PDB: 10243 件ウェブページステータス検索Chemie searchBIRD

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8UKU	RNA polymerase II elongation complex with Fapy-dG lesion with CMP added 分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... 著者 Hou, P, Oh, J, Wang, D. 登録日 2023-10-15 公開日 2024-04-24 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Molecular Mechanism of RNA Polymerase II Transcriptional Mutagenesis by the Epimerizable DNA Lesion, Fapy·dG. J.Am.Chem.Soc., 146, 2024
8UKR	RNA polymerase II elongation complex with Fapy-dG lesion soaking with ATP before chemistry 分子名称: ADENOSINE-5'-TRIPHOSPHATE, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ... 著者 Hou, P, Oh, J, Wang, D. 登録日 2023-10-15 公開日 2024-04-24 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (3.78 Å) 主引用文献 Molecular Mechanism of RNA Polymerase II Transcriptional Mutagenesis by the Epimerizable DNA Lesion, Fapy·dG. J.Am.Chem.Soc., 146, 2024
8UKS	RNA polymerase II elongation complex with Fapy-dG lesion soaking with CTP before chemistry 分子名称: CYTIDINE-5'-TRIPHOSPHATE, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ... 著者 Hou, P, Oh, J, Wang, D. 登録日 2023-10-15 公開日 2024-04-24 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Molecular Mechanism of RNA Polymerase II Transcriptional Mutagenesis by the Epimerizable DNA Lesion, Fapy·dG. J.Am.Chem.Soc., 146, 2024
8UKT	RNA polymerase II elongation complex with Fapy-dG lesion with AMP added 分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... 著者 Hou, P, Oh, J, Wang, D. 登録日 2023-10-15 公開日 2024-04-24 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Molecular Mechanism of RNA Polymerase II Transcriptional Mutagenesis by the Epimerizable DNA Lesion, Fapy·dG. J.Am.Chem.Soc., 146, 2024
5SVA	Mediator-RNA Polymerase II Pre-Initiation Complex 分子名称: 108bp HIS4 Promoter Non-template Strand (-92/+16), 108bp HIS4 Promoter Template Strand (+16/-92), DNA repair helicase RAD25, ... 著者 Robinson, P.J, Bushnell, D.A, Kornberg, R.D. 登録日 2016-08-05 公開日 2016-09-28 最終更新日 2024-11-20 実験手法 ELECTRON MICROSCOPY (15.3 Å) 主引用文献 Structure of a Complete Mediator-RNA Polymerase II Pre-Initiation Complex. Cell, 166, 2016
8UKQ	RNA polymerase II elongation complex with Fapy-dG lesion in apo state 分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... 著者 Hou, P, Oh, J, Wang, D. 登録日 2023-10-15 公開日 2024-04-24 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Molecular Mechanism of RNA Polymerase II Transcriptional Mutagenesis by the Epimerizable DNA Lesion, Fapy·dG. J.Am.Chem.Soc., 146, 2024
6UPZ	RNA polymerase II elongation complex with 5-guanidinohydantoin lesion in state 3 分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... 著者 Oh, J, Wang, D. 登録日 2019-10-18 公開日 2020-06-10 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 RNA polymerase II stalls on oxidative DNA damage via a torsion-latch mechanism involving lone pair-pi and CH-pi interactions. Proc.Natl.Acad.Sci.USA, 117, 2020
6UPY	RNA polymerase II elongation complex with 5-guanidinohydantoin lesion in state 2E 分子名称: DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ... 著者 Oh, J, Wang, D. 登録日 2019-10-18 公開日 2020-06-10 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 RNA polymerase II stalls on oxidative DNA damage via a torsion-latch mechanism involving lone pair-pi and CH-pi interactions. Proc.Natl.Acad.Sci.USA, 117, 2020
6UQ3	RNA polymerase II elongation complex with 5-guanidinohydantoin lesion in state 5 分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... 著者 Oh, J, Wang, D. 登録日 2019-10-18 公開日 2020-06-10 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (3.47 Å) 主引用文献 RNA polymerase II stalls on oxidative DNA damage via a torsion-latch mechanism involving lone pair-pi and CH-pi interactions. Proc.Natl.Acad.Sci.USA, 117, 2020
