PDB: 284 件ウェブページステータス検索Chemie searchBIRD

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4O3P	Crystal structure of human polymerase eta inserting dctp opposite an 8-oxog containing dna template 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*(8OG)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), ... 著者 Patra, A, Egli, M. 登録日 2013-12-18 公開日 2014-04-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 Kinetics, Structure, and Mechanism of 8-Oxo-7,8-dihydro-2'-deoxyguanosine Bypass by Human DNA Polymerase eta J.Biol.Chem., 289, 2014
4O3Q	Crystal structure of human polymerase eta inserting dgtp opposite an 8-oxog containing dna template 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*(8OG)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), ... 著者 Patra, A, Egli, M. 登録日 2013-12-18 公開日 2014-04-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 Kinetics, Structure, and Mechanism of 8-Oxo-7,8-dihydro-2'-deoxyguanosine Bypass by Human DNA Polymerase eta J.Biol.Chem., 289, 2014
4RNN	Crystal structure of human polymerase eta inserting dGMPnPP opposite DNA template containing an abasic site 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA polymerase eta, GLYCEROL, ... 著者 Patra, A, Egli, M. 登録日 2014-10-24 公開日 2015-02-18 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.808 Å) 主引用文献 Structural and Kinetic Analysis of Nucleoside Triphosphate Incorporation Opposite an Abasic Site by Human Translesion DNA Polymerase eta. J.Biol.Chem., 290, 2015
4RU9	Crystal structure of human DNA polymerase eta inserting dCMPNPP opposite a MeFapy-dG adducted DNA template 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA polymerase eta, MAGNESIUM ION, ... 著者 Patra, A, Egli, M. 登録日 2014-11-18 公開日 2015-08-05 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Structural Basis for Error-Free Bypass of the 5-N-Methylformamidopyrimidine-dG Lesion by Human DNA Polymerase eta and Sulfolobus solfataricus P2 Polymerase IV. J.Am.Chem.Soc., 137, 2015
5DG8	CRYSTAL STRUCTURE OF HUMAN DNA POLYMERASE ETA INSERTING dAMPNPP ACROSS A DNA TEMPLATE CONTAINING 1,N6-ETHENODEOXYADENOSINE LESION 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*(EDA)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), ... 著者 Patra, A, Egli, M. 登録日 2015-08-27 公開日 2016-06-08 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.12 Å) 主引用文献 Structural and Kinetic Analysis of Miscoding Opposite the DNA Adduct 1,N6-Ethenodeoxyadenosine by Human Translesion DNA Polymerase eta. J.Biol.Chem., 291, 2016
5DG7	CRYSTAL STRUCTURE OF HUMAN DNA POLYMERASE ETA INSERTING dTTP ACROSS A DNA TEMPLATE CONTAINING 1,N6-ETHENODEOXYADENOSINE LESION 分子名称: CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*(EDA)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), ... 著者 Patra, A, Egli, M. 登録日 2015-08-27 公開日 2016-06-08 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.26 Å) 主引用文献 Structural and Kinetic Analysis of Miscoding Opposite the DNA Adduct 1,N6-Ethenodeoxyadenosine by Human Translesion DNA Polymerase eta. J.Biol.Chem., 291, 2016
5DGB	CRYSTAL STRUCTURE OF HUMAN DNA POLYMERASE ETA EXTENDING AN 1,N6-ETHENODEOXYADENOSINE : dA PAIR BY INSERTING dTMPNPP OPPOSITE TEMPLATE dA 分子名称: 5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]thymidine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*A)-3'), DNA (5'-D(*CP*AP*TP*AP*(EDA)P*TP*GP*AP*CP*GP*CP*T)-3'), ... 著者 Patra, A, Egli, M. 登録日 2015-08-27 公開日 2016-06-08 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Structural and Kinetic Analysis of Miscoding Opposite the DNA Adduct 1,N6-Ethenodeoxyadenosine by Human Translesion DNA Polymerase eta. J.Biol.Chem., 291, 2016
5DQH	Crystal Structure of Human DNA Polymerase Eta Inserting dGMPNPP Opposite O4-Ethylthymidine 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*(5EJ)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), ... 著者 Patra, A, OFlaherty, D.K, Egli, M. 登録日 2015-09-14 公開日 2016-08-10 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Lesion Orientation ofO4-Alkylthymidine Influences Replication by Human DNA Polymeraseeta. Chem Sci, 7, 2016
