PDB: 222624 件ウェブページステータス検索Chemie searchBIRD

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4HJ2	Crystal Structure Analysis of GSTA1-1 in complex with chlorambucil 分子名称: Glutathione S-transferase A1, L-gamma-glutamyl-S-(2-{[4-(3-carboxypropyl)phenyl](2-chloroethyl)amino}ethyl)-L-cysteinylglycine 著者 Karpusas, M, Chiniadis, L, Labrou, N.E. 登録日 2012-10-12 公開日 2013-03-27 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The interaction of the chemotherapeutic drug chlorambucil with human glutathione transferase A1-1: kinetic and structural analysis. Plos One, 8, 2013
3ELM	Crystal Structure of MMP-13 Complexed with Inhibitor 24f 分子名称: (2R)-({[5-(4-ethoxyphenyl)thiophen-2-yl]sulfonyl}amino){1-[(1-methylethoxy)carbonyl]piperidin-4-yl}ethanoic acid, CALCIUM ION, Collagenase 3, ... 著者 Kulathila, R, Monovich, L, Koehn, J. 登録日 2008-09-22 公開日 2009-07-21 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Discovery of potent, selective, and orally active carboxylic acid based inhibitors of matrix metalloproteinase-13 J.Med.Chem., 52, 2009
3EM6	Crystal structure of I50L/A71V mutant of hiv-1 protease in complex with inhibitor darunavir 分子名称: (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, ACETATE ION, PHOSPHATE ION, ... 著者 Royer, C.J, King, N.M, Prabu-Jeyabalan, M, Ng, C, Nalivaika, E.A, Schiffer, C.A. 登録日 2008-09-23 公開日 2009-09-01 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Kinetic and structural studies on atazanavir specific I50L drug-resistant HIV-1 protease mutant. To be Published
4HKO	Crystal Structures of Mutant Endo-beta-1,4-xylanase II (E177Q) in the apo form 分子名称: Endo-1,4-beta-xylanase 2, IODIDE ION 著者 Langan, P, Wan, Q, Coates, L, Kovalevsky, A. 登録日 2012-10-15 公開日 2014-01-08 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 X-ray crystallographic studies of family 11 xylanase Michaelis and product complexes: implications for the catalytic mechanism. Acta Crystallogr.,Sect.D, 70, 2014
4HPV	Crystal structure of S-Adenosylmethionine synthetase from Sulfolobus solfataricus 分子名称: S-adenosylmethionine synthase 著者 Wang, F, Hurley, K.A, Helmich, K.E, Singh, S, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) 登録日 2012-10-24 公開日 2012-11-14 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (2.214 Å) 主引用文献 Understanding molecular recognition of promiscuity of thermophilic methionine adenosyltransferase sMAT from Sulfolobus solfataricus. Febs J., 281, 2014
4MCO	Crystal structure of a TRAP periplasmic solute binding protein from Rhodoferax ferrireducens (Rfer_1840), target EFI-510211, with bound malonate 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, MALONATE ION, TRAP dicarboxylate transporter-DctP subunit 著者 Vetting, M.W, Toro, R, Bhosle, R, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Zhao, S, Stead, M, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Jacobson, M.P, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) 登録日 2013-08-21 公開日 2013-09-04 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Experimental strategies for functional annotation and metabolism discovery: targeted screening of solute binding proteins and unbiased panning of metabolomes. Biochemistry, 54, 2015
4MEV	Crystal structure of a TRAP periplasmic solute binding protein from Rhodoferax ferrireducens (Rfer_1840), Target EFI-510211, with bound malonate, space group I422 分子名称: CITRIC ACID, MALONATE ION, TRAP dicarboxylate transporter-DctP subunit 著者 Vetting, M.W, Toro, R, Bhosle, R, Al Obaidi, N.F, Zhao, S, Stead, M, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Jacobson, M.P, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) 登録日 2013-08-27 公開日 2013-09-04 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Experimental strategies for functional annotation and metabolism discovery: targeted screening of solute binding proteins and unbiased panning of metabolomes. Biochemistry, 54, 2015
