4A3E

RNA Polymerase II initial transcribing complex with a 5nt DNA-RNA hybrid and soaked with AMPCPP

Summary for 4A3E

Related1TWC 4A3K 1Y77 1R9S 1TWG 1SFO 4A3F 1I50 4A3D 1R5U 1DZF 1Y14 1Y1W 1NT9 1I3Q 1PQV 1TWF 4A3G 4A3C 4A3I 4A3B 1I6H 1Y1V 1Y1Y 1WCM 4A3M 1TWA 1NIK 2VUM 1TWH 1R9T 2JA7 2JA6 4A3L 1A1D 1K83 2B63 2B8K 2JA8 2JA5 4A3J
DescriptorDNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB3, ... (18 entities in total)
Functional Keywordstranscription, transcription initiation
Biological sourceSACCHAROMYCES CEREVISIAE (BAKER'S YEAST)
Total number of polymer chains15
Total molecular weight528941.66
Authors
Cheung, A.C.M.,Sainsbury, S.,Cramer, P. (deposition date: 2011-09-30, release date: 2011-12-07, Last modification date: 2019-10-09)
Primary citation
Cheung, A.C.,Sainsbury, S.,Cramer, P.
Structural basis of initial RNA polymerase II transcription.
EMBO J., 30:4755-4763, 2011
PubMed: 22056778 (PDB entries with the same primary citation)
DOI: 10.1038/emboj.2011.396
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3.4 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliersRNA backbone 0.2068 3.6% 13.8% 2.8% 0.53MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution