PDB: 97138 件ウェブページステータス検索Chemie searchBIRD

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2ZJL	Crystal structure of the human BACE1 catalytic domain in complex with N-[1-(5-bromo-2,3-dimethoxy-benzyl)-piperidin-4-yl]-4-mercapto-butyramide 分子名称: Beta-secretase 1, N-[1-(5-bromo-2,3-dimethoxybenzyl)piperidin-4-yl]-4-sulfanylbutanamide 著者 Randal, M, Lam, M.B, Lu, W, Romanowski, M.J. 登録日 2008-03-07 公開日 2009-01-20 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Fragment-based discovery of novel BACE1 inhibitors using Tethering technology To be Published
1POS	CRYSTAL STRUCTURE OF A NOVEL DISULFIDE-LINKED "TREFOIL" MOTIF FOUND IN A LARGE FAMILY OF PUTATIVE GROWTH FACTORS 分子名称: PORCINE PANCREATIC SPASMOLYTIC POLYPEPTIDE 著者 De, A, Brown, D, Gorman, M, Carr, M, Sanderson, M.R, Freemont, P.S. 登録日 1993-10-08 公開日 1994-01-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal structure of a disulfide-linked "trefoil" motif found in a large family of putative growth factors. Proc.Natl.Acad.Sci.USA, 91, 1994
2M2V	African Swine Fever Virus Pol X in the ternary complex with MgdGTP and DNA 分子名称: Repair DNA polymerase X 著者 Wu, W, Su, M, Tsai, M. 登録日 2013-01-03 公開日 2014-04-02 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 How a low-fidelity DNA polymerase chooses non-Watson-Crick from Watson-Crick incorporation. J.Am.Chem.Soc., 136, 2014
1PSD	THE ALLOSTERIC LIGAND SITE IN THE VMAX-TYPE COOPERATIVE ENZYME PHOSPHOGLYCERATE DEHYDROGENASE 分子名称: D-3-PHOSPHOGLYCERATE DEHYDROGENASE (PHOSPHOGLYCERATE DEHYDROGENASE), NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SERINE 著者 Schuller, D.J, Grant, G.A, Banaszak, L.J. 登録日 1995-05-02 公開日 1995-07-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 The allosteric ligand site in the Vmax-type cooperative enzyme phosphoglycerate dehydrogenase. Nat.Struct.Biol., 2, 1995
2PUV	The crystal structure of isomerase domain of glucosamine-6-phosphate synthase from Candida albicans 分子名称: 5-AMINO-5-DEOXY-1-O-PHOSPHONO-D-MANNITOL, ACETATE ION, SODIUM ION, ... 著者 Raczynska, J, Olchowy, J, Milewski, S, Rypniewski, W. 登録日 2007-05-09 公開日 2007-09-11 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The Crystal and Solution Studies of Glucosamine-6-phosphate Synthase from Candida albicans J.Mol.Biol., 372, 2007
2HKE	Mevalonate diphosphate decarboxylase from Trypanosoma brucei 分子名称: Diphosphomevalonate decarboxylase, putative, SULFATE ION 著者 Byres, E, Alphey, M.S, Hunter, W.N. 登録日 2006-07-04 公開日 2007-06-12 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal Structures of Trypanosoma brucei and Staphylococcus aureus Mevalonate Diphosphate Decarboxylase Inform on the Determinants of Specificity and Reactivity J.Mol.Biol., 371, 2007
2PUT	The crystal structure of isomerase domain of glucosamine-6-phosphate synthase from Candida albicans 分子名称: ACETATE ION, FRUCTOSE -6-PHOSPHATE, SODIUM ION, ... 著者 Raczynska, J, Olchowy, J, Milewski, S, Rypniewski, W. 登録日 2007-05-09 公開日 2007-09-11 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The Crystal and Solution Studies of Glucosamine-6-phosphate Synthase from Candida albicans J.Mol.Biol., 372, 2007
1WZE	Structural basis for alteration of cofactor specificity of Malate dehydrogenase from Thermus flavus 分子名称: Malate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Tomita, T, Fushinobu, S, Kuzuyama, T, Nishiyama, M. 登録日 2005-03-04 公開日 2006-03-14 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural basis for alteration of cofactor specificity of malate dehydrogenase from Thermus flavus to be published