6UPX	RNA polymerase II elongation complex with 5-guanidinohydantoin lesion in state 1 分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... 著者 Oh, J, Wang, D. 登録日 2019-10-18 公開日 2020-06-10 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 RNA polymerase II stalls on oxidative DNA damage via a torsion-latch mechanism involving lone pair-pi and CH-pi interactions. Proc.Natl.Acad.Sci.USA, 117, 2020
6UQ0	RNA polymerase II elongation complex with 5-guanidinohydantoin lesion in state 4 分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... 著者 Oh, J, Wang, D. 登録日 2019-10-18 公開日 2020-06-10 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.56 Å) 主引用文献 RNA polymerase II stalls on oxidative DNA damage via a torsion-latch mechanism involving lone pair-pi and CH-pi interactions. Proc.Natl.Acad.Sci.USA, 117, 2020
6UQ2	RNA polymerase II elongation complex with dG in state 1 分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... 著者 Oh, J, Wang, D. 登録日 2019-10-18 公開日 2020-06-10 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 RNA polymerase II stalls on oxidative DNA damage via a torsion-latch mechanism involving lone pair-pi and CH-pi interactions. Proc.Natl.Acad.Sci.USA, 117, 2020
6UQ1	RNA polymerase II elongation complex with 5-guanidinohydantoin lesion in state 6 分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... 著者 Oh, J, Wang, D. 登録日 2019-10-18 公開日 2020-06-10 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 RNA polymerase II stalls on oxidative DNA damage via a torsion-latch mechanism involving lone pair-pi and CH-pi interactions. Proc.Natl.Acad.Sci.USA, 117, 2020
5XON	RNA Polymerase II elongation complex bound with Spt4/5 and TFIIS 分子名称: DNA (48-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... 著者 Ehara, H, Yokoyama, T, Shigematsu, H, Shirouzu, M, Sekine, S. 登録日 2017-05-29 公開日 2017-08-16 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.83 Å) 主引用文献 Structure of the complete elongation complex of RNA polymerase II with basal factors Science, 357, 2017
1I3Q	RNA POLYMERASE II CRYSTAL FORM I AT 3.1 A RESOLUTION 分子名称: DNA-DIRECTED RNA POLYMERASE II 13.6KD POLYPEPTIDE, DNA-DIRECTED RNA POLYMERASE II 14.2KD POLYPEPTIDE, DNA-DIRECTED RNA POLYMERASE II 14.5KD POLYPEPTIDE, ... 著者 Cramer, P, Bushnell, D.A, Kornberg, R.D. 登録日 2001-02-15 公開日 2001-04-25 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structural basis of transcription: RNA polymerase II at 2.8 angstrom resolution. Science, 292, 2001
1I6H	RNA POLYMERASE II ELONGATION COMPLEX 分子名称: 5'-D(P*AP*AP*AP*TP*GP*CP*CP*TP*GP*GP*TP*CP*T)-3', 5'-R(P*GP*AP*CP*CP*AP*GP*GP*CP*A)-3', DNA-DIRECTED RNA POLYMERASE II 13.6KD POLYPEPTIDE, ... 著者 Gnatt, A.L, Cramer, P, Kornberg, R.D. 登録日 2001-03-02 公開日 2001-04-23 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Structural basis of transcription: an RNA polymerase II elongation complex at 3.3 A resolution. Science, 292, 2001
4A93	RNA Polymerase II elongation complex containing a CPD Lesion 分子名称: 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP*CP*T*TTP*TP*TP*CP*C BRUP*GP*GP*TP*CP*AP*TP*T)-3', 5'-D(*TP*AP*AP*GP*TP*AP*CP*TP*TP*GP*AP*GP*CP*TP)-3', 5'-R(*UP*UP*CP*GP*AP*CP*CP*AP*GP*GP*AP*AP)-3', ... 著者 Walmacq, C, Cheung, A.C.M, Kireeva, M.L, Lubkowska, L, Ye, C, Gotte, D, Strathern, J.N, Carell, T, Cramer, P, Kashlev, M. 登録日 2011-11-23 公開日 2012-03-21 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Mechanism of Translesion Transcription by RNA Polymerase II and its Role in Cellular Resistance to DNA Damage. Mol.Cell, 46, 2012
