PDB: 71589 件ウェブページステータス検索Chemie searchBIRD

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5VNE	Crystal structure of Sec23a/Sec24a/Sec22 complexed with Emp24 sorting motif 分子名称: EMP24, Protein transport protein Sec23A, Protein transport protein Sec24A, ... 著者 Ma, W, Goldberg, J. 登録日 2017-04-30 公開日 2017-07-05 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.698 Å) 主引用文献 ER retention is imposed by COPII protein sorting and attenuated by 4-phenylbutyrate. Elife, 6, 2017
4P0J	Crystal Structure of Loop-Swapped Interleukin-36Ra 分子名称: Interleukin-36 receptor antagonist/Interleukin-36 gamma chimera protein 著者 Guenther, S, Sundberg, E.J. 登録日 2014-02-21 公開日 2014-06-25 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.298 Å) 主引用文献 Molecular Determinants of Agonist and Antagonist Signaling through the IL-36 Receptor. J Immunol., 193, 2014
5VNI	Crystal structure of Sec23a/Sec24a/Sec22 complexed with a C-terminal FA sorting motif 分子名称: C-terminal FA, Protein transport protein Sec23A, Protein transport protein Sec24A, ... 著者 Ma, W, Goldberg, J. 登録日 2017-04-30 公開日 2017-07-05 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.788 Å) 主引用文献 ER retention is imposed by COPII protein sorting and attenuated by 4-phenylbutyrate. Elife, 6, 2017
5Q0T	Ligand binding to FARNESOID-X-RECEPTOR 分子名称: 2-phenyl-N-(propan-2-yl)-6-[(thiophen-2-yl)sulfonyl]-4,5,6,7-tetrahydro-1H-pyrrolo[2,3-c]pyridine-1-carboxamide, Bile acid receptor, COACTIVATOR PEPTIDE SRC-1 HD3 著者 Rudolph, M.G, Benz, J, Burger, D, Thoma, R, Ruf, A, Joseph, C, Kuhn, B, Shao, C, Yang, H, Burley, S.K. 登録日 2017-05-31 公開日 2017-07-05 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 D3R Grand Challenge 2: blind prediction of protein-ligand poses, affinity rankings, and relative binding free energies. J. Comput. Aided Mol. Des., 32, 2018
5Q11	Ligand binding to FARNESOID-X-RECEPTOR 分子名称: Bile acid receptor, COACTIVATOR PEPTIDE SRC-1 HD3, N,N-dicyclohexyl-3-(2,4-dichlorophenyl)-5-methyl-1,2-oxazole-4-carboxamide 著者 Rudolph, M.G, Benz, J, Burger, D, Thoma, R, Ruf, A, Joseph, C, Kuhn, B, Shao, C, Yang, H, Burley, S.K. 登録日 2017-05-31 公開日 2017-07-05 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 D3R Grand Challenge 2: blind prediction of protein-ligand poses, affinity rankings, and relative binding free energies. J. Comput. Aided Mol. Des., 32, 2018
5Q18	Ligand binding to FARNESOID-X-RECEPTOR 分子名称: (2S)-2-cyclohexyl-2-{5,6-difluoro-2-[(R)-methoxy(phenyl)methyl]-1H-benzimidazol-1-yl}-N-(trans-4-hydroxycyclohexyl)acetamide, Bile acid receptor, COACTIVATOR PEPTIDE SRC-1 HD3 著者 Rudolph, M.G, Benz, J, Burger, D, Thoma, R, Ruf, A, Joseph, C, Kuhn, B, Shao, C, Yang, H, Burley, S.K. 登録日 2017-05-31 公開日 2017-07-05 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 D3R Grand Challenge 2: blind prediction of protein-ligand poses, affinity rankings, and relative binding free energies. J. Comput. Aided Mol. Des., 32, 2018
4OIF	3D structure of Gan42B, a GH42 beta-galactosidase from G. 分子名称: Beta-galactosidase, GLYCEROL, ZINC ION 著者 Solomon, H.V, Tabachnikov, O, Feinberg, H, Shoham, Y, Shoham, G. 登録日 2014-01-19 公開日 2015-02-04 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.448 Å) 主引用文献 Crystallization and preliminary crystallographic analysis of GanB, a GH42 intracellular beta-galactosidase from Geobacillus stearothermophilus. Acta Crystallogr.,Sect.F, 69, 2013
4O9H	Structure of Interleukin-6 in complex with a Camelid Fab fragment 分子名称: Heavy Chain of the Camelid Fab fragment 61H7, Interleukin-6, Light Chain of the Camelid Fab fragment 61H7 著者 Klarenbeek, A, Blanchetot, C, Schragel, G, Sadi, A.S, Ongenae, N, Hemrika, W, Wijdenes, J, Spinelli, S, Desmyter, A, Cambillau, C, Hultberg, A, Kretz-rommel, A, Dreier, T, De haard, H.J.W, Roovers, R.C. 登録日 2014-01-02 公開日 2015-04-15 最終更新日 2015-04-29 実験手法 X-RAY DIFFRACTION (2.42 Å) 主引用文献 Combining residues of naturally-occurring Camelid somatic affinity variants yields ultra-potent human therapeutic IL-6 antibodies To be Published
