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8FC1
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Crystal structure of the Thermus thermophilus 70S ribosome in complex with protein Y, hygromycin A, and erythromycin at 2.50A resolution
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ...
著者Chen, C.-W, Syroegin, E.A, Svetlov, M.S, Polikanov, Y.S.
登録日2022-12-01
公開日2023-07-12
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural insights into the mechanism of overcoming Erm-mediated resistance by macrolides acting together with hygromycin-A.
Nat Commun, 14, 2023
6HN2
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Ternary complex of Estrogen Receptor alpha peptide and 14-3-3 sigma C42 mutant bound to disulfide fragment PPI stabilizer 5
分子名称: 14-3-3 protein sigma, 2-(3,4-dichlorophenyl)-~{N}-(2-sulfanylethyl)ethanamide, Estrogen Receptor, ...
著者Sijbesma, E, Hallenbeck, K.K, Leysen, S, Arkin, M.R, Ottmann, C.
登録日2018-09-13
公開日2019-02-27
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Site-Directed Fragment-Based Screening for the Discovery of Protein-Protein Interaction Stabilizers.
J. Am. Chem. Soc., 141, 2019
8FC2
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BU of 8fc2 by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with protein Y, hygromycin A, and azithromycin at 2.50A resolution
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ...
著者Chen, C.-W, Syroegin, E.A, Svetlov, M.S, Polikanov, Y.S.
登録日2022-12-01
公開日2023-07-12
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural insights into the mechanism of overcoming Erm-mediated resistance by macrolides acting together with hygromycin-A.
Nat Commun, 14, 2023
8FC5
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BU of 8fc5 by Molmil
Crystal structure of the A2058-N6-dimethylated Thermus thermophilus 70S ribosome in complex with protein Y, hygromycin A, and azithromycin at 2.65A resolution
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ...
著者Chen, C.-W, Syroegin, E.A, Svetlov, M.S, Polikanov, Y.S.
登録日2022-12-01
公開日2023-07-26
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structural insights into the mechanism of overcoming Erm-mediated resistance by macrolides acting together with hygromycin-A.
Nat Commun, 14, 2023
8FC4
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Crystal structure of the A2058-N6-dimethylated Thermus thermophilus 70S ribosome in complex with protein Y, hygromycin A, and erythromycin at 2.45A resolution
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ...
著者Chen, C.-W, Syroegin, E.A, Svetlov, M.S, Polikanov, Y.S.
登録日2022-12-01
公開日2023-07-26
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Structural insights into the mechanism of overcoming Erm-mediated resistance by macrolides acting together with hygromycin-A.
Nat Commun, 14, 2023
6HMU
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BU of 6hmu by Molmil
Ternary complex of Estrogen Receptor alpha peptide and 14-3-3 sigma C45 mutant bound to disulfide fragment PPI stabilizer 6
分子名称: 14-3-3 protein sigma, 2-(4-chloranylphenoxy)-2-methyl-~{N}-(3-sulfanylpropyl)propanamide, Estrogen receptor, ...
著者Sijbesma, E, Hallenbeck, K.K, Leysen, S, Arkin, M.R, Ottmann, C.
登録日2018-09-12
公開日2019-02-27
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Site-Directed Fragment-Based Screening for the Discovery of Protein-Protein Interaction Stabilizers.
J. Am. Chem. Soc., 141, 2019
6RLZ
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BU of 6rlz by Molmil
Crystal Structure of 14-3-3zeta in complex with a macrocyclic 8-mer peptide derived from ExoS
分子名称: 14-3-3 protein zeta/delta, EtMe
著者Wallraven, K, Grossmann, T.N, Hennig, S.
登録日2019-05-03
公開日2020-03-18
最終更新日2020-03-25
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Adapting free energy perturbation simulations for large macrocyclic ligands: how to dissect contributions from direct binding and free ligand flexibility.
Chem Sci, 11, 2020
5XV4
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BU of 5xv4 by Molmil
Crystal structure of ATG101-ATG13HORMA
分子名称: Autophagy-related protein 101, Autophagy-related protein 13
著者Kim, B.-W, Song, H.K.
登録日2017-06-26
公開日2018-07-04
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献The C-terminal region of ATG101 bridges ULK1 and PtdIns3K complex in autophagy initiation.
Autophagy, 14, 2018
7Z0H
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BU of 7z0h by Molmil
Structure of yeast RNA Polymerase III-Ty1 integrase complex at 2.6 A (focus subunit AC40).
分子名称: DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ...
著者Nguyen, P.Q, Huecas, S, Plaza-Pegueroles, A, Fernandez-Tornero, C.
