PDB: 222624 件ウェブページステータス検索Chemie searchBIRD

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3ERV	Crystal structure of an putative C39-like peptidase from Bacillus anthracis 分子名称: 1,2-ETHANEDIOL, putative C39-like peptidase 著者 Bonanno, J.B, Rutter, M, Bain, K.T, Iizuka, M, Ozyurt, S, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) 登録日 2008-10-03 公開日 2008-10-14 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of an putative C39-like peptidase from Bacillus anthracis To be Published
4HSG	Crystal structure of human PRMT3 in complex with an allosteric inhibitor (PRMT3- KTD) 分子名称: 1-(1,2,3-benzothiadiazol-6-yl)-3-(2-oxo-2-phenylethyl)urea, PRMT3 protein, UNKNOWN ATOM OR ION 著者 Dobrovetsky, E, Dong, A, Liu, F, Li, F, Tempel, W, Siarheyeva, A, Hajian, T, Smil, D, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Schapira, M, Jin, J, Vedadi, M, Structural Genomics Consortium (SGC) 登録日 2012-10-30 公開日 2012-12-05 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Exploiting an allosteric binding site of PRMT3 yields potent and selective inhibitors. J. Med. Chem., 56, 2013
4L9Z	Crystal Structure of Rhodobacter sphaeroides malyl-CoA lyase in complex with magnesium, oxalate, and CoA 分子名称: COENZYME A, MAGNESIUM ION, Malyl-CoA lyase, ... 著者 Zarzycki, J, Kerfeld, C.A. 登録日 2013-06-18 公開日 2013-12-04 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.011 Å) 主引用文献 The crystal structures of the tri-functional Chloroflexus aurantiacus and bi-functional Rhodobacter sphaeroides malyl-CoA lyases and comparison with CitE-like superfamily enzymes and malate synthases. Bmc Struct.Biol., 13, 2013
4HVL	Structure of a serine protease MycP1, an essential component of the type VII (ESX-1) secretion system 分子名称: ACETATE ION, CHLORIDE ION, IMIDAZOLE, ... 著者 Korotkov, K.V, Evans, T.J. 登録日 2012-11-06 公開日 2013-05-08 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Understanding specificity of the mycosin proteases in ESX/type VII secretion by structural and functional analysis. J.Struct.Biol., 184, 2013
4LAU	Crystal structure of human AR complexed with NADP+ and {2-[(4-bromobenzyl)carbamoyl]-5-chlorophenoxy}acetic acid 分子名称: Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, {2-[(4-bromobenzyl)carbamoyl]-5-chlorophenoxy}acetic acid 著者 Cousido-Siah, A, Mitschler, A, Ruiz, F.X, Fanfrlik, J, Kolar, M, Hobza, P, Podjarny, A. 登録日 2013-06-20 公開日 2014-04-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (0.843 Å) 主引用文献 Modulation of aldose reductase inhibition by halogen bond tuning. Acs Chem.Biol., 8, 2013
4LB9	X-ray study of human serum albumin complexed with etoposide 分子名称: (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside, MYRISTIC ACID, SERUM ALBUMIN 著者 Wang, Z, Ho, J.X, Ruble, J, Rose, J.P, Carter, D.C. 登録日 2013-06-20 公開日 2013-07-24 最終更新日 2014-02-19 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural studies of several clinically important oncology drugs in complex with human serum albumin. Biochim.Biophys.Acta, 1830, 2013
4LBR	Crystal structure of human AR complexed with NADP+ and {5-chloro-2-[(2,6-difluoro-4-iodobenzyl)carbamoyl]phenoxy}acetic acid 分子名称: Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, {5-chloro-2-[(2,6-difluoro-4-iodobenzyl)carbamoyl]phenoxy}acetic acid 著者 Cousido-Siah, A, Mitschler, A, Ruiz, F.X, Fanfrlik, J, Kolar, M, Hobza, P, Podjarny, A. 登録日 2013-06-21 公開日 2014-04-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (0.8 Å) 主引用文献 Modulation of aldose reductase inhibition by halogen bond tuning. Acs Chem.Biol., 8, 2013
