PDB: 890 件ウェブページステータス検索Chemie searchBIRD

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5E0K	X-ray crystal structure of tryptophan synthase complex from Pyrococcus furiosus at 2.76 A 分子名称: PHOSPHATE ION, Tryptophan synthase alpha chain, Tryptophan synthase beta chain 1 著者 Buller, A.R, Murciano-Calles, J, Arnold, F.H. 登録日 2015-09-29 公開日 2015-11-11 最終更新日 2019-12-25 実験手法 X-RAY DIFFRACTION (2.76 Å) 主引用文献 Directed evolution of the tryptophan synthase beta-subunit for stand-alone function recapitulates allosteric activation. Proc.Natl.Acad.Sci.USA, 112, 2015
2HH0	Structure of an Anti-PrP Fab, P-Clone, in Complex with its Cognate Bovine Peptide Epitope. 分子名称: Heavy Chain, P-Clone Fab, Chimera, ... 著者 Kanyo, Z.K. 登録日 2006-06-27 公開日 2006-12-26 最終更新日 2017-10-11 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Directed evolution of an anti-prion protein scFv fragment to an affinity of 1 pM and its structural interpretation J.Mol.Biol., 363, 2006
2HQK	Crystal structure of a monomeric cyan fluorescent protein derived from Clavularia 分子名称: ACETATE ION, CHLORIDE ION, Cyan fluorescent chromoprotein, ... 著者 Henderson, J.N, Campbell, R.E, Ai, H, Remington, S.J. 登録日 2006-07-18 公開日 2007-01-02 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.19 Å) 主引用文献 Directed evolution of a monomeric, bright and photostable version of Clavularia cyan fluorescent protein: structural characterization and applications in fluorescence imaging. Biochem.J., 400, 2006
2XQQ	Human dynein light chain (DYNLL2) in complex with an in vitro evolved peptide (Ac-SRGTQTE). 分子名称: ACETATE ION, DYNEIN LIGHT CHAIN 2, CYTOPLASMIC, ... 著者 Rapali, P, Radnai, L, Suveges, D, Hetenyi, C, Harmat, V, Tolgyesi, F, Wahlgren, W.Y, Katona, G, Nyitray, L, Pal, G. 登録日 2010-09-07 公開日 2011-05-04 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.31 Å) 主引用文献 Directed Evolution Reveals the Binding Motif Preference of the Lc8/Dynll Hub Protein and Predicts Large Numbers of Novel Binders in the Human Proteome Plos One, 6, 2011
6AMH	Engineered tryptophan synthase b-subunit from Pyrococcus furiosus, PfTrpB4D11 with Ser bound as E(Aex1) 分子名称: SODIUM ION, Tryptophan synthase beta chain 1, [3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-SERINE 著者 Buller, A.R. 登録日 2017-08-09 公開日 2018-05-16 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 Directed Evolution Mimics Allosteric Activation by Stepwise Tuning of the Conformational Ensemble. J. Am. Chem. Soc., 140, 2018
6AM7	Engineered tryptophan synthase b-subunit from Pyrococcus furiosus, PfTrpB2B9 分子名称: PHOSPHATE ION, SODIUM ION, Tryptophan synthase beta chain 1 著者 Buller, A.R, van Roye, P. 登録日 2017-08-09 公開日 2018-05-16 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.47 Å) 主引用文献 Directed Evolution Mimics Allosteric Activation by Stepwise Tuning of the Conformational Ensemble. J. Am. Chem. Soc., 140, 2018
6AMC	Engineered tryptophan synthase b-subunit from Pyrococcus furiosus, PfTrpB4D11 分子名称: SODIUM ION, Tryptophan synthase beta chain 1 著者 Buller, A.R, Herger, M. 登録日 2017-08-09 公開日 2018-05-16 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Directed Evolution Mimics Allosteric Activation by Stepwise Tuning of the Conformational Ensemble. J. Am. Chem. Soc., 140, 2018
6AMI	Engineered tryptophan synthase b-subunit from Pyrococcus furiosus, PfTrpB4D11 with Trp non-covalently bound 分子名称: SODIUM ION, TRYPTOPHAN, Tryptophan synthase beta chain 1 著者 Buller, A.R. 登録日 2017-08-09 公開日 2018-05-16 最終更新日 2022-03-23 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Directed Evolution Mimics Allosteric Activation by Stepwise Tuning of the Conformational Ensemble. J. Am. Chem. Soc., 140, 2018
