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5WYJ
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BU of 5wyj by Molmil
Cryo-EM structure of the 90S small subunit pre-ribosome (Dhr1-depleted, Enp1-TAP, state 1)
分子名称: 13 kDa ribonucleoprotein-associated protein, 18S ribosomal RNA, 40S ribosomal protein S1-A, ...
著者Ye, K, Zhu, X, Sun, Q.
登録日2017-01-13
公開日2017-03-29
最終更新日2019-10-09
実験手法ELECTRON MICROSCOPY (8.7 Å)
主引用文献Molecular architecture of the 90S small subunit pre-ribosome.
Elife, 6, 2017
5WVO
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BU of 5wvo by Molmil
Crystal structure of DNMT1 RFTS domain in complex with K18/K23 mono-ubiquitylated histone H3
分子名称: DNA (cytosine-5)-methyltransferase 1, Histone H3.1, Ubiquitin, ...
著者Ishiyama, S, Nishiyama, A, Nakanishi, M, Arita, K.
登録日2016-12-28
公開日2017-11-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.997 Å)
主引用文献Structure of the Dnmt1 Reader Module Complexed with a Unique Two-Mono-Ubiquitin Mark on Histone H3 Reveals the Basis for DNA Methylation Maintenance
Mol. Cell, 68, 2017
5UDH
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BU of 5udh by Molmil
HHARI/ARIH1-UBCH7~Ubiquitin
分子名称: E3 ubiquitin-protein ligase ARIH1, Ubiquitin C variant, Ubiquitin-conjugating enzyme E2 L3, ...
著者Miller, D.J, Schulman, B.A.
登録日2016-12-27
公開日2017-06-14
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.24 Å)
主引用文献Structural Studies of HHARI/UbcH7Ub Reveal Unique E2Ub Conformational Restriction by RBR RING1.
Structure, 25, 2017
5MNJ
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BU of 5mnj by Molmil
Structure of MDM2-MDMX-UbcH5B-ubiquitin complex
分子名称: E3 ubiquitin-protein ligase Mdm2, Polyubiquitin-B, Protein Mdm4, ...
著者Klejnot, M, Huang, D.T.
登録日2016-12-13
公開日2017-05-31
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Structural analysis of MDM2 RING separates degradation from regulation of p53 transcription activity.
Nat. Struct. Mol. Biol., 24, 2017
5MN9
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BU of 5mn9 by Molmil
Crystal structure of MINDY-1 tMIU in complex with K48-diUb
分子名称: Ubiquitin carboxyl-terminal hydrolase MINDY-1, Ubiquitin-40S ribosomal protein S27a
著者Kristariyanto, Y.A, Abdul Rehman, S.A, Kulathu, Y.
登録日2016-12-13
公開日2017-01-25
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献A single MIU motif of MINDY-1 recognizes K48-linked polyubiquitin chains.
EMBO Rep., 18, 2017
5U4P
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BU of 5u4p by Molmil
Protein-protein complex between 26S proteasome regulatory subunit RPN8, RPN11, and Ubiquitin S31
分子名称: 26S proteasome regulatory subunit RPN11, 26S proteasome regulatory subunit RPN8, Ubiquitin-40S ribosomal protein S31, ...
著者Worden, E.J, Dong, K.C, Martin, A.
登録日2016-12-05
公開日2017-09-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献An AAA Motor-Driven Mechanical Switch in Rpn11 Controls Deubiquitination at the 26S Proteasome.
Mol. Cell, 67, 2017
5WQ4
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BU of 5wq4 by Molmil
Crystal structure of OPTN and linear diubiquitin complex
分子名称: Optineurin, ubiquitin
著者Li, F, Pan, L.
登録日2016-11-23
公開日2017-12-06
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural insights into the ubiquitin recognition by OPTN (optineurin) and its regulation by TBK1-mediated phosphorylation.
Autophagy, 14, 2018
5H7S
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BU of 5h7s by Molmil
Structural basis of the flanking zinc-finger motifs crucial for the E3 ligase activity of the LNX1 RING domain
分子名称: E3 ubiquitin-protein ligase LNX, Ubiquitin-conjugating enzyme E2 N, Ubiquitin-like 1, ...
著者Nayak, D, Sivaraman, J.
登録日2016-11-21
公開日2017-11-29
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.49 Å)
主引用文献Structure of LNX1:Ubc13~Ubiquitin Complex Reveals the Role of Additional Motifs for the E3 Ligase Activity of LNX1.
