PDB: 2894 件ウェブページステータス検索Chemie searchBIRD

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3G43	Crystal structure of the calmodulin-bound Cav1.2 C-terminal regulatory domain dimer 分子名称: CALCIUM ION, Calmodulin, Voltage-dependent L-type calcium channel subunit alpha-1C 著者 Fallon, J.L, Quiocho, F.A. 登録日 2009-02-03 公開日 2009-03-03 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of dimeric cardiac L-type calcium channel regulatory domains bridged by Ca2+{middle dot}calmodulins. Proc.Natl.Acad.Sci.USA, 106, 2009
3UU4	The GLIC pentameric Ligand-Gated Ion Channel Loop2-21' mutant reduced in the crystal in a locally-closed conformation (LC1 subtype) 分子名称: DODECYL-BETA-D-MALTOSIDE, Glr4197 protein 著者 Sauguet, L, Nury, H, Corringer, P.J, Delarue, M. 登録日 2011-11-28 公開日 2012-05-16 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.05 Å) 主引用文献 A locally closed conformation of a bacterial pentameric proton-gated ion channel. Nat.Struct.Mol.Biol., 19, 2012
3UU5	The GLIC pentameric Ligand-Gated Ion Channel Loop2-20' mutant reduced in solution 分子名称: CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, DODECYL-BETA-D-MALTOSIDE, ... 著者 Sauguet, L, Nury, H, Corringer, P.J, Delarue, M. 登録日 2011-11-28 公開日 2012-05-16 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 A locally closed conformation of a bacterial pentameric proton-gated ion channel. Nat.Struct.Mol.Biol., 19, 2012
3UU8	The GLIC pentameric Ligand-Gated Ion Channel Loop2-24' mutant reduced in solution 分子名称: CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, DODECYL-BETA-D-MALTOSIDE, ... 著者 Sauguet, L, Nury, H, Corringer, P.J, Delarue, M. 登録日 2011-11-28 公開日 2012-05-16 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.25 Å) 主引用文献 A locally closed conformation of a bacterial pentameric proton-gated ion channel. Nat.Struct.Mol.Biol., 19, 2012
3UU6	The GLIC pentameric Ligand-Gated Ion Channel Loop2-22' mutant reduced in solution 分子名称: CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, DODECYL-BETA-D-MALTOSIDE, ... 著者 Sauguet, L, Nury, H, Corringer, P.J, Delarue, M. 登録日 2011-11-28 公開日 2012-05-16 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.98 Å) 主引用文献 A locally closed conformation of a bacterial pentameric proton-gated ion channel. Nat.Struct.Mol.Biol., 19, 2012
3UUB	The GLIC pentameric Ligand-Gated Ion Channel Loop2-21' mutant reduced in solution 分子名称: CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, DODECYL-BETA-D-MALTOSIDE, ... 著者 Sauguet, L, Nury, H, Corringer, P.J, Delarue, M. 登録日 2011-11-28 公開日 2012-05-16 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 A locally closed conformation of a bacterial pentameric proton-gated ion channel. Nat.Struct.Mol.Biol., 19, 2012
6DAE	2.0 Angstrom crystal structure of the D95V Ca/CaM:CaV1.2 IQ domain complex 分子名称: CALCIUM ION, Calmodulin-1, Voltage-dependent L-type calcium channel subunit alpha-1C 著者 Wang, K, Lu, J, Van Petegem, F. 登録日 2018-05-01 公開日 2018-10-17 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Arrhythmia mutations in calmodulin cause conformational changes that affect interactions with the cardiac voltage-gated calcium channel. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6DAD	1.65 Angstrom crystal structure of the N97I Ca/CaM:CaV1.2 IQ domain complex 分子名称: CALCIUM ION, Calmodulin-1, Voltage-dependent L-type calcium channel subunit alpha-1C 著者 Wang, K, Van Petegem, F. 登録日 2018-05-01 公開日 2018-10-17 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Arrhythmia mutations in calmodulin cause conformational changes that affect interactions with the cardiac voltage-gated calcium channel. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
