PDB: 10970 件ウェブページステータス検索Chemie searchBIRD

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4QNA	MST3 IN COMPLEX WITH 2-(4,6-Diamino-1,3,5-triazin-2-yl)phenol 分子名称: 2-(4,6-diamino-1,3,5-triazin-2-yl)phenol, SERINE/THREONINE-PROTEIN KINASE 24 著者 Olesen, S.H, Watts, C, Zhu, J.-Y, Schonbrunn, E. 登録日 2014-06-17 公開日 2015-07-01 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.849 Å) 主引用文献 Discovery of Diverse Small-Molecule Inhibitors of Mammalian Sterile20-like Kinase 3 (MST3). Chemmedchem, 11, 2016
4IS8	Divergent sequence tunes ligand sensitivity in phospholipid-regulated hormone receptors 分子名称: Nuclear receptor subfamily 5 group A member 2 著者 Musille, P.M, Pathak, M.C, Ortlund, E.A. 登録日 2013-01-16 公開日 2013-06-12 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.78 Å) 主引用文献 Divergent Sequence Tunes Ligand Sensitivity in Phospholipid-regulated Hormone Receptors. J.Biol.Chem., 288, 2013
4QMT	MST3 in complex with HESPERADIN 分子名称: 1,2-ETHANEDIOL, N-[2-OXO-3-((E)-PHENYL{[4-(PIPERIDIN-1-YLMETHYL)PHENYL]IMINO}METHYL)-2,6-DIHYDRO-1H-INDOL-5-YL]ETHANESULFONAMIDE, Serine/threonine-protein kinase 24 著者 Olesen, S.H, Watts, C, Zhu, J.-Y, Schonbrunn, E. 登録日 2014-06-16 公開日 2015-07-01 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Discovery of Diverse Small-Molecule Inhibitors of Mammalian Sterile20-like Kinase 3 (MST3). Chemmedchem, 11, 2016
4IV6	X-ray crystal structure of an isovaleryl-CoA dehydrogenase from Mycobacterium smegmatis 分子名称: Acyl-CoA dehydrogenase FadE3, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2013-01-22 公開日 2013-03-20 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
4J2M	Molecular Engineering of Organophosphate Hydrolysis Activity from a Weak Promiscuous Lactonase Template 分子名称: COBALT (II) ION, Phosphotriesterase, putative 著者 Rajendran, C, Meier, M, Reinhard, S. 登録日 2013-02-04 公開日 2013-07-24 最終更新日 2013-09-04 実験手法 X-RAY DIFFRACTION (1.786 Å) 主引用文献 Molecular engineering of organophosphate hydrolysis activity from a weak promiscuous lactonase template. J.Am.Chem.Soc., 135, 2013
4QXV	CRYSTAL STRUCTURE of HUMAN TRANSTHYRETIN IN COMPLEX WITH LUTEOLIN AT 1.1 A RESOLUTION 分子名称: 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one, GLYCEROL, SODIUM ION, ... 著者 Begum, A, Olofsson, A, Sauer-Eriksson, A.E. 登録日 2014-07-22 公開日 2015-06-03 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.12 Å) 主引用文献 The flavonoid luteolin, but not luteolin-7-o-glucoside, prevents a transthyretin mediated toxic response. Plos One, 10, 2015
4ISO	Crystal Structure of Matriptase in complex with its inhibitor HAI-1 分子名称: DI(HYDROXYETHYL)ETHER, GLUTATHIONE, GLYCEROL, ... 著者 Huang, M.D, Zhao, B.Y, Yuan, C, Li, R. 登録日 2013-01-16 公開日 2013-03-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Crystal structures of matriptase in complex with its inhibitor hepatocyte growth factor activator inhibitor-1. J.Biol.Chem., 288, 2013
4L1C	Crystal structure of Dimerized N-terminal Domain of MinC 分子名称: Probable septum site-determining protein MinC 著者 An, J.Y, Kim, T.G, Park, K.R, Lee, J.G, Youn, H.S, Kang, J.Y, Lee, Y, Kang, G.B, Eom, S.H. 登録日 2013-06-03 公開日 2013-10-23 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Crystal structure of the N-terminal domain of MinC dimerized via domain swapping. J Synchrotron Radiat, 20, 2013
