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5IRC
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BU of 5irc by Molmil
p190A GAP domain complex with RhoA
分子名称: CHLORIDE ION, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Derewenda, U, Derewenda, Z.
登録日2016-03-12
公開日2016-08-17
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Deciphering the Molecular and Functional Basis of RHOGAP Family Proteins: A SYSTEMATIC APPROACH TOWARD SELECTIVE INACTIVATION OF RHO FAMILY PROTEINS.
J.Biol.Chem., 291, 2016
3MFK
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BU of 3mfk by Molmil
Ets1 complex with stromelysin-1 promoter DNA
分子名称: Protein C-ets-1, stromelysin-1 promoter DNA
著者Babayeva, N.D, Mino, K, Tahirov, T.H.
登録日2010-04-02
公開日2010-08-18
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis of Ets1 cooperative binding to palindromic sequences on stromelysin-1 promoter DNA.
Cell Cycle, 9, 2010
1DL6
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BU of 1dl6 by Molmil
SOLUTION STRUCTURE OF HUMAN TFIIB N-TERMINAL DOMAIN
分子名称: TRANSCRIPTION FACTOR II B (TFIIB), ZINC ION
著者Chen, H.-T, Legault, P, Glushka, J, Omichinski, J.G, Scott, R.A.
登録日1999-12-08
公開日2000-10-18
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure of a (Cys3His) zinc ribbon, a ubiquitous motif in archaeal and eucaryal transcription.
Protein Sci., 9, 2000
3R63
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BU of 3r63 by Molmil
Structure of ERK2 (SPE) mutant (S246E)
分子名称: Mitogen-activated protein kinase 1
著者Livnah, O, Karamansha, Y.
登録日2011-03-21
公開日2011-08-17
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Nuclear ERK translocation is mediated by protein kinase CK2 and accelerated by autophosphorylation.
Mol.Cell.Biol., 31, 2011
2VRI
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BU of 2vri by Molmil
Structure of the NSP3 X-domain of human coronavirus NL63
分子名称: 1,2-ETHANEDIOL, NON-STRUCTURAL PROTEIN 3
著者Piotrowski, Y, Mesters, J.R, Moll, R, Hilgenfeld, R.
登録日2008-04-08
公開日2009-06-09
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of the Nsp3 X-Domain of Human Coronavirus Nl63
To be Published
1JN7
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BU of 1jn7 by Molmil
Solution Structure of a CCHH mutant of the ninth CCHC Zinc Finger of U-shaped
分子名称: U-shaped TRANSCRIPTIONAL COFACTOR, ZINC ION
著者Kowalski, K, Mackay, J.P.
登録日2001-07-23
公開日2002-09-25
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Characterization of the Conserved Interaction between GATA and FOG Family Proteins
J.Biol.Chem., 277, 2002
1HXS
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BU of 1hxs by Molmil
CRYSTAL STRUCTURE OF MAHONEY STRAIN OF POLIOVIRUS AT 2.2A RESOLUTION
分子名称: GENOME POLYPROTEIN, COAT PROTEIN VP1, COAT PROTEIN VP2, ...
著者Miller, S.T, Hogle, J.M, Filman, D.J.
登録日2001-01-16
公開日2002-01-16
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Ab initio phasing of high-symmetry macromolecular complexes: successful phasing of authentic poliovirus data to 3.0 A resolution.
J.Mol.Biol., 307, 2001
3SA0
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BU of 3sa0 by Molmil
Complex of ERK2 with norathyriol
分子名称: Mitogen-activated protein kinase 1, SULFATE ION, norathyriol
著者Kurinov, I, Malakhova, M.
登録日2011-06-02
公開日2011-12-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.5947 Å)
主引用文献Norathyriol Suppresses Skin Cancers Induced by Solar Ultraviolet Radiation by Targeting ERK Kinases.
Cancer Res., 72, 2012
1ENW
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BU of 1enw by Molmil
ELONGATION FACTOR TFIIS DOMAIN II
分子名称: TRANSCRIPTION ELONGATION FACTOR S-II
著者Morin, P.E, Awrey, D.E, Edwards, A.M, Arrowsmith, C.H.
登録日2000-03-21
公開日2000-04-12
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Elongation factor TFIIS contains three structural domains: solution structure of domain II.
