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7TKU
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BU of 7tku by Molmil
Structure of the yeast clamp loader (Replication Factor C RFC) bound to the open sliding clamp (Proliferating Cell Nuclear Antigen PCNA)
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
著者Gaubitz, C, Liu, X, Pajak, J, Stone, N, Hayes, J, Demo, G, Kelch, B.A.
登録日2022-01-17
公開日2022-02-16
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Cryo-EM structures reveal high-resolution mechanism of a DNA polymerase sliding clamp loader.
Elife, 11, 2022
7THV
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BU of 7thv by Molmil
Structure of the yeast clamp loader (Replication Factor C RFC) bound to the sliding clamp (Proliferating Cell Nuclear Antigen PCNA) in an autoinhibited conformation
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
著者Gaubitz, C, Liu, X, Pajak, J, Stone, N, Hayes, J, Demo, G, Kelch, B.A.
登録日2022-01-12
公開日2022-02-16
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Cryo-EM structures reveal high-resolution mechanism of a DNA polymerase sliding clamp loader.
Elife, 11, 2022
7THJ
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BU of 7thj by Molmil
Structure of the yeast clamp loader (Replication Factor C RFC) bound to the sliding clamp (Proliferating Cell Nuclear Antigen PCNA) in an autoinhibited conformation
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
著者Gaubitz, C, Liu, X, Pajak, J, Stone, N, Hayes, J, Demo, G, Kelch, B.A.
登録日2022-01-11
公開日2022-02-16
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Cryo-EM structures reveal high-resolution mechanism of a DNA polymerase sliding clamp loader.
Elife, 11, 2022
9G7H
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BU of 9g7h by Molmil
Human Sirt6 in complex with ADP-ribose and the inhibitor 2-Pr
分子名称: 2,4-bis(oxidanylidene)-1-[2-oxidanylidene-2-[[(2S)-3-oxidanylidene-3-(propylamino)-2-[3-(3-pyridin-3-yl-1,2,4-oxadiazol-5-yl)propanoylamino]propyl]amino]ethyl]pyrimidine-5-carboxamide, NAD-dependent protein deacetylase sirtuin-6, SULFATE ION, ...
著者You, W, Steegborn, C.
登録日2024-07-21
公開日2024-08-14
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Elucidating the Unconventional Binding Mode of a DNA-Encoded Library Hit Provides a Blueprint for Sirtuin 6 Inhibitor Development.
Chemmedchem, 2024
7DE9
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BU of 7de9 by Molmil
crystal structure of Arabidopsis RDM15 tudor domain in complex with an H3K4me1 peptide
分子名称: Histone H3.2, Transcriptional regulator
著者Song, Z, Du, J.
登録日2020-11-03
公開日2021-04-07
最終更新日2021-06-23
実験手法X-RAY DIFFRACTION (1.711 Å)
主引用文献A histone H3K4me1-specific binding protein is required for siRNA accumulation and DNA methylation at a subset of loci targeted by RNA-directed DNA methylation.
Nat Commun, 12, 2021
6MJ1
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BU of 6mj1 by Molmil
Crystal structure of RefZ (regulator of FtsZ) from Bacillus subtilis
分子名称: Probable HTH-type transcriptional regulator YttP
著者Krieger, I.V, Brown, E.E, Herman, J.K, Sacchettini, J.C.
登録日2018-09-20
公開日2019-03-20
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A DNA-Binding Protein Tunes Septum Placement during Bacillus subtilis Sporulation.
J.Bacteriol., 201, 2019
5E24
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BU of 5e24 by Molmil
Structure of the Su(H)-Hairless-DNA Repressor Complex
分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*AP*AP*TP*CP*TP*TP*TP*CP*CP*CP*AP*CP*AP*GP*T)-3'), DNA (5'-D(*TP*TP*AP*CP*TP*GP*TP*GP*GP*GP*AP*AP*AP*GP*A)-3'), ...
著者Kovall, R.A, Yuan, Z.
登録日2015-09-30
公開日2016-06-15
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Structure and Function of the Su(H)-Hairless Repressor Complex, the Major Antagonist of Notch Signaling in Drosophila melanogaster.
Plos Biol., 14, 2016
6XLK
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BU of 6xlk by Molmil
Cryo-EM structure of EcmrR-DNA complex in EcmrR-RPitc-4nt
分子名称: CHAPSO, MerR family transcriptional regulator EcmrR, TETRAPHENYLANTIMONIUM ION, ...
著者Yang, Y, Liu, C, Liu, B.
登録日2020-06-28
公開日2021-04-07
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural visualization of transcription activated by a multidrug-sensing MerR family regulator.
