PDB: 45953 件ウェブページステータス検索Chemie searchBIRD

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2WGX	HUMAN P53 CORE DOMAIN MUTANT M133L-V203A-Y236F-N239Y-T253I-N268D 分子名称: CELLULAR TUMOR ANTIGEN P53, ZINC ION 著者 Joerger, A.C, Khoo, K.H, Fersht, A.R. 登録日 2009-04-27 公開日 2009-05-12 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Stabilising the DNA-Binding Domain of P53 by Rational Design of its Hydrophobic Core. Protein Eng.Des.Sel., 22, 2009
8D96	Human DNA polymerase alpha/primase elongation complex I bound to primer/template 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*AP*TP*AP*AP*TP*GP*GP*TP*CP*GP*TP*GP*CP*CP*GP*CP*CP*AP*AP*TP*AP*A)-3'), DNA polymerase alpha catalytic subunit, ... 著者 He, Q, Baranovskiy, A, Lim, C, Tahirov, T. 登録日 2022-06-09 公開日 2023-04-19 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.35 Å) 主引用文献 Structures of human primosome elongation complexes. Nat.Struct.Mol.Biol., 30, 2023
7XLJ	The crystal structure of ORE1(ANAC092) NAC domain 分子名称: NAC domain-containing protein 92 著者 Chun, I.S, Kim, M.S. 登録日 2022-04-21 公開日 2023-03-29 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Structural basis of DNA binding by the NAC transcription factor ORE1, a master regulator of plant senescence. Plant Commun., 4, 2023
7SR6	Human Endogenous Retrovirus (HERV-K) reverse transcriptase ternary complex with dsDNA template Primer and dNTP 分子名称: 1,2-ETHANEDIOL, 1,4-DIETHYLENE DIOXIDE, 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, ... 著者 Baldwin, E.T, Nichols, C. 登録日 2021-11-08 公開日 2022-07-20 実験手法 X-RAY DIFFRACTION (2.62 Å) 主引用文献 Human endogenous retrovirus-K (HERV-K) reverse transcriptase (RT) structure and biochemistry reveals remarkable similarities to HIV-1 RT and opportunities for HERV-K-specific inhibition. Proc.Natl.Acad.Sci.USA, 119, 2022
8K89	Crystal structure of NFIL3 分子名称: Nuclear factor interleukin-3-regulated protein 著者 Min, J.R, Chen, S.Z, Liu, K. 登録日 2023-07-29 公開日 2024-03-06 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural basis for specific DNA sequence recognition by the transcription factor NFIL3. J.Biol.Chem., 300, 2024
4Y5U	Transcription factor 分子名称: NICKEL (II) ION, Signal transducer and activator of transcription 6 著者 Li, J, Niu, F, Ouyang, S, Liu, Z. 登録日 2015-02-12 公開日 2016-02-17 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.708 Å) 主引用文献 Structural basis for DNA recognition by STAT6 Proc.Natl.Acad.Sci.USA, 113, 2016
7UFM	VchTnsC AAA+ with DNA (double heptamer) 分子名称: ADENOSINE-5'-TRIPHOSPHATE, DNA (36-MER), VchTnsC 著者 Fernandez, I.S, Sternberg, S.H. 登録日 2022-03-22 公開日 2022-06-08 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Selective TnsC recruitment enhances the fidelity of RNA-guided transposition. Nature, 609, 2022
3C95	Exonuclease I (apo) 分子名称: Exodeoxyribonuclease I, MAGNESIUM ION 著者 Keck, J.L, Lu, D. 登録日 2008-02-15 公開日 2008-07-08 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural basis of Escherichia coli single-stranded DNA-binding protein stimulation of exonuclease I. Proc.Natl.Acad.Sci.USA, 105, 2008
1CO0	NMR STUDY OF TRP REPRESSOR-MTR OPERATOR DNA COMPLEX 分子名称: 5'-D(*TP*GP*TP*AP*CP*CP*AP*GP*TP*AP*CP*AP*CP*GP*AP*GP*TP*AP*CP*A)-3', 5'-D(*TP*GP*TP*AP*CP*TP*CP*GP*TP*GP*TP*AP*CP*TP*GP*GP*TP*AP*CP*A)-3', TRP OPERON REPRESSOR, ... 著者 Zhou, G.P, Brocchieri, L, Jardetzky, O. 登録日 1999-05-30 公開日 2003-09-16 最終更新日 2023-12-27 実験手法 SOLUTION NMR 主引用文献 Allostery and Induced Fit, NMR and Molecular Modeling Study of the trp-repressor - mtr DNA complex Structures and Mechanisms, ACS Symposium Series, 827, 2002