Proc.Natl.Acad.Sci.USA, 93, 1996
1PDV
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BU of 1pdv by Molmil
Crystal structure of human DJ-1, P 31 2 1 space group
分子名称: DJ-1
著者Tao, X, Tong, L.
登録日2003-05-20
公開日2003-06-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure of Human DJ-1, a Protein Associated with Early Onset Parkinson's Disease.
J.Biol.Chem., 278, 2003
1PDW
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BU of 1pdw by Molmil
Crystal structure of human DJ-1, P 1 21 1 space group
分子名称: DJ-1
著者Tao, X, Tong, L.
登録日2003-05-20
公開日2003-06-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structure of Human DJ-1, a Protein Associated with Early Onset Parkinson's Disease.
J.Biol.Chem., 278, 2003
1HIK
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BU of 1hik by Molmil
INTERLEUKIN-4 (WILD-TYPE)
分子名称: INTERLEUKIN-4
著者Mueller, T, Buehner, M.
登録日1995-06-01
公開日1996-01-29
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Human interleukin-4 and variant R88Q: phasing X-ray diffraction data by molecular replacement using X-ray and nuclear magnetic resonance models.
J.Mol.Biol., 247, 1995
1KO9
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BU of 1ko9 by Molmil
Native Structure of the Human 8-oxoguanine DNA Glycosylase hOGG1
分子名称: 8-oxoguanine DNA glycosylase, SULFATE ION
著者Bjoras, M, Seeberg, E, Luna, L, Pearl, L.H, Barrett, T.E.
登録日2001-12-20
公開日2002-01-09
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Reciprocal "flipping" underlies substrate recognition and catalytic activation by the human 8-oxo-guanine DNA glycosylase.
J.Mol.Biol., 317, 2002
2OR3
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BU of 2or3 by Molmil
Pre-oxidation Complex of Human DJ-1
分子名称: Protein DJ-1, SULFATE ION
著者Witt, A.C, Lakshminarasimhan, M, Wilson, M.A.
登録日2007-02-01
公開日2007-02-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Cysteine pKa depression by a protonated glutamic acid in human DJ-1.
Biochemistry, 47, 2008
2FIX
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BU of 2fix by Molmil
Structure of human liver FBPase complexed with potent benzoxazole allosteric inhibitiors
分子名称: Fructose-1,6-bisphosphatase 1, N-[7-(3-AMINOPHENYL)-5-METHOXY-1,3-BENZOXAZOL-2-YL]-2,5-DICHLOROBENZENESULFONAMIDE
著者Abad-Zapatero, C.
登録日2005-12-30
公開日2006-02-21
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Benzoxazole benzenesulfonamides as allosteric inhibitors of fructose-1,6-bisphosphatase.
Bioorg.Med.Chem.Lett., 16, 2006
4JCJ
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BU of 4jcj by Molmil
Crystal structure of Isl1 LIM domains with Ldb1 LIM-interaction domain
分子名称: Insulin gene enhancer protein ISL-1,LIM domain-binding protein 1, ZINC ION
著者Gadd, M.S, Jacques, D.A, Guss, J.M, Matthews, J.M.
登録日2013-02-21
公開日2013-06-19
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A structural basis for the regulation of the LIM-homeodomain protein islet 1 (Isl1) by intra- and intermolecular interactions.
J.Biol.Chem., 288, 2013
4KRD
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BU of 4krd by Molmil
Crystal Structure of Pho85-Pcl10 Complex
分子名称: Cyclin-dependent protein kinase PHO85, PHO85 cyclin-10
著者Quiocho, F.A, Zheng, F.
登録日2013-05-16
公開日2013-09-18
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.952 Å)
主引用文献New Structural Insights into Phosphorylation-free Mechanism for Full Cyclin-dependent Kinase (CDK)-Cyclin Activity and Substrate Recognition.
J.Biol.Chem., 288, 2013
4ARZ
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BU of 4arz by Molmil
The crystal structure of Gtr1p-Gtr2p complexed with GTP-GDP
分子名称: GTP-BINDING PROTEIN GTR1, GTP-BINDING PROTEIN GTR2, GUANOSINE-5'-DIPHOSPHATE, ...
著者Jeong, J.H, Kim, Y.G.
