PDB: 594 件ウェブページステータス検索Chemie searchBIRD

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1FHS	THE THREE-DIMENSIONAL SOLUTION STRUCTURE OF THE SRC HOMOLOGY DOMAIN-2 OF THE GROWTH FACTOR RECEPTOR BOUND PROTEIN-2, NMR, 18 STRUCTURES 分子名称: GROWTH FACTOR RECEPTOR BOUND PROTEIN-2 著者 Senior, M.M, Frederick, A.F, Black, S, Perkins, L.M, Wilson, O, Snow, M.E, Wang, Y.-S. 登録日 1997-06-12 公開日 1998-06-17 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 The three-dimensional solution structure of the Src homology domain-2 of the growth factor receptor-bound protein-2. J.Biomol.NMR, 11, 1998
1FU6	NMR STRUCTURE OF THE N-SH2 DOMAIN OF THE P85 SUBUNIT OF PI3-KINASE 分子名称: PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY ALPHA SUBUNIT 著者 Weber, T, Schaffhausen, B, Liu, Y, Guenther, U.L. 登録日 2000-09-14 公開日 2001-02-21 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 NMR structure of the N-SH2 of the p85 subunit of phosphoinositide 3-kinase complexed to a doubly phosphorylated peptide reveals a second phosphotyrosine binding site. Biochemistry, 39, 2000
1FU5	NMR STRUCTURE OF THE N-SH2 DOMAIN OF THE P85 SUBUNIT OF PI3-KINASE COMPLEXED TO A DOUBLY PHOSPHORYLATED PEPTIDE DERIVED FROM POLYOMAVIRUS MIDDLE T ANTIGEN 分子名称: DOUBLY PHOSPHORYLATED MIDDLE T ANTIGEN, PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY ALPHA SUBUNIT 著者 Weber, T, Schaffhausen, B, Liu, Y, Guenther, U.L. 登録日 2000-09-14 公開日 2001-02-21 最終更新日 2022-02-23 実験手法 SOLUTION NMR 主引用文献 NMR structure of the N-SH2 of the p85 subunit of phosphoinositide 3-kinase complexed to a doubly phosphorylated peptide reveals a second phosphotyrosine binding site. Biochemistry, 39, 2000
1FYR	DIMER FORMATION THROUGH DOMAIN SWAPPING IN THE CRYSTAL STRUCTURE OF THE GRB2-SH2 AC-PYVNV COMPLEX 分子名称: GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2, HEPATOCYTE GROWTH FACTOR RECEPTOR PEPTIDE 著者 Schiering, N, Casale, E, Caccia, P, Giordano, P, Battistini, C. 登録日 2000-10-03 公開日 2000-12-06 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Dimer formation through domain swapping in the crystal structure of the Grb2-SH2-Ac-pYVNV complex. Biochemistry, 39, 2000
1GHU	NMR solution structure of growth factor receptor-bound protein 2 (GRB2) SH2 domain, 24 structures 分子名称: GRB2 著者 Thornton, K.H, Mueller, W.T, Mcconnell, P, Zhu, G, Saltiel, A.R, Thanabal, V. 登録日 1996-08-05 公開日 1997-01-27 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Nuclear magnetic resonance solution structure of the growth factor receptor-bound protein 2 Src homology 2 domain. Biochemistry, 35, 1996
1ZFP	GROWTH FACTOR RECEPTOR BINDING PROTEIN SH2 DOMAIN COMPLEXED WITH A PHOSPHOTYROSYL PENTAPEPTIDE 分子名称: EPIDERMAL GROWTH FACTOR RECEPTOR-DERIVED PEPTIDE, GROWTH FACTOR RECEPTOR BINDING PROTEIN, ZINC ION 著者 Rahuel, J. 登録日 1998-03-26 公開日 1999-03-30 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural basis for the high affinity of amino-aromatic SH2 phosphopeptide ligands. J.Mol.Biol., 279, 1998
3MAZ	Crystal Structure of the Human BRDG1/STAP-1 SH2 Domain in Complex with the NTAL pTyr136 Peptide 分子名称: CheD family protein, MALONATE ION, Signal-transducing adaptor protein 1 著者 Kaneko, T, Huang, H, Zhao, B, Li, L, Liu, H, Voss, C.K, Wu, C, Schiller, M.R, Li, S.S. 登録日 2010-03-24 公開日 2010-05-12 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Loops govern SH2 domain specificity by controlling access to binding pockets. Sci.Signal., 3, 2010
