8D3U
 
 | | Human alpha3 Na+/K+-ATPase in its Na+-occluded state | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, FXYD domain-containing ion transport regulator 6, Sodium/potassium-transporting ATPase subunit alpha-3, ... | | 著者 | Nguyen, P.T, Bai, X. | | 登録日 | 2022-06-01 | | 公開日 | 2022-09-21 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Structural basis for gating mechanism of the human sodium-potassium pump.
Nat Commun, 13, 2022
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8D3V
 | | Human alpha3 Na+/K+-ATPase in its cytoplasmic side-open state | | 分子名称: | FXYD domain-containing ion transport regulator 6, Sodium/potassium-transporting ATPase subunit alpha-3, Sodium/potassium-transporting ATPase subunit beta-1 | | 著者 | Nguyen, P.T, Bai, X. | | 登録日 | 2022-06-01 | | 公開日 | 2022-09-21 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structural basis for gating mechanism of the human sodium-potassium pump.
Nat Commun, 13, 2022
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8D3X
 | | Human alpha3 Na+/K+-ATPase in its K+-occluded state | | 分子名称: | FXYD domain-containing ion transport regulator 6, Sodium/potassium-transporting ATPase subunit alpha-3, Sodium/potassium-transporting ATPase subunit beta-1, ... | | 著者 | Nguyen, P.T, Bai, X. | | 登録日 | 2022-06-01 | | 公開日 | 2022-09-21 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Structural basis for gating mechanism of the human sodium-potassium pump.
Nat Commun, 13, 2022
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5XAB
 | | Complete structure factors and an atomic model of the calcium pump (SERCA1A) and associated phospholipids in the E2(TG) crystals | | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, OCTANOIC ACID [3S-[3ALPHA, 3ABETA, ... | | 著者 | Norimatsu, Y, Hasegawa, K, Shimizu, N, Toyoshima, C. | | 登録日 | 2017-03-11 | | 公開日 | 2017-06-07 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Protein-phospholipid interplay revealed with crystals of a calcium pump.
Nature, 545, 2017
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8D3Y
 | | Human alpha3 Na+/K+-ATPase in its exoplasmic side-open state | | 分子名称: | FXYD domain-containing ion transport regulator 6, Sodium/potassium-transporting ATPase subunit alpha-3, Sodium/potassium-transporting ATPase subunit beta-1 | | 著者 | Nguyen, P.T, Bai, X. | | 登録日 | 2022-06-01 | | 公開日 | 2022-09-21 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Structural basis for gating mechanism of the human sodium-potassium pump.
Nat Commun, 13, 2022
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8D3W
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6LKN
 | | Crystal structure of ATP11C-CDC50A in PtdSer-bound E2P state | | 分子名称: | 1-deoxy-alpha-D-mannopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, Cell cycle control protein 50A, ... | | 著者 | Abe, K, Irie, K, Nakanishi, H, Hasegawa, K. | | 登録日 | 2019-12-19 | | 公開日 | 2020-06-10 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.9 Å) | | 主引用文献 | Crystal structure of a human plasma membrane phospholipid flippase.
J.Biol.Chem., 295, 2020
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6LN5
 | | CryoEM structure of SERCA2b T1032stop in E1-2Ca2+-AMPPCP (class1) | | 分子名称: | CALCIUM ION, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... | | 著者 | Zhang, Y, Tsutsumi, A, Watanabe, S, Inaba, K. | | 登録日 | 2019-12-28 | | 公開日 | 2020-08-26 | | 最終更新日 | 2020-09-16 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Cryo-EM structures of SERCA2b reveal the mechanism of regulation by the luminal extension tail.
Sci Adv, 6, 2020
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6LN9
 | | CryoEM structure of SERCA2b T1032stop in E2-BeF3- state (class2) | | 分子名称: | BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 | | 著者 | Zhang, Y, Tsutsumi, A, Watanabe, S, Inaba, K. | | 登録日 | 2019-12-28 | | 公開日 | 2020-08-26 | | 最終更新日 | 2020-09-16 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Cryo-EM structures of SERCA2b reveal the mechanism of regulation by the luminal extension tail.
Sci Adv, 6, 2020
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6LN7
 | | CryoEM structure of SERCA2b T1032stop in E1-2Ca2+-AMPPCP (class3) | | 分子名称: | CALCIUM ION, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... | | 著者 | Zhang, Y, Tsutsumi, A, Watanabe, S, Inaba, K. | | 登録日 | 2019-12-28 | | 公開日 | 2020-08-26 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Cryo-EM structures of SERCA2b reveal the mechanism of regulation by the luminal extension tail.
