3NAN
SR Ca(2+)-ATPase in the HnE2 state complexed with a Thapsigargin derivative Boc-(phi)Tg
Summary for 3NAN
Entry DOI | 10.2210/pdb3nan/pdb |
Related | 2BY4 2C8K 3NAL 3NAM |
Descriptor | SERCA1a, POTASSIUM ION, MAGNESIUM ION, ... (5 entities in total) |
Functional Keywords | serca, p-type atpase, ca2+-atpase, thapsigargin, prostate cancer, calcium transport, endoplasmic reticulum, hydrolase, ion transport, sarcoplasmic reticulum, transmembrane, transport |
Biological source | Oryctolagus cuniculus (rabbit) |
Total number of polymer chains | 1 |
Total formula weight | 111344.17 |
Authors | Winther, A.M.L.,Sonntag, Y.,Olesen, C.,Moller, J.V.,Nissen, P. (deposition date: 2010-06-02, release date: 2010-06-30, Last modification date: 2023-11-01) |
Primary citation | Winther, A.M.L.,Liu, H.,Sonntag, Y.,Olesen, C.,le Maire, M.,Soehoel, H.,Olsen, C.E.,Christensen, S.B.,Nissen, P.,Moller, J.V. Critical roles of hydrophobicity and orientation of side chains for inactivation of sarcoplasmic reticulum Ca2+-ATPase with thapsigargin and thapsigargin analogs J.Biol.Chem., 285:28883-28892, 2010 Cited by PubMed: 20551329DOI: 10.1074/jbc.M110.136242 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.1 Å) |
Structure validation
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