8G3L
| BceAB-S nucleotide free BceS state 2 | 分子名称: | Bacitracin export ATP-binding protein BceA, Bacitracin export permease protein BceB, OLEIC ACID, ... | 著者 | George, N.L, Orlando, B.J. | 登録日 | 2023-02-08 | 公開日 | 2023-06-21 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Architecture of a complete Bce-type antimicrobial peptide resistance module. Nat Commun, 14, 2023
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8G3A
| BceAB-S nucleotide free TM state 1 | 分子名称: | Bacitracin export ATP-binding protein BceA, Bacitracin export permease protein BceB, OLEIC ACID, ... | 著者 | George, N.L, Orlando, B.J. | 登録日 | 2023-02-07 | 公開日 | 2023-06-21 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Architecture of a complete Bce-type antimicrobial peptide resistance module. Nat Commun, 14, 2023
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4JG7
| Structure of RSK2 CTD bound to 3-(3-(1H-pyrrolo[2,3-b]pyridine-3-carbonyl)phenyl)-2-cyanoacrylamide | 分子名称: | (2R)-2-cyano-3-[3-(1H-pyrrolo[2,3-b]pyridin-3-ylcarbonyl)phenyl]propanamide, Ribosomal protein S6 kinase alpha-3, SODIUM ION | 著者 | Miller, R.M, Paavilainen, V.O, Krishnan, S, Serafimova, I.M, Taunton, J. | 登録日 | 2013-02-28 | 公開日 | 2013-04-10 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.0002 Å) | 主引用文献 | Electrophilic fragment-based design of reversible covalent kinase inhibitors. J.Am.Chem.Soc., 135, 2013
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1O7U
| Radiation induced tryparedoxin-I | 分子名称: | TRYPAREDOXIN | 著者 | Alphey, M.S, Bond, C.S, McSweeney, S.M, Hunter, W.N. | 登録日 | 2002-11-14 | 公開日 | 2003-04-24 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Tryparedoxins from Crithidia Fasciculata and Trypanosoma Brucei: Photoreduction of the Redox Disulfide Using Synchrotron Radiation and Evidence for a Conformational Switch Implicated in Function J.Biol.Chem., 278, 2003
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8FRZ
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1O85
| Radiation-reduced Tryparedoxin-I | 分子名称: | TRYPAREDOXIN | 著者 | Alphey, M.S, Bond, C.S, Hunter, W.N. | 登録日 | 2002-11-25 | 公開日 | 2003-04-24 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Tryparedoxins from Crithidia Fasciculata and Trypanosoma Brucei: Photoreduction of the Redox Disulfide Using Synchrotron Radiation and Evidence for a Conformational Switch Implicated in Function J.Biol.Chem., 278, 2003
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8FSB
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8FSP
| Full-length mouse 5-HT3A receptor in complex with SMP100, open-like | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-[(1R,3S,4R)-1-azabicyclo[2.2.2]octan-3-yl]-1,3,4,5-tetrahydro-6H-azepino[5,4,3-cd]indazol-6-one, 5-hydroxytryptamine receptor 3A | 著者 | Felt, K.C, Chakrapani, S. | 登録日 | 2023-01-10 | 公開日 | 2023-12-27 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.79 Å) | 主引用文献 | Structural basis for partial agonism in 5-HT 3A receptors. Nat.Struct.Mol.Biol., 31, 2024
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1OC8
| TRYPAREDOXIN II FROM C.FASCICULATA SOLVED BY MR | 分子名称: | SULFATE ION, TRYPAREDOXIN II | 著者 | Leonard, G.A, Micossi, E, Hunter, W.N. | 登録日 | 2003-02-07 | 公開日 | 2003-04-02 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Tryparedoxins from Crithidia Fasciculata and Trypanosoma Brucei: Photoreduction of the Redox Disulfide Using Synchrotron Radiation and Evidence for a Conformational Switch Implicated in Function J.Biol.Chem., 278, 2003
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8FRJ
| Structure of nsp14 N7-MethylTransferase domain fused with TELSAM bound to SGC0946 | 分子名称: | 5-bromo-7-{5-[(3-{[(4-tert-butylphenyl)carbamoyl]amino}propyl)(propan-2-yl)amino]-5-deoxy-beta-D-ribofuranosyl}-7H-pyrrolo[2,3-d]pyrimidin-4-amine, Transcription factor ETV6,Guanine-N7 methyltransferase nsp14 chimera, ZINC ION | 著者 | Kottur, J, Aggarwal, A.K. | 登録日 | 2023-01-07 | 公開日 | 2023-07-26 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | 主引用文献 | Structures of SARS-CoV-2 N7-methyltransferase with DOT1L and PRMT7 inhibitors provide a platform for new antivirals. Plos Pathog., 19, 2023
