PDB: 71589 件ウェブページステータス検索Chemie searchBIRD

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4IOV	The structure of AAVrh32.33, a Novel Gene Delivery Vector 分子名称: 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, Capsid protein VP1 著者 Mikalism, K, Nam, H.-J, Van vilet, K, Vandenberghe, L.H, Mays, L.E, McKenna, R, Wilson, J, Agbandje-McKenna, M. 登録日 2013-01-08 公開日 2014-04-02 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 The structure of AAVrh32.33, a novel gene delivery vector. J.Struct.Biol., 186, 2014
4C3T	The Carbonic anhydrase from Thermovibrio ammonificans reveals an interesting intermolecular disulfide contributing to increasing thermal stability of this enzyme 分子名称: CARBONATE DEHYDRATASE, CHLORIDE ION, ZINC ION 著者 James, P, Isupov, M, Sayer, C, Berg, S, Lioliou, M, Kotlar, H, Littlechild, J. 登録日 2013-08-27 公開日 2014-09-10 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 The Structure of a Tetrameric [Alpha]-Carbonic Anhydrase from Thermovibrio Ammonificans Reveals a Core Formed Around Intermolecular Disulfides that Contribute to its Thermostability Acta Crystallogr.,Sect.D, 70, 2014
6MWY	The Prp8 intein of Cryptococcus gattii 分子名称: Pre-mRNA-processing-splicing factor 8 著者 Li, Z, Fu, B, Green, C.M, Lang, Y, Zhang, J, Oven, T.S, Li, X, Callahan, B.P, Chaturvedi, S, Belfort, M, Liao, G, Li, H. 登録日 2018-10-30 公開日 2019-11-06 最終更新日 2020-05-20 実験手法 X-RAY DIFFRACTION (2.594 Å) 主引用文献 Cisplatin protects mice from challenge ofCryptococcus neoformansby targeting the Prp8 intein. Emerg Microbes Infect, 8, 2019
4ID4	Crystal structure of chimeric beta-lactamase cTEM-17m 分子名称: Beta-lactamase TEM, Beta-lactamase PSE-4, CHLORIDE ION, ... 著者 Park, J, Gobeil, S, Pelletier, J.N, Berghuis, A.M. 登録日 2012-12-11 公開日 2013-12-25 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.05 Å) 主引用文献 Maintenance of Native-like Protein Dynamics May Not Be Required for Engineering Functional Proteins. Chem.Biol., 21, 2014
4DQ1	Thymidylate synthase from Staphylococcus aureus. 分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, Thymidylate synthase 著者 Osipiuk, J, Holowicki, J, Jedrzejczak, R, Rubin, E, Guinn, K, Ioerger, T, Baker, D, Sacchettini, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Structures of Mtb Proteins Conferring Susceptibility to Known Mtb Inhibitors (MTBI) 登録日 2012-02-14 公開日 2012-03-21 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.71 Å) 主引用文献 Thymidylate synthase from Staphylococcus aureus. To be Published
4DFW	Oxime-based Post Solid-phase Peptide Diversification: Identification of High Affinity Polo-like Kinase 1 (Plk1) Polo-box Domain Binding Peptides 分子名称: CHLORIDE ION, Peptide, Serine/threonine-protein kinase PLK1 著者 Liu, F, Park, J.-E, Qian, W.-J, Lim, D, Gr ber, M, Berg, T, Yaffe, M.B, Lee, K.S, Burke Jr, T.R. 登録日 2012-01-24 公開日 2012-03-28 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Oxime-based Post Solid-phase Peptide Diversification: Identification of High Affinity Polo-like Kinase 1 (Plk1) Polo-box Domain Binding Peptides Chem.Biol., 2012
4DV6	Crystal structure of the Thermus thermophilus 30S ribosomal subunit with a 16S rRNA mutation, A915G 分子名称: 16S rRNA, MAGNESIUM ION, ZINC ION, ... 著者 Demirci, H, Murphy IV, F, Murphy, E, Gregory, S.T, Dahlberg, A.E, Jogl, G. 登録日 2012-02-22 公開日 2013-02-27 実験手法 X-RAY DIFFRACTION (3.297 Å) 主引用文献 A structural basis for streptomycin resistance To be Published
4DV0	Crystal structure of the Thermus thermophilus 30S ribosomal subunit with a 16S rRNA mutation, U20G 分子名称: 16S rRNA, MAGNESIUM ION, ZINC ION, ... 著者 Demirci, H, Murphy IV, F, Murphy, E, Gregory, S.T, Dahlberg, A.E, Jogl, G. 登録日 2012-02-22 公開日 2013-02-27 実験手法 X-RAY DIFFRACTION (3.853 Å) 主引用文献 A structural basis for streptomycin resistance To be Published
4E3S	RB69 DNA Polymerase Ternary Complex with dQTP Opposite dT 分子名称: 3-{2-deoxy-5-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-beta-D-erythro-pentofuranosyl}-7-methyl-3H-imidazo[4,5-b]pyridine, CALCIUM ION, DNA polymerase, ... 著者 Xia, S, Wang, J, Konigsberg, W.H. 登録日 2012-03-10 公開日 2012-05-23 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Probing minor groove hydrogen bonding interactions between RB69 DNA polymerase and DNA. Biochemistry, 51, 2012
