3PZF
| 1.75A resolution structure of Serpin-2 from Anopheles gambiae | 分子名称: | Serpin 2 | 著者 | Lovell, S, Battaile, K.P, An, C, Michel, K. | 登録日 | 2010-12-14 | 公開日 | 2011-02-16 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Crystal structure of native Anopheles gambiae serpin-2, a negative regulator of melanization in mosquitoes. Proteins, 79, 2011
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4GBD
| Crystal Structure Of Adenosine Deaminase From Pseudomonas Aeruginosa Pao1 with bound Zn and methylthio-coformycin | 分子名称: | (8R)-3-(5-S-methyl-5-thio-beta-D-ribofuranosyl)-3,6,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol, PHOSPHATE ION, Putative uncharacterized protein, ... | 著者 | Ho, M, Guan, R, Almo, S.C, Schramm, V.L. | 登録日 | 2012-07-27 | 公開日 | 2013-06-12 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.975 Å) | 主引用文献 | Methylthioadenosine deaminase in an alternative quorum sensing pathway in Pseudomonas aeruginosa. Biochemistry, 51, 2012
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2RJR
| Substrate mimic bound to SgTAM | 分子名称: | (2S,3S)-3-(4-fluorophenyl)-2,3-dihydroxypropanoic acid, Tyrosine aminomutase | 著者 | Montavon, T.J, Christianson, C.V, Bruner, S.D. | 登録日 | 2007-10-15 | 公開日 | 2008-01-15 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Design and characterization of mechanism-based inhibitors for the tyrosine aminomutase SgTAM. Bioorg.Med.Chem.Lett., 18, 2008
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4G2W
| Crystal structure of PDE5A in complex with its inhibitor | 分子名称: | 5,6-diethyl-2-{5-[(4-methylpiperazin-1-yl)sulfonyl]-2-propoxyphenyl}pyrimidin-4(3H)-one, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ... | 著者 | Ren, J, Chen, T.T, Xu, Y.C. | 登録日 | 2012-07-13 | 公開日 | 2013-06-26 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | Design, synthesis, and pharmacological evaluation of monocyclic pyrimidinones as novel inhibitors of PDE5. J.Med.Chem., 55, 2012
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3Q2A
| Toluene 4 monooxygenase HD complex with inhibitor p-aminobenzoate | 分子名称: | 2-{2-[2-2-(METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 4-AMINOBENZOIC ACID, FE (III) ION, ... | 著者 | Acheson, J.F, Bailey, L.J, Fox, B.G. | 登録日 | 2010-12-19 | 公開日 | 2011-12-21 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Crystallographic analysis of active site contributions to regiospecificity in the diiron enzyme toluene 4-monooxygenase. Biochemistry, 51, 2012
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2RKY
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2RL8
| Crystal Structure cation-dependent mannose 6-phosphate receptor at pH 6.5 bound to M6P | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 6-O-phosphono-beta-D-mannopyranose, Cation-dependent mannose-6-phosphate receptor, ... | 著者 | Olson, L.J, Hindsgaul, O, Kim, J.-J.P, Dahms, N.M. | 登録日 | 2007-10-18 | 公開日 | 2008-02-12 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Structural Insights into the Mechanism of pH-dependent Ligand Binding and Release by the Cation-dependent Mannose 6-Phosphate Receptor. J.Biol.Chem., 283, 2008
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3Q3O
| Toluene 4 monooxygenase HD complex with phenol | 分子名称: | FE (III) ION, PENTAETHYLENE GLYCOL, PHENOL, ... | 著者 | Acheson, J.F, Bailey, L.J, Fox, B.G. | 登録日 | 2010-12-22 | 公開日 | 2011-12-28 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Crystallographic analysis of active site contributions to regiospecificity in the diiron enzyme toluene 4-monooxygenase. Biochemistry, 51, 2012
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4GDA
| Circular Permuted Streptavidin A50/N49 | 分子名称: | BIOTIN, ETHANOL, GLYCEROL, ... | 著者 | Le Trong, I, Chu, V, Xing, Y, Lybrand, T.P, Stayton, P.S, Stenkamp, R.E. | 登録日 | 2012-07-31 | 公開日 | 2013-06-05 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1 Å) | 主引用文献 | Structural consequences of cutting a binding loop: two circularly permuted variants of streptavidin. Acta Crystallogr.,Sect.D, 69, 2013
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4G5J
| Crystal structure of EGFR kinase in complex with BIBW2992 | 分子名称: | (2E)-N-{4-[(3-chloro-4-fluorophenyl)amino]-7-[(3S)-tetrahydrofuran-3-yloxy]quinazolin-6-yl}-4-(dimethylamino)but-2-enamide, Epidermal growth factor receptor, N-{4-[(3-chloro-4-fluorophenyl)amino]-7-[(3S)-tetrahydrofuran-3-yloxy]quinazolin-6-yl}-4-(dimethylamino)butanamide | 著者 | Solca, F, Dahl, G, Zoephel, A, Bader, G, Sanderson, M, Klein, C, Kraemer, O, Himmelsbach, F, Haaksma, E, Adolf, G.R. | 登録日 | 2012-07-18 | 公開日 | 2012-08-29 | 最終更新日 | 2012-10-31 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Target Binding Properties and Cellular Activity of Afatinib (BIBW 2992), an Irreversible ErbB Family Blocker. J.Pharmacol.Exp.Ther., 343, 2012
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3PRA
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3PHZ
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4GF0