Nat Commun, 12, 2021
6XLA
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BU of 6xla by Molmil
Cryo-EM structure of EcmrR-DNA complex in EcmrR-RPitc-3nt
分子名称: MerR family transcriptional regulator EcmrR, TETRAPHENYLANTIMONIUM ION, synthetic non-template strand DNA (54-MER), ...
著者Yang, Y, Liu, C, Shi, W, Liu, B.
登録日2020-06-28
公開日2021-04-07
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural visualization of transcription activated by a multidrug-sensing MerR family regulator.
Nat Commun, 12, 2021
6XL6
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BU of 6xl6 by Molmil
Cryo-EM structure of EcmrR-DNA complex in EcmrR-RPo
分子名称: CHAPSO, MerR family transcriptional regulator EcmrR, TETRAPHENYLANTIMONIUM ION, ...
著者Yang, Y, Liu, C, Liu, B.
登録日2020-06-28
公開日2021-04-07
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural visualization of transcription activated by a multidrug-sensing MerR family regulator.
Nat Commun, 12, 2021
8QJ7
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BU of 8qj7 by Molmil
Cryo-EM structure of human DNA polymerase alpha-primase in pre-initiation stage 1
分子名称: ADENOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, ...
著者Yin, Z, Pellegrini, L.
登録日2023-09-12
公開日2024-02-21
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.07 Å)
主引用文献CryoEM insights into RNA primer synthesis by the human primosome.
Febs J., 291, 2024
5NKL
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BU of 5nkl by Molmil
Crystal structure of the large fragment of DNA polymerase I from Thermus Aquaticus in a closed ternary complex with the artificial base pair dDs-dPxTP
分子名称: ACETATE ION, DNA (5'-D(*AP*AP*AP*(DNU)P*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3'), ...
著者Betz, K, Marx, A, Diederichs, K, Hirao, I, Kimoto, M.
登録日2017-03-31
公開日2017-06-28
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural Basis for Expansion of the Genetic Alphabet with an Artificial Nucleobase Pair.
Angew. Chem. Int. Ed. Engl., 56, 2017
1EFA
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BU of 1efa by Molmil
CRYSTAL STRUCTURE OF THE LAC REPRESSOR DIMER BOUND TO OPERATOR AND THE ANTI-INDUCER ONPF
分子名称: 2-nitrophenyl beta-D-fucopyranoside, DNA (5'-D(*GP*AP*AP*T*TP*GP*TP*GP*AP*GP*CP*GP*CP*TP*CP*AP*CP*AP*AP*TP*T)-3'), LAC REPRESSOR
著者Bell, C.E, Lewis, M.
登録日2000-02-07
公開日2000-03-06
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A closer view of the conformation of the Lac repressor bound to operator.
Nat.Struct.Biol., 7, 2000
5HSZ
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BU of 5hsz by Molmil
Structure of the K. pneumonia SlmA protein bound to the C-terminal tail of the cytoskeletal cell division protein FtsZ
分子名称: C-terminal Tail of FtsZ, Nucleoid occlusion factor SlmA, SULFATE ION
著者Zeng, W, Schumacher, M.A.
登録日2016-01-26
公開日2016-04-13
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structures of the nucleoid occlusion protein SlmA bound to DNA and the C-terminal domain of the cytoskeletal protein FtsZ.
Proc.Natl.Acad.Sci.USA, 113, 2016
5YBC
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BU of 5ybc by Molmil
X-ray structure of native ETS-domain domain of Ergp55
分子名称: GLYCEROL, Transcriptional regulator ERG
著者Saxena, A.K, Gangwar, S.P.
登録日2017-09-04
公開日2018-09-19
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Comparative structure analysis of the ETSi domain of ERG3 and its complex with the E74 promoter DNA sequence
Acta Crystallogr F Struct Biol Commun, 74, 2018
4A3F
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BU of 4a3f by Molmil
RNA Polymerase II initial transcribing complex with a 6nt DNA-RNA hybrid and soaked with AMPCPP
分子名称: 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP*CP*TP*TP*DTP *TP*TP*CP*C BRU*GP*GP*TP*CP*AP*TP*T)-3', DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, ...
著者Cheung, A.C.M, Sainsbury, S, Cramer, P.
登録日2011-09-30
公開日2011-12-07
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structural basis of initial RNA polymerase II transcription.
EMBO J., 30, 2011
4A3J
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BU of 4a3j by Molmil
RNA Polymerase II initial transcribing complex with a 2nt DNA-RNA hybrid and soaked with GMPCPP
分子名称: 5'-D(*AP*GP*CP*TP*AP*GP*CP*TP*TP*TP*CP*BRUP*AP*CP*CP *TP*GP*AP*AP*CP*AP*AP*CP*TP*AP*AP*CP)-3', 5'-D(*GP*TP*AP*GP*AP*AP*AP*GP*CP*TP*AP*GP*CP*TP)-3', 5'-R(*CP*AP)-3', ...
