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6V75
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Crystal Structure of Human PKM2 in Complex with L-aspartate
分子名称: 1,6-di-O-phosphono-beta-D-fructofuranose, ASPARTIC ACID, CHLORIDE ION, ...
著者Nandi, S, Dey, M.
登録日2019-12-07
公開日2020-03-18
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Biochemical and structural insights into how amino acids regulate pyruvate kinase muscle isoform 2.
J.Biol.Chem., 295, 2020
6V7R
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BU of 6v7r by Molmil
Crystal structure of K37-acetylated SUMO1 in complex with PIAS-SIM2
分子名称: Protein PIAS, Small ubiquitin-related modifier 1
著者Lussier-Price, M, Wahba, H.M, Mascle, X.H, Cappadocia, L, Sakaguchi, K, Omichinski, J.G.
登録日2019-12-09
公開日2020-04-01
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.549 Å)
主引用文献Characterization of a C-Terminal SUMO-Interacting Motif Present in Select PIAS-Family Proteins.
Structure, 28, 2020
6UZA
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Cryo-EM structure of human TRPC6 in complex with antagonist AM-1473
分子名称: 2-[[(2~{S})-2-decanoyloxypropoxy]-oxidanyl-phosphoryl]oxyethyl-trimethyl-azanium, 4-({(1R,2R)-2-[(3R)-3-aminopiperidin-1-yl]-2,3-dihydro-1H-inden-1-yl}oxy)benzonitrile, CHOLESTEROL HEMISUCCINATE, ...
著者Bai, Y, Yu, X, Huang, X, Chen, H.
登録日2019-11-14
公開日2020-03-18
実験手法ELECTRON MICROSCOPY (3.08 Å)
主引用文献Structural basis for pharmacological modulation of the TRPC6 channel.
Elife, 9, 2020
1AZ3
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ECORV ENDONUCLEASE, UNLIGANDED, FORM B
分子名称: ECORV ENDONUCLEASE
著者Perona, J, Martin, A.
登録日1997-11-24
公開日1998-05-27
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Conformational transitions and structural deformability of EcoRV endonuclease revealed by crystallographic analysis.
J.Mol.Biol., 273, 1997
5EOU
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Pseudomonas aeruginosa PilM:PilN1-12 bound to ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, MAGNESIUM ION, ...
著者McCallum, M, Tammam, S, Robinson, H, Shah, M, Calmettes, C, Moraes, T, Burrows, L, Howell, L.P.
登録日2015-11-10
公開日2016-04-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献PilN Binding Modulates the Structure and Binding Partners of the Pseudomonas aeruginosa Type IVa Pilus Protein PilM.
J.Biol.Chem., 291, 2016
6WH1
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Structure of the complex of human DNA ligase III-alpha and XRCC1 BRCT domains
分子名称: DNA ligase 3 alpha, X-ray repair cross complementing protein 1 variant
著者Pourfarjam, Y, Ellenberger, T, Tainer, J.A, Tomkinson, A.E, Kim, I.K.
登録日2020-04-07
公開日2020-12-02
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献An atypical BRCT-BRCT interaction with the XRCC1 scaffold protein compacts human DNA Ligase III alpha within a flexible DNA repair complex.
Nucleic Acids Res., 49, 2021
6I4T
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BU of 6i4t by Molmil
Crystal structure of the disease-causing I445M mutant of the human dihydrolipoamide dehydrogenase
分子名称: Dihydrolipoyl dehydrogenase, mitochondrial, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Szabo, E, Wilk, P, Zambo, Z, Torocsik, B, Weiss, M.S, Adam-Vizi, V, Ambrus, A.
登録日2018-11-10
公開日2019-11-20
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.823 Å)
主引用文献Underlying molecular alterations in human dihydrolipoamide dehydrogenase deficiency revealed by structural analyses of disease-causing enzyme variants.
Hum.Mol.Genet., 28, 2019
3DPH
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BU of 3dph by Molmil
HIV-1 capsid C-terminal domain mutant (L211S)
分子名称: HIV-1 CAPSID PROTEIN
著者Igonet, S, Vaney, M.C, Rey, F.A.
登録日2008-07-08
公開日2008-09-02
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Residues in the HIV-1 Capsid Assembly Inhibitor Binding Site Are Essential for Maintaining the Assembly-competent Quaternary Structure of the Capsid Protein.
J.Biol.Chem., 283, 2008
6IR1
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Crystal structure of red fluorescent protein mCherry complexed with the nanobody LaM4 at 1.9 Angstron resolution
分子名称: MCherry fluorescent protein, mCherry's nanobody LaM4
著者Ding, Y, Wang, Z.Y, Hu, R.T, Chen, X.
