4C3T

The Carbonic anhydrase from Thermovibrio ammonificans reveals an interesting intermolecular disulfide contributing to increasing thermal stability of this enzyme

Summary for 4C3T

Entry DOI	10.2210/pdb4c3t/pdb
Descriptor	CARBONATE DEHYDRATASE, ZINC ION, CHLORIDE ION, ... (4 entities in total)
Functional Keywords	lyase, thermophilic, acetazolamide, carbon dioxide capture, thermal stability
Biological source	THERMOVIBRIO AMMONIFICANS
Total number of polymer chains	2
Total formula weight	55653.52
Authors	James, P.,Isupov, M.,Sayer, C.,Berg, S.,Lioliou, M.,Kotlar, H.,Littlechild, J. (deposition date: 2013-08-27, release date: 2014-09-10, Last modification date: 2023-12-20)
Primary citation	James, P.,Isupov, M.N.,Sayer, C.,Saneei, V.,Berg, S.,Lioliou, M.,Kotlar, H.,Littlechild, J. The Structure of a Tetrameric [Alpha]-Carbonic Anhydrase from Thermovibrio Ammonificans Reveals a Core Formed Around Intermolecular Disulfides that Contribute to its Thermostability Acta Crystallogr.,Sect.D, 70:2607-, 2014 Cited by PubMed: 25286845 DOI: 10.1107/S1399004714016526 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.69 Å)

Structure validation