PDB: 113 件ウェブページステータス検索Chemie searchBIRD

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4D1E	THE CRYSTAL STRUCTURE OF HUMAN MUSCLE ALPHA-ACTININ-2 分子名称: ALPHA-ACTININ-2 著者 Pinotsis, N, Salmazo, A, Sjoeblom, B, Gkougkoulia, E, Djinovic-Carugo, K. 登録日 2014-05-01 公開日 2014-12-10 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 The Structure and Regulation of Human Muscle Alpha-Actinin Cell(Cambridge,Mass.), 159, 2014
3JAR	Cryo-EM structure of GDP-microtubule co-polymerized with EB3 分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Zhang, R, Nogales, E. 登録日 2015-06-19 公開日 2015-08-12 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Mechanistic Origin of Microtubule Dynamic Instability and Its Modulation by EB Proteins. Cell(Cambridge,Mass.), 162, 2015
3JAL	Cryo-EM structure of GMPCPP-microtubule co-polymerized with EB3 分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Microtubule-associated protein RP/EB family member 3, ... 著者 Zhang, R, Nogales, E. 登録日 2015-06-16 公開日 2015-08-12 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Mechanistic Origin of Microtubule Dynamic Instability and Its Modulation by EB Proteins. Cell(Cambridge,Mass.), 162, 2015
3JAK	Cryo-EM structure of GTPgammaS-microtubule co-polymerized with EB3 (merged dataset with and without kinesin bound) 分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Zhang, R, Nogales, E. 登録日 2015-06-16 公開日 2015-08-12 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Mechanistic Origin of Microtubule Dynamic Instability and Its Modulation by EB Proteins. Cell(Cambridge,Mass.), 162, 2015
4TXK	Construct of MICAL-1 containing the monooxygenase and calponin homology domains 分子名称: DI(HYDROXYETHYL)ETHER, FLAVIN-ADENINE DINUCLEOTIDE, Protein-methionine sulfoxide oxidase MICAL1 著者 Alqassim, S.S, Amzel, L.M, Bianchet, M.A. 登録日 2014-07-03 公開日 2015-12-23 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.878 Å) 主引用文献 Structural insights into modulation of MICAL activity by its Calponin Homology (CH) domain To Be Published
4TXI	Construct of MICAL-1 containing the monooxygenase and calponin homology domains 分子名称: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Alqassim, S.S, Amzel, L.M, Bianchet, M.A. 登録日 2014-07-03 公開日 2016-01-13 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.309 Å) 主引用文献 Modulation of MICAL Monooxygenase Activity by its Calponin Homology Domain: Structural and Mechanistic Insights. Sci Rep, 6, 2016
5BVR	Actin binding domain of alpha-actinin from Schizosaccharomyces pombe 分子名称: Alpha-actinin-like protein 1, ZINC ION 著者 Persson, K, Backman, L, Addario, B. 登録日 2015-06-05 公開日 2016-03-23 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.46 Å) 主引用文献 Characterisation of Schizosaccharomyces pombe alpha-actinin. Peerj, 4, 2016
4Z6G	Structure of NT domain 分子名称: Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5, PHOSPHATE ION 著者 Yang, F, Zhang, Y. 登録日 2015-04-05 公開日 2016-04-06 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.654 Å) 主引用文献 In vivo epidermal migration requires focal adhesion targeting of ACF7. Nat Commun, 7, 2016
5A38	Mutations in the Calponin homology domain of Alpha-Actinin-2 affect Actin binding and incorporation in muscle. 分子名称: ALPHA-ACTININ-2 著者 Haywood, N.J, Wolny, M, Trinh, C.H, Shuping, Y, Edwards, T.A, Peckham, M. 登録日 2015-05-27 公開日 2016-06-22 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Hypertrophic Cardiomyopathy Mutations in the Calponin-Homology Domain of Actn2 Affect Actin Binding and Cardiomyocyte Z-Disc Incorporation. Biochem.J., 473, 2016
