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7Q3X
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Crystal structure of Malate dehydrogenase from Haloarcula marismortui with Potassium and Chloride ions
分子名称: CHLORIDE ION, Malate dehydrogenase, POTASSIUM ION
著者Bertrand, Q, Roche, J, Girard, E, Madern, D.
登録日2021-10-29
公開日2022-02-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Resurrection of Ancestral Malate Dehydrogenases Reveals the Evolutionary History of Haloarchaeal Proteins.
To Be Published
6MV8
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BU of 6mv8 by Molmil
LDHA structure in complex with inhibitor 14
分子名称: (6S)-3-[(2-chlorophenyl)sulfanyl]-4-hydroxy-6-(2-hydroxyphenyl)-6-phenyl-5,6-dihydro-2H-pyran-2-one, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
著者Eigenbrot, C.E, Ultsch, M, Wei, B.
登録日2018-10-24
公開日2019-10-30
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structure-based Optimization of Potent, Cell-Active Hydroxylactam Inhibitors of Lactate Dehydrogenase
To Be Published
3LDH
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BU of 3ldh by Molmil
A comparison of the structures of apo dogfish m4 lactate dehydrogenase and its ternary complexes
分子名称: LACTATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PYRUVIC ACID
著者White, J.L, Hackert, M.L, Buehner, M, Adams, M.J, Ford, G.C, Lentzjunior, P.J, Smiley, I.E, Steindel, S.J, Rossmann, M.G.
登録日1974-06-06
公開日1977-04-29
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A comparison of the structures of apo dogfish M4 lactate dehydrogenase and its ternary complexes.
J.Mol.Biol., 102, 1976
6CEP
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BU of 6cep by Molmil
Sus scrofa heart L-lactate dehydrogenase ternary complex with NADH and oxamate
分子名称: L-lactate dehydrogenase B chain, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, OXAMIC ACID
著者Hoffer, E.D, Andrews, B, Dunham, C.M, Dyer, R.B.
登録日2018-02-12
公開日2018-06-27
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Small molecule cores demonstrate non-competitive inhibition of lactate dehydrogenase.
Medchemcomm, 9, 2018
8J5D
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BU of 8j5d by Molmil
Cryo-EM structure of starch degradation complex of BAM1-LSF1-MDH
分子名称: Beta-amylase 1, chloroplastic, Malate dehydrogenase, ...
著者Guan, Z.Y, Liu, J, Yan, J.J.
登録日2023-04-21
公開日2024-01-10
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献The LIKE SEX FOUR 1-malate dehydrogenase complex functions as a scaffold to recruit beta-amylase to promote starch degradation.
Plant Cell, 36, 2023
9FQR
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BU of 9fqr by Molmil
96-nm repeat of axonemal doublet microtubules from bovine sperm
分子名称: A-kinase anchoring protein 14, ATP6V1F neighbor, Actin, ...
著者Leung, M.R, Sun, C, Zeng, J, Anderson, J.R, Niu, Q, Huang, W, Noteborn, W.E.M, Brown, A, Zeev-Ben-Mordehai, T, Zhang, R.
登録日2024-06-21
公開日2025-03-26
実験手法ELECTRON MICROSCOPY (5 Å)
主引用文献Structural diversity of axonemes across mammalian motile cilia.
Nature, 637, 2025
6ZZR
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BU of 6zzr by Molmil
The Crystal Structure of human LDHA from Biortus.
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, L-lactate dehydrogenase A chain
著者Wang, F, Lin, D, Cheng, W, Bao, X, Zhu, B, Shang, H.
登録日2020-08-05
公開日2020-08-19
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献The Crystal Structure of human LDHA from Biortus
To Be Published
6MVA
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BU of 6mva by Molmil
LDHA structure in complex with inhibitor 14
分子名称: (6R)-6-(3-aminophenyl)-3-[(2-chlorophenyl)sulfanyl]-4-hydroxy-6-(thiophen-3-yl)-5,6-dihydro-2H-pyran-2-one, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
著者Eigenbrot, C.E, Ultsch, M, Wei, B.