J. Mol. Biol., 430, 2018
5TXK
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BU of 5txk by Molmil
CRYSTAL STRUCTURE OF USP35 C450S IN COMPLEX WITH UBIQUITIN
分子名称: 1,2-ETHANEDIOL, Polyubiquitin-B, SULFATE ION, ...
著者Bader, G, Weiss-Puxbaum, A, Zoephel, A.
登録日2016-11-17
公開日2018-05-09
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Expansion of DUB functionality generated by alternative isoforms - USP35, a case study.
J. Cell. Sci., 131, 2018
5MC6
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BU of 5mc6 by Molmil
Cryo-EM structure of a native ribosome-Ski2-Ski3-Ski8 complex from S. cerevisiae
分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
著者Schmidt, C, Kowalinski, E, Shanmuganathan, V, Defenouillere, Q, Braunger, K, Heuer, A, Pech, M, Namane, A, Berninghausen, O, Fromont-Racine, M, Jacquier, A, Conti, E, Becker, T, Beckmann, R.
登録日2016-11-09
公開日2017-01-18
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献The cryo-EM structure of a ribosome-Ski2-Ski3-Ski8 helicase complex.
Science, 354, 2016
5TUT
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BU of 5tut by Molmil
UbcH5a-Ub isopeptide conjugate
分子名称: Ubiquitin, Ubiquitin-conjugating enzyme E2 D1
著者Sanchez, J.G, Wagner, J.M, Pornillos, O.
登録日2016-11-07
公開日2017-11-08
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.604 Å)
主引用文献UbcH5a-Ub isopeptide conjugate
To be Published
5TTE
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BU of 5tte by Molmil
Crystal Structure of an RBR E3 ubiquitin ligase in complex with an E2-Ub thioester intermediate mimic
分子名称: E3 ubiquitin-protein ligase ARIH1, Ubiquitin-conjugating enzyme E2 L3, ZINC ION, ...
著者Yuan, L, Lv, Z, Olsen, S.K.
登録日2016-11-03
公開日2017-08-23
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.501 Å)
主引用文献Structural insights into the mechanism and E2 specificity of the RBR E3 ubiquitin ligase HHARI.
Nat Commun, 8, 2017
5M93
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BU of 5m93 by Molmil
Crystal structure of SdeA-modified ubiquitin.
分子名称: Polyubiquitin-B, SULFATE ION, alpha-D-ribofuranose
著者Kalayil, S, Bhogaraju, S, Dikic, I.
登録日2016-10-31
公開日2016-12-14
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.793 Å)
主引用文献Phosphoribosylation of Ubiquitin Promotes Serine Ubiquitination and Impairs Conventional Ubiquitination.
Cell, 167, 2016
5TR5
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BU of 5tr5 by Molmil
Solution structure of Serine 65 phosphorylated UBL domain from parkin
分子名称: E3 ubiquitin-protein ligase parkin
著者Aguirre, J.D, Dunkerley, K.M, Mercier, P, Shaw, G.S.
登録日2016-10-25
公開日2016-12-21
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structure of phosphorylated UBL domain and insights into PINK1-orchestrated parkin activation.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5TR4
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BU of 5tr4 by Molmil
Structure of Ubiquitin activating enzyme (Uba1) in complex with ubiquitin and TAK-243
分子名称: Ubiquitin, Ubiquitin-activating enzyme E1 1, [(1~{R},2~{R},3~{S},4~{R})-2,3-bis(oxidanyl)-4-[[2-[3-(trifluoromethylsulfanyl)phenyl]pyrazolo[1,5-a]pyrimidin-7-yl]amino]cyclopentyl]methyl sulfamate
著者Sintchak, M.D.
登録日2016-10-25
公開日2017-11-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Identification and Characterization of a Small Molecule Inhibitor of the Ubiquitin Activating Enzyme (TAK-243)
To be published
5TOG
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BU of 5tog by Molmil
Room temperature structure of ubiquitin variant u7ub25.2540
分子名称: Polyubiquitin-B, SULFATE ION
著者Biel, J.T, Thompson, M.C, Cunningham, C.N, Corn, J.E, Fraser, J.S.
登録日2016-10-17
公開日2017-05-24
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.08 Å)
主引用文献Flexibility and Design: Conformational Heterogeneity along the Evolutionary Trajectory of a Redesigned Ubiquitin.
