8H3Z
 
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6SST
 | | cryo-em structure of alpha-synuclein fibril polymorph 2B | | 分子名称: | Alpha-synuclein | | 著者 | Guerrero-Ferreira, R, Taylor, N.M.I, Arteni, A.A, Melki, R, Meier, B.H, Bockmann, A, Bousset, L, Stahlberg, H. | | 登録日 | 2019-09-09 | | 公開日 | 2019-12-18 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Two new polymorphic structures of human full-length alpha-synuclein fibrils solved by cryo-electron microscopy.
Elife, 8, 2019
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2XHI
 | | Separation-of-function mutants unravel the dual reaction mode of human 8-oxoguanine DNA glycosylase | | 分子名称: | 5'-D(*GP*CP*GP*TP*CP*CP*AP*(8OG)P*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', CALCIUM ION, ... | | 著者 | Dalhus, B, Forsbring, M, Helle, I.H, Backe, P.H, Forstrom, R.J, Alseth, I, Bjoras, M. | | 登録日 | 2010-06-16 | | 公開日 | 2011-01-26 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Separation-of-Function Mutants Unravel the Dual- Reaction Mode of Human 8-Oxoguanine DNA Glycosylase.
Structure, 19, 2011
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2XL2
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6SSX
 | | cryo-em structure of alpha-synuclein fibril polymorph 2A | | 分子名称: | Alpha-synuclein | | 著者 | Guerrero-Ferreira, R, Taylor, N.M.I, Arteni, A.A, Melki, R, Meier, B.H, Bockmann, A, Bousset, L, Stahlberg, H. | | 登録日 | 2019-09-09 | | 公開日 | 2019-12-18 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (2.98 Å) | | 主引用文献 | Two new polymorphic structures of human full-length alpha-synuclein fibrils solved by cryo-electron microscopy.
Elife, 8, 2019
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6YJL
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1CQG
 | | HIGH RESOLUTION SOLUTION NMR STRUCTURE OF MIXED DISULFIDE INTERMEDIATE BETWEEN HUMAN THIOREDOXIN (C35A, C62A, C69A, C73A) MUTANT AND A 13 RESIDUE PEPTIDE COMPRISING ITS TARGET SITE IN HUMAN REF-1 (RESIDUES 59-71 OF THE P50 SUBUNIT OF NFKB), NMR, 31 STRUCTURES | | 分子名称: | REF-1 PEPTIDE, THIOREDOXIN | | 著者 | Clore, G.M, Qin, J, Gronenborn, A.M. | | 登録日 | 1996-04-02 | | 公開日 | 1996-08-01 | | 最終更新日 | 2021-11-03 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The solution structure of human thioredoxin complexed with its target from Ref-1 reveals peptide chain reversal.
Structure, 4, 1996
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4HC7
 | | Crystal structure of the full DNA binding domain of GATA3-complex 2 | | 分子名称: | DNA (5'-D(*AP*AP*GP*GP*TP*TP*AP*TP*CP*TP*CP*TP*GP*AP*TP*TP*TP*AP*GP*G)-3'), DNA (5'-D(*TP*TP*CP*CP*TP*AP*AP*AP*TP*CP*AP*GP*AP*GP*AP*TP*AP*AP*CP*C)-3'), Trans-acting T-cell-specific transcription factor GATA-3, ... | | 著者 | Chen, Y, Bates, D.L, Dey, R, Chen, L. | | 登録日 | 2012-09-28 | | 公開日 | 2012-12-05 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | DNA Binding by GATA Transcription Factor Suggests Mechanisms of DNA Looping and Long-Range Gene Regulation.
Cell Rep, 2, 2012
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3CFS
 | | Structural basis of the interaction of RbAp46/RbAp48 with histone H4 | | 分子名称: | ARSENIC, Histone H4, Histone-binding protein RBBP7 | | 著者 | Murzina, N.V, Pei, X.-Y, Pratap, J.V, Sparkes, M, Vicente-Garcia, J, Ben-Shahar, T.R, Verreault, A, Luisi, B.F, Laue, E.D. | | 登録日 | 2008-03-04 | | 公開日 | 2008-06-10 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural Basis for the Recognition of Histone H4 by the Histone-Chaperone RbAp46.
Structure, 16, 2008
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2Y5K
 | | Orally active aminopyridines as inhibitors of tetrameric fructose 1,6- bisphosphatase | | 分子名称: | 1-[5-(2-METHOXYETHYL)-4-METHYL-THIOPHEN-2-YL]SULFONYL-3-[4-METHOXY-6-(METHYLCARBAMOYLAMINO)PYRIDIN-2-YL]UREA, FRUCTOSE-1,6-BISPHOSPHATASE 1 | | 著者 | Ruf, A, Hebeisen, P, Haap, W, Kuhn, B, Mohr, P, Wessel, H.P, Zutter, U, Kirchner, S, Benz, J, Joseph, C, Alvarez-Sanchez, R, Gubler, M, Schott, B, Benardeau, A, Tozzo, E, Kitas, E. | | 登録日 | 2011-01-14 | | 公開日 | 2011-05-18 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Orally Active Aminopyridines as Inhibitors of Tetrameric Fructose-1,6-Bisphosphatase.
