PDB: 203 件ウェブページステータス検索Chemie searchBIRD

---

5TUK	Crystal structure of tetracycline destructase Tet(51) 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, Tetracycline destructase Tet(51) 著者 Park, J, Tolia, N.H. 登録日 2016-11-06 公開日 2017-05-10 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Plasticity, dynamics, and inhibition of emerging tetracycline resistance enzymes. Nat. Chem. Biol., 13, 2017
4A99	STRUCTURE OF THE TETRACYCLINE DEGRADING MONOOXYGENASE TETX IN COMPLEX WITH MINOCYCLINE 分子名称: (4S,4AS,5AR,12AS)-4,7-BIS(DIMETHYLAMINO)-3,10,12,12A-TETRAHYDROXY-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2- CARBOXAMIDE, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, ... 著者 Volkers, G, Palm, G.J, Weiss, M.S, Hinrichs, W. 登録日 2011-11-25 公開日 2012-12-12 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.18 Å) 主引用文献 Putative Dioxygen-Binding Sites and Recognition of Tigecycline and Minocycline in the Tetracycline-Degrading Monooxygenase Tetx Acta Crystallogr.,Sect.D, 69, 2013
5TUI	Crystal structure of tetracycline destructase Tet(50) in complex with chlortetracycline 分子名称: 7-CHLOROTETRACYCLINE, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, ... 著者 Park, J, Tolia, N.H. 登録日 2016-11-06 公開日 2017-05-10 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Plasticity, dynamics, and inhibition of emerging tetracycline resistance enzymes. Nat. Chem. Biol., 13, 2017
4BJZ	Crystal structure of 3-hydroxybenzoate 6-hydroxylase uncovers lipid- assisted flavoprotein strategy for regioselective aromatic hydroxylation: Native data 分子名称: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, PHOSPHATIDYLGLYCEROL-PHOSPHOGLYCEROL, ... 著者 Orru, R, Montersino, S, Barendregt, A, Westphal, A.H, van Duijn, E, Mattevi, A, van Berkel, W.J.H. 登録日 2013-04-21 公開日 2013-07-24 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.51 Å) 主引用文献 Crystal Structure of 3-Hydroxybenzoate 6-Hydroxylase Uncovers Lipid-Assisted Flavoprotein Strategy for Regioselective Aromatic Hydroxylation J.Biol.Chem., 288, 2013
4BJY	Crystal structure of 3-hydroxybenzoate 6-hydroxylase uncovers lipid- assisted flavoprotein strategy for regioselective aromatic hydroxylation: Platinum derivative 分子名称: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, PHOSPHATIDYLGLYCEROL-PHOSPHOGLYCEROL, ... 著者 Orru, R, Montersino, S, Barendregt, A, Westphal, A.H, van Duijn, E, Mattevi, A, van Berkel, W.J.H. 登録日 2013-04-21 公開日 2013-07-24 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.52 Å) 主引用文献 Crystal Structure of 3-Hydroxybenzoate 6-Hydroxylase Uncovers Lipid-Assisted Flavoprotein Strategy for Regioselective Aromatic Hydroxylation J.Biol.Chem., 288, 2013
5TUE	Crystal structure of tetracycline destructase Tet(50) 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, Tetracycline destructase Tet(50) 著者 Park, J, Tolia, N.H. 登録日 2016-11-05 公開日 2017-05-10 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Plasticity, dynamics, and inhibition of emerging tetracycline resistance enzymes. Nat. Chem. Biol., 13, 2017
4A6N	STRUCTURE OF THE TETRACYCLINE DEGRADING MONOOXYGENASE TETX IN COMPLEX WITH TIGECYCLINE 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, TETX2 PROTEIN, ... 著者 Volkers, G, Palm, G.J, Weiss, M.S, Hinrichs, W. 登録日 2011-11-07 公開日 2012-11-21 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Putative Dioxygen-Binding Sites and Recognition of Tigecycline and Minocycline in the Tetracycline-Degrading Monooxygenase Tetx Acta Crystallogr.,Sect.D, 69, 2013
4BK1	Crystal structure of 3-hydroxybenzoate 6-hydroxylase uncovers lipid- assisted flavoprotein strategy for regioselective aromatic hydroxylation: H213S mutant in complex with 3-hydroxybenzoate 分子名称: 3-HYDROXYBENZOIC ACID, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Orru, R, Montersino, S, Barendregt, A, Westphal, A.H, van Duijn, E, Mattevi, A, van Berkel, W.J.H. 登録日 2013-04-21 公開日 2013-07-24 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Crystal Structure of 3-Hydroxybenzoate 6-Hydroxylase Uncovers Lipid-Assisted Flavoprotein Strategy for Regioselective Aromatic Hydroxylation J.Biol.Chem., 288, 2013