登録日2018-11-09
公開日2019-11-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.919 Å)
主引用文献Structural insights into the binding of nanobodies LaM2 and LaM4 to the red fluorescent protein mCherry.
Protein Sci., 30, 2021
1B3N
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BETA-KETOACYL CARRIER PROTEIN SYNTHASE AS A DRUG TARGET, IMPLICATIONS FROM THE CRYSTAL STRUCTURE OF A COMPLEX WITH THE INHIBITOR CERULENIN.
分子名称: (2S, 3R)-3-HYDROXY-4-OXO-7,10-TRANS,TRANS-DODECADIENAMIDE, PROTEIN (KETOACYL ACYL CARRIER PROTEIN SYNTHASE 2)
著者Moche, M, Schneider, G, Edwards, P, Dehesh, K, Lindqvist, Y.
登録日1998-12-14
公開日1999-04-06
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structure of the complex between the antibiotic cerulenin and its target, beta-ketoacyl-acyl carrier protein synthase.
J.Biol.Chem., 274, 1999
6WH2
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Structure of the C-terminal BRCT domain of human XRCC1
分子名称: X-ray repair cross complementing protein 1 variant
著者Pourfarjam, Y, Ellenberger, T, Tainer, J.A, Tomkinson, A.E, Kim, I.K.
登録日2020-04-07
公開日2020-12-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.414 Å)
主引用文献An atypical BRCT-BRCT interaction with the XRCC1 scaffold protein compacts human DNA Ligase III alpha within a flexible DNA repair complex.
Nucleic Acids Res., 49, 2021
3DS3
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BU of 3ds3 by Molmil
HIV-1 capsid C-terminal domain mutant (Y169A) in complex with an inhibitor of particle assembly (CAI)
分子名称: HIV-1 CAPSID PROTEIN, Peptide inhibitor of capsid assembly
著者Igonet, S, Vaney, M.C, Rey, F.A.
登録日2008-07-11
公開日2008-09-02
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Residues in the HIV-1 Capsid Assembly Inhibitor Binding Site Are Essential for Maintaining the Assembly-competent Quaternary Structure of the Capsid Protein.
J.Biol.Chem., 283, 2008
3DS4
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BU of 3ds4 by Molmil
HIV-1 capsid C-terminal domain mutant (L211S) in complex with an inhibitor of particle assembly (CAI)
分子名称: HIV-1 CAPSID PROTEIN, Peptide inhibitor of capsid assembly
著者Igonet, S, Vaney, M.C, Rey, F.A.
登録日2008-07-11
公開日2008-09-02
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.12 Å)
主引用文献Residues in the HIV-1 Capsid Assembly Inhibitor Binding Site Are Essential for Maintaining the Assembly-competent Quaternary Structure of the Capsid Protein.
J.Biol.Chem., 283, 2008
6WN7
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BU of 6wn7 by Molmil
Homo sapiens S100A5
分子名称: CALCIUM ION, Protein S100-A5
著者Perkins, A, Harms, M.J, Wong, C.E, Wheeler, L.C.
登録日2020-04-22
公開日2020-09-30
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Learning peptide recognition rules for a low-specificity protein.
Protein Sci., 29, 2020
1B7Y
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PHENYLALANYL TRNA SYNTHETASE COMPLEXED WITH PHENYLALANINYL-ADENYLATE
分子名称: ADENOSINE-5'-[PHENYLALANINOL-PHOSPHATE], MAGNESIUM ION, PROTEIN (PHENYLALANYL-TRNA SYNTHETASE)
著者Reshetnikova, L, Moor, N, Lavrik, O, Vassylyev, D.G.
登録日1999-01-26
公開日2000-01-26
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structures of phenylalanyl-tRNA synthetase complexed with phenylalanine and a phenylalanyl-adenylate analogue.
J.Mol.Biol., 287, 1999
5FWZ
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Fasciola hepatica calcium binding protein FhCaBP2: Structure of the dynein light chain-like domain. P41212 mercury derivative.
分子名称: CALCIUM BINDING PROTEIN, CHLORIDE ION, MERCURY (II) ION
著者Nguyen, T.H, Thomas, C.M, Timson, D.J, van Raaij, M.J.
登録日2016-02-22
公開日2016-04-27
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Fasciola hepatica calcium-binding protein FhCaBP2: structure of the dynein light chain-like domain.
Parasitol. Res., 115, 2016
5G1Q
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BU of 5g1q by Molmil
Compressed conformation of Francisella tularensis ClpP at 2.84 A
分子名称: CLP PROTEASE PROTEOLYTIC SUBUNIT P
著者Diaz-Saez, L, Hunter, W.N.