Bioorg.Med.Chem.Lett., 21, 2011
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6WAG
 | | Crystal Structure of SmcR S76A from Vibrio Vulnificus | | 分子名称: | 1,2-ETHANEDIOL, LuxR family transcriptional regulator, SULFATE ION | | 著者 | Newman, J.D, Russell, M.M, Gonzalez-Gutierrez, G, van Kessel, J.C. | | 登録日 | 2020-03-25 | | 公開日 | 2020-06-17 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.575 Å) | | 主引用文献 | The DNA binding domain of the Vibrio vulnificus SmcR transcription factor is flexible and binds diverse DNA sequences.
Nucleic Acids Res., 49, 2021
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4X51
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6WAF
 | | Crystal Structure of SmcR N55I from Vibrio vulnificus | | 分子名称: | LuxR family transcriptional regulator, SULFATE ION | | 著者 | Newman, J.D, Russell, M.M, Gonzalez-Gutierrez, G, van Kessel, J.C. | | 登録日 | 2020-03-25 | | 公開日 | 2020-06-17 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.381 Å) | | 主引用文献 | The DNA binding domain of the Vibrio vulnificus SmcR transcription factor is flexible and binds diverse DNA sequences.
Nucleic Acids Res., 49, 2021
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6WAH
 | | Crystal Structure of SmcR L139R from Vibrio vulnificus | | 分子名称: | 1,2-ETHANEDIOL, LuxR family transcriptional regulator, SULFATE ION | | 著者 | Newman, J.D, Russell, M.M, Gonzalez-Gutierrez, G, van Kessel, J.C. | | 登録日 | 2020-03-25 | | 公開日 | 2020-06-17 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | The DNA binding domain of the Vibrio vulnificus SmcR transcription factor is flexible and binds diverse DNA sequences.
Nucleic Acids Res., 49, 2021
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2Y5L
 | | orally active aminopyridines as inhibitors of tetrameric fructose 1,6- bisphosphatase | | 分子名称: | FRUCTOSE-1,6-BISPHOSPHATASE 1, N-{[(2Z)-5-bromo-1,3-thiazol-2(3H)-ylidene]carbamoyl}-3-chlorobenzenesulfonamide | | 著者 | ruf, a, hebeisen, p, haap, w, kuhn, b, mohr, p, wessel, h.p, zutter, u, kirchner, s, benz, j, joseph, c, alvarez-sanchez, r, gubler, m, schott, b, benardeau, a, tozzo, e, kitas, e. | | 登録日 | 2011-01-14 | | 公開日 | 2011-05-18 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Orally Active Aminopyridines as Inhibitors of Tetrameric Fructose-1,6-Bisphosphatase.
Bioorg.Med.Chem.Lett., 21, 2011
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2YPB
 | | Structure of the SCL:E47 complex bound to DNA | | 分子名称: | EBOX FORWARD, EBOX REVERSE, T-CELL ACUTE LYMPHOCYTIC LEUKEMIA PROTEIN 1, ... | | 著者 | El Omari, K, Hoosdally, S.J, Tuladhar, K, Karia, D, Ponsele, E, Platonova, O, Vyas, P, Patient, R, Porcher, C, Mancini, E.J. | | 登録日 | 2012-10-30 | | 公開日 | 2013-07-31 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.87 Å) | | 主引用文献 | Structural Basis for Lmo2-Driven Recruitment of the Scl:E47bHLH Heterodimer to Hematopoietic-Specific Transcriptional Targets.
Cell Rep., 4, 2013
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7P35
 | | Structure of the SARS-CoV-2 3CL protease in complex with rupintrivir | | 分子名称: | 3C-like proteinase, 4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER | | 著者 | Fabrega-Ferrer, M, Perez-Saavedra, J, Herrera-Morande, A, Coll, M. | | 登録日 | 2021-07-07 | | 公開日 | 2021-07-21 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.256 Å) | | 主引用文献 | Structure and inhibition of SARS-CoV-1 and SARS-CoV-2 main proteases by oral antiviral compound AG7404.
