2HH0
Structure of an Anti-PrP Fab, P-Clone, in Complex with its Cognate Bovine Peptide Epitope.
Summary for 2HH0
Entry DOI | 10.2210/pdb2hh0/pdb |
Descriptor | Light Chain, P-Clone Fab, Chimera, Heavy Chain, P-Clone Fab, Chimera, Prion protein, ... (4 entities in total) |
Functional Keywords | prion, prp, fab, immune system |
Biological source | Mus musculus, Homo sapiens (house mouse, human) More |
Total number of polymer chains | 3 |
Total formula weight | 47366.76 |
Authors | Kanyo, Z.K. (deposition date: 2006-06-27, release date: 2006-12-26, Last modification date: 2017-10-11) |
Primary citation | Luginbuhl, B.,Kanyo, Z.,Jones, R.M.,Fletterick, R.J.,Prusiner, S.B.,Cohen, F.E.,Williamson, R.A.,Burton, D.R.,Pluckthun, A. Directed evolution of an anti-prion protein scFv fragment to an affinity of 1 pM and its structural interpretation J.Mol.Biol., 363:75-97, 2006 Cited by PubMed: 16962610DOI: 10.1016/j.jmb.2006.07.027 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.85 Å) |
Structure validation
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