登録日2016-03-29
公開日2016-10-19
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.84 Å)
主引用文献Open and compressed conformations of Francisella tularensis ClpP.
Proteins, 85, 2017
1CIA
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BU of 1cia by Molmil
REPLACEMENT OF CATALYTIC HISTIDINE-195 OF CHLORAMPHENICOL ACETYLTRANSFERASE: EVIDENCE FOR A GENERAL BASE ROLE FOR GLUTAMATE
分子名称: BETA-MERCAPTOETHANOL, CHLORAMPHENICOL ACETYLTRANSFERASE, COBALT (II) ION
著者Leslie, A.G.W, Gibbs, M.R.
登録日1993-07-19
公開日1994-01-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Replacement of catalytic histidine-195 of chloramphenicol acetyltransferase: evidence for a general base role for glutamate.
Biochemistry, 33, 1994
6IU3
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Crystal structure of iron transporter VIT1 with zinc ions
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, VIT1, ZINC ION
著者Kato, T, Nishizawa, T, Yamashita, K, Taniguchi, R, Kumazaki, K, Ishitani, R, Nureki, O.
登録日2018-11-27
公開日2019-02-06
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of plant vacuolar iron transporter VIT1.
Nat Plants, 5, 2019
6HZ1
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THE GLIC PENTAMERIC LIGAND-GATED ION CHANNEL MUTANT E243C
分子名称: ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ...
著者Hu, H.D, Delarue, M.
登録日2018-10-22
公開日2018-12-19
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Electrostatics, proton sensor, and networks governing the gating transition in GLIC, a proton-gated pentameric ion channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6HYW
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BU of 6hyw by Molmil
THE GLIC PENTAMERIC LIGAND-GATED ION CHANNEL MUTANT Y119F
分子名称: ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ...
著者Hu, H.D, Delarue, M.
登録日2018-10-22
公開日2018-12-19
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Electrostatics, proton sensor, and networks governing the gating transition in GLIC, a proton-gated pentameric ion channel.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
1D2S
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BU of 1d2s by Molmil
CRYSTAL STRUCTURE OF THE N-TERMINAL LAMININ G-LIKE DOMAIN OF SHBG IN COMPLEX WITH DIHYDROTESTOSTERONE
分子名称: 5-ALPHA-DIHYDROTESTOSTERONE, CALCIUM ION, SEX HORMONE-BINDING GLOBULIN
著者Grishkovskaya, I, Avvakumov, G.V, Sklenar, G, Dales, D, Hammond, G.L, Muller, Y.A.
登録日1999-09-28
公開日2000-06-28
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Crystal structure of human sex hormone-binding globulin: steroid transport by a laminin G-like domain.
EMBO J., 19, 2000
2BBF
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BU of 2bbf by Molmil
Crystal structure of tRNA-guanine transglycosylase (TGT) from Zymomonas mobilis in complex with 6-amino-3,7-dihydro-imidazo[4,5-g]quinazolin-8-one
分子名称: 6-AMINO-3,7-DIHYDRO-IMIDAZO[4,5-G]QUINAZOLIN-8-ONE, ZINC ION, tRNA guanine transglycosylase
著者Stengl, B, Meyer, E.A, Heine, A, Brenk, R, Diederich, F, Klebe, G.
登録日2005-10-17
公開日2007-04-24
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structures of tRNA-guanine transglycosylase (TGT) in complex with novel and potent inhibitors unravel pronounced induced-fit adaptations and suggest dimer formation upon substrate binding.
J.Mol.Biol., 370, 2007
3QZX
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3D Structure of ferric methanosarcina acetivorans protoglobin Y61A mutant with unknown ligand
分子名称: GLYCEROL, Methanosarcina acetivorans protoglobin, PHOSPHATE ION, ...
著者Pesce, A, Tilleman, L, Dewilde, S, Ascenzi, P, Coletta, M, Ciaccio, C, Bruno, S, Moens, L, Bolognesi, M, Nardini, M.
登録日2011-03-07
公開日2011-06-08
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Structural heterogeneity and ligand gating in ferric methanosarcina acetivorans protoglobin mutants.
Iubmb Life, 63, 2011
2HPI
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Eubacterial and Eukaryotic Replicative DNA Polymerases are not Homologous: X-ray Structure of DNA Polymerase III
分子名称: CHLORIDE ION, DNA polymerase III alpha subunit, MAGNESIUM ION, ...
著者Bailey, S, Wing, R.A, Steitz, T.A.
登録日2006-07-17
公開日2006-09-19
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The Structure of T. aquaticus DNA Polymerase III Is Distinct from Eukaryotic Replicative DNA Polymerases.
Cell(Cambridge,Mass.), 126, 2006

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