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5CVW
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BU of 5cvw by Molmil
CRYSTAL STRUCTURE OF RTX DOMAIN BLOCK V OF ADENYLATE CYCLASE TOXIN FROM BORDETELLA PERTUSSIS
分子名称: 1,2-ETHANEDIOL, Bifunctional hemolysin/adenylate cyclase, CALCIUM ION, ...
著者Motlova, L, Barinka, C, Bumba, L.
登録日2015-07-27
公開日2015-09-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Calcium-Driven Folding of RTX Domain beta-Rolls Ratchets Translocation of RTX Proteins through Type I Secretion Ducts.
Mol.Cell, 62, 2016
6SZH
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BU of 6szh by Molmil
Acinetobacter baumannii undecaprenyl pyrophosphate synthase (AB-UppS) in complex with GW197
分子名称: 3,5-dimethyl-1~{H}-pyrrole-2-carbonitrile, CALCIUM ION, Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)
著者Thorpe, J.H.
登録日2019-10-02
公開日2020-01-22
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Cocktailed fragment screening by X-ray crystallography of the antibacterial target undecaprenyl pyrophosphate synthase from Acinetobacter baumannii.
Acta Crystallogr.,Sect.F, 76, 2020
8HLB
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BU of 8hlb by Molmil
Cryo-EM structure of biparatopic antibody Bp109-92 in complex with TNFR2
分子名称: TR109 heavy chain, TR109 light chain, TR92 heavy chain, ...
著者Akiba, H, Fujita, J, Ise, T, Nishiyama, K, Miyata, T, Kato, T, Namba, K, Ohno, H, Kamada, H, Nagata, S, Tsumoto, K.
登録日2022-11-29
公開日2023-10-04
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (3.63 Å)
主引用文献Development of a 1:1-binding biparatopic anti-TNFR2 antagonist by reducing signaling activity through epitope selection.
Commun Biol, 6, 2023
6NFA
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BU of 6nfa by Molmil
Vav1 inhibited by an allosteric inhibitor: Vav1 inhibitors block GEF activity
分子名称: (2S)-2-{[3-(4-methylphenyl)imidazo[1,2-a]pyrazin-8-yl]amino}-3-(pyridin-3-yl)propan-1-ol, Proto-oncogene vav, ZINC ION
著者Knapp, M.S, Elling, R.A, Ornelas, E.
登録日2018-12-19
公開日2019-12-25
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Allosteric Inhibitors of VAV1 Block Guanine Nucleotide Exchange Activity
To Be Published
4WVG
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BU of 4wvg by Molmil
Crystal structure of the Type-I signal peptidase from Staphylococcus aureus (SpsB).
分子名称: Maltose-binding periplasmic protein,Signal peptidase IB, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Young, P.G, Ting, Y.T, Baker, E.N.
登録日2014-11-05
公開日2015-09-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Peptide binding to a bacterial signal peptidase visualized by peptide tethering and carrier-driven crystallization.
IUCrJ, 3, 2016
5B3X
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BU of 5b3x by Molmil
Crystal structure of hPin1 WW domain (5-15) fused with maltose-binding protein in P41212 form
分子名称: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1,Maltose-binding periplasmic protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Hanazono, Y, Takeda, K, Miki, K.
登録日2016-03-17
公開日2016-10-26
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural studies of the N-terminal fragments of the WW domain: Insights into co-translational folding of a beta-sheet protein
Sci Rep, 6, 2016
4WJV
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BU of 4wjv by Molmil
Crystal structure of Rsa4 in complex with the Nsa2 binding peptide
分子名称: Maltose-binding periplasmic protein, Ribosome assembly protein 4, Ribosome biogenesis protein NSA2, ...
著者Holdermann, I, Paternoga, H, Bassler, J, Hurt, E, Sinning, I.
登録日2014-10-01
公開日2014-11-19
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献A network of assembly factors is involved in remodeling rRNA elements during preribosome maturation.
J.Cell Biol., 207, 2014
5BJZ
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BU of 5bjz by Molmil
Crystal structure of maltose binding protein in complex with an allosteric synthetic antibody
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, GLYCEROL, ...
著者Mukherjee, S, Kossiakoff, A.A.
登録日2017-09-12
公開日2018-01-17
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Engineered synthetic antibodies as probes to quantify the energetic contributions of ligand binding to conformational changes in proteins.
