2JZX
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![BU of 2jzx by Molmil](/molmil-images/mine/2jzx) | PCBP2 KH1-KH2 domains | 分子名称: | Poly(rC)-binding protein 2 | 著者 | Du, Z, Fenn, S, Tjhen, R, James, T. | 登録日 | 2008-01-21 | 公開日 | 2008-08-12 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of the first and second KH domains of human poly-C binding protein-2 reveals insights into its regulatory mechanisms To be Published
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2PC2
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![BU of 2pc2 by Molmil](/molmil-images/mine/2pc2) | Lysozyme Cocrystallized with Tris-dipicolinate Eu complex | 分子名称: | CHLORIDE ION, EUROPIUM ION, Lysozyme C, ... | 著者 | Pompidor, G, Vicat, J, Kahn, R. | 登録日 | 2007-03-29 | 公開日 | 2008-04-01 | 最終更新日 | 2017-10-18 | 実験手法 | X-RAY DIFFRACTION (1.538 Å) | 主引用文献 | A dipicolinate lanthanide complex for solving protein structures using anomalous diffraction Acta Crystallogr.,Sect.D, 66, 2010
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2JMN
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![BU of 2jmn by Molmil](/molmil-images/mine/2jmn) | NMR structure of human insulin mutant His-B10-Asp, Pro-B28-Lys, Lys-B29-Pro, 20 structures | 分子名称: | Insulin A chain, Insulin B chain | 著者 | Hua, Q.X, Hu, S.Q, Frank, B.H, Jia, W.H, Chu, Y.C, Wang, S.H, Burke, G.T, Katsoyannis, P.G, Weiss, M.A. | 登録日 | 2006-11-21 | 公開日 | 2006-12-05 | 最終更新日 | 2023-12-20 | 実験手法 | SOLUTION NMR | 主引用文献 | Mapping the functional surface of insulin by design: structure and function of a novel A-chain analogue. J.Mol.Biol., 264, 1996
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2OU7
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![BU of 2ou7 by Molmil](/molmil-images/mine/2ou7) | Structure of the Catalytic Domain of Human Polo-like Kinase 1 | 分子名称: | ACETATE ION, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | 著者 | Ding, Y.-H, Kothe, M, Kohls, D, Low, S. | 登録日 | 2007-02-09 | 公開日 | 2007-04-24 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure of the catalytic domain of human polo-like kinase 1. Biochemistry, 46, 2007
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2JMC
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![BU of 2jmc by Molmil](/molmil-images/mine/2jmc) | Chimer between Spc-SH3 and P41 | 分子名称: | Spectrin alpha chain, brain and P41 peptide chimera | 著者 | van Nuland, N.A.J, Candel, A.M, Martinez, J.C, Conejero-Lara, F, Bruix, M. | 登録日 | 2006-11-02 | 公開日 | 2007-04-24 | 最終更新日 | 2023-12-20 | 実験手法 | SOLUTION NMR | 主引用文献 | The high-resolution NMR structure of a single-chain chimeric protein mimicking a SH3-peptide complex Febs Lett., 581, 2007
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4LOO
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![BU of 4loo by Molmil](/molmil-images/mine/4loo) | Structural basis of autoactivation of p38 alpha induced by TAB1 (Monoclinic crystal form) | 分子名称: | 4-(4-FLUOROPHENYL)-1-(4-PIPERIDINYL)-5-(2-AMINO-4-PYRIMIDINYL)-IMIDAZOLE, Mitogen-activated protein kinase 14, TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 | 著者 | Chaikuad, A, DeNicola, G.F, Krojer, T, Allerston, C.K, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Marber, M.S, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2013-07-13 | 公開日 | 2013-08-21 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Mechanism and consequence of the autoactivation of p38 alpha mitogen-activated protein kinase promoted by TAB1. Nat.Struct.Mol.Biol., 20, 2013
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4LOQ
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![BU of 4loq by Molmil](/molmil-images/mine/4loq) | Structural basis of autoactivation of p38 alpha induced by TAB1 (Tetragonal crystal form with bound sulphate) | 分子名称: | 1,2-ETHANEDIOL, 4-(4-FLUOROPHENYL)-1-(4-PIPERIDINYL)-5-(2-AMINO-4-PYRIMIDINYL)-IMIDAZOLE, Mitogen-activated protein kinase 14, ... | 著者 | Chaikuad, A, DeNicola, G.F, Yue, W.W, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Marber, M.S, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2013-07-13 | 公開日 | 2013-08-21 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.319 Å) | 主引用文献 | Mechanism and consequence of the autoactivation of p38 alpha mitogen-activated protein kinase promoted by TAB1. Nat.Struct.Mol.Biol., 20, 2013
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2K3B
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2JGX