6AM9	Engineered tryptophan synthase b-subunit from Pyrococcus furiosus, PfTrpB2B9, with Ser-bound in a predominantly closed state. 分子名称: 2-{[(E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}prop-2-enoic acid, SODIUM ION, Tryptophan synthase beta chain 1, ... 著者 Buller, A.R, van Roye, P. 登録日 2017-08-09 公開日 2018-05-16 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Directed Evolution Mimics Allosteric Activation by Stepwise Tuning of the Conformational Ensemble. J. Am. Chem. Soc., 140, 2018
6AM8	Engineered tryptophan synthase b-subunit from Pyrococcus furiosus, PfTrpB2B9 with Trp bound as E(Aex2) 分子名称: SODIUM ION, TRYPTOPHAN, Tryptophan synthase beta chain 1, ... 著者 Buller, A.R, van Roye, P. 登録日 2017-08-09 公開日 2018-05-16 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Directed Evolution Mimics Allosteric Activation by Stepwise Tuning of the Conformational Ensemble. J. Am. Chem. Soc., 140, 2018
1FQ0	KDPG ALDOLASE FROM ESCHERICHIA COLI 分子名称: CITRIC ACID, KDPG ALDOLASE 著者 Naismith, J.H. 登録日 2000-09-01 公開日 2000-10-04 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Directed evolution of a new catalytic site in 2-keto-3-deoxy-6-phosphogluconate aldolase from Escherichia coli. Structure, 9, 2001
1FWR	CRYSTAL STRUCTURE OF KDPG ALDOLASE DOUBLE MUTANT K133Q/T161K 分子名称: CITRIC ACID, KDPG ALDOLASE 著者 Naismith, J.H, Buchanan, L.V. 登録日 2000-09-24 公開日 2000-10-04 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Directed evolution of a new catalytic site in 2-keto-3-deoxy-6-phosphogluconate aldolase from Escherichia coli. Structure, 9, 2001
5ZOI	Crystal Structure of alpha1,3-Fucosyltransferase 分子名称: Alpha-(1,3)-fucosyltransferase FucT, [[(2S,3R,4S,5R)-5-(2-azanyl-6-oxidanylidene-1H-purin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2S,3S,4S,5R,6R)-6-methyl-3,4,5-tris(oxidanyl)oxan-2-yl] hydrogen phosphate 著者 Tan, Y, Yang, G. 登録日 2018-04-13 公開日 2019-06-26 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (3.19 Å) 主引用文献 Directed evolution of an alpha 1,3-fucosyltransferase using a single-cell ultrahigh-throughput screening method. Sci Adv, 5, 2019
3HLC	Simvastatin Synthase (LovD) from Aspergillus terreus, S5 mutant, unliganded 分子名称: GLYCEROL, TETRAETHYLENE GLYCOL, Transesterase 著者 Sawaya, M.R, Yeates, T.O, Laidman, J, Pashkov, I, Gao, X, Tang, Y. 登録日 2009-05-27 公開日 2009-10-27 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Directed evolution and structural characterization of a simvastatin synthase Chem.Biol., 16, 2009
3HLD	Simvastatin Synthase (LovD), from Aspergillus terreus, S5 mutant complex with monacolin J acid 分子名称: (3R,5R)-3,5-dihydroxy-7-[(1S,2S,6R,8S,8aR)-8-hydroxy-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]heptanoic acid, FORMIC ACID, Transesterase 著者 Sawaya, M.R, Yeates, T.O, Pashkov, I, Gao, X, Tang, Y. 登録日 2009-05-27 公開日 2009-10-27 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Directed evolution and structural characterization of a simvastatin synthase Chem.Biol., 16, 2009
3HLG	Simvastatin Synthase (LovD), from Aspergillus terreus, S5 mutant, S76A mutant, complex with lovastatin 分子名称: (3R,5R)-7-((1R,2R,6S,8R,8AS)-2,6-DIMETHYL-8-{[(2R)-2-METHYLBUTANOYL]OXY}-1,2,6,7,8,8A-HEXAHYDRONAPHTHALEN-1-YL)-3,5-DIHYDROXYHEPTANOIC ACID, Transesterase 著者 Sawaya, M.R, Yeates, T.O, Pashkov, I, Gao, X, Tang, Y. 登録日 2009-05-27 公開日 2009-10-27 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Directed evolution and structural characterization of a simvastatin synthase Chem.Biol., 16, 2009
3HLE	Simvastatin Synthase (LovD), from Aspergillus terreus, S5 mutant, S76A mutant, complex with monacolin J acid 分子名称: (3R,5R)-3,5-dihydroxy-7-[(1S,2S,6R,8S,8aR)-8-hydroxy-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]heptanoic acid, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Transesterase 著者 Sawaya, M.R, Yeates, T.O, Pashkov, I, Gao, X, Tang, Y. 登録日 2009-05-27 公開日 2009-10-27 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.06 Å) 主引用文献 Directed evolution and structural characterization of a simvastatin synthase Chem.Biol., 16, 2009