Structure, 25, 2017
5TOF
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BU of 5tof by Molmil
Room temperature structure of ubiquitin variant u7ub25
分子名称: Polyubiquitin-B, SULFATE ION
著者Biel, J.T, Thompson, M.C, Cunningham, C.N, Corn, J.E, Fraser, J.S.
登録日2016-10-17
公開日2017-05-24
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.12 Å)
主引用文献Flexibility and Design: Conformational Heterogeneity along the Evolutionary Trajectory of a Redesigned Ubiquitin.
Structure, 25, 2017
5TL7
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BU of 5tl7 by Molmil
Crystal structure of SARS-CoV papain-like protease in complex with C-terminal domain mouse ISG15
分子名称: Replicase polyprotein 1ab, Ubiquitin-like protein ISG15, ZINC ION
著者Daczkowski, C.D, Dzimianski, J.V, Pegan, S.D.
登録日2016-10-10
公開日2017-05-03
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献Structural Insights into the Interaction of Coronavirus Papain-Like Proteases and Interferon-Stimulated Gene Product 15 from Different Species.
J. Mol. Biol., 429, 2017
5TL6
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BU of 5tl6 by Molmil
Crystal structure of SARS-CoV papain-like protease in complex with the C-terminal domain of human ISG15
分子名称: Replicase polyprotein 1ab, SULFATE ION, Ubiquitin-like protein ISG15, ...
著者Dzimianski, J.V, Daczkowski, C.M, Pegan, S.D.
登録日2016-10-10
公開日2017-05-03
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.618 Å)
主引用文献Structural Insights into the Interaction of Coronavirus Papain-Like Proteases and Interferon-Stimulated Gene Product 15 from Different Species.
J. Mol. Biol., 429, 2017
5TLA
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BU of 5tla by Molmil
Crystal structure of mouse ISG15
分子名称: Ubiquitin-like protein ISG15
著者Goodwin, O.Y, Dzimianski, J.V, Daczkowski, C.M, Pegan, S.D.
登録日2016-10-10
公開日2017-05-03
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.244 Å)
主引用文献Structural Insights into the Interaction of Coronavirus Papain-Like Proteases and Interferon-Stimulated Gene Product 15 from Different Species.
J. Mol. Biol., 429, 2017
5H07
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BU of 5h07 by Molmil
TNIP2-Ub complex, C2 form
分子名称: Polyubiquitin-C, TNFAIP3-interacting protein 2
著者Lo, Y.C, Lin, S.C.
登録日2016-10-04
公開日2017-03-08
実験手法X-RAY DIFFRACTION (2.586 Å)
主引用文献Structural Insights into Linear Tri-ubiquitin Recognition by A20-Binding Inhibitor of NF-kappa B, ABIN-2
Structure, 25, 2017
5LZW
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BU of 5lzw by Molmil
Structure of the mammalian rescue complex with Pelota and Hbs1l assembled on a truncated mRNA.
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ...
著者Shao, S, Murray, J, Brown, A, Taunton, J, Ramakrishnan, V, Hegde, R.S.
登録日2016-10-02
公開日2016-11-30
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (3.53 Å)
主引用文献Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes.
Cell, 167, 2016
5LZU
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BU of 5lzu by Molmil
Structure of the mammalian ribosomal termination complex with accommodated eRF1
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ...
著者Shao, S, Murray, J, Brown, A, Taunton, J, Ramakrishnan, V, Hegde, R.S.
登録日2016-10-02
公開日2016-11-30
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.75 Å)
主引用文献Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes.
Cell, 167, 2016
5LZZ
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BU of 5lzz by Molmil
Structure of the mammalian rescue complex with Pelota and Hbs1l (combined)
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ...
著者Shao, S, Murray, J, Brown, A, Taunton, J, Ramakrishnan, V, Hegde, R.S.
登録日2016-10-02
公開日2016-11-30
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (3.47 Å)
主引用文献Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes.
Cell, 167, 2016
5LZY
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BU of 5lzy by Molmil
Structure of the mammalian rescue complex with Pelota and Hbs1l assembled on a polyadenylated mRNA.
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ...
著者Shao, S, Murray, J, Brown, A, Taunton, J, Ramakrishnan, V, Hegde, R.S.
登録日2016-10-02
公開日2016-11-30
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.99 Å)
主引用文献Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes.
Cell, 167, 2016

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