4HSR	Crystal Structure of a class III engineered cephalosporin acylase 分子名称: 5,5-dihydroxy-L-norvaline, glutaryl-7-aminocephalosporanic acid acylase alpha chain, glutaryl-7-aminocephalosporanic acid acylase beta chain 著者 Vrielink, A, Golden, E, Patterson, R, Tie, W.J, Anandan, A, Flematti, G, Molla, G, Rosini, E, Pollegioni, L. 登録日 2012-10-30 公開日 2013-02-27 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.13 Å) 主引用文献 Structure of a class III engineered cephalosporin acylase: comparisons with class I acylase and implications for differences in substrate specificity and catalytic activity. Biochem.J., 451, 2013
1BMD	DETERMINANTS OF PROTEIN THERMOSTABILITY OBSERVED IN THE 1.9 ANGSTROMS CRYSTAL STRUCTURE OF MALATE DEHYDROGENASE FROM THE THERMOPHILIC BACTERIUM THERMUS FLAVUS 分子名称: MALATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Kelly, C.A, Birktoft, J.J. 登録日 1992-11-10 公開日 1994-07-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Determinants of protein thermostability observed in the 1.9-A crystal structure of malate dehydrogenase from the thermophilic bacterium Thermus flavus. Biochemistry, 32, 1993
7L7F	Cryo-EM structure of human ACE2 receptor bound to protein encoded by vaccine candidate BNT162b1 分子名称: Angiotensin-converting enzyme 2, Spike glycoprotein, Envelope glycoprotein fusion 著者 Lees, J.A, Han, S. 登録日 2020-12-28 公開日 2021-02-24 最終更新日 2021-04-21 実験手法 ELECTRON MICROSCOPY (3.24 Å) 主引用文献 BNT162b vaccines protect rhesus macaques from SARS-CoV-2. Nature, 592, 2021
6P9Y	PAC1 GPCR Receptor complex 分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... 著者 Belousoff, M.J, Liang, Y.L, Sexton, P, Danev, R. 登録日 2019-06-10 公開日 2020-02-05 最終更新日 2020-02-19 実験手法 ELECTRON MICROSCOPY (3.01 Å) 主引用文献 Toward a Structural Understanding of Class B GPCR Peptide Binding and Activation. Mol.Cell, 77, 2020
7L7K	Cryo-EM structure of protein encoded by vaccine candidate BNT162b2 分子名称: Spike glycoprotein 著者 Lees, J.A, Han, S. 登録日 2020-12-28 公開日 2021-02-24 最終更新日 2021-04-21 実験手法 ELECTRON MICROSCOPY (3.29 Å) 主引用文献 BNT162b vaccines protect rhesus macaques from SARS-CoV-2. Nature, 592, 2021
5MOA	ABA RECEPTOR FROM TOMATO, SlPYL1 分子名称: SlPYL1 著者 Moreno-Alvero, M, Yunta, C, Gonzalez-Guzman, M, Arbona, V, Granell, A, Martinez-Ripoll, M, Infantes, L, Rodriguez, P.L, Albert, A. 登録日 2016-12-14 公開日 2017-08-02 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structure of Ligand-Bound Intermediates of Crop ABA Receptors Highlights PP2C as Necessary ABA Co-receptor. Mol Plant, 10, 2017
5MTQ	Crystal structure of M. tuberculosis InhA inhibited by PT511 分子名称: 2-[4-[(4-cyclohexyl-1,2,3-triazol-1-yl)methyl]-2-oxidanyl-phenoxy]benzenecarbonitrile, Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Eltschkner, S, Pschibul, A, Spagnuolo, L.A, Yu, W, Tonge, P.J, Kisker, C. 登録日 2017-01-10 公開日 2017-02-15 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Evaluating the Contribution of Transition-State Destabilization to Changes in the Residence Time of Triazole-Based InhA Inhibitors. J. Am. Chem. Soc., 139, 2017
5MMQ	ABA RECEPTOR FROM CITRUS, CSPYL1 分子名称: CSPYL1 著者 Moreno-Alvero, M, Yunta, C, Gonzalez-Guzman, M, Arbona, V, Granell, A, Martinez-Ripoll, M, Infantes, L, Rodriguez, P.L. 登録日 2016-12-12 公開日 2017-08-02 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure of Ligand-Bound Intermediates of Crop ABA Receptors Highlights PP2C as Necessary ABA Co-receptor. Mol Plant, 10, 2017
5MN0	ABA RECEPTOR FROM CITRUS, CSPYL1 分子名称: (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid, CHLORIDE ION, CSPYL1, ... 著者 Moreno-Alvero, M, Yunta, C, Gonzalez-Guzman, M, Arbona, V, Granell, A, Martinez-Ripoll, M, Infantes, L, Rodriguez, P.L, Albert, A. 登録日 2016-12-12 公開日 2017-08-02 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure of Ligand-Bound Intermediates of Crop ABA Receptors Highlights PP2C as Necessary ABA Co-receptor. Mol Plant, 10, 2017