登録日2022-02-22
公開日2023-04-05
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Structural basis of Ty1 integrase tethering to RNA polymerase III for targeted retrotransposon integration.
Nat Commun, 14, 2023
6TCH
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BU of 6tch by Molmil
Binary complex of 14-3-3 sigma and a high-affinity non-canonical 9-mer peptide binder
分子名称: 14-3-3 protein sigma, CHLORIDE ION, DLY-NVA-PPN-KCJ-SEP-PPN-B3S-BAL-PPN-LYS, ...
著者Somsen, B.A, Ottmann, C.
登録日2019-11-06
公開日2020-07-01
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.801 Å)
主引用文献Ultra-large chemical libraries for the discovery of high-affinity peptide binders.
Nat Commun, 11, 2020
2GTL
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BU of 2gtl by Molmil
Lumbricus Erythrocruorin at 3.5A resolution
分子名称: CALCIUM ION, CARBON MONOXIDE, Extracellular globin 2, ...
著者Royer Jr, W.E, Sharma, H, Strand, K, Knapp, J.E, Bhyravbhatla, B.
登録日2006-04-28
公開日2006-07-18
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Lumbricus erythrocruorin at 3.5 a resolution: architecture of a megadalton respiratory complex.
Structure, 14, 2006
9BTS
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BU of 9bts by Molmil
Crystal structure of the bacterioferritin (Bfr) and ferritin (Ftn) heterooligomer complex from Acinetobacter baumannii
分子名称: Bacterioferritin (Bfr), Ferritin (Ftn), PROTOPORPHYRIN IX CONTAINING FE, ...
著者Lovell, S, Liu, L, Battaile, K.P, Rivera, M.
登録日2024-05-15
公開日2024-08-14
最終更新日2024-08-21
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献The crystal structure of Acinetobacter baumannii bacterioferritin reveals a heteropolymer of bacterioferritin and ferritin subunits.
Sci Rep, 14, 2024
8Q4L
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BU of 8q4l by Molmil
GBP1 bound by 14-3-3sigma
分子名称: 14-3-3 protein sigma, Guanylate-binding protein 1
著者Pfleiderer, M.M, Liu, X, Fisch, D, Anastasakou, E, Frickel, E.M, Galej, W.P.
登録日2023-08-07
公開日2023-10-11
最終更新日2023-10-18
実験手法ELECTRON MICROSCOPY (5.12 Å)
主引用文献PIM1 controls GBP1 activity to limit self-damage and to guard against pathogen infection.
Science, 382, 2023
8P2H
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BU of 8p2h by Molmil
Staphylococcus aureus 70S ribosome with elongation factor G locked with fusidic acid with a tRNA in pe/E chimeric state
分子名称: 1,4-DIAMINOBUTANE, 16S ribosomal RNA, 23S ribosomal RNA, ...
著者Gonzalez-Lopez, A, Selmer, M.
登録日2023-05-16
公開日2024-05-01
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (2.49 Å)
主引用文献Structures of the Staphylococcus aureus ribosome inhibited by fusidic acid and fusidic acid cyclopentane.
Sci Rep, 14, 2024
8Q3E
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BU of 8q3e by Molmil
High Resolution Structure of Nucleosome Core with Bound Foamy Virus GAG Peptide
分子名称: DNA (145-MER), GLY-GLY-TYR-ASN-LEU-ARG-PRO-ARG-THR-TYR-GLN-PRO-GLN-ARG-TYR-GLY-GLY-GLY, Histone H2A type 1-B/E, ...
著者De Falco, L, Batchelor, L.K, Dyson, P.J, Davey, C.A.
登録日2023-08-04
公開日2024-03-27
実験手法X-RAY DIFFRACTION (2.174 Å)
主引用文献Viral peptide conjugates for metal-warhead delivery to chromatin.
Rsc Adv, 14, 2024
8Q3M
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BU of 8q3m by Molmil
Structure of Nucleosome Core with a Bound Kaposi Sarcoma Associated Herpesvirus LANA Peptide Having a Methionine to Ornithine Substitution
分子名称: DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-K, ...
著者De Falco, L, Batchelor, L.K, Dyson, P.J, Davey, C.A.
登録日2023-08-04
公開日2024-03-27
実験手法X-RAY DIFFRACTION (2.503 Å)
主引用文献Viral peptide conjugates for metal-warhead delivery to chromatin.
Rsc Adv, 14, 2024
8Q36
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BU of 8q36 by Molmil
Structure of Nucleosome Core with a Bound Metallopeptide Conjugate (Foamy Virus GAG Peptide-Au[I] Compound)
分子名称: DNA (145-MER), GAG structural protein, Histone H2A type 1-B/E, ...