3M9M	Crystal Structure of Dpo4 in complex with DNA containing the major cisplatin lesion 分子名称: CALCIUM ION, CYTIDINE-5'-TRIPHOSPHATE, Cisplatin, ... 著者 Wong, J.H.Y, Ling, H. 登録日 2010-03-22 公開日 2010-06-16 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural insight into dynamic bypass of the major cisplatin-DNA adduct by Y-family polymerase Dpo4. Embo J., 29, 2010
4HPS	Crystal Structure of a Pyrrolidone-carboxylate peptidase 1 (target ID NYSGRC-012831) from Xenorhabdus bovienii SS-2004 in space group P21 分子名称: CHLORIDE ION, Pyrrolidone-carboxylate peptidase 著者 Ghosh, A, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) 登録日 2012-10-24 公開日 2012-11-14 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Crystal Structure of a Pyrrolidone-carboxylate peptidase 1 (target ID NYSGRC-012831) from Xenorhabdus bovienii SS-2004 in space group P21 To be Published
3E87	Crystal structures of the kinase domain of AKT2 in complex with ATP-competitive inhibitors 分子名称: Glycogen synthase kinase-3 beta peptide, N-[(1S)-2-amino-1-phenylethyl]-5-(1H-pyrrolo[2,3-b]pyridin-4-yl)thiophene-2-carboxamide, RAC-beta serine/threonine-protein kinase 著者 Concha, N.O, Elkins, P.A, Smallwood, A, Ward, P. 登録日 2008-08-19 公開日 2008-10-14 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Aminofurazans as potent inhibitors of AKT kinase Bioorg.Med.Chem.Lett., 19, 2009
4HJ8	Crystal Structure of Schizosaccharomyces pombe Pot1pC bound to ssDNA (GGTTACGCT) 分子名称: DNA (5'-D(*GP*GP*TP*TP*AP*CP*GP*CP*T)-3'), Protection of telomeres protein 1 著者 Dickey, T.H, Wuttke, D.S. 登録日 2012-10-12 公開日 2012-12-12 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.043 Å) 主引用文献 Nonspecific Recognition Is Achieved in Pot1pC through the Use of Multiple Binding Modes. Structure, 21, 2013
3E8X	Putative NAD-dependent epimerase/dehydratase from Bacillus halodurans. 分子名称: CHLORIDE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Putative NAD-dependent epimerase/dehydratase 著者 Osipiuk, J, Skarina, T, Onopriyenko, O, Savchenko, A, Edwards, A.M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2008-08-20 公開日 2008-09-02 最終更新日 2017-10-25 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 X-ray crystal structure of putative NAD-dependent epimerase/dehydratase from Bacillus halodurans. To be Published
3MAK	Crystal structure of Glutathione transferase dmGSTD1 from Drosophila melanogaster, in complex with glutathione 分子名称: GLUTATHIONE, Glutathione S-transferase 1-1 著者 Wongsantichon, J, Robinson, R.C, Ketterman, A.J. 登録日 2010-03-24 公開日 2011-03-30 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural evidence for conformational changes of Delta class glutathione transferases after ligand binding Arch.Biochem.Biophys., 521, 2012
4HK7	Crystal structure of Cordyceps militaris IDCase in complex with uracil 分子名称: URACIL, Uracil-5-carboxylate decarboxylase, ZINC ION 著者 Xu, S, Zhu, J, Ding, J. 登録日 2012-10-15 公開日 2013-09-11 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.189 Å) 主引用文献 Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase. Cell Res., 23, 2013
4HL6	YfdE from Escherichia coli 分子名称: Uncharacterized protein YfdE 著者 Mullins, E.A, Sullivan, K.L, Nyffeler, K.E, Kappock, T.J. 登録日 2012-10-16 公開日 2013-05-22 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.12 Å) 主引用文献 Function and X-Ray crystal structure of Escherichia coli YfdE. Plos One, 8, 2013
4HID	Crystal Structure of Schizosaccharomyces pombe Pot1pC bound to ssDNA (GCTTACGGT) 分子名称: DNA (5'-D(*GP*CP*TP*TP*AP*CP*GP*GP*T)-3'), Protection of telomeres protein 1 著者 Dickey, T.H, Wuttke, D.S. 登録日 2012-10-11 公開日 2012-12-12 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.822 Å) 主引用文献 Nonspecific Recognition Is Achieved in Pot1pC through the Use of Multiple Binding Modes. Structure, 21, 2013