4J1Y	The X-ray crystal structure of human complement protease C1s zymogen 分子名称: Complement C1s subcomponent 著者 Perry, A.J, Wijeyewickrema, L.C, Wilmann, P.G, Gunzburg, M.J, D'Andrea, L, Irving, J.A, Pang, S.S, Duncan, R.C, Wilce, J.A, Whisstock, J.C, Pike, R.N. 登録日 2013-02-03 公開日 2013-04-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.6645 Å) 主引用文献 A Molecular Switch Governs the Interaction between the Human Complement Protease C1s and Its Substrate, Complement C4. J.Biol.Chem., 288, 2013
4L58	Crystal structure of the MLL5 PHD finger in complex with H3K4me3 分子名称: Histone H3 peptide, Histone-lysine N-methyltransferase MLL5, ZINC ION 著者 Tong, Q, Ali, M, Kutateladze, T.G. 登録日 2013-06-10 公開日 2013-06-26 最終更新日 2013-07-24 実験手法 X-RAY DIFFRACTION (1.48 Å) 主引用文献 Molecular basis for chromatin binding and regulation of MLL5. Proc.Natl.Acad.Sci.USA, 110, 2013
4L0D	Crystal structure of delta516-525 human cystathionine beta-synthase containing C-terminal 6xHis-tag 分子名称: Cystathionine beta-synthase, PROTOPORPHYRIN IX CONTAINING FE, PYRIDOXAL-5'-PHOSPHATE 著者 Ereno, J, Majtan, T, Oyenarte, I, Kraus, J.P, Martinez-Cruz, L.A. 登録日 2013-05-31 公開日 2013-09-18 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.97 Å) 主引用文献 Structural basis of regulation and oligomerization of human cystathionine beta-synthase, the central enzyme of transsulfuration. Proc.Natl.Acad.Sci.USA, 110, 2013
4J35	Molecular Engineering of Organophosphate Hydrolysis Activity from a Weak Promiscuous Lactonase Template 分子名称: COBALT (II) ION, Phosphotriesterase, putative 著者 Sterner, R, Raushel, F, Meier, M, Rajendran, C, Malisi, C, Fox, N, Schlee, S, Barondeau, D, Cker, B.H. 登録日 2013-02-05 公開日 2013-07-24 最終更新日 2013-09-04 実験手法 X-RAY DIFFRACTION (1.783 Å) 主引用文献 Molecular engineering of organophosphate hydrolysis activity from a weak promiscuous lactonase template. J.Am.Chem.Soc., 135, 2013
4IZ9	Crystal structure of an acetate kinase from Mycobacterium avium bound to an unknown acid-ApCpp conjugate and manganese 分子名称: 1,2-ETHANEDIOL, Acetate kinase, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2013-01-29 公開日 2013-02-20 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
4R5K	Crystal structure of the DnaK C-terminus (Dnak-SBD-B) 分子名称: CALCIUM ION, Chaperone protein DnaK, SULFATE ION 著者 Leu, J.I, Zhang, P, Murphy, M.E, Marmorstein, R, George, D.L. 登録日 2014-08-21 公開日 2014-09-10 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.7469 Å) 主引用文献 Structural Basis for the Inhibition of HSP70 and DnaK Chaperones by Small-Molecule Targeting of a C-Terminal Allosteric Pocket. Acs Chem.Biol., 9, 2014
4QRP	Crystal Structure of HLA B*0801 in complex with HSKKKCDEL and DD31 TCR 分子名称: Beta-2-microglobulin, DD31 TCR alpha chain, DD31 TCR beta chain, ... 著者 Gras, S, Berry, R, Lucet, I.S, Rossjohn, J. 登録日 2014-07-02 公開日 2014-11-12 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 An Extensive Antigenic Footprint Underpins Immunodominant TCR Adaptability against a Hypervariable Viral Determinant. J.Immunol., 193, 2014
4IT7	Crystal structure of Al-CPI 分子名称: CPI 著者 Mei, G.Q, Liu, S.L, Sun, M.Z, Liu, J. 登録日 2013-01-17 公開日 2014-01-29 最終更新日 2014-06-11 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural Basis for the Immunomodulatory Function of Cysteine Protease Inhibitor from Human Roundworm Ascaris lumbricoides. Plos One, 9, 2014
4J1G	Leanyer orthobunyavirus nucleoprotein-ssRNA complex 分子名称: Nucleocapsid, RNA (45-MER) 著者 Niu, F, Shaw, N, Wang, Y, Jiao, L, Ding, W, Li, X, Zhu, P, Upur, H, Ouyang, S, Cheng, G, Liu, Z.J. 登録日 2013-02-01 公開日 2013-04-10 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.789 Å) 主引用文献 Structure of the Leanyer orthobunyavirus nucleoprotein-RNA complex reveals unique architecture for RNA encapsidation. Proc.Natl.Acad.Sci.USA, 110, 2013
