4XD4
 
 | | Phosphotriesterase variant E2b | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CACODYLATE ION, Phosphotriesterase variant PTE-R3, ... | | 著者 | Jackson, C.J, Campbell, E, Kaltenbach, M, Tokuriki, N. | | 登録日 | 2014-12-19 | | 公開日 | 2015-12-23 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The role of protein dynamics in the evolution of new enzyme function.
Nat.Chem.Biol., 12, 2016
|
|
4XF5
 | | Crystal structure of a TRAP periplasmic solute binding protein from Chromohalobacter salexigens DSM 3043 (Csal_0678), Target EFI-501078, with bound (S)-(+)-2-Amino-1-propanol. | | 分子名称: | (2S)-2-aminopropan-1-ol, CHLORIDE ION, Twin-arginine translocation pathway signal | | 著者 | Vetting, M.W, Al Obaidi, N.F, Toro, R, Morisco, L.L, Benach, J, Wasserman, S.R, Attonito, J.D, Scott Glenn, A, Chamala, S, Chowdhury, S, Lafleur, J, Love, J, Seidel, R.D, Whalen, K.L, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | | 登録日 | 2014-12-26 | | 公開日 | 2015-01-28 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Crystal structure of a TRAP periplasmic solute binding protein from Chromohalobacter salexigens DSM 3043 (Csal_0678), Target EFI-501078, with bound (S)-(+)-2-Amino-1-propanol.
To be published
|
|
4XFZ
 | | Structure of the native full-length HIV-1 capsid protein in complex with PF-3450074 (PF74) | | 分子名称: | CHLORIDE ION, HIV-1 capsid protein, IODIDE ION, ... | | 著者 | Gres, A.T, Kirby, K.A, Sarafianos, S.G. | | 登録日 | 2014-12-29 | | 公開日 | 2015-06-10 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | STRUCTURAL VIROLOGY. X-ray crystal structures of native HIV-1 capsid protein reveal conformational variability.
Science, 349, 2015
|
|
5ZYL
 | | Crystal structure of CERT START domain in complex with compound E25A | | 分子名称: | 2-[4-[4-cyclopentyl-3-[(1~{S},2~{R})-2-pyridin-2-ylcyclopropyl]phenyl]phenyl]sulfonylethanol, GLYCEROL, LIPID-TRANSFER PROTEIN CERT | | 著者 | Suzuki, M, Nakao, N, Ueno, M, Sakai, S, Egawa, D, Hanzawa, H, Kawasaki, S, Kumagai, K, Kobayashi, S, Hanada, K. | | 登録日 | 2018-05-25 | | 公開日 | 2019-02-27 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Natural ligand-nonmimetic inhibitors of the lipid-transfer protein CERT
Commun Chem, 2019
|
|
4XOP
 | | Tailspike protein double mutant D339N/E372Q of E. coli bacteriophage HK620 in complex with hexasaccharide | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FORMIC ACID, SODIUM ION, ... | | 著者 | Gohlke, U, Broeker, N.K, Heinemann, U, Seckler, R, Barbirz, S. | | 登録日 | 2015-01-16 | | 公開日 | 2016-01-27 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | | 主引用文献 | Enthalpic cost of water removal from a hydrophobic glucose binding cavity on HK620 tailspike protein.
to be published
|
|
6A4R
 | | Crystal structure of aspartate bound peptidase E from Salmonella enterica | | 分子名称: | ASPARTIC ACID, Peptidase E | | 著者 | Yadav, P, Chandravanshi, K, Goyal, V.D, Singh, R, Kumar, A, Gokhale, S.M, Makde, R.D. | | 登録日 | 2018-06-20 | | 公開日 | 2018-10-24 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.828 Å) | | 主引用文献 | Structure of Asp-bound peptidase E from Salmonella enterica: Active site at dimer interface illuminates Asp recognition.
FEBS Lett., 592, 2018
|
|
6A52
 | | Oxidase ChaP-H1 | | 分子名称: | FE (II) ION, dioxidase ChaP-H1 | | 著者 | Zhang, B, Ge, H.M. | | 登録日 | 2018-06-21 | | 公開日 | 2018-08-29 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Molecular Basis for the Final Oxidative Rearrangement Steps in Chartreusin Biosynthesis.
J. Am. Chem. Soc., 140, 2018
|
|
6A5W
 | | FXR-LBD with HNC143 and SRC1 | | 分子名称: | 2-[2-[[3-[2,6-bis(chloranyl)phenyl]-5-cyclopropyl-1,2-oxazol-4-yl]methoxy]-6-azaspiro[3.4]octan-6-yl]-1,3-benzothiazole-6-carboxylic acid, Bile acid receptor, Nuclear receptor coactivator 1 | | 著者 | Wang, N, Liu, J. | | 登録日 | 2018-06-25 | | 公開日 | 2018-10-10 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.88 Å) | | 主引用文献 | Ligand binding and heterodimerization with retinoid X receptor alpha (RXR alpha ) induce farnesoid X receptor (FXR) conformational changes affecting coactivator binding
J. Biol. Chem., 293, 2018
|
|
6A8M
 | | N-terminal domain of FACT complex subunit SPT16 from Eremothecium gossypii (Ashbya gossypii) | | 分子名称: | FACT complex subunit SPT16 | | 著者 | Gaur, N.K, Are, V.N, Durani, V, Ghosh, B, Kumar, A, Kulkarni, K, Makde, R.D. | | 登録日 | 2018-07-09 | | 公開日 | 2018-08-15 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Evolutionary conservation of protein dynamics: insights from all-atom molecular dynamics simulations of 'peptidase' domain of Spt16.