登録日2012-04-27
公開日2012-07-25
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal Structure of the Gtr1Pgtp-Gtr2Pgdp Complex Reveals Large Structural Rearrangements Triggered by GTP-to-Gdp Conversion
J.Biol.Chem., 287, 2012
2G99
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BU of 2g99 by Molmil
Structural basis for the specific recognition of methylated histone H3 lysine 4 by the WD-40 protein WDR5
分子名称: Histone H3, WD-repeat protein 5
著者Chai, J, Han, Z, Wang, H, Shen, Y.
登録日2006-03-06
公開日2006-09-06
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for the specific recognition of methylated histone H3 lysine 4 by the WD-40 protein WDR5
To be published
7N7I
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BU of 7n7i by Molmil
X-ray crystal structure of Viperin-like enzyme from Trichoderma virens
分子名称: IRON/SULFUR CLUSTER, S-ADENOSYLMETHIONINE, URIDINE 5'-TRIPHOSPHATE, ...
著者Grove, T.L, Almo, S.C, Bonanno, J.B, Lachowicz, J.C, Gizzi, A.G.
登録日2021-06-10
公開日2021-06-30
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.19 Å)
主引用文献Structural Insight into the Substrate Scope of Viperin and Viperin-like Enzymes from Three Domains of Life.
Biochemistry, 60, 2021
4B9K
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BU of 4b9k by Molmil
pVHL-ELOB-ELOC complex_(2S,4R)-1-(3-amino-2-methylbenzoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide bound
分子名称: (2S,4R)-1-(3-amino-2-methylbenzoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide, ACETATE ION, TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 1, ...
著者Buckley, D.L, Gustafson, J.L, VanMolle, I, Roth, A.G, SeopTae, H, Gareiss, P.C, Jorgensen, W.L, Ciulli, A, Crews, C.M.
登録日2012-09-05
公開日2012-10-24
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Small-Molecule Inhibitors of the Interaction between the E3 Ligase Vhl and Hif1 Alpha
Angew.Chem.Int.Ed.Engl., 51, 2012
4G3V
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BU of 4g3v by Molmil
Crystal structure of A. Aeolicus nlh2 gaf domain in an inactive state
分子名称: CHLORIDE ION, Transcriptional regulator nlh2
著者Batchelor, J.D, Lee, P, Wang, A, Doucleff, M, Wemmer, D.E.
登録日2012-07-15
公開日2013-05-29
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural mechanism of GAF-regulated delta(54) activators from Aquifex aeolicus
J.Mol.Biol., 425, 2013
7N7H
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BU of 7n7h by Molmil
X-ray crystal structure of Viperin-like enzyme from Nematostella vectensis
分子名称: CYTIDINE-5'-TRIPHOSPHATE, IRON/SULFUR CLUSTER, S-ADENOSYLMETHIONINE, ...
著者Grove, T.L, Almo, S.C, Bonanno, J.B, Lachowicz, J.C, Gizzi, A.G.
登録日2021-06-10
公開日2021-07-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献Structural Insight into the Substrate Scope of Viperin and Viperin-like Enzymes from Three Domains of Life.
Biochemistry, 60, 2021
4CRL
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BU of 4crl by Molmil
Crystal structure of human CDK8-Cyclin C in complex with cortistatin A
分子名称: CORTISTATIN A, CYCLIN-C, CYCLIN-DEPENDENT KINASE 8, ...
著者Myers, A.G, Shair, M.D.
登録日2014-02-27
公開日2015-09-23
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Mediator Kinase Inhibition Further Activates Super-Enhancer- Associated Genes in Aml
Nature, 526, 2015
8CE7
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BU of 8ce7 by Molmil
Type1 alpha-synuclein filament assembled in vitro by wild-type and mutant (7 residues insertion) protein
分子名称: Alpha-synuclein
著者Yang, Y, Garringer, J.H, Shi, Y, Lovestam, S, Peak-Chew, S.Y, Zhang, X.J, Kotecha, A, Bacioglu, M, Koto, A, Takao, M, Spillantini, G.M, Ghetti, B, Vidal, R, Murzin, G.A, Scheres, H.W.S, Goedert, M.
登録日2023-02-01
公開日2023-03-01
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献New SNCA mutation and structures of alpha-synuclein filaments from juvenile-onset synucleinopathy.
Acta Neuropathol, 145, 2023

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