| Crystal structure of glutahtione transferase homolog from sulfitobacter, TARGET EFI-501084, with bound glutathione | 分子名称: | CHLORIDE ION, GLUTATHIONE, Glutathione S-transferase | 著者 | Vetting, M.W, Toro, R, Bhosle, R, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Armstrong, R.N, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | 登録日 | 2012-08-02 | 公開日 | 2012-08-29 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Crystal structure of glutahtione transferase homolog from sulfitobacter, TARGET EFI-501084, with bound glutathione To be Published
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4G84
| Crystal structure of human HisRS | 分子名称: | CHLORIDE ION, Histidine--tRNA ligase, cytoplasmic, ... | 著者 | Wei, Z, Wu, J, Zhou, J.J, Yang, X.-L, Zhang, M, Schimmel, P. | 登録日 | 2012-07-21 | 公開日 | 2012-09-26 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Internally Deleted Human tRNA Synthetase Suggests Evolutionary Pressure for Repurposing. Structure, 20, 2012
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3PKQ
| Q83D Variant of S. Enterica RmlA with dGTP | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DI(HYDROXYETHYL)ETHER, Glucose-1-phosphate thymidylyltransferase, ... | 著者 | Chang, A, Moretti, R, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) | 登録日 | 2010-11-11 | 公開日 | 2011-01-12 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Expanding the Nucleotide and Sugar 1-Phosphate Promiscuity of Nucleotidyltransferase RmlA via Directed Evolution. J.Biol.Chem., 286, 2011
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4G8R
| Crystal Structure of a novel small molecule inactivator bound to plasminogen activator inhibitor-1 | 分子名称: | (2S)-3-({[3-(trifluoromethyl)phenoxy]carbonyl}amino)propane-1,2-diyl bis(3,4,5-trihydroxybenzoate), Plasminogen activator inhibitor-1, SULFATE ION | 著者 | Stuckey, J.A, Lawrence, D.A, Li, S.-H. | 登録日 | 2012-07-23 | 公開日 | 2013-12-25 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | 主引用文献 | Mechanistic characterization and crystal structure of a small molecule inactivator bound to plasminogen activator inhibitor-1. Proc.Natl.Acad.Sci.USA, 110, 2013
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3PTW
| CRYSTAL STRUCTURE OF malonyl CoA-acyl carrier protein transacylase from Clostridium perfringens Atcc 13124 | 分子名称: | Malonyl CoA-acyl carrier protein transacylase | 著者 | Malashkevich, V.N, Toro, R, Ramagopal, U, Seidel, R, Foti, R, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) | 登録日 | 2010-12-03 | 公開日 | 2010-12-15 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | CRYSTAL STRUCTURE OF malonyl CoA-acyl carrier protein transacylase from Clostridium perfringens
Atcc 13124 To be Published
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4G9H
| Crystal structure of glutahtione s-transferase homolog from yersinia pestis, target EFI-501894, with bound glutathione | 分子名称: | GLUTATHIONE, GLYCEROL, Glutathione S-transferase | 著者 | Vetting, M.W, Toro, R, Bhosle, R, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Armstrong, R.N, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | 登録日 | 2012-07-23 | 公開日 | 2012-08-15 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structure of glutahtione s-transferase homolog from yersinia pestis, target efi-501894, with bound glutathione To be Published
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4GI0
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3PI2
| Crystallographic Structure of HbII-oxy from Lucina pectinata at pH 8.0 | 分子名称: | FORMIC ACID, Hemoglobin II, OXYGEN MOLECULE, ... | 著者 | Gavira, J.A, Nieves-Marrero, C.A, Ruiz-Martinez, C.R, Estremera-Andujar, R.A, Lopez-Garriga, J, Garcia-Ruiz, J.M. | 登録日 | 2010-11-05 | 公開日 | 2011-11-09 | 最終更新日 | 2016-12-21 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | pH-dependence crystallographic studies of the oxygen carrier hemoglobin II from Lucina pectinata To be Published
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4GKP
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2FTS
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4FSJ
| Crystal structure of the virus like particle of Flock House virus | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ... | 著者 | Speir, J.A, Chen, Z, Reddy, V.S, Johnson, J.E. | 登録日 | 2012-06-27 | 公開日 | 2012-08-01 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Structural study of virus assembly intermediates reveals maturation event sequence and a staging position for externalized lytic peptides to be published, 2012
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4GM0
| Crystal Structure of Benzoylformate Decarboxylase Mutant L403N | 分子名称: | 2-{3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-4-METHYL-2-OXO-2,3-DIHYDRO-1,3-THIAZOL-5-YL}ETHYL TRIHYDROGEN DIPHOSPHATE, Benzoylformate decarboxylase, CALCIUM ION, ... | 著者 | Novak, W.R.P, Andrews, F.H, Tom, A.R, Gunderman, P.R, McLeish, M.J. | 登録日 | 2012-08-15 | 公開日 | 2013-05-22 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.07 Å) | 主引用文献 | A bulky hydrophobic residue is not required to maintain the v-conformation of enzyme-bound thiamin diphosphate. Biochemistry, 52, 2013
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2FWO
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