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6E51
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Crystal structure of the apo domain-swapped dimer Q108K:K40L:T51W mutant of human cellular retinol binding protein II
分子名称: Retinol-binding protein 2
著者Ghanbarpour, A, Geiger, J.
登録日2018-07-19
公開日2019-10-16
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.256 Å)
主引用文献Engineering the hCRBPII Domain-Swapped Dimer into a New Class of Protein Switches.
J.Am.Chem.Soc., 141, 2019
6E50
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BU of 6e50 by Molmil
Crystal structure of the apo domain-swapped dimer Q108K:K40L:T51F mutant of human Cellular Retinol Binding Protein II
分子名称: ACETATE ION, Retinol-binding protein 2
著者Ghanbarpour, A, Geiger, J.
登録日2018-07-18
公開日2019-10-16
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.965 Å)
主引用文献Engineering the hCRBPII Domain-Swapped Dimer into a New Class of Protein Switches.
J.Am.Chem.Soc., 141, 2019
3MI7
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BU of 3mi7 by Molmil
An Enhanced Repressor of Human Papillomavirus E2 Protein
分子名称: 1,2-ETHANEDIOL, Regulatory protein E2
著者Bohm, A, Baleja, J, Bose, K, Meinke, G.
登録日2010-04-09
公開日2011-04-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Design and characterization of an enhanced repressor of human papillomavirus E2 protein.
Faseb J., 25, 2011
4PRX
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BU of 4prx by Molmil
E. coli GyrB 43-kDa N-terminal fragment in complex with ADP+Pi
分子名称: ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, GyrB, ...
著者Stanger, F.V, Schirmer, T.
登録日2014-03-06
公開日2014-09-24
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of the N-Terminal Gyrase B Fragment in Complex with ADPPi Reveals Rigid-Body Motion Induced by ATP Hydrolysis
Plos One, 9, 2014
5CWA
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BU of 5cwa by Molmil
Structure of Anthranilate Synthase Component I (TrpE) from Mycobacterium tuberculosis with inhibitor bound
分子名称: 3-{[(1Z)-1-carboxyprop-1-en-1-yl]oxy}-2-hydroxybenzoic acid, Anthranilate synthase component 1, GLYCEROL, ...
著者Johnston, J.M, Bashiri, G, Evans, G.L, Lott, J.S, Baker, E.N.
登録日2015-07-28
公開日2015-08-12
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure and inhibition of subunit I of the anthranilate synthase complex of Mycobacterium tuberculosis and expression of the active complex.
Acta Crystallogr.,Sect.D, 71, 2015
6GIR
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BU of 6gir by Molmil
Arabidopsis thaliana cytosolic seryl-tRNA synthetase
分子名称: Serine--tRNA ligase, cytoplasmic
著者Kekez, I, Kekez, M, Rokov-Plavec, J, Matkovic-Calogovic, D.
登録日2018-05-15
公開日2019-01-02
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.343 Å)
主引用文献Arabidopsis seryl-tRNA synthetase: the first crystal structure and novel protein interactor of plant aminoacyl-tRNA synthetase.
FEBS J., 286, 2019
7QZ6
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BU of 7qz6 by Molmil
Transcriptional regulator LmrR with bound daunomycin and with Trp-67 and Trp-96 replaced by 5-fluoroTrp
分子名称: DAUNOMYCIN, Transcriptional regulator, PadR-like family
著者Thunnissen, A.M.W.H.
登録日2022-01-30
公開日2022-11-23
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献The Role of Tryptophan in pi Interactions in Proteins: An Experimental Approach.
J.Am.Chem.Soc., 144, 2022
7QZ8
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Transcriptional regulator LmrR with bound daunomycin and with Trp-67 and Trp-96 replaced by the unnatural amino acid 5,6-difluoroTrp
分子名称: DAUNOMYCIN, Transcriptional regulator, PadR-like family
著者Thunnissen, A.M.W.H.
登録日2022-01-30
公開日2022-11-23
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The Role of Tryptophan in pi Interactions in Proteins: An Experimental Approach.