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1LAI
| Solution Structure of the B-DNA Duplex CGCGGTGTCCGCG. | 分子名称: | 5'-D(*CP*GP*CP*GP*GP*AP*CP*AP*CP*CP*GP*CP*G)-3', 5'-D(*CP*GP*CP*GP*GP*TP*GP*TP*CP*CP*GP*CP*G)-3' | 著者 | Weisenseel, J.P, Reddy, G.R, Marnett, L.J, Stone, M.P. | 登録日 | 2002-03-28 | 公開日 | 2002-04-17 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of an oligodeoxynucleotide containing a 1,N(2)-propanodeoxyguanosine adduct positioned in a palindrome derived from the Salmonella typhimurium hisD3052 gene: Hoogsteen pairing at pH 5.2. Chem.Res.Toxicol., 15, 2002
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4HGF
| Crystal structure of P450 BM3 5F5K heme domain variant complexed with styrene | 分子名称: | Bifunctional P-450/NADPH-P450 reductase, CHLORIDE ION, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Shehzad, A, Panneerselvam, S, Bocola, M, Mueller-Dieckmann, J, Wilmanns, M, Schwaneberg, U. | 登録日 | 2012-10-08 | 公開日 | 2013-05-01 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | P450 BM3 crystal structures reveal the role of the charged surface residue Lys/Arg184 in inversion of enantioselective styrene epoxidation. Chem.Commun.(Camb.), 49, 2013
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1OOG
| Complex of Drosophila odorant binding protein LUSH with propanol | 分子名称: | ACETATE ION, N-PROPANOL, odorant binding protein LUSH | 著者 | Kruse, S.W, Zhao, R, Smith, D.P, Jones, D.N.M. | 登録日 | 2003-03-03 | 公開日 | 2003-09-02 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Structure of a specific alcohol-binding site defined by the odorant binding protein LUSH from Drosophila melanogaster Nat.Struct.Biol., 10, 2003
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1XH5
| Crystal Structures of Protein Kinase B Selective Inhibitors in Complex with Protein Kinase A and Mutants | 分子名称: | (R,R)-2,3-BUTANEDIOL, N-{4-[(4-{3-[(2R)-3,3-DIMETHYLPIPERIDIN-2-YL]-2-FLUORO-6-HYDROXYBENZOYL}BENZOYL)AMINO]AZEPAN-3-YL}ISONICOTINAMIDE, cAMP-dependent protein kinase inhibitor, ... | 著者 | Breitenlechner, C.B, Friebe, W.-G, Brunet, E, Werner, G, Graul, K, Thomas, U, Kuenkele, K.-P, Schaefer, W, Gassel, M, Bossemeyer, D, Huber, R, Engh, R.A, Masjost, B. | 登録日 | 2004-09-17 | 公開日 | 2005-09-17 | 最終更新日 | 2024-06-26 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Design and crystal structures of protein kinase B-selective inhibitors in complex with protein kinase A and mutants J.Med.Chem., 48, 2005
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4GUW
| Crystal structure of type 1 Ribosome inactivating protein from Momordica balsamina with lipopolysaccharide at 1.6 Angstrom resolution | 分子名称: | (R)-((2R,3S,4R,5R,6R)-3-HYDROXY-2-(HYDROXYMETHYL)-5-((R)-3-HYDROXYTETRADECANAMIDO)-6-(PHOSPHONOOXY)TETRAHYDRO-2H-PYRAN-4-YL) 3-HYDROXYTETRADECANOATE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ... | 著者 | Singh, A, Pandey, S, Kushwaha, G.S, Bhushan, A, Sinha, M, Kaur, P, Sharma, S, Singh, T.P. | 登録日 | 2012-08-30 | 公開日 | 2012-09-12 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystal structure of type 1 Ribosome inactivating protein from Momordica balsamina with lipopolysaccharide at 1.6 Angstrom resolution To be published
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7O1H
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1XH4