4DV1	Crystal structure of the Thermus thermophilus 30S ribosomal subunit with a 16S rRNA mutation, U20G, bound with streptomycin 分子名称: 16S rRNA, MAGNESIUM ION, STREPTOMYCIN, ... 著者 Demirci, H, Murphy IV, F, Murphy, E, Gregory, S.T, Dahlberg, A.E, Jogl, G. 登録日 2012-02-22 公開日 2013-02-27 実験手法 X-RAY DIFFRACTION (3.849 Å) 主引用文献 A structural basis for streptomycin resistance To be Published
6N33	Crystal structure of fms kinase domain with a small molecular inhibitor, PLX5622 分子名称: 6-fluoro-N-[(5-fluoro-2-methoxypyridin-3-yl)methyl]-5-[(5-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]pyridin-2-amine, Macrophage colony-stimulating factor 1 receptor 著者 Zhang, Y. 登録日 2018-11-14 公開日 2019-09-18 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Sustained microglial depletion with CSF1R inhibitor impairs parenchymal plaque development in an Alzheimer's disease model. Nat Commun, 10, 2019
4D5I	Hypocrea jecorina cellobiohydrolase Cel7A E212Q soaked with xylotriose. 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CELLULOSE 1,4-BETA-CELLOBIOSIDASE, COBALT (II) ION, ... 著者 Momeni, M.H, Ubhayasekera, W, Stahlberg, J, Hansson, H. 登録日 2014-11-05 公開日 2015-03-25 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 Structural Insights Into the Inhibition of Cellobiohydrolase Cel7A by Xylooligosaccharides. FEBS J., 282, 2015
5OW6	CryoEM structure of recombinant CMV particles with Tetanus-epitope 分子名称: Capsid protein, VP2, VP3, ... 著者 Kotecha, A, Stuart, D.I, Backmann, M. 登録日 2017-08-30 公開日 2017-09-13 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Incorporation of tetanus-epitope into virus-like particles achieves vaccine responses even in older recipients in models of psoriasis, Alzheimer's and cat allergy. NPJ Vaccines, 2, 2017
4IUZ	High resolution crystal structure of racemic ester insulin 分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, Insulin A chain, ... 著者 Avital-Shmilovici, M, Mandal, K, Gates, Z.P, Phillips, N, Weiss, M.A, Kent, S.B.H. 登録日 2013-01-22 公開日 2013-02-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Fully Convergent Chemical Synthesis of Ester Insulin: Determination of the High Resolution X-ray Structure by Racemic Protein Crystallography. J.Am.Chem.Soc., 135, 2013
4D0Z	GalNAc-T2 crystal soaked with UDP-5SGalNAc, mEA2 and manganese (Higher resolution dataset) 分子名称: (2R,3R,4R,5R,6R)-3-(acetylamino)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-thiopyran-2-yl [(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-5-thio-alpha-D-galactopyranose, ... 著者 Lira-Navarrete, E, Iglesias-Fernandez, J, Zandberg, W.F, Companon, I, Kong, Y, Corzana, F, Pinto, B.M, Clausen, H, Peregrina, J.M, Vocadlo, D, Rovira, C, Hurtado-Guerrero, R. 登録日 2014-04-30 公開日 2014-05-28 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Substrate-Guided Front-Face Reaction Revealed by Combined Structural Snapshots and Metadynamics for the Polypeptide N- Acetylgalactosaminyltransferase 2. Angew.Chem.Int.Ed.Engl., 53, 2014
4CU5	C-terminal domain of endolysin from phage CD27L is a trigger and release factor 分子名称: ENDOLYSIN 著者 Dunne, M, Mertens, H.D.T, Garefalaki, V, Jeffries, C.M, Thompson, A, Lemke, E.A, Svergun, D.I, Mayer, M.J, Narbad, A, Meijers, R. 登録日 2014-03-17 公開日 2014-08-06 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.24 Å) 主引用文献 The Cd27L and Ctp1L Endolysins Targeting Clostridia Contain a Built-in Trigger and Release Factor. Plos Pathog., 10, 2014
4D5O	Hypocrea jecorina cellobiohydrolase Cel7A E212Q soaked with xylopentaose. 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CELLULOSE 1,4-BETA-CELLOBIOSIDASE, COBALT (II) ION, ... 著者 Momeni, M.H, Ubhayasekera, W, Stahlberg, J, Hansson, H. 登録日 2014-11-07 公開日 2015-03-25 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.52 Å) 主引用文献 Structural Insights Into the Inhibition of Cellobiohydrolase Cel7A by Xylooligosaccharides. FEBS J., 282, 2015