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![BU of 2jgx by Molmil](/molmil-images/mine/2jgx) | Structure of CCP module 7 of complement factor H - The AMD Not at risk varient (402Y) | 分子名称: | COMPLEMENT FACTOR H | 著者 | Herbert, A.P, Deakin, J.A, Schmidt, C.Q, Blaum, B.S, Egan, C, Ferreira, V.P, Pangburn, M.K, Lyon, M, Uhrin, D, Barlow, P.N. | 登録日 | 2007-02-16 | 公開日 | 2007-03-20 | 最終更新日 | 2018-05-02 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure shows that a glycosaminoglycan and protein recognition site in factor H is perturbed by age-related macular degeneration-linked single nucleotide polymorphism. J. Biol. Chem., 282, 2007
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2P45
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![BU of 2p45 by Molmil](/molmil-images/mine/2p45) | Complex of a camelid single-domain vhh antibody fragment with RNASE A at 1.1A resolution: SE5B-ORTHO-1 crystal form with five se-met sites (L4M, M34, M51, F68M, M83) in vhh scaffold. | 分子名称: | ANTIBODY CAB-RN05, Ribonuclease pancreatic, SULFATE ION | 著者 | Tereshko, V, Uysal, S, Koide, A, Margalef, K, Koide, S, Kossiakoff, A.A. | 登録日 | 2007-03-11 | 公開日 | 2008-03-11 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Toward chaperone-assisted crystallography: protein engineering enhancement of crystal packing and X-ray phasing capabilities of a camelid single-domain antibody (VHH) scaffold Protein Sci., 17, 2008
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2FGJ
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![BU of 2fgj by Molmil](/molmil-images/mine/2fgj) | Crystal structure of the ABC-cassette H662A mutant of HlyB with bound ATP | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Alpha-hemolysin translocation ATP-binding protein hlyB | 著者 | Zaitseva, J, Oswald, C, Jumpertz, T, Jenewein, S, Holland, I.B, Schmitt, L. | 登録日 | 2005-12-22 | 公開日 | 2006-08-08 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | A structural analysis of asymmetry required for catalytic activity of an ABC-ATPase domain dimer. Embo J., 25, 2006
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2OWB
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![BU of 2owb by Molmil](/molmil-images/mine/2owb) | Structure of the Catalytic Domain of Human Polo-like Kinase 1 | 分子名称: | 4-(4-METHYLPIPERAZIN-1-YL)-N-[5-(2-THIENYLACETYL)-1,5-DIHYDROPYRROLO[3,4-C]PYRAZOL-3-YL]BENZAMIDE, ACETATE ION, Serine/threonine-protein kinase PLK1, ... | 著者 | Ding, Y.-H, Kothe, M, Kohls, D, Low, S. | 登録日 | 2007-02-15 | 公開日 | 2007-04-24 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure of the catalytic domain of human polo-like kinase 1. Biochemistry, 46, 2007
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2FGV
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![BU of 2fgv by Molmil](/molmil-images/mine/2fgv) | X-ray crystal structure of HIV-1 Protease T80N variant in complex with the inhibitor saquinavir used to explore the role of invariant Thr80 in HIV-1 protease structure, function, and viral infectivity. | 分子名称: | (2S)-2-amino-3-phenylpropane-1,1-diol, 2-METHYL-DECAHYDRO-ISOQUINOLINE-3-CARBOXYLIC ACID, ASPARAGINE, ... | 著者 | Foulkes, J.E, Prabu-Jeyabalan, M, Cooper, D, Schiffer, C.A. | 登録日 | 2005-12-22 | 公開日 | 2006-11-07 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Role of invariant Thr80 in human immunodeficiency virus type 1 protease structure, function, and viral infectivity. J.Virol., 80, 2006
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2PB8
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![BU of 2pb8 by Molmil](/molmil-images/mine/2pb8) | Crystal structure of the complex formed between phospholipase A2 and peptide Ala-Val-Tyr-Ser at 2.0 A resolution | 分子名称: | ACETATE ION, AVYS, Phospholipase A2 VRV-PL-VIIIa | 著者 | Kumar, S, Singh, N, Sharma, S, Kaur, P, Singh, T.P. | 登録日 | 2007-03-28 | 公開日 | 2007-04-17 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of the complex formed between phospholipase A2 and peptide Ala-Val-Tyr-Ser at 2.0 A resolution To be Published
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2F80
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![BU of 2f80 by Molmil](/molmil-images/mine/2f80) | HIV-1 Protease mutant D30N complexed with inhibitor TMC114 | 分子名称: | (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, CHLORIDE ION, POL POLYPROTEIN, ... | 著者 | Kovalevsky, A.Y, Weber, I.T. | 登録日 | 2005-12-01 | 公開日 | 2006-03-07 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Effectiveness of Nonpeptide Clinical Inhibitor TMC-114 on HIV-1 Protease with Highly Drug Resistant Mutations D30N, I50V, and L90M. J.Med.Chem., 49, 2006
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2FA4
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2PE8
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2P3B