Sci Adv, 6, 2020
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6LN8
 | | CryoEM structure of SERCA2b T1032stop in E2-BeF3- state (class1) | | 分子名称: | BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 | | 著者 | Zhang, Y, Tsutsumi, A, Watanabe, S, Inaba, K. | | 登録日 | 2019-12-28 | | 公開日 | 2020-08-26 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Cryo-EM structures of SERCA2b reveal the mechanism of regulation by the luminal extension tail.
Sci Adv, 6, 2020
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3IXZ
 | | Pig gastric H+/K+-ATPase complexed with aluminium fluoride | | 分子名称: | Potassium-transporting ATPase alpha, Potassium-transporting ATPase subunit beta | | 著者 | Abe, K, Tani, K, Nishizawa, T, Fujiyoshi, Y. | | 登録日 | 2009-03-09 | | 公開日 | 2009-06-23 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (6.5 Å) | | 主引用文献 | Inter-subunit interaction of gastric H+,K+-ATPase prevents reverse reaction of the transport cycle
Embo J., 28, 2009
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3J09
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3J7T
 | | Calcium atpase structure with two bound calcium ions determined by electron crystallography of thin 3D crystals | | 分子名称: | CALCIUM ION, SODIUM ION, Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | | 著者 | Yonekura, K, Kato, K, Ogasawara, M, Tomita, M, Toyoshima, C. | | 登録日 | 2014-08-07 | | 公開日 | 2015-02-18 | | 最終更新日 | 2016-09-28 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (3.4 Å) | | 主引用文献 | Electron crystallography of ultrathin 3D protein crystals: atomic model with charges
Proc.Natl.Acad.Sci.USA, 112, 2015
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3J08
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3KDP
 | | Crystal structure of the sodium-potassium pump | | 分子名称: | CHOLESTEROL, MAGNESIUM ION, Na+/K+ ATPase gamma subunit transcript variant a, ... | | 著者 | Morth, J.P, Pedersen, B.P, Nissen, P. | | 登録日 | 2009-10-23 | | 公開日 | 2010-02-16 | | 最終更新日 | 2017-11-01 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Crystal structure of the sodium-potassium pump.
Nature, 450, 2007
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3NAN
 | | SR Ca(2+)-ATPase in the HnE2 state complexed with a Thapsigargin derivative Boc-(phi)Tg | | 分子名称: | (3S,3aR,4S,6S,6aR,7S,8S,9R,9aS,9bS)-6-(acetyloxy)-4-{[4-(3-{6-[(tert-butoxycarbonyl)amino]hexyl}-4-hydroxyphenyl)butanoyl]oxy}-3,3a-dihydroxy-3,6,9-trimethyl-8-{[(2Z)-2-methylbut-2-enoyl]oxy}-2-oxododecahydroazuleno[4,5-b]furan-7-yl octanoate, MAGNESIUM ION, PHOSPHATIDYLETHANOLAMINE, ... | | 著者 | Winther, A.M.L, Sonntag, Y, Olesen, C, Moller, J.V, Nissen, P. | | 登録日 | 2010-06-02 | | 公開日 | 2010-06-30 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Critical roles of hydrophobicity and orientation of side chains for inactivation of sarcoplasmic reticulum Ca2+-ATPase with thapsigargin and thapsigargin analogs
J.Biol.Chem., 285, 2010
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3N8G
 | | Structure of the (SR)Ca2+-ATPase Ca2-E1-CaAMPPCP form | | 分子名称: | CALCIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, POTASSIUM ION, ... | | 著者 | Bublitz, M, Olesen, C, Poulsen, H, Morth, J.P, Moller, J.V, Nissen, P. | | 登録日 | 2010-05-28 | | 公開日 | 2011-06-08 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.585 Å) | | 主引用文献 | Ion pathways in the sarcoplasmic reticulum Ca2+-ATPase.
J.Biol.Chem., 288, 2013
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3N5K
 | | Structure Of The (Sr)Ca2+-ATPase E2-AlF4- Form | | 分子名称: | ACETATE ION, MAGNESIUM ION, OCTANOIC ACID [3S-[3ALPHA, ... | | 著者 | Bublitz, M, Olesen, C, Poulsen, H, Morth, J.P, Moller, J.V, Nissen, P. | | 登録日 | 2010-05-25 | | 公開日 | 2011-06-08 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Ion pathways in the sarcoplasmic reticulum Ca2+-ATPase.