3UU3	The GLIC pentameric Ligand-Gated Ion Channel Loop2-20' oxidized mutant in a locally-closed conformation (LC1 subtype) 分子名称: DODECYL-BETA-D-MALTOSIDE, Glr4197 protein 著者 Sauguet, L, Nury, H, Corringer, P.J, Delarue, M. 登録日 2011-11-28 公開日 2012-05-16 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 A locally closed conformation of a bacterial pentameric proton-gated ion channel. Nat.Struct.Mol.Biol., 19, 2012
3TLU	The GLIC pentameric Ligand-Gated Ion Channel Loop2-24' oxidized mutant in a locally-closed conformation (LC1 subtype) 分子名称: CHLORIDE ION, DODECYL-BETA-D-MALTOSIDE, Glr4197 protein 著者 Sauguet, L, Nury, H, Corringer, P.J, Delarue, M. 登録日 2011-08-30 公開日 2012-05-16 最終更新日 2012-06-27 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 A locally closed conformation of a bacterial pentameric proton-gated ion channel. Nat.Struct.Mol.Biol., 19, 2012
3TLS	The GLIC pentameric Ligand-Gated Ion Channel E19'P mutant in a locally-closed conformation (LC2 subtype) 分子名称: CHLORIDE ION, DODECYL-BETA-D-MALTOSIDE, Glr4197 protein 著者 Sauguet, L, Nury, H, Corringer, P.J, Delarue, M. 登録日 2011-08-30 公開日 2012-05-16 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 A locally closed conformation of a bacterial pentameric proton-gated ion channel. Nat.Struct.Mol.Biol., 19, 2012
3TLT	The GLIC pentameric Ligand-Gated Ion Channel H11'F mutant in a locally-closed conformation (LC1 subtype) 分子名称: CHLORIDE ION, DODECYL-BETA-D-MALTOSIDE, Glr4197 protein 著者 Sauguet, L, Nury, H, Corringer, P.J, Delarue, M. 登録日 2011-08-30 公開日 2012-05-16 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 A locally closed conformation of a bacterial pentameric proton-gated ion channel. Nat.Struct.Mol.Biol., 19, 2012
3TLV	The GLIC pentameric Ligand-Gated Ion Channel Loop2-22' oxidized mutant in a locally-closed conformation (LC3 subtype) 分子名称: CHLORIDE ION, DODECYL-BETA-D-MALTOSIDE, Glr4197 protein 著者 Sauguet, L, Nury, H, Corringer, P.J, Delarue, M. 登録日 2011-08-30 公開日 2012-05-16 最終更新日 2012-06-27 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 A locally closed conformation of a bacterial pentameric proton-gated ion channel. Nat.Struct.Mol.Biol., 19, 2012
7UDV	Designed pentameric proton channel LLQL 分子名称: De novo designed proton channel LLQL 著者 Kratochvil, H.T, Thomaston, J.L, Liu, L, DeGrado, W.F. 登録日 2022-03-20 公開日 2022-04-06 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Transient water wires mediate selective proton transport in designed channel proteins. Nat.Chem., 15, 2023
1GMK	GRAMICIDIN/KSCN COMPLEX 分子名称: GRAMICIDIN A, METHANOL, POTASSIUM ION, ... 著者 Doyle, D.A, Wallace, B.A. 登録日 1996-07-09 公開日 1998-07-01 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal Structure of the Gramicidin/Potassium Thiocyanate Complex. J.Mol.Biol., 266, 1997
2I1T	Solution structure of Jingzhaotoxin-III, a novel toxin inhibiting both Nav and Kv channels 分子名称: Jingzhaotoxin-3 著者 Liao, Z, Peng, K, Liang, S. 登録日 2006-08-15 公開日 2006-08-29 最終更新日 2022-03-09 実験手法 SOLUTION NMR 主引用文献 Solution structure of Jingzhaotoxin-III, a novel toxin inhibiting both Nav and Kv channels To be Published
2MHF	Solution structure of the cyclic-nucleotide binding homology domain of a KCNH channel 分子名称: Uncharacterized protein 著者 Li, Q, Ng, H. 登録日 2013-11-21 公開日 2014-04-02 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Solution structure of the cyclic-nucleotide binding homology domain of a KCNH channel. J.Struct.Biol., 186, 2014