著者De Falco, L, Batchelor, L.K, Dyson, P.J, Davey, C.A.
登録日2023-08-03
公開日2024-03-27
実験手法X-RAY DIFFRACTION (2.604 Å)
主引用文献Viral peptide conjugates for metal-warhead delivery to chromatin.
Rsc Adv, 14, 2024
8Q3X
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BU of 8q3x by Molmil
Structure of Nucleosome Core with a Bound Metallopeptide Conjugate (Kaposi Sarcoma Associated Herpesvirus LANA Peptide-Au[I] Compound)
分子名称: 4-diphenylphosphanylbenzoic acid, DNA (145-MER), GOLD ION, ...
著者De Falco, L, Batchelor, L.K, Dyson, P.J, Davey, C.A.
登録日2023-08-04
公開日2024-03-27
実験手法X-RAY DIFFRACTION (2.301 Å)
主引用文献Viral peptide conjugates for metal-warhead delivery to chromatin.
Rsc Adv, 14, 2024
4V52
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BU of 4v52 by Molmil
Crystal structure of the bacterial ribosome from Escherichia coli in complex with neomycin.
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Borovinskaya, M.A, Pai, R.D, Zhang, W, Schuwirth, B.-S, Holton, J.M, Hirokawa, G, Kaji, H, Kaji, A, Cate, J.H.D.
登録日2007-06-15
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.21 Å)
主引用文献Structural basis for aminoglycoside inhibition of bacterial ribosome recycling.
Nat.Struct.Mol.Biol., 14, 2007
8C83
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BU of 8c83 by Molmil
Cryo-EM structure of in vitro reconstituted Otu2-bound Ub-40S complex
分子名称: 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S11-A, ...
著者Ikeuchi, K, Buschauer, R, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
登録日2023-01-18
公開日2023-05-24
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Molecular basis for recognition and deubiquitination of 40S ribosomes by Otu2.
Nat Commun, 14, 2023
7Z31
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BU of 7z31 by Molmil
Structure of yeast RNA Polymerase III-Ty1 integrase complex at 2.7 A (focus subunit C11, no C11 C-terminal Zn-ribbon in the funnel pore).
分子名称: DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ...
著者Nguyen, P.Q, Huecas, S, Plaza-Pegueroles, A, Fernandez-Tornero, C.
登録日2022-03-01
公開日2023-04-05
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (2.76 Å)
主引用文献Structural basis of Ty1 integrase tethering to RNA polymerase III for targeted retrotransposon integration.
Nat Commun, 14, 2023
7Z30
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BU of 7z30 by Molmil
Structure of yeast RNA Polymerase III-Ty1 integrase complex at 2.9 A (focus subunit C11 terminal Zn-ribbon in the funnel pore).
分子名称: DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ...
著者Nguyen, P.Q, Fernandez-Tornero, C.
登録日2022-03-01
公開日2023-04-05
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural basis of Ty1 integrase tethering to RNA polymerase III for targeted retrotransposon integration.
Nat Commun, 14, 2023
1JNU
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BU of 1jnu by Molmil
Photoexcited structure of the plant photoreceptor domain, phy3 LOV2
分子名称: FLAVIN MONONUCLEOTIDE, PHY3 PROTEIN
著者Crosson, S, Moffat, K.
登録日2001-07-25
公開日2002-06-14
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Photoexcited structure of a plant photoreceptor domain reveals a light-driven molecular switch.
Plant Cell, 14, 2002
8FMW
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BU of 8fmw by Molmil
The structure of a hibernating ribosome in the Lyme disease pathogen
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Sharma, M.R, Manjari, S.R, Agrawal, E.K, Keshavan, P, Koripella, R.K, Majumdar, S, Marcinkiewicz, A.L, Lin, Y.P, Agrawal, R.K, Banavali, N.K.
登録日2022-12-25
公開日2023-11-08
実験手法ELECTRON MICROSCOPY (2.86 Å)
主引用文献The structure of a hibernating ribosome in a Lyme disease pathogen.
Nat Commun, 14, 2023
8FN2
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The structure of a 50S ribosomal subunit in the Lyme disease pathogen Borreliella burgdorferi
分子名称: 23S ribosomal RNA, 50S ribosomal protein L10, 50S ribosomal protein L11, ...
著者Sharma, M.R, Manjari, S.R, Agrawal, E.K, Keshavan, P, Koripella, R.K, Majumdar, S, Marcinkiewicz, A.L, Lin, Y.P, Agrawal, R.K, Banavali, N.K.
登録日2022-12-26
公開日2023-11-08
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献The structure of a hibernating ribosome in a Lyme disease pathogen.
Nat Commun, 14, 2023

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