J. Biol. Chem., 293, 2018
5BMY
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BU of 5bmy by Molmil
Crystal structure of hPin1 WW domain (5-21) fused with maltose-binding protein
分子名称: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1,Maltose-binding periplasmic protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Hanazono, Y, Takeda, K, Miki, K.
登録日2015-05-25
公開日2016-10-26
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.001 Å)
主引用文献Structural studies of the N-terminal fragments of the WW domain: Insights into co-translational folding of a beta-sheet protein
Sci Rep, 6, 2016
6NDJ
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BU of 6ndj by Molmil
Crystal structure of human NLRP6 PYD domain with MBP fusion
分子名称: Maltose/maltodextrin-binding periplasmic protein, NACHT, LRR and PYD domains-containing protein 6 chimera
著者Shen, C, Fu, T.M, Wu, H.
登録日2018-12-13
公開日2019-01-23
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Molecular mechanism for NLRP6 inflammasome assembly and activation.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
5GXV
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BU of 5gxv by Molmil
Crystal structure of PigG
分子名称: MAGNESIUM ION, Maltose-binding periplasmic protein,PigG
著者Zhang, F, Ran, T, Xu, D, Wang, W.
登録日2016-09-20
公開日2017-07-19
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of MBP-PigG fusion protein and the essential function of PigG in the prodigiosin biosynthetic pathway in Serratia marcescens FS14.
Int. J. Biol. Macromol., 99, 2017
5DIS
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BU of 5dis by Molmil
Crystal structure of a CRM1-RanGTP-SPN1 export complex bound to a 113 amino acid FG-repeat containing fragment of Nup214
分子名称: Exportin-1, GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Monecke, T, Port, S.A, Dickmanns, A, Kehlenbach, R.H, Ficner, R.
登録日2015-09-01
公開日2015-11-04
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structural and Functional Characterization of CRM1-Nup214 Interactions Reveals Multiple FG-Binding Sites Involved in Nuclear Export.
Cell Rep, 13, 2015
5E24
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BU of 5e24 by Molmil
Structure of the Su(H)-Hairless-DNA Repressor Complex
分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*AP*AP*TP*CP*TP*TP*TP*CP*CP*CP*AP*CP*AP*GP*T)-3'), DNA (5'-D(*TP*TP*AP*CP*TP*GP*TP*GP*GP*GP*AP*AP*AP*GP*A)-3'), ...
著者Kovall, R.A, Yuan, Z.
登録日2015-09-30
公開日2016-06-15
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Structure and Function of the Su(H)-Hairless Repressor Complex, the Major Antagonist of Notch Signaling in Drosophila melanogaster.
Plos Biol., 14, 2016
5B3W
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BU of 5b3w by Molmil
Crystal structure of hPin1 WW domain (5-15) fused with maltose-binding protein in C2221 form
分子名称: CITRIC ACID, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1,Maltose-binding periplasmic protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Hanazono, Y, Takeda, K, Miki, K.
登録日2016-03-17
公開日2016-10-26
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural studies of the N-terminal fragments of the WW domain: Insights into co-translational folding of a beta-sheet protein
Sci Rep, 6, 2016
5H7N
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BU of 5h7n by Molmil
Crystal structure of human NLRP12-PYD with a MBP tag
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, NLRP12-PYD with MBP tag, ...
著者Jin, T.C, Xiao, T.S.
登録日2016-11-19
公開日2017-02-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.849 Å)
主引用文献Design of an expression system to enhance MBP-mediated crystallization
Sci Rep, 7, 2017
5AQ9
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BU of 5aq9 by Molmil
DARPin-based Crystallization Chaperones exploit Molecular Geometry as a Screening Dimension in Protein Crystallography
分子名称: MALTOSE-BINDING PERIPLASMIC PROTEIN, OFF7_DB08V4
著者Batyuk, A, Wu, Y, Honegger, A, Heberling, M, Plueckthun, A.
登録日2015-09-21
公開日2016-03-23
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Darpin-Based Crystallization Chaperones Exploit Molecular Geometry as a Screening Dimension in Protein Crystallography
J.Mol.Biol., 428, 2016
5BK1
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BU of 5bk1 by Molmil
Crystal structure of maltose binding protein in complex with an endosteric synthetic antibody
分子名称: CHLORIDE ION, GLYCEROL, Maltose binding protein, ...
著者Mukherjee, S, Kossiakoff, A.A.