5MH6	D-2-hydroxyacid dehydrogenases (D2-HDH) from Haloferax mediterranei in complex with 2-ketohexanoic acid and NAD+ (1.35 A resolution) 分子名称: 1,2-ETHANEDIOL, 2-Ketohexanoic acid, D-2-hydroxyacid dehydrogenase, ... 著者 Bisson, C, Baker, P.J, Domenech Perez, J, Pramanpol, N, Harding, S.E, Rice, D.W, Ferrer, J. 登録日 2016-11-23 公開日 2018-06-06 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Productive ternary complexes of D-2-hydroxyacid dehydrogenase provide insights into the chiral specificity of its reaction mechanism To Be Published
4XH8	Crystal Structure of E112A/D230A Mutant of Stationary Phase Survival Protein (SurE) from Salmonella typhimurium 分子名称: 5'/3'-nucleotidase SurE 著者 Mathiharan, Y.K, Murthy, M.R.N. 登録日 2015-01-05 公開日 2015-09-09 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.56 Å) 主引用文献 Insights into stabilizing interactions in the distorted domain-swapped dimer of Salmonella typhimurium survival protein. Acta Crystallogr.,Sect.D, 71, 2015
5CNP	X-ray crystal structure of Spermidine n1-acetyltransferase from Vibrio cholerae. 分子名称: ISOPROPYL ALCOHOL, MAGNESIUM ION, Spermidine N(1)-acetyltransferase 著者 Osipiuk, J, VOLKART, L, MOY, S, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2015-07-17 公開日 2015-07-29 最終更新日 2019-12-11 実験手法 X-RAY DIFFRACTION (2.38 Å) 主引用文献 Substrate-Induced Allosteric Change in the Quaternary Structure of the Spermidine N-Acetyltransferase SpeG. J.Mol.Biol., 427, 2015
5MTP	Crystal structure of M. tuberculosis InhA inhibited by PT514 分子名称: 2-(2-methylphenoxy)-5-[(4-phenyl-1H-1,2,3-triazol-1-yl)methyl]phenol, CHLORIDE ION, Enoyl-[acyl-carrier-protein] reductase [NADH], ... 著者 Eltschkner, S, Pschibul, A, Spagnuolo, L.A, Yu, W, Tonge, P.J, Kisker, C. 登録日 2017-01-10 公開日 2017-02-15 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Evaluating the Contribution of Transition-State Destabilization to Changes in the Residence Time of Triazole-Based InhA Inhibitors. J. Am. Chem. Soc., 139, 2017
5C25	Crystal Structure of HIV-1 Reverse Transcriptase in Complex with 6-((4-((4-cyanophenyl)amino)-1,3,5-triazin-2-yl)amino)-5,7-dimethyl-2-naphthonitrile (JLJ639), a Non-nucleoside Inhibitor 分子名称: 6-({4-[(4-cyanophenyl)amino]-1,3,5-triazin-2-yl}amino)-5,7- dimethyl-2-naphthonitrile, HIV-1 REVERSE TRANSCRIPTASE, P51 SUBUNIT, ... 著者 Chan, A.H, Frey, K.M, Anderson, K.S. 登録日 2015-06-15 公開日 2015-07-29 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.841 Å) 主引用文献 Discovery and crystallography of bicyclic arylaminoazines as potent inhibitors of HIV-1 reverse transcriptase. Bioorg.Med.Chem.Lett., 25, 2015
7KSN	Crystal Structure of Sugarwin 分子名称: Sugarwin 著者 Maia, L.B.L, Pereira, H.M, Henrique-Silva, F, Garratt, R.C, Silva Filho, M.C. 登録日 2020-11-23 公開日 2021-09-22 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.51 Å) 主引用文献 Structural and Evolutionary Analyses of PR-4 SUGARWINs Points to a Different Pattern of Protein Function Frontiers in Plant Science, 12, 2021
5MVO	FoxE P43212 crystal structure of Rhodopseudomonas ferrooxidans SW2 putative iron oxidase 分子名称: COPPER (II) ION, FoxE, HEME C, ... 著者 Pereira, L, Saraiva, I.H, Oliveira, A.S, Soares, C, Gomes, R.O, Frazao, C. 登録日 2017-01-17 公開日 2018-02-28 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.668 Å) 主引用文献 Crystallization and preliminary crystallographic studies of FoxE from Rhodobacter ferrooxidans SW2, an Fe(II) oxidoreductase involved in photoferrotrophy. Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun., 68, 2012
5CBL	Crystal structure of the C-terminal domain of human galectin-4 with lactose 分子名称: BETA-MERCAPTOETHANOL, GLYCEROL, Galectin-4, ... 著者 Rustiguel, J.K, Nonato, M.C. 登録日 2015-07-01 公開日 2015-11-04 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.781 Å) 主引用文献 Recombinant expression, purification and preliminary biophysical and structural studies of C-terminal carbohydrate recognition domain from human galectin-4. Protein Expr.Purif., 118, 2015

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