1Z3K	Structural Insight into the Binding Diversity between the Tyr-Phosphorylated Human EphrinBs and Nck2 SH2 Domain 分子名称: Cytoplasmic protein NCK2 著者 Ran, X, Song, J. 登録日 2005-03-14 公開日 2005-03-29 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Structural insight into the binding diversity between the Tyr-phosphorylated human ephrinBs and Nck2 SH2 domain. J.Biol.Chem., 280, 2005
3MXC	Structures of Grb2-SH2 Domain and AICD peptide Complexes Reveal a Conformational Switch and Their Functional Implications. 分子名称: AICD peptide, Growth factor receptor-bound protein 2 著者 Sen, U, Das, S. 登録日 2010-05-07 公開日 2011-05-11 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Functional Implications of the Conformational Switch in AICD Peptide upon Binding to Grb2-SH2 Domain. J.Mol.Biol., 414, 2011
1HCT	NMR STRUCTURE OF THE HUMAN SRC SH2 DOMAIN COMPLEX 分子名称: ACETYL-PYEEIE-OH, HUMAN SRC 著者 Gampe Junior, R.T, Xu, R.X. 登録日 1994-09-02 公開日 1995-09-15 最終更新日 2022-02-23 実験手法 SOLUTION NMR 主引用文献 Solution structure of the human pp60c-src SH2 domain complexed with a phosphorylated tyrosine pentapeptide. Biochemistry, 34, 1995
3MXY	Structures of Grb2-SH2 Domain and AICD peptide Complexes Reveal a Conformational Switch and Their Functional Implications. 分子名称: AICD peptide E683V variant, Growth factor receptor-bound protein 2 著者 Sen, U, Das, S. 登録日 2010-05-08 公開日 2011-05-11 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Functional Implications of the Conformational Switch in AICD Peptide upon Binding to Grb2-SH2 Domain. J.Mol.Biol., 414, 2011
1HCS	NMR STRUCTURE OF THE HUMAN SRC SH2 DOMAIN COMPLEX 分子名称: ACETYL-PYEEIE-OH, HUMAN SRC 著者 Gampe Junior, R.T, Xu, R.X. 登録日 1994-09-02 公開日 1995-09-15 最終更新日 2022-02-23 実験手法 SOLUTION NMR 主引用文献 Solution structure of the human pp60c-src SH2 domain complexed with a phosphorylated tyrosine pentapeptide. Biochemistry, 34, 1995
1H9O	PHOSPHATIDYLINOSITOL 3-KINASE, P85-ALPHA SUBUNIT: C-TERMINAL SH2 DOMAIN COMPLEXED WITH A TYR751 PHOSPHOPEPTIDE FROM THE PDGF RECEPTOR, CRYSTAL STRUCTURE AT 1.79 A 分子名称: BETA-PLATELET-DERIVED GROWTH FACTOR RECEPTOR, PHOSPHATIDYLINOSITOL 3-KINASE 著者 Pauptit, R.A, Rowsell, S, Breeze, A.L, Murshudov, G.N, Dennis, C.A, Derbyshire, D.J, Weston, S.A. 登録日 2001-03-14 公開日 2001-03-19 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 NMR Trial Models: Experiences with the Colicin Immunity Protein Im7 and the P85Alpha C-Terminal Sh2-Peptide Complex Acta Crystallogr.,Sect.D, 57, 2001
3N8M	Crystal Structure of the Grb2 SH2 Domain in Complex with An Acyclic Ligand Having the Sequence pYVNVP 分子名称: GLYCEROL, Growth factor receptor-bound protein 2, PEPTIDE 著者 Whiddon, B.B, Clements, J.H, Martin, S.F. 登録日 2010-05-28 公開日 2010-12-15 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Thermodynamic and Structural Effects of Macrocyclization as a Constraining Method in Protein-Ligand Interactions. ACS MED.CHEM.LETT., 1, 2010
1X6C	Solution structures of the SH2 domain of human protein-tyrosine phosphatase SHP-1 分子名称: Tyrosine-protein phosphatase, non-receptor type 6 著者 Sato, M, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2005-05-17 公開日 2005-11-17 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structures of the SH2 domain of human protein-tyrosine phosphatase SHP-1 To be Published
3OV1	Crystal Structure of the Grb2 SH2 Domain in Complex with a pYXN-Derived Tripeptide 分子名称: FORMIC ACID, GLYCEROL, Growth factor receptor-bound protein 2, ... 著者 Clements, J.H, Martin, S.F. 登録日 2010-09-15 公開日 2011-11-02 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Protein-ligand interactions: thermodynamic effects associated with increasing nonpolar surface area. J.Am.Chem.Soc., 133, 2011
