6WH1

Structure of the complex of human DNA ligase III-alpha and XRCC1 BRCT domains

Summary for 6WH1

• Entry DOI: 10.2210/pdb6wh1/pdb
• Descriptor: X-ray repair cross complementing protein 1 variant, DNA ligase 3 alpha (3 entities in total)
• Functional Keywords: dna ligase complex, dna repair, dna binding protein, dna binding protein-ligase complex, dna binding protein/ligase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 20383.17

Authors

Pourfarjam, Y.,Ellenberger, T.,Tainer, J.A.,Tomkinson, A.E.,Kim, I.K. (deposition date: 2020-04-07, release date: 2020-12-02, Last modification date: 2024-03-06)

• Primary citation: Hammel, M.,Rashid, I.,Sverzhinsky, A.,Pourfarjam, Y.,Tsai, M.S.,Ellenberger, T.,Pascal, J.M.,Kim, I.K.,Tainer, J.A.,Tomkinson, A.E.; An atypical BRCT-BRCT interaction with the XRCC1 scaffold protein compacts human DNA Ligase III alpha within a flexible DNA repair complex.; Nucleic Acids Res., 49:306-321, 2021; PubMed: 33330937; DOI: 10.1093/nar/gkaa1188

Experimental method

X-RAY DIFFRACTION (2.4 Å)