1R9S	RNA POLYMERASE II STRAND SEPARATED ELONGATION COMPLEX, MATCHED NUCLEOTIDE 分子名称: DNA strand, DNA-directed RNA polymerase II 13.6 kDa polypeptide, DNA-directed RNA polymerase II 14.2 kDa polypeptide, ... 著者 Westover, K.D, Bushnell, D.A, Kornberg, R.D. 登録日 2003-10-30 公開日 2004-11-16 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (4.25 Å) 主引用文献 Structural basis of transcription: nucleotide selection by rotation in the RNA polymerase II active center. Cell(Cambridge,Mass.), 119, 2004
1R9T	RNA POLYMERASE II STRAND SEPARATED ELONGATION COMPLEX, MISMATCHED NUCLEOTIDE 分子名称: ADENOSINE-5'-TRIPHOSPHATE, DNA nontemplate strand, DNA template strand, ... 著者 Westover, K.D, Bushnell, D.A, Kornberg, R.D. 登録日 2003-10-30 公開日 2004-11-16 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Structural basis of transcription: nucleotide selection by rotation in the RNA polymerase II active center. Cell(Cambridge,Mass.), 119, 2004
1SFO	RNA POLYMERASE II STRAND SEPARATED ELONGATION COMPLEX 分子名称: DNA STRAND, DNA-directed RNA polymerase II 13.6 kDa polypeptide, DNA-directed RNA polymerase II 14.2 kDa polypeptide, ... 著者 Westover, K.D, Bushnell, D.A, Kornberg, R.D. 登録日 2004-02-20 公開日 2004-03-02 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (3.61 Å) 主引用文献 Structural Basis of Transcription: Separation of RNA from DNA by RNA Polymerase II Science, 303, 2004
1R5U	RNA POLYMERASE II TFIIB COMPLEX 分子名称: DNA-directed RNA polymerase II 13.6 kDa polypeptide, DNA-directed RNA polymerase II 14.2 kDa polypeptide, DNA-directed RNA polymerase II 140 kDa polypeptide, ... 著者 Bushnell, D.A, Westover, K.D, Davis, R, Kornberg, R.D. 登録日 2003-10-13 公開日 2004-02-17 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (4.5 Å) 主引用文献 Structural basis of transcription: an RNA polymerase II-TFIIB cocrystal at 4.5 Angstroms. Science, 303, 2004
3H0G	RNA Polymerase II from Schizosaccharomyces pombe 分子名称: DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, ... 著者 Spahr, H, Calero, G, Bushnell, D.A, Kornberg, R.D. 登録日 2009-04-09 公開日 2009-08-25 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (3.65 Å) 主引用文献 Schizosacharomyces pombe RNA polymerase II at 3.6-A resolution. Proc.Natl.Acad.Sci.USA, 106, 2009
3CQZ	Crystal structure of 10 subunit RNA polymerase II in complex with the inhibitor alpha-amanitin 分子名称: ALPHA-AMANITIN, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, ... 著者 Kaplan, C.D, Larsson, K.-M, Kornberg, R.D. 登録日 2008-04-03 公開日 2008-07-22 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 The RNA Polymerase II Trigger Loop Functions in Substrate Selection and is Directly Targeted by Alpha-Amanitin. Mol.Cell, 30, 2008
7NVR	Human Mediator with RNA Polymerase II Pre-initiation complex 分子名称: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... 著者 Rengachari, S, Schilbach, S, Aibara, S, Cramer, P. 登録日 2021-03-15 公開日 2021-05-05 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Structures of mammalian RNA polymerase II pre-initiation complexes. Nature, 594, 2021
8CEO	Yeast RNA polymerase II transcription pre-initiation complex with core Mediator and the +1 nucleosome 分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... 著者 Wang, H, Cramer, P. 登録日 2023-02-02 公開日 2023-03-08 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Yeast PIC-Mediator structure with RNA polymerase II C-terminal domain. Proc.Natl.Acad.Sci.USA, 120, 2023

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