4OGC	Crystal structure of the Type II-C Cas9 enzyme from Actinomyces naeslundii 分子名称: ACETATE ION, HNH endonuclease domain protein, MAGNESIUM ION, ... 著者 Jiang, F, Ma, E, Lin, S, Doudna, J.A. 登録日 2014-01-15 公開日 2014-02-12 最終更新日 2014-03-26 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structures of Cas9 endonucleases reveal RNA-mediated conformational activation. Science, 343, 2014
4P0L	Crystal Structure of Double Loop-Swapped Interleukin-36Ra With Additional Point Mutations 分子名称: Interleukin-36 receptor antagonist/Interleukin-36 gamma chimera protein 著者 Guenther, S, Sundberg, E.J. 登録日 2014-02-21 公開日 2014-06-25 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Molecular Determinants of Agonist and Antagonist Signaling through the IL-36 Receptor. J Immunol., 193, 2014
4O8Q	Crystal structure of bovine MHD domain of the COPI delta subunit at 2.15 A resolution 分子名称: Coatomer subunit delta, FORMIC ACID 著者 Lahav, A, Rozenberg, H, Cassel, D, Adir, N. 登録日 2013-12-29 公開日 2015-01-07 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Structure of the bovine COPI delta subunit mu homology domain at 2.15 angstrom resolution. Acta Crystallogr.,Sect.D, 71, 2015
7JTI	Interphotoreceptor retinoid-binding protein (IRBP) in complex with a monoclonal antibody (F3F5 mAb5) 分子名称: Retinol-binding protein 3, mAb5 Fab heavy chain, mAb5 Fab light chain 著者 Sears, A.E, Albiez, S, Gulati, S, Wang, B, Kiser, P, Kovacik, L, Engel, A, Stahlberg, H, Palczewski, K. 登録日 2020-08-17 公開日 2020-10-07 最終更新日 2020-12-16 実験手法 ELECTRON MICROSCOPY (7.4 Å) 主引用文献 Single particle cryo-EM of the complex between interphotoreceptor retinoid-binding protein and a monoclonal antibody. Faseb J., 34, 2020
7JU4	Radial spoke 2 stalk, IDAc, and N-DRC attached with doublet microtubule 分子名称: 28 kDa inner dynein arm light chain, axonemal, ADENOSINE-5'-TRIPHOSPHATE, ... 著者 Gui, M, Ma, M, Sze-Tu, E, Wang, X, Koh, F, Zhong, E, Berger, B, Davis, J, Dutcher, S, Zhang, R, Brown, A. 登録日 2020-08-19 公開日 2020-12-16 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structures of radial spokes and associated complexes important for ciliary motility. Nat.Struct.Mol.Biol., 28, 2021
4N1L	Crystal structures of NLRP14 pyrin domain reveal a conformational switch mechanism, regulating its molecular interactions 分子名称: NACHT, LRR and PYD domains-containing protein 14 著者 Eibl, C, Hessenberger, M, Wenger, J, Brandstetter, H. 登録日 2013-10-04 公開日 2014-07-16 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.986 Å) 主引用文献 Structures of the NLRP14 pyrin domain reveal a conformational switch mechanism regulating its molecular interactions. Acta Crystallogr.,Sect.D, 70, 2014
4N3A	Crystal Structure of human O-GlcNAc transferase bound to a peptide from HCF-1 pro-repeat 2 (1-26)E10A 分子名称: Host cell factor 1, UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, URIDINE-5'-DIPHOSPHATE 著者 Lazarus, M.B, Herr, W, Walker, S. 登録日 2013-10-06 公開日 2014-01-01 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 HCF-1 is cleaved in the active site of O-GlcNAc transferase. Science, 342, 2013
7JTK	Radial spoke 1 isolated from Chlamydomonas reinhardtii 分子名称: Cytochrome b5 heme-binding domain-containing protein, Dynein 8 kDa light chain, flagellar outer arm, ... 著者 Gui, M, Ma, M, Sze-Tu, E, Wang, X, Koh, F, Zhong, E, Berger, B, Davis, J, Dutcher, S, Zhang, R, Brown, A. 登録日 2020-08-17 公開日 2020-12-16 最終更新日 2021-01-27 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structures of radial spokes and associated complexes important for ciliary motility. Nat.Struct.Mol.Biol., 28, 2021
4N3C	Crystal Structure of human O-GlcNAc Transferase bound to a peptide from HCF-1 pro-repeat2(1-26) and UDP-GlcNAc 分子名称: Host cell factor 1, UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE 著者 Lazarus, M.B, Herr, W, Walker, S. 登録日 2013-10-06 公開日 2014-01-01 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 HCF-1 is cleaved in the active site of O-GlcNAc transferase. Science, 342, 2013