3NUV	Crystal structure of ketosteroid isomerase D38ND99N from Pseudomonas testosteroni (tKSI) with 4-Androstene-3,17-dione Bound 分子名称: 4-ANDROSTENE-3-17-DIONE, SULFATE ION, Steroid Delta-isomerase 著者 Gonzalez, A, Tsai, Y, Schwans, J, Sunden, F, Herschlag, D. 登録日 2010-07-07 公開日 2011-11-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 Crystal Structure of Ketosteroid Isomerase D38ND99N from Pseudomonas testosteroni (tKSI) with 4-Androstene-3,17-dione Bound TO BE PUBLISHED
4HWO	Crystal structure of E. coli Threonyl-tRNA synthetase bound to a novel inhibitor 分子名称: N-{[3-(4-aminoquinazolin-7-yl)phenyl]sulfonyl}-L-threoninamide, Threonine--tRNA ligase, ZINC ION 著者 Hilgers, M.T. 登録日 2012-11-08 公開日 2013-09-18 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.907 Å) 主引用文献 Identification of bacteria-selective threonyl-tRNA synthetase substrate inhibitors by structure-based design. J.Med.Chem., 56, 2013
3EV3	Crystal Structure of Ribonuclease A in 70% t-Butanol 分子名称: Ribonuclease pancreatic, TERTIARY-BUTYL ALCOHOL 著者 Dechene, M, Wink, G, Smith, M, Swartz, P, Mattos, C. 登録日 2008-10-12 公開日 2009-06-23 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 Multiple solvent crystal structures of ribonuclease A: An assessment of the method Proteins, 76, 2009
3EVR	Crystal structure of Calcium bound monomeric GCAMP2 分子名称: CALCIUM ION, Myosin light chain kinase, Green fluorescent protein, ... 著者 Wang, Q, Shui, B, Kotlikoff, M.I, Sondermann, H. 登録日 2008-10-13 公開日 2008-12-09 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural Basis for Calcium Sensing by GCaMP2. Structure, 16, 2008
4L87	Crystal structure of the human seryl-tRNA synthetase in complex with Ser-SA at 2.9 Angstrom resolution 分子名称: 5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE, MAGNESIUM ION, PHOSPHATE ION, ... 著者 Xu, X, Yang, X.-L. 登録日 2013-06-16 公開日 2013-10-02 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.897 Å) 主引用文献 Crystal Structure of Human Seryl-tRNA Synthetase and Ser-SA Complex Reveals a Molecular Lever Specific to Higher Eukaryotes. Structure, 21, 2013
4L8I	Crystal structure of RSV epitope scaffold FFL_005 分子名称: RSV epitope scaffold FFL_005 著者 Jardine, J, Correnti, C, Holmes, M.A, Strong, R.K, Schief, W.R. 登録日 2013-06-17 公開日 2014-02-12 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Proof of principle for epitope-focused vaccine design. Nature, 507, 2014
3E2R	Crystal Structure PutA86-630 Mutant Y540S Complexed with L-tetrahydro-2-furoic acid 分子名称: CITRIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, PENTAETHYLENE GLYCOL, ... 著者 Tanner, J.J. 登録日 2008-08-06 公開日 2009-02-03 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 A conserved active site tyrosine residue of proline dehydrogenase helps enforce the preference for proline over hydroxyproline as the substrate. Biochemistry, 48, 2009
3NS6	Crystal structure of hte RNA recognition motif of yeast eIF3b residues 76-170 分子名称: Eukaryotic translation initiation factor 3 subunit B, SULFATE ION 著者 Khoshnevis, S, Neumann, P, Ficner, R. 登録日 2010-07-01 公開日 2010-10-06 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Crystal structure of the RNA recognition motif of yeast translation initiation factor eIF3b reveals differences to human eIF3b. Plos One, 5, 2010
4L71	Crystal Structure of Frameshift Suppressor tRNA SufA6 Bound to Codon CCC-A on the Ribosome 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... 著者 Maehigashi, T, Dunkle, J.A, Dunham, C.M. 登録日 2013-06-13 公開日 2014-08-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.900001 Å) 主引用文献 Structural insights into +1 frameshifting promoted by expanded or modification-deficient anticodon stem loops. Proc.Natl.Acad.Sci.USA, 111, 2014
4L9I	Bovine G Protein Coupled Receptor Kinase 1 in Complex with Paroxetine 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, Paroxetine, ... 著者 Homan, K.T, Tesmer, J.J.G. 登録日 2013-06-18 公開日 2014-01-22 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.32 Å) 主引用文献 Structural and functional analysis of g protein-coupled receptor kinase inhibition by paroxetine and a rationally designed analog. Mol.Pharmacol., 85, 2014