4BK2	Crystal structure of 3-hydroxybenzoate 6-hydroxylase uncovers lipid- assisted flavoprotein strategy for regioselective aromatic hydroxylation: Q301E mutant 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, PHOSPHATIDYLGLYCEROL-PHOSPHOGLYCEROL, PROBABLE SALICYLATE MONOOXYGENASE 著者 Orru, R, Montersino, S, Barendregt, A, Westphal, A.H, van Duijn, E, Mattevi, A, van Berkel, W.J.H. 登録日 2013-04-21 公開日 2013-07-24 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.47 Å) 主引用文献 Crystal Structure of 3-Hydroxybenzoate 6-Hydroxylase Uncovers Lipid-Assisted Flavoprotein Strategy for Regioselective Aromatic Hydroxylation J.Biol.Chem., 288, 2013
4BK3	Crystal structure of 3-hydroxybenzoate 6-hydroxylase uncovers lipid- assisted flavoprotein strategy for regioselective aromatic hydroxylation: Y105F mutant 分子名称: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, PHOSPHATIDYLGLYCEROL-PHOSPHOGLYCEROL, ... 著者 Orru, R, Montersino, S, Barendregt, A, Westphal, A.H, van Duijn, E, Mattevi, A, van Berkel, W.J.H. 登録日 2013-04-21 公開日 2013-07-24 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Crystal Structure of 3-Hydroxybenzoate 6-Hydroxylase Uncovers Lipid-Assisted Flavoprotein Strategy for Regioselective Aromatic Hydroxylation J.Biol.Chem., 288, 2013
6FOZ	The crystal structure of P.fluorescens Kynurenine 3-monooxygenase (KMO) in complex with competitive inhibitor No. 13 分子名称: 5-(3,4-dichlorophenyl)furan-2-carboxylic acid, FLAVIN-ADENINE DINUCLEOTIDE, Kynurenine 3-monooxygenase 著者 Levy, C.W, Leys, D. 登録日 2018-02-08 公開日 2019-08-21 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 A brain-permeable inhibitor of the neurodegenerative disease target kynurenine 3-monooxygenase prevents accumulation of neurotoxic metabolites. Commun Biol, 2, 2019
6FP0	The crystal structure of P.fluorescens Kynurenine 3-monooxygenase (KMO) in complex with competitive inhibitor No. 4 分子名称: (2~{R})-2-[[(2~{R})-5-chloranyl-1-methyl-2,3-dihydroindol-2-yl]carbonylamino]-2-cyclohexyl-ethanoic acid, DI(HYDROXYETHYL)ETHER, FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Levy, C.W, Leys, D. 登録日 2018-02-08 公開日 2019-08-21 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 A brain-permeable inhibitor of the neurodegenerative disease target kynurenine 3-monooxygenase prevents accumulation of neurotoxic metabolites. Commun Biol, 2, 2019
6FOX	The crystal structure of P.fluorescens Kynurenine 3-monooxygenase (KMO) in complex with kynurenine 分子名称: (2S)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid, CALCIUM ION, FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Levy, C.W, Leys, D. 登録日 2018-02-08 公開日 2019-08-21 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 A brain-permeable inhibitor of the neurodegenerative disease target kynurenine 3-monooxygenase prevents accumulation of neurotoxic metabolites. Commun Biol, 2, 2019
6FHO	Crystal structure of pqsL, a probable FAD-dependent monooxygenase from Pseudomonas aeruginosa - new refinement 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Probable FAD-dependent monooxygenase 著者 Belviso, B.D, Drees, S.L, Ernst, S, Jagmann, N, Hennecke, U, Fetzner, S. 登録日 2018-01-15 公開日 2018-04-25 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 PqsL uses reduced flavin to produce 2-hydroxylaminobenzoylacetate, a preferred PqsBC substrate in alkyl quinolone biosynthesis inPseudomonas aeruginosa. J. Biol. Chem., 293, 2018
6FOY	The crystal structure of P.fluorescens Kynurenine 3-monooxygenase (KMO) in complex with competitive inhibitor No. 9 分子名称: 5-[2,3-bis(chloranyl)phenyl]furan-2-carboxylic acid, CALCIUM ION, FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Levy, C.W, Leys, D. 登録日 2018-02-08 公開日 2019-08-21 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 A brain-permeable inhibitor of the neurodegenerative disease target kynurenine 3-monooxygenase prevents accumulation of neurotoxic metabolites. Commun Biol, 2, 2019
6FP1	The crystal structure of P.fluorescens Kynurenine 3-monooxygenase (KMO) in complex with competitive inhibitor No. 1 分子名称: 2-(6-chloranyl-5,7-dimethyl-3-oxidanylidene-1,4-benzoxazin-4-yl)ethanoic acid, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Levy, C.W, Leys, D. 登録日 2018-02-08 公開日 2019-08-21 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 A brain-permeable inhibitor of the neurodegenerative disease target kynurenine 3-monooxygenase prevents accumulation of neurotoxic metabolites. Commun Biol, 2, 2019