登録日2018-10-24
公開日2019-10-30
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Structure-based Optimization of Potent, Cell-Active Hydroxylactam Inhibitors of Lactate Dehydrogenase
To Be Published
4ZVV
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Lactate dehydrogenase A in complex with a trisubstituted piperidine-2,4-dione inhibitor GNE-140
分子名称: (2~{R})-5-(2-chlorophenyl)sulfanyl-2-(4-morpholin-4-ylphenyl)-4-oxidanyl-2-thiophen-3-yl-1,3-dihydropyridin-6-one, L-lactate dehydrogenase A chain, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
著者Li, Y, Chen, Z, Eigenbrot, C.
登録日2015-05-18
公開日2016-05-18
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Metabolic plasticity underpins innate and acquired resistance to LDHA inhibition.
Nat.Chem.Biol., 12, 2016
8XKV
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Cryo-EM structure of the Ycf2-FtsHi motor complex from Arabidopsis in Apo state
分子名称: 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, ATP-dependent zinc metalloprotease FTSH 12, chloroplastic, ...
著者Liang, K, Zhan, X, Xu, Q, Wu, J, Yan, Z.
登録日2023-12-25
公開日2024-09-11
最終更新日2025-06-25
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural insights into the chloroplast protein import in land plants.
Cell, 187, 2024
8XKU
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Cryo-EM structure of the Ycf2-FtsHi motor complex from Arabidopsis in ATP-bound state
分子名称: 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent zinc metalloprotease FTSH 12, ...
著者Liang, K, Zhan, X, Xu, Q, Wu, J, Yan, Z.
登録日2023-12-24
公開日2024-09-11
最終更新日2025-06-25
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural insights into the chloroplast protein import in land plants.
Cell, 187, 2024
8LDH
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BU of 8ldh by Molmil
REFINED CRYSTAL STRUCTURE OF DOGFISH M4 APO-LACTATE DEHYDROGENASE
分子名称: CITRIC ACID, M4 APO-LACTATE DEHYDROGENASE
著者Abad-Zapatero, C, Rossmann, M.G.
登録日1988-01-04
公開日1989-07-12
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Refined crystal structure of dogfish M4 apo-lactate dehydrogenase.
J.Mol.Biol., 198, 1987
8QDE
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Crystal structure of a truncated human L-Lactate Dehydrogenase B protein in complex with NADH and oxamate
分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, DI(HYDROXYETHYL)ETHER, L-lactate dehydrogenase B chain, ...
著者Van Gysel, M, Wouters, J.
登録日2023-08-29
公開日2024-09-11
実験手法X-RAY DIFFRACTION (2.98 Å)
主引用文献Crystal structure of a truncated human L-Lactate Dehydrogenase B protein in complex with NADH and oxamate
To Be Published
8Q3C
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BU of 8q3c by Molmil
Structure of Selenomonas ruminantium lactate dehydrogenase I85R mutant
分子名称: CHLORIDE ION, L-lactate dehydrogenase, NITRATE ION, ...
著者Bertrand, Q, Coquille, S, Iorio, A, Sterpone, F, Madern, D.
登録日2023-08-03
公開日2023-11-01
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Biochemical, structural and dynamical characterizations of the lactate dehydrogenase from Selenomonas ruminantium provide information about an intermediate evolutionary step prior to complete allosteric regulation acquisition in the super family of lactate and malate dehydrogenases.
J.Struct.Biol., 215, 2023
2ZQY
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BU of 2zqy by Molmil
T-state structure of allosteric L-lactate dehydrogenase from Lactobacillus casei
分子名称: L-lactate dehydrogenase, NITRATE ION
著者Arai, K, Ishimitsu, T, Fushinobu, S, Uchikoba, H, Matsuzawa, H, Taguchi, H.
登録日2008-08-22
公開日2009-09-08
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Active and inactive state structures of unliganded Lactobacillus casei allosteric L-lactate dehydrogenase.
Proteins, 78, 2010
3NEP
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BU of 3nep by Molmil
1.55A resolution structure of malate dehydrogenase from Salinibacter ruber
分子名称: Malate dehydrogenase
著者Coquelle, N, Madern, D.
登録日2010-06-09
公開日2010-10-13
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.551 Å)
主引用文献Gradual adaptive changes of a protein facing high salt concentrations.