3MJM	His257Ala mutant of dihydroorotase from E. coli 分子名称: (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, Dihydroorotase, N-CARBAMOYL-L-ASPARTATE, ... 著者 Ernberg, K.E, Guss, J.M, Lee, M, Maher, M.J. 登録日 2010-04-13 公開日 2011-03-02 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 His257Ala mutant of dihydroorotase from E. coli To be Published
4HJA	Crystal Structure of Schizosaccharomyces pombe Pot1pC bound to ssDNA (ACGGTTACGGT) 分子名称: DNA (5'-D(*AP*CP*GP*GP*TP*TP*AP*CP*GP*GP*T)-3'), Protection of telomeres protein 1 著者 Dickey, T.H, Wuttke, D.S. 登録日 2012-10-12 公開日 2012-12-12 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Nonspecific Recognition Is Achieved in Pot1pC through the Use of Multiple Binding Modes. Structure, 21, 2013
4HJL	Naphthalene 1,2-Dioxygenase bound to 1-chloronaphthalene 分子名称: 1,2-ETHANEDIOL, 1-chloronaphthalene, FE (III) ION, ... 著者 Ferraro, D.J, Ramaswamy, S. 登録日 2012-10-12 公開日 2013-10-16 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Naphthalene 1,2-Dioxygenase bound to 1-chloronaphthalene TO BE PUBLISHED
3MCE	Crystal structure of the NAC domain of alpha subunit of nascent polypeptide-associated complex(NAC) 分子名称: IODIDE ION, Nascent polypeptide-associated complex subunit alpha 著者 Wang, L.F, Zhang, W.C, Wang, L, Zhang, X.J.C, Li, X.M, Rao, Z. 登録日 2010-03-29 公開日 2010-07-14 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.396 Å) 主引用文献 Crystal structures of NAC domains of human nascent polypeptide-associated complex (NAC) and its alphaNAC subunit Protein Cell, 1, 2010
3EBV	Crystal structure of putative Chitinase A from Streptomyces coelicolor. 分子名称: Chinitase A, SULFATE ION 著者 Vigdorovich, V, Ramagopal, U.A, Toro, R, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) 登録日 2008-08-28 公開日 2008-09-30 最終更新日 2021-02-10 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal structure of putative Chitinase A from Streptomyces coelicolor To be Published
4HK5	Crystal structure of Cordyceps militaris IDCase in apo form 分子名称: Uracil-5-carboxylate decarboxylase, ZINC ION 著者 Xu, S, Zhu, J, Ding, J. 登録日 2012-10-15 公開日 2013-09-11 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase. Cell Res., 23, 2013
4HNP	Crystal structure of yeast 20S proteasome in complex with vinylketone carmaphycin analogue VNK1 分子名称: N-hexanoyl-L-valyl-N~1~-[(3S,4S)-3-hydroxy-2,6-dimethylhept-1-en-4-yl]-N~5~,N~5~-dimethyl-L-glutamamide, N-hexanoyl-L-valyl-N~1~-[(3S,4S)-3-hydroxy-2,6-dimethylheptan-4-yl]-N~5~,N~5~-dimethyl-L-glutamamide, Proteasome component C1, ... 著者 Trivella, D.B.B, Stein, M, Groll, M. 登録日 2012-10-20 公開日 2014-01-29 最終更新日 2014-07-02 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Enzyme inhibition by hydroamination: design and mechanism of a hybrid carmaphycin-syringolin enone proteasome inhibitor. Chem.Biol., 21, 2014
4HRW	Identification of function and Mechanistic insights of Guanine deaminase from Nitrosomonas europaea 分子名称: 5-AMINO-1H-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDIN-7-OL, Cytidine and deoxycytidylate deaminase zinc-binding region, ZINC ION 著者 Anand, R, Bitra, A, Bhukya, H, Tanwar, A.S. 登録日 2012-10-29 公開日 2013-06-19 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.43 Å) 主引用文献 Identification of function and mechanistic insights of guanine deaminase from Nitrosomonas europaea: role of the C-terminal loop in catalysis Biochemistry, 52, 2013
4HM7	Naphthalene 1,2-Dioxygenase bound to styrene 分子名称: 1,2-ETHANEDIOL, FE (III) ION, FE2/S2 (INORGANIC) CLUSTER, ... 著者 Ferraro, D.J, Ramaswamy, S. 登録日 2012-10-17 公開日 2013-10-30 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Naphthalene 1,2-Dioxygenase bound to styrene To be Published

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