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1N19
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BU of 1n19 by Molmil
Structure of the HSOD A4V mutant
分子名称: COPPER (I) ION, SULFATE ION, Superoxide Dismutase [Cu-Zn], ...
著者Cardoso, R.M.F, Thayer, M.M, DiDonato, M, Lo, T.P, Bruns, C.K, Getzoff, E.D, Tainer, J.A.
登録日2002-10-16
公開日2002-11-27
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Insights into Lou Gehrig's disease from the structure and instability of the A4V mutant of human Cu,Zn superoxide dismutase.
J.Mol.Biol., 324, 2002
1N18
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BU of 1n18 by Molmil
Thermostable mutant of Human Superoxide Dismutase, C6A, C111S
分子名称: COPPER (I) ION, SULFATE ION, Superoxide dismutase [Cu-Zn], ...
著者Cardoso, R.M.F, Thayer, M.M, DiDonato, M, Lo, T.P, Bruns, C.K, Getzoff, E.D, Tainer, J.A.
登録日2002-10-16
公開日2002-11-27
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Insights into Lou Gehrig's disease from the structure and instability of the A4V mutant of human Cu,Zn superoxide dismutase.
J.Mol.Biol., 324, 2002
7VZF
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BU of 7vzf by Molmil
Cryo-EM structure of amyloid fibril formed by full-length human SOD1
分子名称: Superoxide dismutase [Cu-Zn]
著者Wang, L.Q, Ma, Y.Y, Yuan, H.Y, Zhao, K, Zhang, M.Y, Wang, Q, Huang, X, Xu, W.C, Chen, J, Li, D, Zhang, D.L, Zou, L.Y, Yin, P, Liu, C, Liang, Y.
登録日2021-11-16
公開日2022-06-29
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (2.95 Å)
主引用文献Cryo-EM structure of an amyloid fibril formed by full-length human SOD1 reveals its conformational conversion.
Nat Commun, 13, 2022
8JD8
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BU of 8jd8 by Molmil
Crystal structure of Citrus limon Cu-Zn superoxide dismutase
分子名称: COPPER (II) ION, Superoxide dismutase [Cu-Zn], ZINC ION
著者Utami, R.A, Yoshida, H, Retnoningrum, D.S, Ismaya, W.T.
登録日2023-05-12
公開日2023-12-27
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Direct relationship between dimeric form and activity in the acidic copper-zinc superoxide dismutase from lemon.
Acta Crystallogr.,Sect.F, 79, 2023
7WWY
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BU of 7wwy by Molmil
M117L variant of Cu/Zn-superoxide dismutase from dog (Canis familiaris)
分子名称: COPPER (II) ION, Superoxide dismutase [Cu-Zn], ZINC ION
著者Narikiyo, S, Furukawa, Y, Akutsu, M.
登録日2022-02-14
公開日2023-02-15
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Intrinsic structural vulnerability in the hydrophobic core induces species-specific aggregation of canine SOD1 with degenerative myelopathy-linked E40K mutation.
J.Biol.Chem., 299, 2023
7WWT
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BU of 7wwt by Molmil
Cu/Zn-superoxide dismutase from dog (Canis familiaris)
分子名称: COPPER (II) ION, Superoxide dismutase [Cu-Zn], ZINC ION
著者Narikiyo, S, Furukawa, Y, Akutsu, M.
登録日2022-02-14
公開日2023-02-15
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Intrinsic structural vulnerability in the hydrophobic core induces species-specific aggregation of canine SOD1 with degenerative myelopathy-linked E40K mutation.
J.Biol.Chem., 299, 2023
7WX0
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BU of 7wx0 by Molmil
E40K variant of Cu/Zn-superoxide dismutase from dog (Canis familiaris)
分子名称: COPPER (II) ION, Superoxide dismutase [Cu-Zn], ZINC ION
著者Narikiyo, S, Furukawa, Y, Akutsu, M.
登録日2022-02-14
公開日2023-02-15
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Intrinsic structural vulnerability in the hydrophobic core induces species-specific aggregation of canine SOD1 with degenerative myelopathy-linked E40K mutation.
J.Biol.Chem., 299, 2023
7WX1
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BU of 7wx1 by Molmil
E40K/M117L variant of Cu/Zn-superoxide dismutase from dog (Canis familiaris)
分子名称: COPPER (II) ION, Superoxide dismutase [Cu-Zn], ZINC ION
著者Narikiyo, S, Furukawa, Y, Akutsu, M.
登録日2022-02-14
公開日2023-02-15
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Intrinsic structural vulnerability in the hydrophobic core induces species-specific aggregation of canine SOD1 with degenerative myelopathy-linked E40K mutation.
