7R8W

Crystal Structure of the LNK SH2 Domain in Complex with a JAK2 pY813 Phosphopeptide

Summary for 7R8W

• Entry DOI: 10.2210/pdb7r8w/pdb
• Related: 7R8X
• Descriptor: SH2B adapter protein 3, JAK2 pY813 phosphopeptide (3 entities in total)
• Functional Keywords: lnk, sh2b3, jak/stat, mpns, signaling protein
• Biological source: Mus musculus (Mouse); More
• Total number of polymer chains: 2
• Total formula weight: 13671.69

Authors

Morris, R.,Kershaw, N.J.,Babon, J.J. (deposition date: 2021-06-27, release date: 2021-10-06, Last modification date: 2023-11-15)

• Primary citation: Morris, R.,Zhang, Y.,Ellyard, J.I.,Vinuesa, C.G.,Murphy, J.M.,Laktyushin, A.,Kershaw, N.J.,Babon, J.J.; Structural and functional analysis of target recognition by the lymphocyte adaptor protein LNK.; Nat Commun, 12:6110-6110, 2021; PubMed: 34671038; DOI: 10.1038/s41467-021-26394-6

Experimental method

X-RAY DIFFRACTION (1.9 Å)