5A36	Mutations in the Calponin homology domain of Alpha-Actinin-2 affect Actin binding and incorporation in muscle. 分子名称: ALPHA-ACTININ-2 著者 Haywood, N.J, Wolny, M, Trinh, C.H, Shuping, Y, Edwards, T.A, Peckham, M. 登録日 2015-05-27 公開日 2016-06-22 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Hypertrophic Cardiomyopathy Mutations in the Calponin-Homology Domain of Actn2 Affect Actin Binding and Cardiomyocyte Z-Disc Incorporation. Biochem.J., 473, 2016
5A4B	Mutations in the Calponin homology domain of Alpha-Actinin-2 affect Actin binding and incorporation in muscle. 分子名称: HUMAN ALPHA-ACTININ-2 著者 Haywood, N.J, Wolny, M, Trinh, C.H, Shuping, Y, Edwards, T.A, Peckham, M. 登録日 2015-06-05 公開日 2016-06-22 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Hypertrophic Cardiomyopathy Mutations in the Calponin-Homology Domain of Actn2 Affect Actin Binding and Cardiomyocyte Z-Disc Incorporation. Biochem.J., 473, 2016
5A37	Mutations in the Calponin homology domain of Alpha-Actinin-2 affect Actin binding and incorporation in muscle. 分子名称: HUMAN ALPHA-ACTININ-2 著者 Haywood, N.J, Wolny, M, Trinh, C.H, Shuping, Y, Edwards, T.A, Peckham, M. 登録日 2015-05-27 公開日 2016-06-22 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Hypertrophic Cardiomyopathy Mutations in the Calponin-Homology Domain of Actn2 Affect Actin Binding and Cardiomyocyte Z-Disc Incorporation. Biochem.J., 473, 2016
5L0O	IQGAP1 calponin homology domain fragment (CHDF) mutant K161C under oxidizing conditions 分子名称: Ras GTPase-activating-like protein IQGAP1 著者 Liu, J, Worthylake, D. 登録日 2016-07-27 公開日 2016-09-28 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.36 Å) 主引用文献 The IQGAP1 N-Terminus Forms Dimers, and the Dimer Interface Is Required for Binding F-Actin and Calcium-Bound Calmodulin. Biochemistry, 55, 2016
6ANU	Cryo-EM structure of F-actin complexed with the beta-III-spectrin actin-binding domain 分子名称: Actin, cytoplasmic 1, Spectrin beta chain, ... 著者 Wang, F, Orlova, A, Avery, A.W, Hays, T.S, Egelman, E.H. 登録日 2017-08-14 公開日 2017-11-22 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (7 Å) 主引用文献 Structural basis for high-affinity actin binding revealed by a beta-III-spectrin SCA5 missense mutation. Nat Commun, 8, 2017
5NL7	The crystal structure of the Actin Binding Domain (ABD) of alpha actinin from Entamoeba histolytica 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, Calponin homology domain protein putative 著者 Pinotsis, N, Djinovic-Carugo, K, Khan, M.B. 登録日 2017-04-04 公開日 2018-05-16 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.48 Å) 主引用文献 Calcium modulates the domain flexibility and function of an alpha-actinin similar to the ancestral alpha-actinin. Proc.Natl.Acad.Sci.USA, 117, 2020
6D8C	Cryo-EM structure of FLNaABD E254K bound to phalloidin-stabilized F-actin 分子名称: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... 著者 Iwamoto, D.V, Huehn, A.R, Simon, B, Huet-Calderwood, C, Baldassarre, M, Sindelar, C.V, Calderwood, D.A. 登録日 2018-04-26 公開日 2018-09-19 最終更新日 2023-11-15 実験手法 ELECTRON MICROSCOPY (3.54 Å) 主引用文献 Structural basis of the filamin A actin-binding domain interaction with F-actin. Nat. Struct. Mol. Biol., 25, 2018