J.Biol.Chem., 299, 2023
2E47
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BU of 2e47 by Molmil
Crystal Structure Analysis of the clock protein EA4 (glycosylation form)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COPPER (II) ION, Time interval measuring enzyme TIME, ...
著者Park, S.-Y, Hiraki, T.
登録日2006-12-05
公開日2007-12-11
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献the clock protein EA4 ticks away with movement of a mobile copper ion
To be Published
7XX3
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BU of 7xx3 by Molmil
Crystal structure of human Superoxide Dismutase (SOD1) in complex with a fungal metabolite molecule, Phialomustin B (PB)
分子名称: (2~{E},4~{E},6~{S})-4,6-dimethyldeca-2,4-dienoic acid, DIMETHYL SULFOXIDE, GLYCEROL, ...
著者Padmanabhan, B, Unni, S.
登録日2022-05-28
公開日2023-12-13
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Phialomustin-B a fungal metabolite isolated from Phialophora mustea modulates Superoxide Dismutase 1 (SOD1) aggregation: Therapeutic potential in Amyotrophic lateral sclerosis (ALS)
To Be Published
2E46
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BU of 2e46 by Molmil
Crystal Structure Analysis of the clock protein EA4
分子名称: COPPER (II) ION, Time interval measuring enzyme TIME, ZINC ION
著者Park, S.-Y, Hiraki, T.
登録日2006-12-05
公開日2008-02-05
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献the clock protein EA4 ticks away with movement of a mobile copper ion
To be Published
5J0G
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BU of 5j0g by Molmil
Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form, circular permutant P7/8
分子名称: OXIDOREDUCTASE,Superoxide dismutase [Cu-Zn]
著者Wang, H, Lang, L, Logan, D, Danielsson, J, Oliveberg, M.
登録日2016-03-28
公開日2017-02-01
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Tricking a Protein To Swap Strands.
J. Am. Chem. Soc., 138, 2016
5IN2
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BU of 5in2 by Molmil
Crystal structure of extra cellular Cu/Zn Superoxide Dismutase from Onchocerca volvulus at 1.5 Angstrom; Insight into novel binding site and new inhibitors
分子名称: AZIDE ION, CHLORIDE ION, COPPER (II) ION, ...
著者Moustafa, A, Betzel, C, Perbandt, M.
登録日2016-03-07
公開日2017-03-29
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Crystal structure of extracellular Cu/Zn Superoxide Dismutase from Onchocerca volvulus at 1.5 Angstrom; Insight into novel binding site and new inhibitors
To Be Published
8K3L
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BU of 8k3l by Molmil
SOD1 and Nanobody3 complex
分子名称: COPPER (II) ION, NB3, Superoxide dismutase [Cu-Zn], ...
著者Cheng, S, Liu, R, Ding, Y.
登録日2023-07-16
公開日2024-07-17
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献SOD1 and Nanobody1 complex
To Be Published
8K33
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BU of 8k33 by Molmil
SOD1 and Nanobody1 complex
分子名称: NB1, Superoxide dismutase [Cu-Zn], ZINC ION
著者Cheng, S.
登録日2023-07-14
公開日2024-07-17
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献SOD1 and Nanobody1 complex
To Be Published
2C9V
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BU of 2c9v by Molmil
Atomic resolution structure of Cu-Zn Human Superoxide dismutase
分子名称: COPPER (II) ION, SODIUM ION, SULFATE ION, ...
著者Strange, R.W, Antonyuk, S.V, Hough, M.A, Doucette, P.A, Valentine, J.S, Hasnain, S.S.
登録日2005-12-14
公開日2005-12-20
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.07 Å)
主引用文献Variable Metallation of Human Superoxide Dismutase: Atomic Resolution Crystal Structures of Cu-Zn, Zn-Zn and as-Isolated Wild-Type Enzymes.
J.Mol.Biol., 356, 2006
8K3A
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BU of 8k3a by Molmil
SOD1 and Nanobody2 complex
分子名称: NB2, Superoxide dismutase [Cu-Zn], ZINC ION
著者Cheng, S.
登録日2023-07-14
公開日2024-07-17
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.74 Å)
主引用文献SOD1 and Nanobody1 complex
To Be Published
5J07
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BU of 5j07 by Molmil
Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form, circular permutant P1/2
分子名称: Superoxide dismutase [Cu-Zn],Superoxide dismutase [Cu-Zn],Superoxide dismutase [Cu-Zn],Superoxide dismutase [Cu-Zn]
著者Wang, H, Lang, L, Logan, D, Danielsson, J, Oliveberg, M.