7YO2	Cryo-EM structure of RCK1-RCK2 mutated human Slo1 apo 分子名称: Calcium-activated potassium channel subunit alpha-1 著者 Yamanouchi, D, Nureki, O. 登録日 2022-08-01 公開日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structural basis for dual allosteric gating modulation of Slo1-LRRC channel complex To Be Published
7YO5	Cryo-EM structure of RCK1 mutated human Slo1 apo 分子名称: CALCIUM ION, Calcium-activated potassium channel subunit alpha-1 著者 Yamanouchi, D, Nureki, O. 登録日 2022-08-01 公開日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structural basis for dual allosteric gating modulation of Slo1-LRRC channel complex To Be Published
8THN	KcsA M96V mutant with Y78ester in High K+ 分子名称: KcsA Fab Heavy Chain, KcsA Fab Light Chain, POTASSIUM ION, ... 著者 Reddi, R, Valiyaveetil, F.I. 登録日 2023-07-17 公開日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 A facile approach for incorporating tyrosine esters to probe ion-binding sites and backbone hydrogen bonds. J.Biol.Chem., 300, 2023
3L4B	Crystal Structure of an Octomeric Two-Subunit TrkA K+ Channel Ring Gating Assembly, TM1088A:TM1088B, from Thermotoga maritima 分子名称: ADENOSINE MONOPHOSPHATE, TrkA K+ Channel protein TM1088A, TrkA K+ Channel protein TM1088B, ... 著者 Deller, M.C, Johnson, H.A, Miller, M, Spraggon, G, Wilson, I.A, Lesley, S.A, Joint Center for Structural Genomics (JCSG) 登録日 2009-12-18 公開日 2010-02-16 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.45 Å) 主引用文献 Crystal Structure of an Octomeric Two-Subunit TrkA K+ Channel Ring Gating Assembly, TM1088A:TM1088B, from Thermotoga maritima To be Published
6HRR	Structure of the TRPML2 ELD at pH 6.5 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, GLYCEROL, ... 著者 Bader, N, Viet, K.K, Wagner, A, Hellmich, U.A. 登録日 2018-09-28 公開日 2019-06-19 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure of the Human TRPML2 Ion Channel Extracytosolic/Lumenal Domain. Structure, 27, 2019
3P50	Structure of propofol bound to a pentameric ligand-gated ion channel, GLIC 分子名称: 2,6-BIS(1-METHYLETHYL)PHENOL, DIUNDECYL PHOSPHATIDYL CHOLINE, DODECYL-BETA-D-MALTOSIDE, ... 著者 Nury, H, Van Renterghem, C, Weng, Y, Tran, A, Baaden, M, Dufresne, V, Changeux, J.P, Sonner, J.M, Delarue, M, Corringer, P.J. 登録日 2010-10-07 公開日 2011-01-19 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 X-ray structures of general anaesthetics bound to a pentameric ligand-gated ion channel Nature, 469, 2011
3P4W	Structure of desflurane bound to a pentameric ligand-gated ion channel, GLIC 分子名称: (2S)-2-(difluoromethoxy)-1,1,1,2-tetrafluoroethane, DIUNDECYL PHOSPHATIDYL CHOLINE, DODECYL-BETA-D-MALTOSIDE, ... 著者 Nury, H, Van Renterghem, C, Weng, Y, Tran, A, Baaden, M, Dufresne, V, Changeux, J.P, Sonner, J.M, Delarue, M, Corringer, P.J. 登録日 2010-10-07 公開日 2011-01-19 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 X-ray structures of general anaesthetics bound to a pentameric ligand-gated ion channel Nature, 469, 2011
6IYX	Crystal Structure Analysis of a Eukaryotic Membrane Protein 分子名称: BROMIDE ION, CALCIUM ION, Trimeric intracellular cation channel type A 著者 Zeng, Y, Wang, X.H, Gao, F, Su, M, Chen, Y.H. 登録日 2018-12-17 公開日 2019-05-01 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural basis for activity of TRIC counter-ion channels in calcium release. Proc.Natl.Acad.Sci.USA, 116, 2019

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