J.Am.Chem.Soc., 144, 2022
7QZ7
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BU of 7qz7 by Molmil
Transcriptional regulator LmrR with bound daunomycin and with Trp-67 and Trp-96 replaced by 5,6,7-trifluoroTrp
分子名称: DAUNOMYCIN, Transcriptional regulator, PadR-like family
著者Thunnissen, A.M.W.H.
登録日2022-01-30
公開日2022-11-23
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The Role of Tryptophan in pi Interactions in Proteins: An Experimental Approach.
J.Am.Chem.Soc., 144, 2022
6G79
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Coupling specificity of heterotrimeric Go to the serotonin 5-HT1B receptor
分子名称: 2-[5-[2-[4-(4-cyanophenyl)piperazin-1-yl]-2-oxidanylidene-ethoxy]-1~{H}-indol-3-yl]ethylazanium, 5-hydroxytryptamine receptor 1B, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Garcia-Nafria, J, Nehme, R, Edwards, P, Tate, C.G.
登録日2018-04-05
公開日2018-06-20
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (3.78 Å)
主引用文献Cryo-EM structure of the serotonin 5-HT1Breceptor coupled to heterotrimeric Go.
Nature, 558, 2018
7QZ9
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BU of 7qz9 by Molmil
Transcriptional regulator LmrR with Trp-67 and Trp-96 replaced by the unnatural amino acid 5,6-difluoroTrp
分子名称: Transcriptional regulator, PadR-like family
著者Thunnissen, A.M.W.H.
登録日2022-01-30
公開日2022-11-23
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献The Role of Tryptophan in pi Interactions in Proteins: An Experimental Approach.
J.Am.Chem.Soc., 144, 2022
7QZ5
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BU of 7qz5 by Molmil
Transcriptional regulator LmrR with Trp-67 and Trp-96 replaced by the unnatural amino acid 5-fluoroTrp
分子名称: Transcriptional regulator, PadR-like family
著者Thunnissen, A.M.W.H.
登録日2022-01-30
公開日2022-11-23
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The Role of Tryptophan in pi Interactions in Proteins: An Experimental Approach.
J.Am.Chem.Soc., 144, 2022
5V91
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Crystal structure of fosfomycin resistance protein from Klebsiella pneumoniae
分子名称: Fosfomycin resistance protein, ZINC ION
著者Klontz, E, Guenther, S, Silverstein, Z, Sundberg, E.
登録日2017-03-22
公開日2017-08-30
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Structure and Dynamics of FosA-Mediated Fosfomycin Resistance in Klebsiella pneumoniae and Escherichia coli.
Antimicrob. Agents Chemother., 61, 2017
1Y5W
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BU of 1y5w by Molmil
tRNA-guanine Transglycosylase (TGT) in complex with 6-Amino-4-[2-(4-methylphenyl)ethyl]-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one
分子名称: 6-AMINO-4-[2-(4-METHYLPHENYL)ETHYL]-1,7-DIHYDRO-8H-IMIDAZO[4,5-G]QUINAZOLIN-8-ONE, GLYCEROL, Queuine tRNA-ribosyltransferase, ...
著者Stengl, B, Meyer, E.A, Heine, A, Brenk, R, Diederich, F, Klebe, G.
登録日2004-12-03
公開日2005-12-13
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Crystal structures of tRNA-guanine transglycosylase (TGT) in complex with novel and potent inhibitors unravel pronounced induced-fit adaptations and suggest dimer formation upon substrate binding
J.Mol.Biol., 370, 2007
4PS4
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BU of 4ps4 by Molmil
Crystal structure of the complex between IL-13 and M1295 FAB
分子名称: Interleukin-13, M1295 HEAVY CHAIN, M1295 LIGHT CHAIN
著者Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L.
登録日2014-03-06
公開日2014-03-19
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Human Framework Adaptation of a Mouse Anti-Human Il-13 Antibody.
J.Mol.Biol., 398, 2010
5UTG
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BU of 5utg by Molmil
Red abalone lysin F104A
分子名称: Egg-lysin
著者Wilburn, D.B, Tuttle, L.M.
登録日2017-02-14
公開日2018-01-31
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structure of sperm lysin yields novel insights into molecular dynamics of rapid protein evolution.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5ABV
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BU of 5abv by Molmil
Complex of D. melanogaster eIF4E with the 4E-binding protein Mextli
分子名称: EUKARYOTIC TRANSLATION INITIATION FACTOR 4E, GH11071P
著者Peter, D, Weichenrieder, O.