7JM4	IRF Transcription Factor 分子名称: Interferon regulatory factor 4, Interferon-Stimulated Response Elements 著者 Sundararaj, S, Williams, S.J, Casarotto, M.G. 登録日 2020-07-31 公開日 2021-03-24 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Structural determinants of the IRF4/DNA homodimeric complex. Nucleic Acids Res., 49, 2021
5MG8	Crystal structure of the S.pombe Smc5/6 hinge domain 分子名称: GLYCEROL, SULFATE ION, Structural maintenance of chromosomes protein 5, ... 著者 Alt, A, Pearl, L.H, Oliver, A.W. 登録日 2016-11-21 公開日 2017-02-08 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Specialized interfaces of Smc5/6 control hinge stability and DNA association. Nat Commun, 8, 2017
6YN1	Crystal structure of histone chaperone APLF acidic domain bound to the histone H2A-H2B-H3-H4 octamer 分子名称: Aprataxin and PNK-like factor, CHLORIDE ION, GLYCEROL, ... 著者 Corbeski, I, Guo, X, Van Ingen, H, Sixma, T.K. 登録日 2020-04-10 公開日 2021-11-17 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Chaperoning of the histone octamer by the acidic domain of DNA repair factor APLF. Sci Adv, 8, 2022
8J8N	Structure of p53 DNA-binding domain and ZNF568 KRAB domain complex 分子名称: Cellular tumor antigen p53, ZINC ION, Zinc finger protein 568 著者 Han, C.W. 登録日 2023-05-02 公開日 2024-05-15 実験手法 ELECTRON MICROSCOPY (9.02 Å) 主引用文献 Structure of p53 DNA-binding domain and ZNF568 KRAB domain complex To Be Published
4ZZL	MexR R21W derepressor mutant causing multidrug resistance in P. aeruginosa by mexAB-oprM efflux pump expression 分子名称: GLYCEROL, MULTIDRUG RESISTANCE OPERON REPRESSOR 著者 Anandapadamanaban, M, Pilstal, R, Ziauddin, J.M.E, Moche, M, Wallner, B, Sunnerhagen, M. 登録日 2015-04-10 公開日 2016-07-27 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.19 Å) 主引用文献 Mutation-Induced Population Shift in the Mexr Conformational Ensemble Disengages DNA Binding: A Novel Mechanism for Marr Family Derepression. Structure, 24, 2016
6NVZ	NMR Structure of the DNA binding domain of EhMybS3 分子名称: Myb family DNA-binding protein shaqkyf family 著者 Titaux-Delgado, G.A, del Rio-Portilla, f. 登録日 2019-02-05 公開日 2020-02-12 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Genome-wide and structural analysis of the Myb-SHAQKYF family in Entamoeba histolytica. Biochim Biophys Acta Proteins Proteom, 1869, 2021
5BOM	DNA polymerase beta binary complex with a templating 5ClC 分子名称: DNA (5'-D(*CP*CP*GP*AP*CP*(4U3)P*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ... 著者 Freudenthal, B.D, Wilson, S.H. 登録日 2015-05-27 公開日 2015-08-19 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.0002 Å) 主引用文献 Intrinsic mutagenic properties of 5-chlorocytosine: A mechanistic connection between chronic inflammation and cancer. Proc.Natl.Acad.Sci.USA, 112, 2015
6G2Q	Ternary complex crystal structure of DNA polymerase Beta with a dideoxy terminated primer with CHCL (S-isomer), beta, gamma dTTP analogue 分子名称: CHLORIDE ION, DNA polymerase beta, Downstream Primer Strand, ... 著者 Batra, V.K, Wilson, S.H. 登録日 2018-03-23 公開日 2018-07-04 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.148 Å) 主引用文献 Mapping Functional Substrate-Enzyme Interactions in the pol beta Active Site through Chemical Biology: Structural Responses to Acidity Modification of Incoming dNTPs. Biochemistry, 57, 2018