J.Biol.Chem., 288, 2013
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3N23
 | | Crystal structure of the high affinity complex between ouabain and the E2P form of the sodium-potassium pump | | 分子名称: | MAGNESIUM ION, Na+/K+ ATPase gamma subunit transcript variant a, OUABAIN, ... | | 著者 | Yatime, L, Laursen, M, Morth, J.P, Esmann, M, Nissen, P, Fedosova, N.U. | | 登録日 | 2010-05-17 | | 公開日 | 2011-01-19 | | 最終更新日 | 2014-09-17 | | 実験手法 | X-RAY DIFFRACTION (4.6 Å) | | 主引用文献 | Structural insights into the high affinity binding of cardiotonic steroids to the Na+,K+-ATPase.
J.Struct.Biol., 174, 2011
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3NAL
 | | SR Ca(2+)-ATPase in the HnE2 state complexed with the Thapsigargin derivative DTB | | 分子名称: | (3S,3aR,4S,6S,6aS,8R,9bS)-6-(acetyloxy)-3,3a-dihydroxy-3,6,9-trimethyl-8-{[(2Z)-2-methylbut-2-enoyl]oxy}-2-oxo-2,3,3a,4,5,6,6a,7,8,9b-decahydroazuleno[4,5-b]furan-4-yl dodecanoate, MAGNESIUM ION, POTASSIUM ION, ... | | 著者 | Winther, A.M.L, Sonntag, Y, Olesen, C, Moller, J.V, Nissen, P. | | 登録日 | 2010-06-02 | | 公開日 | 2010-06-30 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Critical roles of hydrophobicity and orientation of side chains for inactivation of sarcoplasmic reticulum Ca2+-ATPase with thapsigargin and thapsigargin analogs
J.Biol.Chem., 285, 2010
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3NAM
 | | SR Ca(2+)-ATPase in the HnE2 state complexed with the Thapsigargin derivative dOTg | | 分子名称: | (3S,3aR,4S,6S,6aS,8R,9R,9aR,9bS)-6-(acetyloxy)-4-(butanoyloxy)-3,3a-dihydroxy-3,6,9-trimethyl-2-oxododecahydroazuleno[4,5-b]furan-8-yl (2Z)-2-methylbut-2-enoate, MAGNESIUM ION, PHOSPHATIDYLETHANOLAMINE, ... | | 著者 | Winther, A.M.L, Sonntag, Y, Olesen, C, Moller, J.V, Nissen, P. | | 登録日 | 2010-06-02 | | 公開日 | 2010-06-30 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Critical roles of hydrophobicity and orientation of side chains for inactivation of sarcoplasmic reticulum Ca2+-ATPase with thapsigargin and thapsigargin analogs
J.Biol.Chem., 285, 2010
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5YLV
 | | Crystal structure of the gastric proton pump complexed with SCH28080 | | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-(2-methyl-8-phenylmethoxy-imidazo[1,2-a]pyridin-3-yl)ethanenitrile, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Abe, K, Irie, K, Nakanishi, H, Fujiyoshi, Y. | | 登録日 | 2017-10-19 | | 公開日 | 2018-04-11 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.79977775 Å) | | 主引用文献 | Crystal structures of the gastric proton pump
Nature, 556, 2018
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5Y0B
 | | PIG GASTRIC H+,K+ - ATPASE IN COMPLEX with BYK99 | | 分子名称: | Potassium-transporting ATPase alpha chain 1, Potassium-transporting ATPase subunit beta | | 著者 | Abe, K, Shimokawa, J, Natio, M, Munson, K, Vagin, O, Sachs, G, Suzuki, H, Tani, K, Fujiyoshi, Y. | | 登録日 | 2017-07-16 | | 公開日 | 2017-08-09 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (6.7 Å) | | 主引用文献 | The cryo-EM structure of gastric H(+),K(+)-ATPase with bound BYK99, a high-affinity member of K(+)-competitive, imidazo[1,2-a]pyridine inhibitors
Sci Rep, 7, 2017
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5YLU
 | | Crystal structure of the gastric proton pump complexed with vonoprazan | | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-[5-(2-fluorophenyl)-1-pyridin-3-ylsulfonyl-pyrrol-3-yl]-~{N}-methyl-methanamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Abe, K, Irie, K, Nakanishi, H, Fujiyoshi, Y. | | 登録日 | 2017-10-19 | | 公開日 | 2018-04-11 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.79988956 Å) | | 主引用文献 | Crystal structures of the gastric proton pump
Nature, 556, 2018
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