4HJ2
Crystal Structure Analysis of GSTA1-1 in complex with chlorambucil
Summary for 4HJ2
| Entry DOI | 10.2210/pdb4hj2/pdb |
| Descriptor | Glutathione S-transferase A1, L-gamma-glutamyl-S-(2-{[4-(3-carboxypropyl)phenyl](2-chloroethyl)amino}ethyl)-L-cysteinylglycine (3 entities in total) |
| Functional Keywords | alpha-beta, transferase |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm: P08263 |
| Total number of polymer chains | 2 |
| Total formula weight | 51218.88 |
| Authors | Karpusas, M.,Chiniadis, L.,Labrou, N.E. (deposition date: 2012-10-12, release date: 2013-03-27, Last modification date: 2024-02-28) |
| Primary citation | Karpusas, M.,Axarli, I.,Chiniadis, L.,Papakyriakou, A.,Bethanis, K.,Scopelitou, K.,Clonis, Y.D.,Labrou, N.E. The interaction of the chemotherapeutic drug chlorambucil with human glutathione transferase A1-1: kinetic and structural analysis. Plos One, 8:e56337-e56337, 2013 Cited by PubMed: 23460799DOI: 10.1371/journal.pone.0056337 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
Download full validation report
