5NL7

The crystal structure of the Actin Binding Domain (ABD) of alpha actinin from Entamoeba histolytica

Summary for 5NL7

Entry DOI	10.2210/pdb5nl7/pdb
Descriptor	Calponin homology domain protein putative, CALCIUM ION, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (4 entities in total)
Functional Keywords	actin binding domain, actinin, entamoeba histolytica, structural protein
Biological source	Entamoeba histolytica
Total number of polymer chains	2
Total formula weight	53027.56
Authors	Pinotsis, N.,Djinovic-Carugo, K.,Khan, M.B. (deposition date: 2017-04-04, release date: 2018-05-16, Last modification date: 2024-01-17)
Primary citation	Pinotsis, N.,Zielinska, K.,Babuta, M.,Arolas, J.L.,Kostan, J.,Khan, M.B.,Schreiner, C.,Salmazo, A.,Ciccarelli, L.,Puchinger, M.,Gkougkoulia, E.A.,Ribeiro Jr., E.A.,Marlovits, T.C.,Bhattacharya, A.,Djinovic-Carugo, K. Calcium modulates the domain flexibility and function of an alpha-actinin similar to the ancestral alpha-actinin. Proc.Natl.Acad.Sci.USA, 117:22101-22112, 2020 Cited by PubMed: 32848067 DOI: 10.1073/pnas.1917269117 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.48 Å)

Structure validation