6FPH	The crystal structure of P.fluorescens Kynurenine 3-monooxygenase (KMO) in complex with competitive inhibitor No. 1h 分子名称: 6-chloranyl-5,7-dimethyl-4-(1~{H}-1,2,3,4-tetrazol-5-ylmethyl)-1,4-benzoxazin-3-one, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Levy, C.W, Leys, D. 登録日 2018-02-09 公開日 2019-08-21 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 A brain-permeable inhibitor of the neurodegenerative disease target kynurenine 3-monooxygenase prevents accumulation of neurotoxic metabolites. Commun Biol, 2, 2019
5X6R	Crystal structure of Saccharomyces cerevisiae KMO in complex with Ro 61-8048 分子名称: 3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide, FLAVIN-ADENINE DINUCLEOTIDE, Kynurenine 3-monooxygenase 著者 Kim, H.T, Hwang, K.Y. 登録日 2017-02-23 公開日 2018-02-21 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.911 Å) 主引用文献 Structural Basis for Inhibitor-Induced Hydrogen Peroxide Production by Kynurenine 3-Monooxygenase Cell Chem Biol, 25, 2018
1IUS	P-HYDROXYBENZOATE HYDROXYLASE COMPLEXED WITH 4-AMINOBENZOATE AT PH 5.0 分子名称: 4-AMINOBENZOIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, P-HYDROXYBENZOATE HYDROXYLASE 著者 Gatti, D.L, Entsch, B, Ballou, D.P, Ludwig, M.L. 登録日 1995-11-22 公開日 1996-04-03 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 pH-dependent structural changes in the active site of p-hydroxybenzoate hydroxylase point to the importance of proton and water movements during catalysis. Biochemistry, 35, 1996
5X68	Crystal Structure of Human KMO 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Kynurenine 3-monooxygenase 著者 Kim, H.T, Hwang, K.Y. 登録日 2017-02-21 公開日 2018-02-21 最終更新日 2018-05-02 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural Basis for Inhibitor-Induced Hydrogen Peroxide Production by Kynurenine 3-Monooxygenase Cell Chem Biol, 25, 2018
5X6P	Crystal structure of Pseudomonas fluorescens KMO 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Kynurenine 3-monooxygenase 著者 Kim, H.T, Hwang, K.Y. 登録日 2017-02-22 公開日 2018-02-21 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Structural Basis for Inhibitor-Induced Hydrogen Peroxide Production by Kynurenine 3-Monooxygenase Cell Chem Biol, 25, 2018
5Y66	Crystal structure of Pseudomonas fluorescens Kynurenine 3-monooxygenase in complex with L-KYN and Ro61-8048 分子名称: (2S)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid, 3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide, FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Xiang, Y, Gao, J.J, Zhu, D.Y. 登録日 2017-08-10 公開日 2017-12-27 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.34 Å) 主引用文献 Biochemistry and structural studies of kynurenine 3-monooxygenase reveal allosteric inhibition by Ro 61-8048 FASEB J., 32, 2018
5Y7A	Crystal structure of Pseudomonas fluorescens Kynurenine 3-monooxygenase in complex with L-KYN 分子名称: (2S)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, Kynurenine 3-monooxygenase 著者 Xiang, Y, Gao, J.J, Zhu, D.Y. 登録日 2017-08-16 公開日 2017-12-27 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.846 Å) 主引用文献 Biochemistry and structural studies of kynurenine 3-monooxygenase reveal allosteric inhibition by Ro 61-8048 FASEB J., 32, 2018
5Y77	Crystal structure of Pseudomonas fluorescens Kynurenine 3-monooxygenase in complex with L-KYN (seMet derivative) 分子名称: (2S)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, Kynurenine 3-monooxygenase 著者 Xiang, Y, Gao, J.J, Zhu, D.Y. 登録日 2017-08-16 公開日 2017-12-27 最終更新日 2018-04-11 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Biochemistry and structural studies of kynurenine 3-monooxygenase reveal allosteric inhibition by Ro 61-8048 FASEB J., 32, 2018
1K0J	Pseudomonas aeruginosa phbh R220Q in complex with NADPH and free of p-OHB 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, P-HYDROXYBENZOATE HYDROXYLASE, ... 著者 Wang, J, Ortiz-Maldonado, M, Entsch, B, Ballou, D, Gatti, D.L. 登録日 2001-09-19 公開日 2002-02-27 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Protein and ligand dynamics in 4-hydroxybenzoate hydroxylase. Proc.Natl.Acad.Sci.USA, 99, 2002

<123456789>