6CEP
Sus scrofa heart L-lactate dehydrogenase ternary complex with NADH and oxamate
Summary for 6CEP
| Entry DOI | 10.2210/pdb6cep/pdb |
| Descriptor | L-lactate dehydrogenase B chain, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, OXAMIC ACID, ... (4 entities in total) |
| Functional Keywords | ternary complex, heart isoform (h-chain), oxidoreductase |
| Biological source | Sus scrofa (Pig) |
| Total number of polymer chains | 4 |
| Total formula weight | 149614.95 |
| Authors | Hoffer, E.D.,Andrews, B.,Dunham, C.M.,Dyer, R.B. (deposition date: 2018-02-12, release date: 2018-06-27, Last modification date: 2023-10-04) |
| Primary citation | Andrews, B.A.,Dyer, R.B. Small molecule cores demonstrate non-competitive inhibition of lactate dehydrogenase. Medchemcomm, 9:1369-1376, 2018 Cited by PubMed: 30151092DOI: 10.1039/c8md00309b PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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