著者Cheung, A.C.M, Sainsbury, S, Cramer, P.
登録日2011-09-30
公開日2011-12-07
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Structural Basis of Initial RNA Polymerase II Transcription.
Embo J., 30, 2011
4A3E
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BU of 4a3e by Molmil
RNA Polymerase II initial transcribing complex with a 5nt DNA-RNA hybrid and soaked with AMPCPP
分子名称: DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, ...
著者Cheung, A.C.M, Sainsbury, S, Cramer, P.
登録日2011-09-30
公開日2011-12-07
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structural basis of initial RNA polymerase II transcription.
EMBO J., 30, 2011
4A3M
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BU of 4a3m by Molmil
RNA Polymerase II initial transcribing complex with a 4nt DNA-RNA hybrid and soaked with AMPCPP
分子名称: 5'-D(*AP*AP*GP*TP*AP*CP*TP)-3', 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP*CP*TP*TP*TP* TP*TP*CP*CP*BRUP*GP*GP*TP*CP*AP*TP*T)-3', 5'-R(*AP*GP*GP*A)-3', ...
著者Cheung, A.C.M, Sainsbury, S, Cramer, P.
登録日2011-09-30
公開日2011-12-07
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.9 Å)
主引用文献Structural basis of initial RNA polymerase II transcription.
EMBO J., 30, 2011
4A3L
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BU of 4a3l by Molmil
RNA Polymerase II initial transcribing complex with a 7nt DNA-RNA hybrid and soaked with AMPCPP
分子名称: 5'-D(*AP*AP*GP*TP*AP*CP*TP)-3', 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP*CP*TP*TP*TP *TP*TP*CP*CP*BRU*GP*GP*TP*CP*AP*TP*T)-3', 5'-R(*AP*CP*CP*AP*GP*GP*AP)-3', ...
著者Cheung, A.C.M, Sainsbury, S, Cramer, P.
登録日2011-09-30
公開日2011-12-07
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structural basis of initial RNA polymerase II transcription.
EMBO J., 30, 2011
4A3K
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BU of 4a3k by Molmil
RNA Polymerase II initial transcribing complex with a 7nt DNA-RNA hybrid
分子名称: 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP*CP*TP*TP*DTP *TP*TP*CP*CP*BRU*GP*GP*TP*CP*AP*TP*T)-3', 5'-D(*TP*AP*AP*GP*TP*AP*CP*TP*TP*GP*AP)-3', 5'-R(*AP*CP*CP*AP*GP*GP*AP)-3', ...
著者Cheung, A.C.M, Sainsbury, S, Cramer, P.
登録日2011-09-30
公開日2011-12-07
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structural Basis of Initial RNA Polymerase II Transcription.
Embo J., 30, 2011
8XAX
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BU of 8xax by Molmil
Cryo-EM structure of an anti-phage defense complex bound to AMPPNP and DNA at state 2
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-binding protein, DUF4297, ...
著者An, Q, Deng, Z.
登録日2023-12-05
公開日2024-06-05
最終更新日2024-08-14
実験手法ELECTRON MICROSCOPY (2.92 Å)
主引用文献Molecular and structural basis of an ATPase-nuclease dual-enzyme anti-phage defense complex.
Cell Res., 34, 2024
8XAW
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BU of 8xaw by Molmil
Cryo-EM structure of an anti-phage defense complex bound to AMPPNP and DNA at state 1
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-binding protein, DUF4297, ...
著者An, Q, Deng, Z.
登録日2023-12-05
公開日2024-06-05
最終更新日2024-08-14
実験手法ELECTRON MICROSCOPY (2.73 Å)
主引用文献Molecular and structural basis of an ATPase-nuclease dual-enzyme anti-phage defense complex.
Cell Res., 34, 2024
4F4N
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BU of 4f4n by Molmil
Crystal structure of 2-se-thymidine derivatized dna 8mer
分子名称: 5'-D(*GP*TP*GP*(US3)P*AP*CP*AP*C)-3'
著者Zhang, W, Sheng, J, Huang, Z.
登録日2012-05-10
公開日2012-06-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Crystal structure of 2-se-thymidine derivatized dna 8mer
TO BE PUBLISHED
5N07
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BU of 5n07 by Molmil
Structure of the [4Fe-4S] form of the NO response regulator NsrR
分子名称: CHLORIDE ION, HTH-type transcriptional repressor NsrR, IRON/SULFUR CLUSTER, ...
著者Volbeda, A, Fontecilla-Camps, J.C.
登録日2017-02-02
公開日2017-04-26
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structures of the NO sensor NsrR reveal how its iron-sulfur cluster modulates DNA binding.
Nat Commun, 8, 2017

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件を2024-09-04に公開中

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