4LAZ	Crystal structure of human AR complexed with NADP+ and {5-chloro-2-[(4-iodobenzyl)carbamoyl]phenoxy}acetic acid 分子名称: Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, {5-chloro-2-[(4-iodobenzyl)carbamoyl]phenoxy}acetic acid 著者 Cousido-Siah, A, Mitschler, A, Ruiz, F.X, Fanfrlik, J, Kolar, M, Hobza, P, Podjarny, A. 登録日 2013-06-20 公開日 2014-04-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (0.85 Å) 主引用文献 Modulation of aldose reductase inhibition by halogen bond tuning. Acs Chem.Biol., 8, 2013
3EGY	Crystal Structure of Human Thymidyalte Synthase A191K with Loop 181-197 stabilized in the inactive conformation 分子名称: 1,2-ETHANEDIOL, SULFATE ION, Thymidylate synthase 著者 Lovelace, L.L, Gibson, L.M, Johnson, S.R, Berger, S.H, Lebioda, L. 登録日 2008-09-11 公開日 2009-08-18 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.18 Å) 主引用文献 Variants of human thymidylate synthase with loop 181-197 stabilized in the inactive conformation. Protein Sci., 18, 2009
2IO2	Crystal structure of human Senp2 in complex with RanGAP1-SUMO-1 分子名称: Ran GTPase-activating protein 1, Sentrin-specific protease 2, Small ubiquitin-related modifier 1 著者 Reverter, D, Lima, C.D. 登録日 2006-10-09 公開日 2006-11-21 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural basis for SENP2 protease interactions with SUMO precursors and conjugated substrates. Nat.Struct.Mol.Biol., 13, 2006
4HVV	Crystal structure of the T98E c-Src-SH3 domain mutant in complex with the high affinity peptide APP12 分子名称: Proto-oncogene tyrosine-protein kinase Src, SULFATE ION, SYNTHETIC PEPTIDE Acetyl-APPLPPRNRP 著者 Camara-Artigas, A. 登録日 2012-11-07 公開日 2013-05-01 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 Atomic resolution structures of the c-Src SH3 domain in complex with two high-affinity peptides from classes I and II. Acta Crystallogr.,Sect.D, 69, 2013
3EI3	Structure of the hsDDB1-drDDB2 complex 分子名称: DNA damage-binding protein 1, DNA damage-binding protein 2, TETRAETHYLENE GLYCOL 著者 Scrima, A, Thoma, N.H. 登録日 2008-09-15 公開日 2009-01-20 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis of UV DNA-damage recognition by the DDB1-DDB2 complex. Cell(Cambridge,Mass.), 135, 2008
3O16	Crystal Structure of Bacillus subtilis Thiamin Phosphate Synthase K159A 分子名称: Thiamine-phosphate pyrophosphorylase 著者 McCulloch, K.M, Hanes, J.W, Abdelwahed, S, Mahanta, N, Hazra, A, Ishida, K, Begley, T.P, Ealick, S.E. 登録日 2010-07-20 公開日 2011-07-27 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal Structure and Kinetic Characterization of Bacillus subtilis Thiamin Phosphate Synthase with a Carboxylated Thiazole Phosphate to be published
4I3W	Structure of phosphonoacetaldehyde dehydrogenase in complex with gylceraldehyde-3-phosphate and cofactor NAD+ 分子名称: Aldehyde dehydrogenase (NAD+), GLYCERALDEHYDE-3-PHOSPHATE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Nair, S.K, Agarwal, V. 登録日 2012-11-26 公開日 2013-11-27 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (2.24 Å) 主引用文献 Structure and function of phosphonoacetaldehyde dehydrogenase: the missing link in phosphonoacetate formation. Chem.Biol., 21, 2014
3NXZ	Crystal Structure of UreE from Helicobacter pylori (Cu2+ bound form) 分子名称: COPPER (II) ION, Urease accessory protein ureE 著者 Shi, R, Munger, C, Assinas, A, Matte, A, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) 登録日 2010-07-14 公開日 2010-08-25 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal Structures of Apo and Metal-Bound Forms of the UreE Protein from Helicobacter pylori: Role of Multiple Metal Binding Sites Biochemistry, 49, 2010

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