2XL2

WDR5 IN COMPLEX WITH AN RBBP5 PEPTIDE RECRUITED TO NOVEL SITE

Summary for 2XL2

• Entry DOI: 10.2210/pdb2xl2/pdb
• Related: 2XL3
• Descriptor: WD REPEAT-CONTAINING PROTEIN 5, RETINOBLASTOMA-BINDING PROTEIN 5, GLYCEROL, ... (4 entities in total)
• Functional Keywords: transcription, mll complex, h3k4 methylation, wd-40 beta-propeller
• Biological source: MUS MUSCULUS (MOUSE); More
• Cellular location: Nucleus (By similarity): P61965 Q8BX09
• Total number of polymer chains: 4
• Total formula weight: 76722.30

Authors

Odho, Z.,Southall, S.M.,Wilson, J.R. (deposition date: 2010-07-19, release date: 2010-08-04, Last modification date: 2023-12-20)

• Primary citation: Odho, Z.,Southall, S.M.,Wilson, J.R.; Characterisation of a Novel Wdr5 Binding Site that Recruits Rbbp5 Through a Conserved Motif and Enhances Methylation of H3K4 by Mll1.; J.Biol.Chem., 285:32967-, 2010; PubMed: 20716525; DOI: 10.1074/JBC.M110.159921

Experimental method

X-RAY DIFFRACTION (2.4 Å)