登録日2015-08-09
公開日2015-09-02
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Mextli Proteins Use Both Canonical Bipartite and Novel Tripartite Binding Modes to Form Eif4E Complexes that Display Differential Sensitivity to 4E-BP Regulation
Genes Dev., 29, 2015
4PN6
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BU of 4pn6 by Molmil
Structure of the Cytomegalovirus-Encoded m04 Glycoprotein
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, M04, ...
著者Berry, R, Rossjohn, J.
登録日2014-05-23
公開日2014-07-23
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The Structure of the Cytomegalovirus-Encoded m04 Glycoprotein, a Prototypical Member of the m02 Family of Immunoevasins.
J.Biol.Chem., 289, 2014
4POY
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BU of 4poy by Molmil
Engineered Dual Specific VHH antibody
分子名称: VHH-metal
著者Fanning, S.W, Walter, R, Horn, J.R.
登録日2014-02-26
公開日2014-09-24
最終更新日2014-10-22
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural basis of an engineered dual-specific antibody: conformational diversity leads to a hypervariable loop metal-binding site.
Protein Eng.Des.Sel., 27, 2014
6FV5
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BU of 6fv5 by Molmil
QTRT2, the non-catalytic subunit of murine tRNA-Guanine Transglycosylase
分子名称: DI(HYDROXYETHYL)ETHER, MALONATE ION, Queuine tRNA-ribosyltransferase accessory subunit 2, ...
著者Behrens, C, Heine, A, Reuter, K.
登録日2018-03-01
公開日2018-06-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.179 Å)
主引用文献Homodimer Architecture of QTRT2, the Noncatalytic Subunit of the Eukaryotic tRNA-Guanine Transglycosylase.
Biochemistry, 57, 2018
4PRV
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BU of 4prv by Molmil
E. coli GyrB 43-kDa N-terminal fragment in complex with ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, GyrB, MAGNESIUM ION
著者Stanger, F.V, Schirmer, T.
登録日2014-03-06
公開日2014-09-24
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of the N-Terminal Gyrase B Fragment in Complex with ADPPi Reveals Rigid-Body Motion Induced by ATP Hydrolysis
Plos One, 9, 2014
4PPT
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BU of 4ppt by Molmil
Engineered Dual Specific VHH Antibody in Complex with a Nickel (II) Ion
分子名称: Engineered single domain VHH antibody, NICKEL (II) ION, SULFATE ION
著者Fanning, S.W, Walter, R, Horn, J.R.
登録日2014-02-27
公開日2014-09-03
最終更新日2014-10-22
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural basis of an engineered dual-specific antibody: conformational diversity leads to a hypervariable loop metal-binding site.
Protein Eng.Des.Sel., 27, 2014
6FZO
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BU of 6fzo by Molmil
SMURFP-Y56F mutant
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, SULFATE ION, ...
著者Janowski, R, Fuenzalida-Wernera, J.P, Mishra, K, Vetschera, P, Weidenfeld, I, Richter, K, Niessing, D, Ntziachristos, V, Stiel, A.C.
登録日2018-03-15
公開日2018-10-17
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of a biliverdin-bound phycobiliprotein: Interdependence of oligomerization and chromophorylation.
J. Struct. Biol., 204, 2018
3B3Q
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Crystal structure of a synaptic adhesion complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Chen, X, Liu, H, Shim, A, Focia, P, He, X.
登録日2007-10-22
公開日2008-01-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis for synaptic adhesion mediated by neuroligin-neurexin interactions.
Nat.Struct.Mol.Biol., 15, 2008
3B5G
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Crystal Structure of the Unstable and Highly Fibrillogenic PRO7SER Mutant of the Recombinant Variable Domain 6AJL2
分子名称: ACETATE ION, AMYLOID LAMBDA 6 LIGHT CHAIN VARIABLE REGION PIP, GLYCEROL, ...
著者Hernandez-Santoyo, A, Rodriguez-Romero, A.
登録日2007-10-25
公開日2008-11-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A single mutation at the sheet switch region results in conformational changes favoring lambda6 light-chain fibrillogenesis.
J.Mol.Biol., 396, 2010

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