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![BU of 2p3b by Molmil](/molmil-images/mine/2p3b) | Crystal Structure of the subtype B wild type HIV protease complexed with TL-3 inhibitor | 分子名称: | benzyl [(1S,4S,7S,8R,9R,10S,13S,16S)-7,10-dibenzyl-8,9-dihydroxy-1,16-dimethyl-4,13-bis(1-methylethyl)-2,5,12,15,18-pentaoxo-20-phenyl-19-oxa-3,6,11,14,17-pentaazaicos-1-yl]carbamate, protease | 著者 | Sanches, M, Krauchenco, S, Martins, N.H, Gustchina, A, Wlodawer, A, Polikarpov, I. | 登録日 | 2007-03-08 | 公開日 | 2007-04-24 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural Characterization of B and non-B Subtypes of HIV-Protease: Insights into the Natural Susceptibility to Drug Resistance Development. J.Mol.Biol., 369, 2007
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2OSQ
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![BU of 2osq by Molmil](/molmil-images/mine/2osq) | NMR Structure of RRM-1 of Yeast NPL3 Protein | 分子名称: | Nucleolar protein 3 | 著者 | Deka, P, Bucheli, M, Skrisovska, L, Allain, F.H, Moore, C, Buratowski, S, Varani, G. | 登録日 | 2007-02-06 | 公開日 | 2007-12-18 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of the yeast SR protein Npl3 and Interaction with mRNA 3'-end processing signals. J.Mol.Biol., 375, 2008
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2EXE
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![BU of 2exe by Molmil](/molmil-images/mine/2exe) | Crystal structure of the phosphorylated CLK3 | 分子名称: | Dual specificity protein kinase CLK3 | 著者 | Papagrigoriou, E, Rellos, P, Das, S, Bullock, A, Ball, L.J, Turnbull, A, Savitsky, P, Fedorov, O, Johansson, C, Ugochukwu, E, Sobott, F, von Delft, F, Edwards, A, Sundstrom, M, Weigelt, J, Arrowsmith, C, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2005-11-08 | 公開日 | 2005-11-15 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Crystal structure of the phosphorylated CLK3 TO BE PUBLISHED
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2FGK
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![BU of 2fgk by Molmil](/molmil-images/mine/2fgk) | Crystal structure of the ABC-cassette E631Q mutant of HlyB with bound ATP | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Alpha-hemolysin translocation ATP-binding protein hlyB | 著者 | Zaitseva, J, Oswald, C, Jumpertz, T, Jenewein, S, Holland, I.B, Schmitt, L. | 登録日 | 2005-12-22 | 公開日 | 2006-08-08 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | A structural analysis of asymmetry required for catalytic activity of an ABC-ATPase domain dimer. Embo J., 25, 2006
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2MPF
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![BU of 2mpf by Molmil](/molmil-images/mine/2mpf) | Solution structure human HCN2 CNBD in the cAMP-unbound state | 分子名称: | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 | 著者 | Saponaro, A, Pauleta, S.R, Cantini, F, Matzapetakis, M, Hammann, C, Banci, L, Thiel, G, Santoro, B, Moroni, A. | 登録日 | 2014-05-16 | 公開日 | 2014-09-03 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural basis for the mutual antagonism of cAMP and TRIP8b in regulating HCN channel function. Proc.Natl.Acad.Sci.USA, 111, 2014
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2FGU
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![BU of 2fgu by Molmil](/molmil-images/mine/2fgu) | X-ray crystal structure of HIV-1 Protease T80S variant in complex with the inhibitor saquinavir used to explore the role of invariant Thr80 in HIV-1 protease structure, function, and viral infectivity. | 分子名称: | (2S)-2-amino-3-phenylpropane-1,1-diol, 2-METHYL-DECAHYDRO-ISOQUINOLINE-3-CARBOXYLIC ACID, ASPARAGINE, ... | 著者 | Foulkes, J.E, Prabu-Jeyabalan, M, Cooper, D, Schiffer, C.A. | 登録日 | 2005-12-22 | 公開日 | 2006-11-07 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Role of invariant Thr80 in human immunodeficiency virus type 1 protease structure, function, and viral infectivity. J.Virol., 80, 2006
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4LOP
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![BU of 4lop by Molmil](/molmil-images/mine/4lop) | Structural basis of autoactivation of p38 alpha induced by TAB1 (Tetragonal crystal form) | 分子名称: | 1,2-ETHANEDIOL, 4-(4-FLUOROPHENYL)-1-(4-PIPERIDINYL)-5-(2-AMINO-4-PYRIMIDINYL)-IMIDAZOLE, L(+)-TARTARIC ACID, ... | 著者 | Chaikuad, A, DeNicola, G.F, Krojer, T, Allerston, C.K, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Marber, M.S, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2013-07-13 | 公開日 | 2013-08-21 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.049 Å) | 主引用文献 | Mechanism and consequence of the autoactivation of p38 alpha mitogen-activated protein kinase promoted by TAB1. Nat.Struct.Mol.Biol., 20, 2013
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2N7G
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![BU of 2n7g by Molmil](/molmil-images/mine/2n7g) | |