4J19	Structure of a novel telomere repeat binding protein bound to DNA 分子名称: CHLORIDE ION, DNA (5'-D(*CP*TP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*G)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*CP*CP*CP*TP*AP*AP*CP*CP*CP*TP*AP*AP*CP*A)-3'), ... 著者 Kappei, D, Butter, F, Benda, C, Scheibe, M, Draskovic, I, Stevense, M, Lopes Novo, C, Basquin, C, Krastev, D.B, Kittler, R, Jessberger, R, Londono-Vallejo, A.J, Mann, M, Buchholz, F. 登録日 2013-02-01 公開日 2013-05-29 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 HOT1 is a mammalian direct telomere repeat-binding protein contributing to telomerase recruitment. Embo J., 32, 2013
4CPS	Macrocyclic Transition-State Mimicking HIV-1 Protease Inhibitors Encompassing a Tertiary Alcohol 分子名称: CHLORIDE ION, PROTEASE, methyl [(2S)-1-(2-{3-[(3R,6S,10Z)-3-hydroxy-4,7-dioxo-6-(propan-2-yl)-5,8-diazabicyclo[11.2.2]heptadeca-1(15),10,13,16-tetraen-3-yl]propyl}-2-[4-(pyridin-3-yl)benzyl]hydrazinyl)-3,3-dimethyl-1-oxobutan-2-yl]carbamate 著者 DeRosa, M, Unge, J, Motwani, H.V, Rosenquist, A, Vrang, L, Wallberg, H, Larhed, M. 登録日 2014-02-08 公開日 2014-12-17 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Synthesis of P1'-Functionalized Macrocyclic Transition-State Mimicking HIV-1 Protease Inhibitors Encompassing a Tertiary Alcohol. J.Med.Chem., 57, 2014
4DV7	Crystal structure of the Thermus thermophilus 30S ribosomal subunit with a 16S rRNA mutation, A915G, bound with streptomycin 分子名称: 16S rRNA, MAGNESIUM ION, STREPTOMYCIN, ... 著者 Demirci, H, Murphy IV, F, Murphy, E, Gregory, S.T, Dahlberg, A.E, Jogl, G. 登録日 2012-02-22 公開日 2013-02-27 実験手法 X-RAY DIFFRACTION (3.294 Å) 主引用文献 A structural basis for streptomycin resistance To be Published
4DEM	Crystal structure of human FPPS in complex with YS_04_70 分子名称: Farnesyl pyrophosphate synthase, MAGNESIUM ION, [({4-[4-(propan-2-yloxy)phenyl]pyridin-2-yl}amino)methanediyl]bis(phosphonic acid) 著者 Park, J, Lin, Y.-S, Tsantrizos, Y.S, Berghuis, A.M. 登録日 2012-01-20 公開日 2012-03-21 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Design and Synthesis of Active Site Inhibitors of the Human Farnesyl Pyrophosphate Synthase: Apoptosis and Inhibition of ERK Phosphorylation in Multiple Myeloma Cells. J.Med.Chem., 55, 2012
4IBT	Human p53 core domain with hot spot mutation R273H and second-site suppressor mutation T284R 分子名称: Cellular tumor antigen p53, ZINC ION 著者 Diskin-Posner, Y, Eldar, A, Rozenberg, H, Shakked, Z. 登録日 2012-12-09 公開日 2013-08-14 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural studies of p53 inactivation by DNA-contact mutations and its rescue by suppressor mutations via alternative protein-DNA interactions. Nucleic Acids Res., 41, 2013
4DHJ	The structure of a ceOTUB1 ubiquitin aldehyde UBC13~Ub complex 分子名称: Ubiquitin, Ubiquitin aldehyde, Ubiquitin thioesterase otubain-like, ... 著者 Wiener, R, Zhang, X, Wang, T, Wolberger, C. 登録日 2012-01-27 公開日 2012-02-22 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 The mechanism of OTUB1-mediated inhibition of ubiquitination. Nature, 483, 2012
4IPY	HIV capsid C-terminal domain 分子名称: 1,2-ETHANEDIOL, Capsid protein p24 著者 Lampel, A, Yaniv, O, Berger, O, Bachrach, E, Gazit, E, Frolow, F. 登録日 2013-01-10 公開日 2013-10-16 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 A triclinic crystal structure of the carboxy-terminal domain of HIV-1 capsid protein with four molecules in the asymmetric unit reveals a novel packing interface. Acta Crystallogr.,Sect.F, 69, 2013
4DR2	Crystal structure of the Thermus thermophilus (HB8) 30S ribosomal subunit with multiple copies of paromomycin molecules bound 分子名称: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... 著者 Demirci, H, Murphy IV, F, Murphy, E, Gregory, S.T, Dahlberg, A.E, Jogl, G. 登録日 2012-02-16 公開日 2012-11-14 最終更新日 2013-01-30 実験手法 X-RAY DIFFRACTION (3.249 Å) 主引用文献 A structural basis for streptomycin-induced misreading of the genetic code. Nat Commun, 4, 2013

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