登録日2016-03-27
公開日2017-02-01
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Tricking a Protein To Swap Strands.
J. Am. Chem. Soc., 138, 2016
5J0C
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BU of 5j0c by Molmil
Monomeric Human Cu,Zn Superoxide dismutase, loops IV and VII deleted, apo form, circular permutant P2/3
分子名称: Superoxide dismutase [Cu-Zn],Superoxide dismutase [Cu-Zn],OXIDOREDUCTASE,Superoxide dismutase [Cu-Zn]
著者Wang, H, Lang, L, Logan, D, Danielsson, J, Oliveberg, M.
登録日2016-03-28
公開日2017-02-01
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Tricking a Protein To Swap Strands.
J. Am. Chem. Soc., 138, 2016
8IHU
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BU of 8ihu by Molmil
Cryo-EM structure of an amyloid fibril formed by ALS-causing SOD1 mutation G85R
分子名称: Superoxide dismutase [Cu-Zn]
著者Wang, L.Q, Ma, Y.Y, Zhang, M.Y, Yuan, H.Y, Li, X.N, Zhao, K, Chen, J, Li, D, Wang, Z.Z, Le, W.D, Liu, C, Liang, Y.
登録日2023-02-23
公開日2024-10-30
実験手法ELECTRON MICROSCOPY (2.97 Å)
主引用文献Amyloid fibril structures and ferroptosis activation induced by ALS-causing SOD1 mutations.
Sci Adv, 2024
8IHV
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BU of 8ihv by Molmil
Cryo-EM structure of an amyloid fibril formed by ALS-causing SOD1 mutation H46R
分子名称: Superoxide dismutase [Cu-Zn]
著者Wang, L.Q, Ma, Y.Y, Zhang, M.Y, Yuan, H.Y, Li, X.N, Zhao, K, Chen, J, Li, D, Wang, Z.Z, Le, W.D, Liu, C, Liang, Y.
登録日2023-02-23
公開日2024-10-30
実験手法ELECTRON MICROSCOPY (3.11 Å)
主引用文献Amyloid fibril structures and ferroptosis activation induced by ALS-causing SOD1 mutations.
Sci Adv, 2024
5KBL
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BU of 5kbl by Molmil
Candida Albicans Superoxide Dismutase 5 (SOD5), E110Q Mutant
分子名称: COPPER (I) ION, Cell surface Cu-only superoxide dismutase 5, SULFATE ION
著者Galaleldeen, A, Peterson, R.L, Villarreal, J, Taylor, A.B, Hart, P.J.
登録日2016-06-03
公開日2016-08-24
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.414 Å)
主引用文献The Phylogeny and Active Site Design of Eukaryotic Copper-only Superoxide Dismutases.
J.Biol.Chem., 291, 2016
5K02
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BU of 5k02 by Molmil
Structure of human SOD1 with T2D mutation
分子名称: COPPER (II) ION, Superoxide dismutase [Cu-Zn], ZINC ION
著者Fay, J.M, Zhu, C, Cui, W, Ke, H, Dokholyan, N.V.
登録日2016-05-17
公開日2016-11-23
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献A Phosphomimetic Mutation Stabilizes SOD1 and Rescues Cell Viability in the Context of an ALS-Associated Mutation.
Structure, 24, 2016
2C9S
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BU of 2c9s by Molmil
1.24 Angstroms resolution structure of Zn-Zn Human Superoxide dismutase
分子名称: ACETATE ION, SULFATE ION, SUPEROXIDE DISMUTASE [CU-ZN], ...
著者Strange, R.W, Antonyuk, S.V, Hough, M.A, Doucette, P.A, Valentine S, J.S, Hasnain, S.
登録日2005-12-14
公開日2005-12-15
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.24 Å)
主引用文献Variable Metallation of Human Superoxide Dismutase: Atomic Resolution Crystal Structures of Cu-Zn, Zn-Zn and as-Isolated Wild-Type Enzymes.
J.Mol.Biol., 356, 2006
8IQ0
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BU of 8iq0 by Molmil
Crystal structure of hydrogen sulfide-bound superoxide dismutase in oxidized state
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, COPPER (II) ION, ...
著者Zhou, J.H, Huang, W.X, Cheng, R.X, Zhang, P.J, Zhu, Y.C.
登録日2023-03-15
公開日2023-09-06
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Hydrogen sulfide functions as a micro-modulator bound at the copper active site of Cu/Zn-SOD to regulate the catalytic activity of the enzyme.
Cell Rep, 42, 2023

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