6MIB	Crystal structure of the ILK ATP-binding deficient mutant (L207W)/alpha-parvin core complex 分子名称: Alpha-parvin, Integrin-linked protein kinase 著者 Fukuda, K, Qin, J. 登録日 2018-09-19 公開日 2018-11-07 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Non-catalytic signaling by pseudokinase ILK for regulating cell adhesion. Nat Commun, 9, 2018
6NF1	Vav1 inhibited by an allosteric inhibitor: Vav1 inhibitors block GEF activity 分子名称: (2S)-3-[(3S)-1-(ethylsulfonyl)piperidin-3-yl]-2-{[3-(4-methylphenyl)imidazo[1,2-a]pyrazin-8-yl]amino}propan-1-ol, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Proto-oncogene vav, ... 著者 Knapp, M.S, Elling, R.A, Ornelas, E. 登録日 2018-12-18 公開日 2019-12-25 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Allosteric Inhibitors of VAV1 Block Guanine Nucleotide Exchange Activity To Be Published
6O31	CRYSTAL STRUCTURE OF THE ACTIN-BINDING DOMAIN OF HUMAN ALPHA-ACTININ-4 分子名称: Alpha-actinin-4 著者 Birrane, G, Feng, D. 登録日 2019-02-25 公開日 2020-02-26 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.51 Å) 主引用文献 Phosphorylation of ACTN4 Leads to Podocyte Vulnerability and Proteinuric Glomerulosclerosis. J. Am. Soc. Nephrol., 31, 2020
6ICI	Crystal structure of human MICAL3 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, [F-actin]-monooxygenase MICAL3 著者 Hwang, K.Y, Kim, J.S. 登録日 2018-09-06 公開日 2020-03-04 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural and kinetic insights into flavin-containing monooxygenase and calponin-homology domains in human MICAL3. Iucrj, 7, 2020
6OA6	CRYSTAL STRUCTURE OF THE ACTIN-BINDING DOMAIN OF HUMAN ALPHA-ACTININ-4 分子名称: Alpha-actinin-4, GLYCEROL 著者 Birrane, G, Feng, D. 登録日 2019-03-15 公開日 2020-03-18 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.37 Å) 主引用文献 Phosphorylation of ACTN4 Leads to Podocyte Vulnerability and Proteinuric Glomerulosclerosis. J. Am. Soc. Nephrol., 31, 2020
6M5G	F-actin-Utrophin complex 分子名称: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... 著者 Kumari, A, Ragunath, V.K, Sirajuddin, M. 登録日 2020-03-10 公開日 2020-05-20 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structural insights into actin filament recognition by commonly used cellular actin markers. Embo J., 39, 2020
6SL2	ALPHA-ACTININ FROM ENTAMOEBA HISTOLYTICA 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, Calponin homology domain protein putative, ... 著者 Pinotsis, N, Khan, M.B, Djinovic-Carugo, K. 登録日 2019-08-18 公開日 2020-08-26 最終更新日 2020-11-04 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Calcium modulates the domain flexibility and function of an alpha-actinin similar to the ancestral alpha-actinin. Proc.Natl.Acad.Sci.USA, 117, 2020
6SL7	The Delta Calcium mutant of ALPHA-ACTININ FROM ENTAMOEBA HISTOLYTICA 分子名称: Calponin homology domain protein putative 著者 Pinotsis, N, Lopez Arolas, A, Djinovic-Carugo, K. 登録日 2019-08-18 公開日 2020-08-26 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Calcium modulates the domain flexibility and function of an alpha-actinin similar to the ancestral alpha-actinin. Proc.Natl.Acad.Sci.USA, 117, 2020
6SL3	ALPHA-ACTININ FROM ENTAMOEBA HISTOLYTICA in orthorhombic space group 分子名称: CALCIUM ION, Calponin homology domain protein putative 著者 Pinotsis, N, Khan, M.B, Djinovic-Carugo, K. 登録日 2019-08-18 公開日 2020-08-26 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Calcium modulates the domain flexibility and function of an alpha-actinin similar to the ancestral alpha-actinin. Proc.Natl.Acad.Sci.USA, 117, 2020

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