3N7Y	Crystal Structure of the Grb2 SH2 Domain in Complex with a 20-Membered Macrocyclic Ligand Having the Sequence pYVNV 分子名称: 20-membered peptide-like macrocyclic ligand, Growth factor receptor-bound protein 2 著者 Whiddon, B.B, Clements, J.H, Martin, S.F. 登録日 2010-05-27 公開日 2011-01-12 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 Thermodynamic and Structural Effects of Macrocyclization as a Constraining Method in Protein-Ligand Interactions. ACS MED.CHEM.LETT., 1, 2010
3N84	Crystal Structure of the Grb2 SH2 Domain in Complex with a 23-Membered Macrocyclic Ligand Having the Sequence pYVNVP 分子名称: 23-membered peptide-like macrocyclic ligand, CHLORIDE ION, GLYCEROL, ... 著者 Clements, J.H, Martin, S.F. 登録日 2010-05-27 公開日 2011-01-12 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Thermodynamic and Structural Effects of Macrocyclization as a Constraining Method in Protein-Ligand Interactions. ACS MED.CHEM.LETT., 1, 2010
3OVE	Crystal Structure of the Grb2 SH2 Domain in Complex with a pYXN-Derived Tripeptide 分子名称: CHLORIDE ION, Growth factor receptor-bound protein 2, PYAC7CN 著者 Clements, J.H, Martin, S.F. 登録日 2010-09-16 公開日 2011-11-02 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Protein-ligand interactions: thermodynamic effects associated with increasing nonpolar surface area. J.Am.Chem.Soc., 133, 2011
7RNV	SH2 domain of guanine nucleotide exchange factor Vav2 in complex with an actin peptide with phosphorylated tyrosine 53 分子名称: 1,2-ETHANEDIOL, Actin, alpha skeletal muscle, ... 著者 Dai, S, Horton, J.R, Cheng, X. 登録日 2021-07-29 公開日 2021-08-11 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 The Functional Analysis of a Major Tyrosine Phosphorylation Site on Actin To Be Published
7RNS	nSH2 domain of p85-alpha subunit of phosphatidylinositol 3-kinase in complex with an actin peptide with phosphorylated tyrosine 53 分子名称: 1,2-ETHANEDIOL, Actin, alpha skeletal muscle, ... 著者 Dai, S, Horton, J.R, Cheng, X. 登録日 2021-07-29 公開日 2021-08-11 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.14 Å) 主引用文献 The Functional Analysis of a Major Tyrosine Phosphorylation Site on Actin To Be Published
7RNU	nSH2 domain of p85-beta subunit of phosphatidylinositol 3-kinase in complex with an actin peptide with phosphorylated tyrosine 53 分子名称: 1,2-ETHANEDIOL, Actin, alpha skeletal muscle, ... 著者 Dai, S, Horton, J.R, Cheng, X. 登録日 2021-07-29 公開日 2021-08-11 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 The Functional Analysis of a Major Tyrosine Phosphorylation Site on Actin To Be Published
7R8X	Crystal Structure of the LNK SH2 Domain in Complex with an EPOR pY454 Phosphopeptide 分子名称: EPOR pY454 phosphopeptide, SH2B adapter protein 3 著者 Morris, R, Kershaw, N.J, Babon, J.J. 登録日 2021-06-27 公開日 2021-10-06 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural and functional analysis of target recognition by the lymphocyte adaptor protein LNK. Nat Commun, 12, 2021
7R8W	Crystal Structure of the LNK SH2 Domain in Complex with a JAK2 pY813 Phosphopeptide 分子名称: JAK2 pY813 phosphopeptide, SH2B adapter protein 3 著者 Morris, R, Kershaw, N.J, Babon, J.J. 登録日 2021-06-27 公開日 2021-10-06 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural and functional analysis of target recognition by the lymphocyte adaptor protein LNK. Nat Commun, 12, 2021
7SA7	Crystal structure of the apo SH2 domains of Syk 分子名称: Tyrosine-protein kinase SYK 著者 Hobbs, H.T, Badroos, J, Gee, C.L, Kuriyan, J. 登録日 2021-09-22 公開日 2021-10-13 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Differences in the dynamics of the tandem-SH2 modules of the Syk and ZAP-70 tyrosine kinases. Protein Sci., 30, 2021

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