J.Biomol.Struct.Dyn., 2021
|
|
6A17
 | | Crystal structure of CYP90B1 in complex with brassinazole | | 分子名称: | (2R,3S)-4-(4-chlorophenyl)-2-phenyl-3-(1H-1,2,4-triazol-1-yl)butan-2-ol, CHLORIDE ION, Cytochrome P450 90B1, ... | | 著者 | Fujiyama, K, Hino, T, Kanadani, M, Mizutani, M, Nagano, S. | | 登録日 | 2018-06-06 | | 公開日 | 2019-06-12 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.301 Å) | | 主引用文献 | Structural insights into a key step of brassinosteroid biosynthesis and its inhibition.
Nat.Plants, 5, 2019
|
|
4ZQA
 | |
4ZQK
 | | Structure of the complex of human programmed death-1 (PD-1) and its ligand PD-L1. | | 分子名称: | Programmed cell death 1 ligand 1, Programmed cell death protein 1, SODIUM ION | | 著者 | Zak, K.M, Dubin, G, Holak, T.A. | | 登録日 | 2015-05-10 | | 公開日 | 2015-11-04 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Structure of the Complex of Human Programmed Death 1, PD-1, and Its Ligand PD-L1.
Structure, 23, 2015
|
|
5ZQQ
 | | Tankyrase-2 in complex with compound 52 | | 分子名称: | 1-methyl-1'-(4-oxo-3,4,5,6,7,8-hexahydroquinazolin-2-yl)spiro[indole-3,4'-piperidin]-2(1H)-one, GLYCEROL, PHOSPHATE ION, ... | | 著者 | Niwa, H, Shirai, F, Sato, S, Yoshimoto, N, Tsumura, T, Okue, M, Shirouzu, M, Seimiya, H, Umehara, T. | | 登録日 | 2018-04-19 | | 公開日 | 2019-04-03 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | | 主引用文献 | Discovery of Novel Spiroindoline Derivatives as Selective Tankyrase Inhibitors.
J. Med. Chem., 62, 2019
|
|
5ZS3
 | | Small heat shock protein from M. marinum:Form-1 | | 分子名称: | CHLORIDE ION, GLY-ARG-LEU-LEU-PRO, Molecular chaperone (Small heat shock protein), ... | | 著者 | Bhandari, S, Suguna, K. | | 登録日 | 2018-04-27 | | 公開日 | 2019-01-30 | | 最終更新日 | 2019-04-17 | | 実験手法 | X-RAY DIFFRACTION (2.001 Å) | | 主引用文献 | Dodecameric structure of a small heat shock protein from Mycobacterium marinum M.
Proteins, 87, 2019
|
|
4ZD3
 | | Structure of a transglutaminase 2-specific autoantibody Fab fragment | | 分子名称: | 679-14-14E06 Fab fragment heavy chain, 679-14-14E06 Fab fragment light chain | | 著者 | Chen, X, Dalhus, B, Hnida, K, Iversen, R, Sollid, L.M. | | 登録日 | 2015-04-16 | | 公開日 | 2015-07-22 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural Basis for Antigen Recognition by Transglutaminase 2-specific Autoantibodies in Celiac Disease.
J.Biol.Chem., 290, 2015
|
|
6A5F
 | |
4YXB
 | | FliM(SPOA)::FliN fusion protein | | 分子名称: | Ambiguous peptide density, Flagellar motor switch protein FliM,Flagellar motor switch protein FliN, FliM::FliN fragment, ... | | 著者 | Notti, R.Q, Stebbins, C.E. | | 登録日 | 2015-03-22 | | 公開日 | 2015-06-03 | | 最終更新日 | 2017-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.56 Å) | | 主引用文献 | A common assembly module in injectisome and flagellar type III secretion sorting platforms.
Nat Commun, 6, 2015
|
|
4ZE1
 | | Saccharomyces cerevisiae CYP51 Y140F mutant complexed with posaconazole in the active site | | 分子名称: | Lanosterol 14-alpha demethylase, POSACONAZOLE, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Sagatova, A, Keniya, M.V, Wilson, R, Tyndall, J.D.A, Monk, B.C. | | 登録日 | 2015-04-20 | | 公開日 | 2016-03-30 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Triazole resistance mediated by mutations of a conserved active site tyrosine in fungal lanosterol 14 alpha-demethylase.
Sci Rep, 6, 2016
|
|
5ZS6
 | |
4YXV
 | |
4YZB
 | |
4YZP
 | |
5ZSM
 | | Crystal structure of monkey TLR7 in complex with GGUCCC | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-amino-9-[(2S,3aR,4R,6R,6aR)-2-hydroxy-6-(hydroxymethyl)-2-oxotetrahydro-2H-2lambda~5~-furo[3,4-d][1,3,2]dioxaphosphol-4-yl]-3,9-dihydro-6H-purin-6-one, ... | | 著者 | Zhang, Z, Ohto, U, Shimizu, T. | | 登録日 | 2018-04-28 | | 公開日 | 2019-01-30 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural Analyses of Toll-like Receptor 7 Reveal Detailed RNA Sequence Specificity and Recognition Mechanism of Agonistic Ligands.
Cell Rep, 25, 2018
|
|
4Z26
 | | Mimivirus R135 (residues 51-702) | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Putative GMC-type oxidoreductase R135 | | 著者 | Klose, T, Rossmann, M.G. | | 登録日 | 2015-03-28 | | 公開日 | 2015-05-13 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.915 Å) | | 主引用文献 | A Mimivirus Enzyme that Participates in Viral Entry.
Structure, 23, 2015
|
|
5ZVP
 | |
