5ZYL

Crystal structure of CERT START domain in complex with compound E25A

Summary for 5ZYL

Entry DOI	10.2210/pdb5zyl/pdb
Related	5ZYG 5ZYH 5ZYI 5ZYJ 5ZYK 5ZYM
Descriptor	LIPID-TRANSFER PROTEIN CERT, 2-[4-[4-cyclopentyl-3-[(1~{S},2~{R})-2-pyridin-2-ylcyclopropyl]phenyl]phenyl]sulfonylethanol, GLYCEROL, ... (4 entities in total)
Functional Keywords	cert, ph, start, complex, lipid transport
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	27596.46
Authors	Suzuki, M.,Nakao, N.,Ueno, M.,Sakai, S.,Egawa, D.,Hanzawa, H.,Kawasaki, S.,Kumagai, K.,Kobayashi, S.,Hanada, K. (deposition date: 2018-05-25, release date: 2019-02-27, Last modification date: 2024-03-27)
Primary citation	Nakao, N.,Ueno, M.,Sakai, S.,Egawa, D.,Hanzawa, H.,Kawasaki, S.,Kumagai, K.,Suzuki, M.,Kobayashi, S.,Hanada, K. Natural ligand-nonmimetic inhibitors of the lipid-transfer protein CERT Commun Chem, 2019 Cited by DOI: 10.1038/s42004-019-0118-3 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation