PDB: 186017 件ウェブページステータス検索Chemie searchBIRD

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8OK9	Heterodimeric complex of Archaeoglobus fulgidus Argonaute protein Af1318 (AfAgo) with DNA and AfAgo-N protein containing N-L1-L2 domains 分子名称: 1,2-ETHANEDIOL, ACETIC ACID, Archaeoglobus fulgidus AfAgo-N protein, ... 著者 Manakova, E.N, Zaremba, M. 登録日 2023-03-27 公開日 2024-01-24 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The missing part: the Archaeoglobus fulgidus Argonaute forms a functional heterodimer with an N-L1-L2 domain protein. Nucleic Acids Res., 52, 2024
8C23	Structure of E. coli Class 2 L-asparaginase EcAIII, mutant M200T (monoclinic form M200T#m) 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, GLYCEROL, ... 著者 Sciuk, A, Ruszkowski, M, Jaskolski, M, Loch, J.I. 登録日 2022-12-21 公開日 2023-05-03 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (1.842 Å) 主引用文献 The effects of nature-inspired amino acid substitutions on structural and biochemical properties of the E. coli L-asparaginase EcAIII. Protein Sci., 32, 2023
7SFV	CryoEM structure of Venezuelan Equine Encephalitis virus (VEEV) TC-83 strain VLP in complex with Fab hVEEV-63 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Capsid protein, Spike glycoprotein E1, ... 著者 Binshtein, E, Crowe, J.E. 登録日 2021-10-04 公開日 2022-03-16 最終更新日 2022-07-06 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Neutralizing antibodies protect mice against Venezuelan equine encephalitis virus aerosol challenge. J.Exp.Med., 219, 2022
7SGZ	Structure of the yeast Rad24-RFC loader bound to DNA and the closed 9-1-1 clamp 分子名称: ADENOSINE-5'-DIPHOSPHATE, Checkpoint protein RAD24, Crick strand, ... 著者 Zheng, F, Georgescu, R, Yao, Y.N, O'Donnell, M.E, Li, H. 登録日 2021-10-07 公開日 2022-03-23 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.17 Å) 主引用文献 DNA is loaded through the 9-1-1 DNA checkpoint clamp in the opposite direction of the PCNA clamp. Nat.Struct.Mol.Biol., 29, 2022
7SH2	Structure of the yeast Rad24-RFC loader bound to DNA and the open 9-1-1 clamp 分子名称: ADENOSINE-5'-DIPHOSPHATE, Checkpoint protein RAD24, Crick strand, ... 著者 Zheng, F, Georgescu, R, Yao, Y.N, O'Donnell, M.E, Li, H. 登録日 2021-10-07 公開日 2022-03-23 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.23 Å) 主引用文献 DNA is loaded through the 9-1-1 DNA checkpoint clamp in the opposite direction of the PCNA clamp. Nat.Struct.Mol.Biol., 29, 2022
8CFA	HK97 Prohead II as part of a DNA packaging complex 分子名称: Major capsid subunit 著者 Hawkins, D.E.D.P, Antson, A.A. 登録日 2023-02-03 公開日 2023-05-24 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (3.06 Å) 主引用文献 Insights into a viral motor: the structure of the HK97 packaging termination assembly. Nucleic Acids Res., 51, 2023
8CEZ	HK97 Portal Protein In situ (prohead II) 分子名称: Portal protein 著者 Hawkins, D.E.D.P, Antson, A.A. 登録日 2023-02-02 公開日 2023-05-24 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (2.97 Å) 主引用文献 Insights into a viral motor: the structure of the HK97 packaging termination assembly. Nucleic Acids Res., 51, 2023
7SL2	Full-length insulin receptor bound with site 2 binding deficient mutant insulin (A-L13R) -- asymmetric conformation 分子名称: Insulin A chain, Insulin B chain, Insulin receptor 著者 Bai, X.C, Choi, E. 登録日 2021-10-22 公開日 2022-03-30 最終更新日 2022-04-27 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Synergistic activation of the insulin receptor via two distinct sites. Nat.Struct.Mol.Biol., 29, 2022
7SL6	Full-length insulin receptor bound with site 2 binding deficient mutant insulin (B-L17R) -- symmetric conformation 分子名称: Insulin A chain, Insulin B chain, Insulin receptor 著者 Bai, X.C, Choi, E. 登録日 2021-10-22 公開日 2022-03-30 最終更新日 2022-04-27 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Synergistic activation of the insulin receptor via two distinct sites. Nat.Struct.Mol.Biol., 29, 2022
7SL3	Full-length insulin receptor bound with site 2 binding deficient mutant insulin (A-L13R) -- symmetric conformation 分子名称: Insulin A chain, Insulin B chain, Insulin receptor 著者 Bai, X.C, Choi, E. 登録日 2021-10-22 公開日 2022-03-30 最終更新日 2022-04-27 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Synergistic activation of the insulin receptor via two distinct sites. Nat.Struct.Mol.Biol., 29, 2022
7SL4	Full-length insulin receptor bound with site 2 binding deficient mutant insulin (B-L17R) -- asymmetric conformation 分子名称: Insulin A chain, Insulin B chain, Insulin receptor 著者 Bai, X.C, Choi, E. 登録日 2021-10-22 公開日 2022-03-30 最終更新日 2022-04-27 実験手法 ELECTRON MICROSCOPY (5 Å) 主引用文献 Synergistic activation of the insulin receptor via two distinct sites. Nat.Struct.Mol.Biol., 29, 2022
7SL7	Full-length insulin receptor bound with both site 1 binding deficient mutant insulin (A-V3E) and site 2 binding deficient mutant insulin (A-L13R) 分子名称: Insulin A chain (L13R), Insulin A chain (V3E), Insulin B chain, ... 著者 Bai, X.C, Choi, E. 登録日 2021-10-22 公開日 2022-03-30 最終更新日 2024-10-16 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Synergistic activation of the insulin receptor via two distinct sites. Nat.Struct.Mol.Biol., 29, 2022
7SL1	Full-length insulin receptor bound with site 1 binding deficient mutant insulin (A-V3E) 分子名称: Insulin A chain, Insulin B chain, Insulin receptor 著者 Bai, X.C, Choi, E. 登録日 2021-10-22 公開日 2022-03-30 最終更新日 2022-04-27 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Synergistic activation of the insulin receptor via two distinct sites. Nat.Struct.Mol.Biol., 29, 2022
7SHQ	Structure of a functional construct of eukaryotic elongation factor 2 kinase in complex with calmodulin. 分子名称: CALCIUM ION, Calmodulin-1, Eukaryotic elongation factor 2 kinase,Eukaryotic elongation factor 2 kinase, ... 著者 Piserchio, A, Isiorho, E.A, Jeruzalmi, D, Dalby, K.N, Ghose, R. 登録日 2021-10-11 公開日 2022-04-06 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.34 Å) 主引用文献 Structural basis for the calmodulin-mediated activation of eukaryotic elongation factor 2 kinase. Sci Adv, 8, 2022
5MDM	Structural intermediates in the fusion associated transition of vesiculovirus glycoprotein 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Baquero, E, Albertini, A.A, Gaudin, Y, Bressanelli, S. 登録日 2016-11-11 公開日 2016-12-14 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.998 Å) 主引用文献 Structural intermediates in the fusion-associated transition of vesiculovirus glycoprotein. EMBO J., 36, 2017
8IRV	Dopamine Receptor D5R-Gs-Rotigotine complex 分子名称: CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... 著者 Xu, P, Huang, S, Zhuang, Y, Mao, C, Zhang, Y, Wang, Y, Li, H, Jiang, Y, Zhang, Y, Xu, H.E. 登録日 2023-03-19 公開日 2023-06-07 最終更新日 2023-11-08 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural genomics of the human dopamine receptor system. Cell Res., 33, 2023
8IRT	Dopamine Receptor D3R-Gi-Rotigotine complex 分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... 著者 Xu, P, Huang, S, Zhuang, Y, Mao, C, Zhang, Y, Wang, Y, Li, H, Jiang, Y, Zhang, Y, Xu, H.E. 登録日 2023-03-19 公開日 2023-06-07 最終更新日 2023-11-08 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Structural genomics of the human dopamine receptor system. Cell Res., 33, 2023
8IRS	Dopamine Receptor D2R-Gi-Rotigotine complex 分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... 著者 Xu, P, Huang, S, Zhuang, Y, Mao, C, Zhang, Y, Wang, Y, Li, H, Jiang, Y, Zhang, Y, Xu, H.E. 登録日 2023-03-19 公開日 2023-06-07 最終更新日 2023-11-08 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structural genomics of the human dopamine receptor system. Cell Res., 33, 2023
8OH2	Structure of the Tau-PAM4 Type 1 amyloid fibril 分子名称: Microtubule-associated protein tau 著者 Wilkinson, M, Louros, N, Tsaka, G, Ramakers, M, Morelli, C, Garcia, T, Gallardo, R.U, D'Haeyer, S, Goossens, V, Audenaert, D, Thal, D.R, Ranson, N.A, Radford, S.E, Rousseau, F, Schymkowitz, J. 登録日 2023-03-20 公開日 2024-02-21 実験手法 ELECTRON MICROSCOPY (2.6 Å) 主引用文献 Local structural preferences in shaping tau amyloid polymorphism. Nat Commun, 15, 2024
8OIR	55S human mitochondrial ribosome with mtRF1 and P-site tRNA 分子名称: 12S rRNA, 16S rRNA, 28S ribosomal protein S10, ... 著者 Saurer, M, Leibundgut, M, Scaiola, A, Schoenhut, T, Ban, N. 登録日 2023-03-23 公開日 2023-06-14 最終更新日 2024-06-26 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Molecular basis of translation termination at noncanonical stop codons in human mitochondria. Science, 380, 2023
7ZFY	BRD4 in complex with PepLite-Gly 分子名称: 2-acetamido-N-(3-bromanylprop-2-ynyl)ethanamide, Bromodomain-containing protein 4, GLYCEROL 著者 Turberville, S, Martin, M.P, Hope, I, Noble, M.E.M. 登録日 2022-04-01 公開日 2022-11-23 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 Mapping Ligand Interactions of Bromodomains BRD4 and ATAD2 with FragLites and PepLites─Halogenated Probes of Druglike and Peptide-like Molecular Interactions. J.Med.Chem., 65, 2022
7ZKP	Late assembly intermediate of the proximal proton pumping module of complex I with assembly factors NDUFAF1 and CIA84 分子名称: 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CARDIOLIPIN, ... 著者 Schiller, J, Laube, E, Vonck, J, Zickermann, V. 登録日 2022-04-13 公開日 2022-11-23 最終更新日 2022-11-30 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Insights into complex I assembly: Function of NDUFAF1 and a link with cardiolipin remodeling. Sci Adv, 8, 2022
9CEF	Caulobacter crescentus FljN flagellar filament (symmetrized) 分子名称: Flagellin FljN 著者 Sanchez, J.C, Montemayor, E.J, Ploscariu, N.T, Parrell, D, Baumgardt, J.K, Yang, J.E, Sibert, B, Cai, K, Wright, E.R. 登録日 2024-06-26 公開日 2024-08-28 実験手法 ELECTRON MICROSCOPY (2.22 Å) 主引用文献 Direct evidence for multi-flagellin filament stabilization via atomic-level architecture of Caulobacter crescentus flagellar filaments To Be Published
8HQR	Crystal structure of the arginine-/lysine-binding protein SAR11_1210 from 'Candidatus Pelagibacter ubique' HTCC1062 bound to arginine 分子名称: ABC transporter, ARGININE 著者 Clifton, B.E, Laurino, P. 登録日 2022-12-14 公開日 2023-12-27 最終更新日 2024-09-25 実験手法 X-RAY DIFFRACTION (1.32 Å) 主引用文献 The ultra-high affinity transport proteins of ubiquitous marine bacteria. Nature, 2024
9BG1	Tri-complex of Compound-3, KRAS G12V, and CypA 分子名称: (2R)-N-[(1P,7S,9S,13R,20M)-21-ethyl-20-{2-[(1S)-1-methoxyethyl]pyridin-3-yl}-17,17-dimethyl-8,14-dioxo-15-oxa-4-thia-9,21,27,28-tetraazapentacyclo[17.5.2.1~2,5~.1~9,13~.0~22,26~]octacosa-1(24),2,5(28),19,22,25-hexaen-7-yl]-3-methyl-2-(N-methylacetamido)butanamide (non-preferred name), GTPase KRas, MAGNESIUM ION, ... 著者 Tomlinson, A.C.A, Saldajeno-Concar, M, Knox, J.E, Yano, J.K. 登録日 2024-04-18 公開日 2024-06-12 最終更新日 2024-06-26 実験手法 X-RAY DIFFRACTION (1.51 Å) 主引用文献 Tri-complex of Compound-3, KRAS G12V, and CypA To be published

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