3HLF	Simvastatin Synthase (LovD), from Aspergillus terreus, S5 mutant, S76A mutant, complex with simvastatin 分子名称: Simvastatin acid, Transesterase 著者 Sawaya, M.R, Yeates, T.O, Pashkov, I, Gao, X, Tang, Y. 登録日 2009-05-27 公開日 2009-10-27 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Directed evolution and structural characterization of a simvastatin synthase Chem.Biol., 16, 2009
3HL9	Simvastatin Synthase (LovD) from Aspergillus terreus, unliganded 分子名称: Transesterase 著者 Sawaya, M.R, Yeates, T.O, Laidman, J, Pashkov, I, Gao, X, Tang, Y. 登録日 2009-05-27 公開日 2009-10-27 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Directed evolution and structural characterization of a simvastatin synthase Chem.Biol., 16, 2009
3HLB	Simvastatin Synthase (LovD) from Aspergillus terreus, unliganded, selenomethionyl derivative 分子名称: SULFATE ION, Transesterase 著者 Sawaya, M.R, Yeates, T.O, Laidman, J, Pashkov, I, Gao, X, Tang, Y. 登録日 2009-05-27 公開日 2009-10-27 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Directed evolution and structural characterization of a simvastatin synthase Chem.Biol., 16, 2009
3P8M	Human dynein light chain (DYNLL2) in complex with an in vitro evolved peptide dimerized by leucine zipper 分子名称: Dynein light chain 2, General control protein GCN4 著者 Rapali, P, Radnai, L, Suveges, D, Hetenyi, C, Harmat, V, Tolgyesi, F, Wahlgren, W.Y, Katona, G, Nyitray, L, Pal, G. 登録日 2010-10-14 公開日 2011-08-31 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Directed evolution reveals the binding motif preference of the LC8/DYNLL hub protein and predicts large numbers of novel binders in the human proteome. Plos One, 6, 2011
3QVV	Crystal structure of Ancestral variant b9 of SULT 1A1 in complex with PAP and 3-CyC 分子名称: 7-hydroxy-2-oxo-2H-chromene-3-carbonitrile, ADENOSINE-3'-5'-DIPHOSPHATE, Sulfotransferase 1A1 著者 Alkolombri, U, Elias, M, Tawfik, D.S. 登録日 2011-02-26 公開日 2011-08-31 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Directed evolution of sulfotransferases and paraoxonases by ancestral libraries. J.Mol.Biol., 411, 2011
3QVU	Crystal structure of Ancestral variant b9 of SULT 1A1 in complex with PAP and p-nitrophenol 分子名称: 1,2-ETHANEDIOL, ADENOSINE-3'-5'-DIPHOSPHATE, P-NITROPHENOL, ... 著者 Alcolombri, U, Elias, M, Tawfik, D.S. 登録日 2011-02-26 公開日 2011-08-31 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Directed evolution of sulfotransferases and paraoxonases by ancestral libraries. J.Mol.Biol., 411, 2011
3OJG	Structure of an inactive lactonase from Geobacillus kaustophilus with bound N-butyryl-DL-homoserine lactone 分子名称: FE (III) ION, N-[(3S)-2-oxotetrahydrofuran-3-yl]butanamide, Phosphotriesterase, ... 著者 Xue, B, Chow, J.Y, Tung, A, Robinson, R.C. 登録日 2010-08-22 公開日 2010-10-27 最終更新日 2017-11-08 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Directed evolution of a thermostable quorum-quenching lactonase from the amidohydrolase superfamily J.Biol.Chem., 285, 2010
3VZQ	Crystal structure of Q47L mutant of PhaB from Ralstonia eutropha 分子名称: Acetoacetyl-CoA reductase 著者 Ikeda, K, Tanaka, Y, Tanaka, I, Yao, M. 登録日 2012-10-15 公開日 2013-08-28 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Directed evolution and structural analysis of NADPH-dependent Acetoacetyl Coenzyme A (Acetoacetyl-CoA) reductase from Ralstonia eutropha reveals two mutations responsible for enhanced kinetics Appl.Environ.Microbiol., 79, 2013

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