4N42	Crystal structure of allergen protein scam1 from Scadoxus multiflorus 分子名称: PHOSPHATE ION, Xylanase and alpha-amylase inhibitor protein isoform III 著者 Singh, A, Kumar, S, Sinha, M, Kaur, P, Sharma, S, Singh, T.P. 登録日 2013-10-08 公開日 2013-10-30 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of allergen protein scam1 from Scadoxus multiflorus To be published
5Q1E	Ligand binding to FARNESOID-X-RECEPTOR 分子名称: 5-bromo-1-{[4-(1H-tetrazol-5-yl)phenyl]methyl}-1'-(thiophene-2-sulfonyl)spiro[indole-3,4'-piperidin]-2(1H)-one, Bile acid receptor, COACTIVATOR PEPTIDE SRC-1 HD3 著者 Rudolph, M.G, Benz, J, Burger, D, Thoma, R, Ruf, A, Joseph, C, Kuhn, B, Shao, C, Yang, H, Burley, S.K. 登録日 2017-05-31 公開日 2017-07-05 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 D3R Grand Challenge 2: blind prediction of protein-ligand poses, affinity rankings, and relative binding free energies. J. Comput. Aided Mol. Des., 32, 2018
4N1K	Crystal structures of NLRP14 pyrin domain reveal a conformational switch mechanism, regulating its molecular interactions 分子名称: NACHT, LRR and PYD domains-containing protein 14 著者 Eibl, C, Hessenberger, M, Wenger, J, Brandstetter, H. 登録日 2013-10-04 公開日 2014-07-16 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structures of the NLRP14 pyrin domain reveal a conformational switch mechanism regulating its molecular interactions. Acta Crystallogr.,Sect.D, 70, 2014
4OJP	Crystal Structure of Putative Tailspike Protein (TSP1, orf210) from Escherichia coli O157:H7 Bacteriohage CBA120 in Complex with Maltose 分子名称: Tailspike protein, ZINC ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose 著者 Chen, C, Herzberg, O. 登録日 2014-01-21 公開日 2014-03-26 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.948 Å) 主引用文献 Crystal structure of ORF210 from E. coli O157:H1 phage CBA120 (TSP1), a putative tailspike protein. Plos One, 9, 2014
5VNO	Crystal structure of Sec23a/Sec24a/Sec22 分子名称: Protein transport protein Sec23A, Protein transport protein Sec24A, Vesicle-trafficking protein SEC22b, ... 著者 Ma, W, Goldberg, J. 登録日 2017-05-01 公開日 2017-07-05 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.905 Å) 主引用文献 ER retention is imposed by COPII protein sorting and attenuated by 4-phenylbutyrate. Elife, 6, 2017
4OUU	anti-MT1-MMP monoclonal antibody 分子名称: anti_MT1-MMP Heavy chain, anti_MT1-MMP light chain 著者 Udi, Y, Grossman, M, Solomonov, I, Dym, O, Rozenberg, H, Koziol, A, Cuniasse, P, Dive, V, Arroyo, A.G, Irit, S, Israel Structural Proteomics Center (ISPC) 登録日 2014-02-19 公開日 2014-12-17 最終更新日 2015-01-28 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Inhibition mechanism of membrane metalloprotease by an exosite-swiveling conformational antibody. Structure, 23, 2015
4OBA	Co-crystal structure of MDM2 with Inhibitor Compound 4 分子名称: E3 ubiquitin-protein ligase Mdm2, [(2R,5R,6R)-4-[(1S)-2-(tert-butylsulfonyl)-1-cyclopropylethyl]-6-(3-chlorophenyl)-5-(4-chlorophenyl)-3-oxomorpholin-2-yl]acetic acid 著者 Shaffer, P.L, Huang, X, Yakowec, P, Long, A.M. 登録日 2014-01-07 公開日 2014-03-19 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.602 Å) 主引用文献 Selective and Potent Morpholinone Inhibitors of the MDM2-p53 Protein-Protein Interaction. J.Med.Chem., 57, 2014
5Q0L	Ligand binding to FARNESOID-X-RECEPTOR 分子名称: (2S)-N,2-dicyclohexyl-2-{2-[4-(hydroxymethyl)phenyl]-1H-benzimidazol-1-yl}acetamide, Bile acid receptor, COACTIVATOR PEPTIDE SRC-1 HD3 著者 Rudolph, M.G, Benz, J, Burger, D, Thoma, R, Ruf, A, Joseph, C, Kuhn, B, Shao, C, Yang, H, Burley, S.K. 登録日 2017-05-31 公開日 2017-07-05 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 D3R Grand Challenge 2: blind prediction of protein-ligand poses, affinity rankings, and relative binding free energies. J. Comput. Aided Mol. Des., 32, 2018

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