登録日2017-09-12
公開日2018-01-17
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Engineered synthetic antibodies as probes to quantify the energetic contributions of ligand binding to conformational changes in proteins.
J. Biol. Chem., 293, 2018
5AZA
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BU of 5aza by Molmil
Crystal structure of MBP-sAglB fusion protein with a 20-residue spacer in the connector helix
分子名称: CALCIUM ION, Maltose-binding periplasmic protein,Oligosaccharyl transferase stt3 subunit related protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Matsuoka, R, Kohda, D.
登録日2015-09-27
公開日2016-01-13
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Rational design of crystal contact-free space in protein crystals for analyzing spatial distribution of motions within protein molecules.
Protein Sci., 25, 2016
5AMR
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BU of 5amr by Molmil
Structure of the La Crosse Bunyavirus polymerase in complex with the 3' viral RNA
分子名称: RNA, RNA POLYMERASE L
著者Reguera, J, Gerlach, P, Cusack, S.
登録日2015-03-12
公開日2015-06-03
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.57 Å)
主引用文献Structural Insights Into Bunyavirus Replication and its Regulation by the Vrna Promoter.
Cell(Cambridge,Mass.), 161, 2015
5HRB
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BU of 5hrb by Molmil
The crystal structure of AsfvPolX:DNA1 binary complex
分子名称: BETA-MERCAPTOETHANOL, DNA (5'-D(*CP*GP*GP*AP*TP*AP*TP*CP*C)-3'), DNA polymerase beta-like protein, ...
著者Chen, Y.Q, Zhang, J, Gan, J.H.
登録日2016-01-23
公開日2017-01-18
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The crystal structure of Se-AsfvPolX(L52/163M mutant) in complex with 1nt-gap DNA1
To Be Published
5HRH
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BU of 5hrh by Molmil
The crystal structure of AsfvPolX(H115F/R127A mutant): 1nt-gap(P) DNA2:dGTP ternary complex
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*GP*TP*TP*CP*TP*AP*TP*GP*TP*GP*TP*AP*CP*TP*CP*AP*C)-3'), DNA (5'-D(*GP*TP*GP*AP*GP*TP*AP*CP*A*)-3'), ...
著者Chen, Y.Q, Zhang, J, Gan, J.H.
登録日2016-01-23
公開日2017-01-18
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The crystal structure of Se-AsfvPolX(L52/163M mutant) in complex with 1nt-gap DNA1
To Be Published
5H7Q
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BU of 5h7q by Molmil
Crystal structure of human MNDA PYD domain with MBP tag
分子名称: ACETATE ION, MNDA PYD domain with MBP tag, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Jin, T.C, Xiao, T.S.
登録日2016-11-20
公開日2017-02-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.451 Å)
主引用文献Design of an expression system to enhance MBP-mediated crystallization
Sci Rep, 7, 2017
5CXL
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BU of 5cxl by Molmil
CRYSTAL STRUCTURE OF RTX DOMAIN BLOCK V OF ADENYLATE CYCLASE TOXIN FROM BORDETELLA PERTUSSIS
分子名称: Bifunctional hemolysin/adenylate cyclase, CALCIUM ION, NITRATE ION
著者Motlova, L, Barinka, C, Bumba, L.
登録日2015-07-29
公開日2015-09-02
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Calcium-Driven Folding of RTX Domain beta-Rolls Ratchets Translocation of RTX Proteins through Type I Secretion Ducts.
Mol.Cell, 62, 2016
5B3Z
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BU of 5b3z by Molmil
Crystal structure of hPin1 WW domain (5-39) fused with maltose-binding protein
分子名称: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1,Maltose-binding periplasmic protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Hanazono, Y, Takeda, K, Miki, K.
登録日2016-03-17
公開日2016-10-26
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural studies of the N-terminal fragments of the WW domain: Insights into co-translational folding of a beta-sheet protein
Sci Rep, 6, 2016
5DFM
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BU of 5dfm by Molmil
Structure of Tetrahymena telomerase p19 fused to MBP
分子名称: GLYCEROL, Maltose-binding periplasmic protein,Telomerase-associated protein 19, SULFATE ION, ...
著者Chan, H, Cascio, D, Sawaya, M.R, Feigon, J.
登録日2015-08-27
公開日2015-10-28
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.301 Å)
主引用文献Structure of Tetrahymena telomerase reveals previously unknown subunits, functions, and interactions.
Science, 350, 2015

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