4RT3	Ternary complex crystal structure of DNA polymerase Beta with (alpha, beta)-NH-(beta,gamma)-CH2-dTTP 分子名称: 2'-deoxy-5'-O-[(S)-hydroxy{[(R)-hydroxy(phosphonomethyl)phosphoryl]amino}phosphoryl]-3,4-dihydrothymidine, CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*CP*AP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ... 著者 Batra, V.K, Wilson, S.H. 登録日 2014-11-12 公開日 2015-07-01 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Two Scaffolds from Two Flips: (alpha, beta)/(beta, gamma) CH2/NH "Met-Im" Analogues of dTTP. Org.Lett., 17, 2015
3M8K	Protein structure of type III plasmid segregation TubZ 分子名称: FtsZ/tubulin-related protein 著者 Schumacher, M.A, Ni, L. 登録日 2010-03-18 公開日 2010-07-07 最終更新日 2017-11-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 From the Cover: Plasmid protein TubR uses a distinct mode of HTH-DNA binding and recruits the prokaryotic tubulin homolog TubZ to effect DNA partition. Proc.Natl.Acad.Sci.USA, 107, 2010
1JEQ	Crystal Structure of the Ku Heterodimer 分子名称: KU70, KU80 著者 Walker, J.R, Corpina, R.A, Goldberg, J. 登録日 2001-06-18 公開日 2001-08-15 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structure of the Ku heterodimer bound to DNA and its implications for double-strand break repair. Nature, 412, 2001
4RT2	Ternary complex crystal structure of DNA polymerase Beta with (alpha,beta)-CH2-(beta,gamma)-NH-dTTP 分子名称: 2'-deoxy-5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonoamino)phosphoryl]methyl}phosphoryl]-3,4-dihydrothymidine, CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*CP*AP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ... 著者 Batra, V.K, Wilson, S.H. 登録日 2014-11-12 公開日 2015-07-01 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Two Scaffolds from Two Flips: (alpha, beta)/(beta, gamma) CH2/NH "Met-Im" Analogues of dTTP. Org.Lett., 17, 2015
4NMN	Aquifex aeolicus replicative helicase (DnaB) complexed with ADP, at 3.3 resolution 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Replicative DNA helicase, ... 著者 Lyubimov, A.Y, Strycharska, M.S, Erzberger, J.P, Berger, J.M. 登録日 2013-11-15 公開日 2014-01-29 実験手法 X-RAY DIFFRACTION (3.301 Å) 主引用文献 Nucleotide and partner-protein control of bacterial replicative helicase structure and function. Mol.Cell, 52, 2013
4EOT	Crystal structure of the MafA homodimer bound to the consensus MARE 分子名称: 5'-D(*CP*CP*CP*TP*GP*CP*TP*GP*AP*CP*TP*CP*AP*GP*CP*AP*CP*CP*G)-3', 5'-D(*CP*CP*GP*GP*TP*GP*CP*TP*GP*AP*GP*TP*CP*AP*GP*CP*AP*GP*G)-3', SULFATE ION, ... 著者 Lu, X, Guanga, G, Wan, C, Rose, R.B. 登録日 2012-04-15 公開日 2012-11-28 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.855 Å) 主引用文献 A Novel DNA Binding Mechanism for maf Basic Region-Leucine Zipper Factors Inferred from a MafA-DNA Complex Structure and Binding Specificities. Biochemistry, 51, 2012
2L0K	NMR solution structure of a transcription factor SpoIIID in complex with DNA 分子名称: Stage III sporulation protein D 著者 Chen, B, Himes, P, Lu, Z, Liu, A, Yan, H, Kroos, L. 登録日 2010-07-08 公開日 2011-08-17 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Novel Mode of DNA Binding by Bacterial Transcription Factor SpoIIID To be Published
3PX0	Crystal Structure of Bacillus DNA Polymerase I Large Fragment Bound to DNA and dCTP-dA Mismatch (tautomer) in Closed Conformation 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*C*AP*TP*AP*GP*GP*AP*GP*TP*CP*AP*GP*G)-3'), DNA (5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*(DOC))-3'), ... 著者 Wang, W, Beese, L.S. 登録日 2010-12-09 公開日 2011-10-19 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Structural evidence for the rare tautomer hypothesis of spontaneous mutagenesis. Proc.Natl.Acad.Sci.USA, 108, 2011

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