDIOL, Chaperone protein fimC, DI(HYDROXYETHYL)ETHER, ... 著者 Eidam, O, Grutter, M.G, Capitani, G. 登録日 2008-01-10 公開日 2008-03-04 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 Crystal structure of the ternary FimC-FimF(t)-FimD(N) complex indicates conserved pilus chaperone-subunit complex recognition by the usher FimD Febs Lett., 582, 2008
2YHX	SEQUENCING A PROTEIN BY X-RAY CRYSTALLOGRAPHY. II. REFINEMENT OF YEAST HEXOKINASE B CO-ORDINATES AND SEQUENCE AT 2.1 ANGSTROMS RESOLUTION 分子名称: 2-deoxy-2-{[(2-methylphenyl)carbonyl]amino}-alpha-D-glucopyranose, HEXOKINASE B 著者 Steitz, T.A, Anderson, C.M, Stenkamp, R.E. 登録日 1978-03-20 公開日 1978-05-23 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Sequencing a protein by x-ray crystallography. II. Refinement of yeast hexokinase B co-ordinates and sequence at 2.1 A resolution. J.Mol.Biol., 123, 1978
2YXR	The plug domain of the SecY protein stablizes the closed state of the translocation channel and maintains a membrane seal 分子名称: Preprotein translocase secG subunit, Preprotein translocase subunit secE, Preprotein translocase subunit secY 著者 Li, W, Schulman, S. 登録日 2007-04-27 公開日 2007-08-14 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 The plug domain of the SecY protein stabilizes the closed state of the translocation channel and maintains a membrane seal Mol.Cell, 26, 2007
6SWH	Crystal structure of the ternary complex between the type 1 pilus proteins FimC, FimI and FimA from E. coli 分子名称: 1,2-ETHANEDIOL, Chaperone protein FimC, DI(HYDROXYETHYL)ETHER, ... 著者 Giese, C, Puorger, C, Ignatov, O, Weber, M, Scharer, M.A, Capitani, G, Glockshuber, R. 登録日 2019-09-20 公開日 2020-10-07 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Comprehensive kinetic characterization of bacterial pilus rod assembly and assembly termination To Be Published
6FQA	Crystal structure of the CsuC-CsuA/B chaperone-subunit preassembly complex of the archaic chaperone-usher Csu pili of Acinetobacter baumannii 分子名称: CsuA/B,CsuA/B, CsuC 著者 Parilova, O, Pakharukova, N.A, Malmi, H, Tuitilla, M, Paavilainen, S, Zavialov, A.V. 登録日 2018-02-13 公開日 2018-09-26 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Archaic and alternative chaperones preserve pilin folding energy by providing incomplete structural information. J. Biol. Chem., 293, 2018
4V4N	Structure of the Methanococcus jannaschii ribosome-SecYEBeta channel complex 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein L7AE, ... 著者 Menetret, J.F, Park, E, Gumbart, J.C, Ludtke, S.J, Li, W, Whynot, A, Rapoport, T.A, Akey, C.W. 登録日 2013-06-17 公開日 2014-07-09 最終更新日 2024-02-28 実験手法 ELECTRON MICROSCOPY (9 Å) 主引用文献 Structure of the SecY channel during initiation of protein translocation. Nature, 506, 2013
2YXQ	The plug domain of the SecY protein stablizes the closed state of the translocation channel and maintains a membrane seal 分子名称: Preprotein translocase secG subunit, Preprotein translocase subunit secE, Preprotein translocase subunit secY 著者 Li, W, Schulman, S. 登録日 2007-04-27 公開日 2007-08-14 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 The plug domain of the SecY protein stabilizes the closed state of the translocation channel and maintains a membrane seal Mol.Cell, 26, 2007
2XAC	Structural Insights into the Binding of VEGF-B by VEGFR-1D2: Recognition and Specificity 分子名称: GLYCEROL, VASCULAR ENDOTHELIAL GROWTH FACTOR B, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 1 著者 Iyer, S, Darley, P, Acharya, K.R. 登録日 2010-03-30 公開日 2010-05-19 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.71 Å) 主引用文献 Structural Insights Into the Binding of Vegf-B by Vegfr-1D2: Recognition and Specificity J.Biol.Chem., 285, 2010
7LHG	Cryo-EM structure of E. coli P pilus tip assembly intermediate PapC-PapD-PapK-PapG in the first conformation 分子名称: Chaperone protein PapD, Fimbrial adapter PapK, P fimbria tip G-adhesin PapG-II, ... 著者 Du, M, Yuan, Z, Werneburg, G, Henderson, N, Chauhan, H, Kovach, A, Zhao, G, Johl, J, Li, H, Thanassi, D. 登録日 2021-01-23 公開日 2021-08-11 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Processive dynamics of the usher assembly platform during uropathogenic Escherichia coli P pilus biogenesis. Nat Commun, 12, 2021
7LHH	Cryo-EM structure of E. coli P pilus tip assembly intermediate PapC-PapD-PapK-PapG in the second conformation 分子名称: Chaperone protein PapD, Fimbrial adapter PapK, P fimbria tip G-adhesin PapG-II, ... 著者 Du, M, Yuan, Z, Werneburg, G, Henderson, N, Chauhan, H, Kovach, A, Zhao, G, Johl, J, Li, H, Thanassi, D. 登録日 2021-01-23 公開日 2021-08-11 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (7.2 Å) 主引用文献 Processive dynamics of the usher assembly platform during uropathogenic Escherichia coli P pilus biogenesis. Nat Commun, 12, 2021
7LHI	Cryo-EM structure of E. coli P pilus tip assembly intermediate PapC-PapD-PapK-PapF-PapG 分子名称: Chaperone protein PapD, Fimbrial adapter PapK, Fimbrial protein, ... 著者 Du, M, Yuan, Z, Werneburg, G, Henderson, N, Chauhan, H, Kovach, A, Zhao, G, Johl, J, Li, H, Thanassi, D. 登録日 2021-01-23 公開日 2021-08-11 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (7.6 Å) 主引用文献 Processive dynamics of the usher assembly platform during uropathogenic Escherichia coli P pilus biogenesis. Nat Commun, 12, 2021
5O4E	Crystal structure of VEGF in complex with heterodimeric Fcab JanusCT6 分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... 著者 Mlynek, G, Lobner, E, Kubinger, K, Humm, A, Obinger, C, Djinovic-Carugo, K. 登録日 2017-05-29 公開日 2017-08-30 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Two-faced Fcab prevents polymerization with VEGF and reveals thermodynamics and the 2.15 angstrom crystal structure of the complex. MAbs, 9, 2017

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