Antiviral Res., 208, 2022
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8D7I
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6WAE
 | | Crystal Structure of 6X-His tagged SmcR | | 分子名称: | 1,2-ETHANEDIOL, LuxR family transcriptional regulator, SULFATE ION | | 著者 | Newman, J.D, Russell, M.M, Gonzalez-Gutierrez, G, van Kessel, J.C. | | 登録日 | 2020-03-25 | | 公開日 | 2020-06-17 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | | 主引用文献 | The DNA binding domain of the Vibrio vulnificus SmcR transcription factor is flexible and binds diverse DNA sequences.
Nucleic Acids Res., 49, 2021
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6WAI
 | | Crystal Structure of SmcR N142D from Vibrio vulnificus | | 分子名称: | 1,2-ETHANEDIOL, LuxR family transcriptional regulator, SULFATE ION | | 著者 | Newman, J.D, Russell, M.M, Gonzalez-Gutierrez, G, van Kessel, J.C. | | 登録日 | 2020-03-25 | | 公開日 | 2020-06-17 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.583 Å) | | 主引用文献 | The DNA binding domain of the Vibrio vulnificus SmcR transcription factor is flexible and binds diverse DNA sequences.
Nucleic Acids Res., 49, 2021
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1CQH
 | | HIGH RESOLUTION SOLUTION NMR STRUCTURE OF MIXED DISULFIDE INTERMEDIATE BETWEEN HUMAN THIOREDOXIN (C35A, C62A, C69A, C73A) MUTANT AND A 13 RESIDUE PEPTIDE COMPRISING ITS TARGET SITE IN HUMAN REF-1 (RESIDUES 59-71 OF THE P50 SUBUNIT OF NFKB), NMR, MINIMIZED AVERAGE STRUCTURE | | 分子名称: | REF-1 PEPTIDE, THIOREDOXIN | | 著者 | Clore, G.M, Qin, J, Gronenborn, A.M. | | 登録日 | 1996-04-02 | | 公開日 | 1996-08-01 | | 最終更新日 | 2021-11-03 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The solution structure of human thioredoxin complexed with its target from Ref-1 reveals peptide chain reversal.
Structure, 4, 1996
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4ZS7
 | | Structural mimicry of receptor interaction by antagonistic IL-6 antibodies | | 分子名称: | Interleukin-6, Llama Fab fragment 68F2 heavy chain, Llama Fab fragment 68F2 light chain | | 著者 | Blanchetot, C, De Jonge, N, Desmyter, A, Ongenae, N, Hofman, E, Klarenbeek, A, Sadi, A, Hultberg, A, Kretz-Rommel, A, Spinelli, S, Loris, R, Cambillau, C, de Haard, H. | | 登録日 | 2015-05-13 | | 公開日 | 2016-05-04 | | 最終更新日 | 2016-07-06 | | 実験手法 | X-RAY DIFFRACTION (2.93 Å) | | 主引用文献 | Structural Mimicry of Receptor Interaction by Antagonistic Interleukin-6 (IL-6) Antibodies.
J.Biol.Chem., 291, 2016
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3C9W
 | | Crystal Structure of ERK-2 with hypothemycin covalently bound | | 分子名称: | (1aR,8S,13S,14S,15aR)-5,13,14-trihydroxy-3-methoxy-8-methyl-8,9,13,14,15,15a-hexahydro-6H-oxireno[k][2]benzoxacyclotetradecine-6,12(1aH)-dione, Mitogen-activated protein kinase 1 | | 著者 | Rosenfeld, R.J. | | 登録日 | 2008-02-18 | | 公開日 | 2008-07-08 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Molecular modeling and crystal structure of ERK2-hypothemycin complexes
J.Struct.Biol., 164, 2008
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3AAD
 | | Structure of the histone chaperone CIA/ASF1-double bromodomain complex linking histone modifications and site-specific histone eviction | | 分子名称: | Histone chaperone ASF1A, SULFATE ION, Transcription initiation factor TFIID subunit 1 | | 著者 | Akai, Y, Adachi, N, Hayashi, Y, Eitoku, M, Sano, N, Natsume, R, Kudo, N, Tanokura, M, Senda, T, Horikoshi, M. | | 登録日 | 2009-11-16 | | 公開日 | 2010-04-28 | | 最終更新日 | 2017-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structure of the histone chaperone CIA/ASF1-double bromodomain complex linking histone modifications and site-specific histone eviction
Proc.Natl.Acad.Sci.USA, 107, 2010
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1Y7Y
 | | High-resolution crystal structure of the restriction-modification controller protein C.AhdI from Aeromonas hydrophila | | 分子名称: | C.AhdI | | 著者 | McGeehan, J.E, Streeter, S.D, Papapanagiotou, I, Fox, G.C, Kneale, G.G. | | 登録日 | 2004-12-10 | | 公開日 | 2005-02-22 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | | 主引用文献 | High-resolution crystal structure of the restriction-modification controller protein C.AhdI from Aeromonas hydrophila.
J.Mol.Biol., 346, 2005
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