6I0N	Crystal structure of RlpA SPOR domain from Pseudomonas aeruginosa in complex with denuded glycan ended in anhNAM 分子名称: 2-(2-ACETYLAMINO-4-HYDROXY-6,8-DIOXA-BICYCLO[3.2.1]OCT-3-YLOXY)-PROPIONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-N-acetyl-beta-muramic acid-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Endolytic peptidoglycan transglycosylase RlpA 著者 Alcorlo, M, Hermoso, J.A. 登録日 2018-10-26 公開日 2019-11-13 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Structural basis of denuded glycan recognition by SPOR domains in bacterial cell division. Nat Commun, 10, 2019
6TC8	2'-F-arabinoguanosine and 2'-F-riboguanosine modified hybrid type G-quadruplex with V-loop 分子名称: DNA (5'-D(*GP*GP*GP*AP*TP*GP*GP*GP*AP*CP*AP*CP*AP*(GFL)P*(GF2)P*GP*GP*AP*CP*GP*GP*G)-3') 著者 Haase, L, Weisz, K. 登録日 2019-11-05 公開日 2020-03-25 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Switching the type of V-loop in sugar-modified G-quadruplexes through altered fluorine interactions. Chem.Commun.(Camb.), 56, 2020
4RA0	An engineered Axl 'decoy receptor' effectively silences the Gas6-Axl signaling axis 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ... 著者 Kariolis, M.S, Kapur, S, Mathews, I.I, Cochran, J.R. 登録日 2014-09-09 公開日 2014-09-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.07 Å) 主引用文献 An engineered Axl 'decoy receptor' effectively silences the Gas6-Axl signaling axis. Nat.Chem.Biol., 10, 2014
4O2D	Crystal structure of aspartyl-tRNA synthetase from Mycobacterium smegmatis with bound aspartic acid 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ASPARTIC ACID, Aspartate--tRNA ligase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2013-12-17 公開日 2014-01-22 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
4QWN	Histone demethylase KDM2A-H3K36ME1-alpha-KG complex structure 分子名称: 2-OXOGLUTARIC ACID, Histone H3.2, Lysine-specific demethylase 2A, ... 著者 Cheng, Z.J, Patel, D.J. 登録日 2014-07-16 公開日 2014-11-05 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 A molecular threading mechanism underlies Jumonji lysine demethylase KDM2A regulation of methylated H3K36. Genes Dev., 28, 2014
4IFI	Structure of human BRCA1 BRCT in complex with BAAT peptide 分子名称: ACETATE ION, BAAT peptide, Breast cancer type 1 susceptibility protein 著者 Liu, X, Ladias, J.A.A. 登録日 2012-12-14 公開日 2013-10-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural Basis for the BRCA1 BRCT Interaction with the Proteins ATRIP and BAAT1. Biochemistry, 52, 2013
2YDA	Sulfolobus sulfataricus 2-keto-3-deoxygluconate aldolase Y103F,Y130F, A198F variant 分子名称: 2-KETO-3-DEOXY GLUCONATE ALDOLASE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, ... 著者 Crennell, S.J, Royer, S.F, Angelopoulou, M, Hough, D.W, Danson, M.J, Bull, S.D. 登録日 2011-03-18 公開日 2012-03-28 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Sulfolobus Sulfataricus 2-Keto-3-Deoxygluconate Aldolase To be Published
6HTL	Measles Phosphoprotein Coiled-Coil Domain IPKI Variant 分子名称: CALCIUM ION, Phosphoprotein 著者 Schramm, A, Longhi, S. 登録日 2018-10-04 公開日 2019-06-05 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Regulation of measles virus gene expression by P protein coiled-coil properties. Sci Adv, 5, 2019

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