5DLF	Crystal Structure of Human DNA Polymerase Eta Inserting dATP Opposite O4-Methylhymidine 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... 著者 Patra, A, OFlaherty, D.K, Egli, M. 登録日 2015-09-04 公開日 2016-08-10 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Lesion Orientation ofO4-Alkylthymidine Influences Replication by Human DNA Polymeraseeta. Chem Sci, 7, 2016
5DGA	CRYSTAL STRUCTURE OF HUMAN DNA POLYMERASE ETA EXTENDING AN 1,N6-ETHENODEOXYADENOSINE : dT PAIR BY INSERTING dTMPNPP OPPOSITE TEMPLATE dA 分子名称: 5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]thymidine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*AP*(EDA)P*TP*GP*AP*CP*GP*CP*T)-3'), ... 著者 Patra, A, Egli, M. 登録日 2015-08-27 公開日 2016-06-08 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural and Kinetic Analysis of Miscoding Opposite the DNA Adduct 1,N6-Ethenodeoxyadenosine by Human Translesion DNA Polymerase eta. J.Biol.Chem., 291, 2016
5DQG	Crystal Structure of Human DNA Polymerase Eta Inserting dAMPNPP Opposite O4-Ethylthymidine 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*(5EJ)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), ... 著者 Patra, A, OFlaherty, D.K, Egli, M. 登録日 2015-09-14 公開日 2016-08-10 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.29 Å) 主引用文献 Lesion Orientation ofO4-Alkylthymidine Influences Replication by Human DNA Polymeraseeta. Chem Sci, 7, 2016
5DLG	Crystal Structure of Human DNA Polymerase Eta Inserting dGMPNPP Opposite O4-Methylhymidine 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*(5DB)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), ... 著者 Patra, A, OFlaherty, D.K, Egli, M. 登録日 2015-09-04 公開日 2016-08-10 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.351 Å) 主引用文献 Lesion Orientation ofO4-Alkylthymidine Influences Replication by Human DNA Polymeraseeta. Chem Sci, 7, 2016
5DG9	CRYSTAL STRUCTURE OF HUMAN DNA POLYMERASE ETA INSERTING dGMPNPP ACROSS A DNA TEMPLATE CONTAINING 1,N6-ETHENODEOXYADENOSINE LESION 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*(EDA)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), ... 著者 Patra, A, Egli, M. 登録日 2015-08-27 公開日 2016-06-08 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Structural and Kinetic Analysis of Miscoding Opposite the DNA Adduct 1,N6-Ethenodeoxyadenosine by Human Translesion DNA Polymerase eta. J.Biol.Chem., 291, 2016
5DQI	Crystal Structure of Human DNA Polymerase Eta Extending an O4-Ethylthymidine : dA Pair By Inserting dCTP Opposite dG 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*AP*C)-3'), ... 著者 Patra, A, OFlaherty, D.K, Egli, M. 登録日 2015-09-14 公開日 2016-08-10 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Lesion Orientation ofO4-Alkylthymidine Influences Replication by Human DNA Polymeraseeta. Chem Sci, 7, 2016
5EWG	Ternary complex of human DNA polymerase eta inserting rATP opposite an 8-Oxodeoxyguanosine Lesion 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... 著者 Su, Y, Egli, M, Guengerich, F.P. 登録日 2015-11-20 公開日 2016-01-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Mechanism of Ribonucleotide Incorporation by Human DNA Polymerase eta. J.Biol.Chem., 291, 2016
5EWF	Ternary complex of human DNA polymerase eta inserting rCTP opposite an 8-Oxodeoxyguanosine Lesion 分子名称: CALCIUM ION, CYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... 著者 Su, Y, Egli, M, Guengerich, F.P. 登録日 2015-11-20 公開日 2016-01-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.782 Å) 主引用文献 Mechanism of Ribonucleotide Incorporation by Human DNA Polymerase eta. J.Biol.Chem., 291, 2016