J.Mol.Biol., 404, 2010
2V6B
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BU of 2v6b by Molmil
Crystal structure of lactate dehydrogenase from Deinococcus Radiodurans (apo form)
分子名称: L-LACTATE DEHYDROGENASE
著者Coquelle, N, Fioravanti, E, Weik, M, Vellieux, F.
登録日2007-07-16
公開日2007-09-25
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Activity, stability and structural studies of lactate dehydrogenases adapted to extreme thermal environments.
J. Mol. Biol., 374, 2007
1PZE
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T.gondii LDH1 apo form
分子名称: lactate dehydrogenase
著者Kavanagh, K.L, Elling, R.A, Wilson, D.K.
登録日2003-07-10
公開日2004-02-24
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structure of Toxoplasma gondii LDH1: Active-Site Differences from Human Lactate Dehydrogenases and the Structural Basis for Efficient APAD+ Use.
Biochemistry, 43, 2004
1PZF
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T.gondii LDH1 ternary complex with APAD+ and oxalate
分子名称: 3-ACETYLPYRIDINE ADENINE DINUCLEOTIDE, OXALATE ION, lactate dehydrogenase
著者Kavanagh, K.L, Elling, R.A, Wilson, D.K.
登録日2003-07-10
公開日2004-02-24
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of Toxoplasma gondii LDH1: Active-Site Differences from Human Lactate Dehydrogenases and the Structural Basis for Efficient APAD+ Use.
Biochemistry, 43, 2004
1PZH
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T.gondii LDH1 ternary complex with NAD and oxalate
分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, OXALATE ION, lactate dehydrogenase
著者Kavanagh, K.L, Elling, R.A, Wilson, D.K.
登録日2003-07-10
公開日2004-02-24
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of Toxoplasma gondii LDH1: Active-Site Differences from Human Lactate Dehydrogenases and the Structural Basis for Efficient APAD+ Use.
Biochemistry, 43, 2004
1PZG
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BU of 1pzg by Molmil
T.gondii LDH1 complexed with APAD and sulfate at 1.6 Angstroms
分子名称: 3-ACETYLPYRIDINE ADENINE DINUCLEOTIDE, SULFATE ION, lactate dehydrogenase
著者Kavanagh, K.L, Elling, R.A, Wilson, D.K.
登録日2003-07-10
公開日2004-02-24
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure of Toxoplasma gondii LDH1: Active-Site Differences from Human Lactate Dehydrogenases and the Structural Basis for Efficient APAD+ Use.
Biochemistry, 43, 2004
3TL2
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BU of 3tl2 by Molmil
Crystal structure of Bacillus anthracis str. Ames malate dehydrogenase in closed conformation.
分子名称: 1,2-ETHANEDIOL, Malate dehydrogenase, THIOCYANATE ION
著者Blus, B.J, Chruszcz, M, Tkaczuk, K.L, Osinski, T, Cymborowski, M, Kudritska, M, Grimshaw, S, Savchenko, A, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2011-08-29
公開日2011-09-21
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of Bacillus anthracis str. Ames malate dehydrogenase in closed conformation.
TO BE PUBLISHED
2V65
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Apo LDH from the psychrophile C. gunnari
分子名称: L-LACTATE DEHYDROGENASE A CHAIN
著者Coquelle, N, Madern, D, Vellieux, F.
登録日2007-07-13
公開日2007-09-25
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Activity, Stability and Structural Studies of Lactate Dehydrogenases Adapted to Extreme Thermal Environments.
J.Mol.Biol., 374, 2007
2V6M
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Crystal structure of lactate dehydrogenase from Thermus Thermophilus HB8 (Apo form)
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, L-LACTATE DEHYDROGENASE
著者Coquelle, N, Fioravanti, E, Weik, M, Vellieux, F.
登録日2007-07-19
公開日2007-09-25
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Activity, stability and structural studies of lactate dehydrogenases adapted to extreme thermal environments.
J. Mol. Biol., 374, 2007
2V7P
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Crystal structure of lactate dehydrogenase from Thermus Thermophilus HB8 (Holo form)
分子名称: L-LACTATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, OXAMIC ACID
著者Coquelle, N, Fioravanti, E, Weik, M, Vellieux, F.
登録日2007-07-31
公開日2007-09-25
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Activity, stability and structural studies of lactate dehydrogenases adapted to extreme thermal environments.
J. Mol. Biol., 374, 2007

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