| Crystal Structures of Protein Kinase B Selective Inhibitors in Complex with Protein Kinase A and Mutants | 分子名称: | N-[4-({4-[5-(DIMETHYLAMINO)-2-HYDROXYBENZOYL]BENZOYL}AMINO)AZEPAN-3-YL]ISONICOTINAMIDE, cAMP-dependent protein kinase inhibitor, alpha form, ... | 著者 | Breitenlechner, C.B, Friebe, W.-G, Brunet, E, Werner, G, Graul, K, Thomas, U, Kuenkele, K.-P, Schaefer, W, Gassel, M, Bossemeyer, D, Huber, R, Engh, R.A, Masjost, B. | 登録日 | 2004-09-17 | 公開日 | 2005-09-17 | 最終更新日 | 2024-06-26 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Design and crystal structures of protein kinase B-selective inhibitors in complex with protein kinase A and mutants J.Med.Chem., 48, 2005
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5XC1
| Crystal structure of the complex of an aromatic mutant (W6A) of an alkali thermostable GH10 Xylanase from Bacillus sp. NG-27 with S-1,2-Propanediol | 分子名称: | Beta-xylanase, MAGNESIUM ION, S-1,2-PROPANEDIOL, ... | 著者 | Bansia, H, Mahanta, P, Ramakumar, S. | 登録日 | 2017-03-21 | 公開日 | 2018-03-28 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | 主引用文献 | Small Glycols Discover Cryptic Pockets on Proteins for Fragment-Based Approaches. J.Chem.Inf.Model., 2021
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5U4T
| Crystal structure of a methyltransferase involved in the biosynthesis of gentamicin | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, IODIDE ION, Putative gentamicin methyltransferase, ... | 著者 | Bury, P, Huang, F, Leadlay, P, Dias, M.V.B. | 登録日 | 2016-12-06 | 公開日 | 2017-11-01 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.086 Å) | 主引用文献 | Structural Basis of the Selectivity of GenN, an Aminoglycoside N-Methyltransferase Involved in Gentamicin Biosynthesis. ACS Chem. Biol., 12, 2017
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8EQZ
| Crystal structure of pregnane X receptor ligand binding domain complexed with T0901317 analog T0-C6 | 分子名称: | N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-hexylbenzenesulfonamide, Nuclear receptor subfamily 1 group I member 2 | 著者 | Huber, A.D, Poudel, S, Seetharaman, J, Miller, D.J, Lin, W, Li, Y, Chen, T. | 登録日 | 2022-10-11 | 公開日 | 2023-03-15 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | 主引用文献 | Structure-guided approach to modulate small molecule binding to a promiscuous ligand-activated protein. Proc.Natl.Acad.Sci.USA, 120, 2023
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6ZE0
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7A47
| KRASG12C GDP form in complex with Cpd4 | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Isoform 2B of GTPase KRas, ~{N}-[3-bromanyl-2-(2-methylimidazol-1-yl)pyridin-4-yl]-3-[[3-bromanyl-2-(2-methylimidazol-1-yl)pyridin-4-yl]-propanoyl-amino]propanamide | 著者 | Bertrand, T, Steier, V. | 登録日 | 2020-08-19 | 公開日 | 2021-10-13 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | 主引用文献 | KRAS G12C fragment screening renders new binding pockets. Small Gtpases, 13, 2022
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3SGD
| Crystal structure of the mouse mAb 17.2 | 分子名称: | CALCIUM ION, Heavy Chain, Light Chain | 著者 | Pizarro, J.C, Boulot, G, Hontebeyrie, M, Bentley, G.A. | 登録日 | 2011-06-14 | 公開日 | 2011-11-09 | 最終更新日 | 2013-01-23 | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | 主引用文献 | Crystal structure of the complex mAb 17.2 and the C-terminal region of Trypanosoma cruzi P2 Beta protein: implications in cross-reactivity Plos Negl Trop Dis, 5, 2011
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4H51
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7RMA
| Structure of the fourth UIM (Ubiquitin Interacting Motif) of ANKRD13D in complex with a high affinity UbV (Ubiquitin Variant) | 分子名称: | Ankyrin repeat domain-containing protein 13D, SODIUM ION, SULFATE ION, ... | 著者 | Singer, A.U, Manczyk, N, Veggiani, G, Sicheri, F, Sidhu, S.S. | 登録日 | 2021-07-27 | 公開日 | 2022-05-11 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Panel of Engineered Ubiquitin Variants Targeting the Family of Human Ubiquitin Interacting Motifs. Acs Chem.Biol., 17, 2022
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