5EWE	Ternary complex of human DNA polymerase eta inserting rCTP opposite template G 分子名称: CALCIUM ION, CYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... 著者 Su, Y, Egli, M, Guengerich, F.P. 登録日 2015-11-20 公開日 2016-01-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.66 Å) 主引用文献 Mechanism of Ribonucleotide Incorporation by Human DNA Polymerase eta. J.Biol.Chem., 291, 2016
8V7B	Human DNA polymerase eta-DNA-dT primer araCTP insertion ternary complex at pH7.0 (K+ MES) with 1 Ca2+ ion 分子名称: 4-amino-1-{5-O-[(S)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-beta-D-arabinofuranosyl}pyrimidin-2(1H)-one, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T*())-3'), ... 著者 Chang, C, Gao, Y. 登録日 2023-12-04 公開日 2024-05-15 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Human DNA polymerase eta-DNA-dT primer araCTP insertion ternary complex at pH7.0 (K+ MES) with 1 Ca2+ ion To Be Published
8V7G	Human DNA polymerase eta-DNA-gemC-ended primer-dAMPNPP ternary complex with Mg2+ 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*(U7B))-3'), DNA (5'-D(*CP*AP*TP*TP*GP*TP*GP*AP*CP*GP*CP*T)-3'), ... 著者 Chang, C, Gao, Y. 登録日 2023-12-04 公開日 2024-05-15 実験手法 X-RAY DIFFRACTION (1.52 Å) 主引用文献 Human DNA polymerase eta-DNA-araC-ended primer-dAMPNPP ternary complex with Mn2+ To Be Published
8V7I	Human DNA polymerase eta-DNA-araC-ended primer ternary complex:reaction with 1 mM Mg2+ for 1800s 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*A)-R(P*(CAR))-3'), DNA (5'-D(*CP*AP*TP*TP*GP*TP*GP*AP*CP*GP*CP*T)-3'), ... 著者 Chang, C, Gao, Y. 登録日 2023-12-04 公開日 2024-05-15 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 Human DNA polymerase eta-DNA-araC-ended primer ternary complex:reaction with 1 mM Mg2+ for 1800s To Be Published
8V7K	Human DNA polymerase eta-DNA-araC-ended primer ternary complex:reaction with 10 mM Mn2+ for 1800s 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*A)-R(P*(CAR))-3'), DNA (5'-D(*CP*AP*TP*TP*GP*TP*GP*AP*CP*GP*CP*T)-3'), ... 著者 Chang, C, Gao, Y. 登録日 2023-12-04 公開日 2024-05-15 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Human DNA polymerase eta-DNA-araC-ended primer ternary complex:reaction with 10 mM Mn2+ for 1800s To Be Published
8V7A	Human DNA polymerase eta-DNA-dT primer dCTP insertion ternary complex at pH7.0 (K+ MES) with 1 Ca2+ ion 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T*())-3'), ... 著者 Chang, C, Gao, Y. 登録日 2023-12-04 公開日 2024-05-15 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Human DNA polymerase eta-DNA-dT primer dCTP insertion ternary complex at pH7.0 (K+ MES) with 1 Ca2+ ion To Be Published
8V7C	Human DNA polymerase eta-DNA-dT primer gemCTP insertion ternary complex at pH7.0 (K+ MES) with 1 Ca2+ ion 分子名称: 2'-deoxy-2',2'-difluorocytidine 5'-(tetrahydrogen triphosphate), CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T*())-3'), ... 著者 Chang, C, Gao, Y. 登録日 2023-12-04 公開日 2024-05-15 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Human DNA polymerase eta-DNA-dT primer gemCTP insertion ternary complex at pH7.0 (K+ MES) with 1 Ca2+ ion To Be Published
8V7F	Human DNA polymerase eta-DNA-araC-ended primer-dAMPNPP ternary complex with Mn2+ 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T*())-3'), DNA (5'-D(*CP*AP*TP*GP*AP*TP*GP*AP*CP*GP*CP*T)-3'), ... 著者 Chang, C, Gao, Y. 登録日 2023-12-04 公開日 2024-05-15 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Human DNA polymerase eta-DNA-araC-ended primer-dAMPNPP ternary complex with Mn2+ To Be Published
8V7J	Human DNA polymerase eta-DNA-araC-ended primer ternary complex:reaction with 20 mM Mg2+ for 600s 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*A)-R(P*(CAR))-3'), DNA (5'-D(*CP*AP*TP*TP*GP*TP*GP*AP*CP*GP*CP*T)-3'), ... 著者 Chang, C, Gao, Y. 登録日 2023-12-04 公開日 2024-05-15 実験手法 X-RAY DIFFRACTION (1.66 Å) 主引用文献 Human DNA polymerase eta-DNA-araC-ended primer ternary complex:reaction with 20 mM Mg2+ for 600s To Be Published

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